Sonia Hernandez-Diaz

Summary

Affiliation: Boston University
Country: USA

Publications

  1. ncbi request reprint Folic acid antagonists during pregnancy and the risk of birth defects
    S Hernandez-Diaz
    Slone Epidemiology Unit, Boston University School of Public Health, Brookline, Mass 02446, USA
    N Engl J Med 343:1608-14. 2000
  2. ncbi request reprint Neural tube defects in relation to use of folic acid antagonists during pregnancy
    S Hernandez-Diaz
    Slone Epidemiology Unit, Boston University School of Public Health, Brookline, MA 02446, USA
    Am J Epidemiol 153:961-8. 2001
  3. ncbi request reprint Methylenetetrahydrofolate reductase polymorphisms and the risk of gestational hypertension
    Sonia Hernandez-Diaz
    Slone Epidemiology Center, Boston University School of Public Health, Boston, MA, USA
    Epidemiology 16:628-34. 2005
  4. ncbi request reprint Iatrogenic legacy from diethylstilbestrol exposure
    Sonia Hernandez-Diaz
    Slone Epidemiology Unit, Boston University School of Public Health, Brookline, MA 02446, USA
    Lancet 359:1081-2. 2002
  5. ncbi request reprint Risk of gestational hypertension in relation to folic acid supplementation during pregnancy
    Sonia Hernandez-Diaz
    Slone Epidemiology Center, Boston University School of Public Health, MA 02215, USA
    Am J Epidemiol 156:806-12. 2002
  6. ncbi request reprint Case-crossover and case-time-control designs in birth defects epidemiology
    Sonia Hernandez-Diaz
    Slone Epidemiology Center, Boston University School of Public Health, 1010 Commonwealth Avenue, Boston, MA 02215, USA
    Am J Epidemiol 158:385-91. 2003
  7. pmc Use of topiramate in pregnancy and risk of oral clefts
    Andrea V Margulis
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Obstet Gynecol 207:405.e1-7. 2012
  8. doi request reprint Antidepressant use and risk for preeclampsia
    Kristin Palmsten
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Epidemiology 24:682-91. 2013
  9. pmc Use of antidepressants near delivery and risk of postpartum hemorrhage: cohort study of low income women in the United States
    Kristin Palmsten
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    BMJ 347:f4877. 2013
  10. pmc Antidepressant use during pregnancy and the risk of preterm delivery and fetal growth restriction
    Sengwee Toh
    Department of Population Medicine, Harvard Medical School Harvard Pilgrim Health Care Institute, 133 Brookline Ave 6th Floor, Boston, MA 02215, USA
    J Clin Psychopharmacol 29:555-60. 2009

Detail Information

Publications71

  1. ncbi request reprint Folic acid antagonists during pregnancy and the risk of birth defects
    S Hernandez-Diaz
    Slone Epidemiology Unit, Boston University School of Public Health, Brookline, Mass 02446, USA
    N Engl J Med 343:1608-14. 2000
    ..We evaluated whether the folic acid component of multivitamins is responsible for the reduction in risk by examining the associations between maternal use of folic acid antagonists and these congenital malformations...
  2. ncbi request reprint Neural tube defects in relation to use of folic acid antagonists during pregnancy
    S Hernandez-Diaz
    Slone Epidemiology Unit, Boston University School of Public Health, Brookline, MA 02446, USA
    Am J Epidemiol 153:961-8. 2001
    ..These findings suggest that a number of FAAs may increase NTD risk, and they provide estimates of risk for selected drugs...
  3. ncbi request reprint Methylenetetrahydrofolate reductase polymorphisms and the risk of gestational hypertension
    Sonia Hernandez-Diaz
    Slone Epidemiology Center, Boston University School of Public Health, Boston, MA, USA
    Epidemiology 16:628-34. 2005
    ..It is also unknown whether the fetal genotype is relevant, or whether folic acid supplementation modifies this association...
  4. ncbi request reprint Iatrogenic legacy from diethylstilbestrol exposure
    Sonia Hernandez-Diaz
    Slone Epidemiology Unit, Boston University School of Public Health, Brookline, MA 02446, USA
    Lancet 359:1081-2. 2002
  5. ncbi request reprint Risk of gestational hypertension in relation to folic acid supplementation during pregnancy
    Sonia Hernandez-Diaz
    Slone Epidemiology Center, Boston University School of Public Health, MA 02215, USA
    Am J Epidemiol 156:806-12. 2002
    ..55 (95% confidence interval: 0.39, 0.79). This finding suggests that folic acid-containing multivitamins may reduce the risk of gestational hypertension...
  6. ncbi request reprint Case-crossover and case-time-control designs in birth defects epidemiology
    Sonia Hernandez-Diaz
    Slone Epidemiology Center, Boston University School of Public Health, 1010 Commonwealth Avenue, Boston, MA 02215, USA
    Am J Epidemiol 158:385-91. 2003
    ..9 (95% CI: 1.2, 7.2), but it requires controls. In the presence of gestational time trends of exposure, the new designs do not offer clear advantages over the case-control design...
  7. pmc Use of topiramate in pregnancy and risk of oral clefts
    Andrea V Margulis
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Obstet Gynecol 207:405.e1-7. 2012
    ..The objective of this study was to evaluate the association between the use of monotherapy topiramate in pregnancy and cleft lip with or without cleft palate (CL/P) in the offspring...
  8. doi request reprint Antidepressant use and risk for preeclampsia
    Kristin Palmsten
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Epidemiology 24:682-91. 2013
    ..US nationwide Medicaid Analytic eXtract (MAX) data have not been used to study medication safety during pregnancy...
  9. pmc Use of antidepressants near delivery and risk of postpartum hemorrhage: cohort study of low income women in the United States
    Kristin Palmsten
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    BMJ 347:f4877. 2013
    ..To determine whether use of serotonin or non-serotonin reuptake inhibitors near to delivery is associated with postpartum hemorrhage...
  10. pmc Antidepressant use during pregnancy and the risk of preterm delivery and fetal growth restriction
    Sengwee Toh
    Department of Population Medicine, Harvard Medical School Harvard Pilgrim Health Care Institute, 133 Brookline Ave 6th Floor, Boston, MA 02215, USA
    J Clin Psychopharmacol 29:555-60. 2009
    ..The associations between prenatal exposure to antidepressants and preterm delivery and fetal growth restriction are controversial and poorly understood. We studied the relation between antidepressant use and these outcomes...
  11. pmc Drug certainty-response in interview-based studies
    Wai Ping Yau
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Pharmacoepidemiol Drug Saf 20:1210-6. 2011
    ..Imperfect recall of exposure timing challenges the ascertainment of medications in interview-based studies...
  12. pmc Estimating absolute risks in the presence of nonadherence: an application to a follow-up study with baseline randomization
    Sengwee Toh
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02215, USA
    Epidemiology 21:528-39. 2010
    ..64; 95% CI = 1.24 to 2.18). The methods described here are also applicable to observational studies with time-varying treatments...
  13. pmc Maternal exposure to amoxicillin and the risk of oral clefts
    Kueiyu Joshua Lin
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Epidemiology 23:699-705. 2012
    ..Prior studies have suggested an increased risk of oral clefts after exposure to amoxicillin in early pregnancy, but findings have been inconsistent...
  14. pmc Asthma in pregnancy and its pharmacologic treatment
    Carol Louik
    Slone Epidemiology Center at Boston University, Boston, Massachusetts 02215, USA
    Ann Allergy Asthma Immunol 105:110-7. 2010
    ..Asthma is among the most common serious medical problems in pregnancy, and its prevalence may be increasing. Management is problematic because asthma may harm the fetus, yet little is known about fetal risks of asthma medications...
  15. ncbi request reprint First-trimester use of selective serotonin-reuptake inhibitors and the risk of birth defects
    Carol Louik
    Slone Epidemiology Center at Boston University, Boston, MA 02215, USA
    N Engl J Med 356:2675-83. 2007
    ..The risk of birth defects after antenatal exposure to selective serotonin-reuptake inhibitors (SSRIs) remains controversial...
  16. pmc Medications as a potential source of exposure to phthalates among women of childbearing age
    Sonia Hernandez-Diaz
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Reprod Toxicol 37:1-5. 2013
    ..To evaluate the association between the use of medications potentially containing phthalates and urinary concentrations of specific phthalate metabolites around conception...
  17. doi request reprint Newer anticonvulsants: lamotrigine, topiramate and gabapentin
    Lewis B Holmes
    Genetics Unit, MassGeneral Hospital for Children, Department of Pediatrics, Harvard Medical School, Boston, Massachusetts 02114, USA
    Birth Defects Res A Clin Mol Teratol 94:599-606. 2012
    ..Larger sample sizes are needed to clarify the questions that have been raised...
  18. pmc Medications used to treat nausea and vomiting of pregnancy and the risk of selected birth defects
    Marlene Anderka
    Center for Birth Defects Research and Prevention, Massachusetts Department of Public Health, Boston, Massachusetts 02108, USA
    Birth Defects Res A Clin Mol Teratol 94:22-30. 2012
    ..Several medications are used for the treatment of NVP; however, data are limited on their possible associations with birth defects...
  19. ncbi request reprint Smoking and the risk of oral clefts: exploring the impact of study designs
    Katie A Meyer
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    Epidemiology 15:671-8. 2004
    ..We used case-crossover, case-time-control, and bidirectional case-crossover designs to supplement findings from a case-control study of maternal smoking and oral clefts among offspring in a large birth registry...
  20. doi request reprint Methylergonovine maleate and the risk of myocardial ischemia and infarction
    Brian T Bateman
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Boston, MA Department of Anesthesiology, Critical Care, and Pain Medicine, Massachusetts General Hospital, Boston, MA Harvard Medical School, Boston, MA
    Am J Obstet Gynecol 209:459.e1-459.e13. 2013
    ....
  21. doi request reprint National trends in antidepressant medication treatment among publicly insured pregnant women
    Krista F Huybrechts
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
    Gen Hosp Psychiatry 35:265-71. 2013
    ..The risk of depression in women is greatest at childbearing age. We sought to examine and explain national trends in antidepressant use in pregnant women...
  22. ncbi request reprint Causal knowledge as a prerequisite for confounding evaluation: an application to birth defects epidemiology
    Miguel A Hernán
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Epidemiol 155:176-84. 2002
    ..65 (95% confidence interval: 0.46, 0.94) should be used because the adjusted odds ratio is invalid. Causal diagrams are used to encode qualitative a priori subject matter knowledge...
  23. ncbi request reprint The birth weight "paradox" uncovered?
    Sonia Hernandez-Diaz
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Epidemiol 164:1115-20. 2006
    ..An appropriate justification for conditioning on birth weight requires specifying 1) the causal question motivating this analytical approach and 2) the assumptions regarding the proposed underlying biologic mechanisms...
  24. pmc Hypertension in women of reproductive age in the United States: NHANES 1999-2008
    Brian T Bateman
    Division of Obstetric Anesthesia, Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    PLoS ONE 7:e36171. 2012
    ..To examine the epidemiology of hypertension in women of reproductive age...
  25. pmc Identification of phthalates in medications and dietary supplement formulations in the United States and Canada
    Katherine E Kelley
    Slone Epidemiology Center at Boston University, Boston, Massachusetts 02215, USA
    Environ Health Perspect 120:379-84. 2012
    ..Limited evidence suggests that particularly high exposure levels may result from orally ingested medicinal products containing phthalates as excipients (inactive ingredients)...
  26. ncbi request reprint Trends and predictors of folic acid awareness and periconceptional use in pregnant women
    Lolkje T W de Jong-van den Berg
    Slone Epidemiology Center, Boston University School of Public Health, Boston, Mass, USA
    Am J Obstet Gynecol 192:121-8. 2005
    ..The purpose of this study was to describe recent trends in folic acid awareness and use in the periconceptional period among pregnant women in relation to maternal sociodemographic and other relevant factors...
  27. pmc Case-only gene-environment interaction studies: when does association imply mechanistic interaction?
    Tyler J VanderWeele
    Harvard School of Public Health, Departments of Epidemiology and Biostatistics, 677 Huntington Avenue, Boston, MA 02115, USA
    Genet Epidemiol 34:327-34. 2010
    ..We furthermore show these tests for mechanistic interaction can be extended to scenarios in which the genetic and environmental factors are negatively associated in the population rather than independent...
  28. pmc Use of decongestants during pregnancy and the risk of birth defects
    Wai Ping Yau
    Department of Epidemiology, Harvard School of Public Health, Harvard University, Boston, MA, USA
    Am J Epidemiol 178:198-208. 2013
    ..Accumulating evidence supports associations between first-trimester use of specific oral and possibly intranasal decongestants and the risk of some infrequent specific birth defects. ..
  29. pmc Gestational hypertension in pregnancies supported by infertility treatments: role of infertility, treatments, and multiple gestations
    Sonia Hernandez-Diaz
    Slone Epidemiology Center at Boston University, Boston, Massachusetts 02215, USA
    Fertil Steril 88:438-45. 2007
    ..To investigate the association between infertility treatments and gestational hypertension and preeclampsia...
  30. pmc Cardioprotective aspirin users and their excess risk of upper gastrointestinal complications
    Sonia Hernandez-Diaz
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    BMC Med 4:22. 2006
    ....
  31. pmc Algorithms to estimate the beginning of pregnancy in administrative databases
    Andrea V Margulis
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Pharmacoepidemiol Drug Saf 22:16-24. 2013
    ..Therefore, we sought to develop and validate algorithms to estimate the gestational age at birth using information available in these databases...
  32. pmc Use of disease-modifying antirheumatic drugs during pregnancy and risk of preeclampsia
    Kristin Palmsten
    Harvard School of Public Health, Boston, Massachusetts, USA
    Arthritis Care Res (Hoboken) 64:1730-8. 2012
    ....
  33. pmc Safety of macrolides during pregnancy
    Kueiyu Joshua Lin
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Am J Obstet Gynecol 208:221.e1-8. 2013
    ..We sought to assess the association between maternal use of erythromycin and nonerythromycin macrolides and the risks of CHD and PS...
  34. ncbi request reprint Dietary folate and the risk of nonfatal myocardial infarction
    Sonia Hernandez-Diaz
    Slone Epidemiology Center, Boston University School of Public Health, Boston, MA 02215, USA
    Epidemiology 13:700-6. 2002
    ..Because folate intake can reduce homocysteine levels, we investigated the association between dietary folate intake and nonfatal myocardial infarction...
  35. ncbi request reprint Nonsteroidal anti-inflammatory drugs and risk of lung cancer
    Sonia Hernandez-Diaz
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Int J Cancer 120:1565-72. 2007
    ..34) for aspirin. In conclusion, prescription of non-aspirin NSAIDs for at least 1 year might be associated with a slightly reduced risk of lung cancer. Aspirin was not associated with a risk reduction, perhaps due to residual confounding...
  36. pmc Elevated risk of preeclampsia in pregnant women with depression: depression or antidepressants?
    Kristin Palmsten
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Am J Epidemiol 175:988-97. 2012
    ..24) for TCA monotherapy. Study results suggest that women who use antidepressants during pregnancy, especially SNRIs and TCAs, have an elevated risk of preeclampsia. These associations may reflect drug effects or more severe depression...
  37. pmc Selective serotonin reuptake inhibitor use and risk of gestational hypertension
    Sengwee Toh
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Psychiatry 166:320-8. 2009
    ..The purpose of this study was to assess the effects of treatment with selective serotonin reuptake inhibitors (SSRIs) on the risks of gestational hypertension and preeclampsia...
  38. ncbi request reprint Can folic acid protect against congenital heart defects in Down syndrome?
    Willemijn M Meijer
    Slone Epidemiology Center, Boston University, Boston, Massachusetts 02215 1201, USA
    Birth Defects Res A Clin Mol Teratol 76:714-7. 2006
    ..Our objectives were to investigate whether first-trimester FA use protects against heart anomalies among DS children...
  39. doi request reprint Patterns of medication use during pregnancy in rheumatoid arthritis
    Bindee Kuriya
    Harvard School of Public Health, Boston, Massachusetts, USA
    Arthritis Care Res (Hoboken) 63:721-8. 2011
    ..To characterize therapies prescribed during pregnancy to women with rheumatoid arthritis (RA)...
  40. doi request reprint The risk of congenital malformations associated with exposure to β-blockers early in pregnancy: a meta-analysis
    Mohammad Y Yakoob
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Hypertension 62:375-81. 2013
    ..Causality is difficult to interpret given the small number of heterogeneous studies and possibility of biases. Given the frequency of this exposure in pregnancy, further research is needed. ..
  41. doi request reprint Sensitivity and specificity of computerized algorithms to classify gestational periods in the absence of information on date of conception
    Sengwee Toh
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Epidemiol 167:633-40. 2008
    ..However, the sensitivity of this algorithm is lower for preterm deliveries, suggesting limited validity to assess drug safety for pregnancy outcomes associated with prematurity...
  42. pmc Medication use during pregnancy, with particular focus on prescription drugs: 1976-2008
    Allen A Mitchell
    Slone Epidemiology Center at Boston University, Boston, MA, USA
    Am J Obstet Gynecol 205:51.e1-8. 2011
    ..The objective of the study was to provide information on overall medication use throughout pregnancy, with particular focus on the first trimester and specific prescription medications...
  43. ncbi request reprint Risk factors for persistent pulmonary hypertension of the newborn
    Sonia Hernandez-Diaz
    Slone Epidemiology Center at Boston University, 1010 Commonwealth Ave, Boston, MA 02215, USA
    Pediatrics 120:e272-82. 2007
    ..We performed a case-control study to determine possible antenatal and perinatal predictors of persistent pulmonary hypertension of the newborn...
  44. ncbi request reprint A structural approach to selection bias
    Miguel A Hernán
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Epidemiology 15:615-25. 2004
    ..This classification also leads to a unified approach to adjust for selection bias...
  45. ncbi request reprint Non-steroidal antiinflammatory drugs and the risk of acute myocardial infarction
    Sonia Hernandez-Diaz
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Basic Clin Pharmacol Toxicol 98:266-74. 2006
    ..There was a suggestion of a small increased risk with ibuprofen. Also, data suggest a small reduced risk for naproxen present only in non-users of aspirin, mainly people free of clinically apparent vascular disease...
  46. pmc Nonsteroidal antiinflammatory drugs in late pregnancy and persistent pulmonary hypertension of the newborn
    Linda J Van Marter
    Boston Children s Hospital, Boston, Massachusetts 02115, USA
    Pediatrics 131:79-87. 2013
    ..This study was designed to test the hypothesis that risk for PPHN is increased after antenatal exposure to nonsteroidal antiinflammatory drugs (NSAIDs), with particular emphasis on late gestational exposures...
  47. ncbi request reprint Prescription of medications during pregnancy: accidents, compromises, and uncertainties
    Sonia Hernandez-Diaz
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Pharmacoepidemiol Drug Saf 15:613-7. 2006
  48. pmc Patterns of outpatient antihypertensive medication use during pregnancy in a Medicaid population
    Brian T Bateman
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Hypertension 60:913-20. 2012
    ..1%) in the third trimester. Antihypertensive use during pregnancy is relatively common and increasing. The wide range of agents used during pregnancy includes medications considered contraindicated during pregnancy...
  49. doi request reprint Acid suppressants reduce risk of gastrointestinal bleeding in patients on antithrombotic or anti-inflammatory therapy
    Kueiyu Joshua Lin
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    Gastroenterology 141:71-9. 2011
    ..We investigated the effect of different prevention strategies against upper gastrointestinal bleeding (UGIB) in the general population and in patients on antithrombotic or anti-inflammatory treatments...
  50. doi request reprint Systematic review of peptic ulcer disease incidence rates: do studies without validation provide reliable estimates?
    Kueiyu Joshua Lin
    Department of Epidemiology, Harvard School of Public Health, Boston, USA
    Pharmacoepidemiol Drug Saf 20:718-28. 2011
    ..Incidence rate (IR) estimates for peptic ulcer disease (PUD) vary widely among studies. We conducted a systematic review to quantify and examine the discrepancies...
  51. doi request reprint Fetal effects of anticonvulsant polytherapies: different risks from different drug combinations
    Lewis B Holmes
    North American AED Pregnancy Registry, Genetics Unit, MassGeneral Hospital for Children, Boston, MA 02114, USA
    Arch Neurol 68:1275-81. 2011
    ..To determine the frequency of malformations among infants born to women who had taken lamotrigine or carbamazepine as part of polytherapy during the first trimester of pregnancy...
  52. ncbi request reprint Nausea and vomiting in pregnancy: maternal characteristics and risk factors
    Carol Louik
    Slone Epidemiology Centre, Boston University, MA 02115, USA
    Paediatr Perinat Epidemiol 20:270-8. 2006
    ..Together with selected demographic characteristics that differentiate early- vs. late-onset NVP, these findings warrant further investigation...
  53. ncbi request reprint Psychomotor development in children and antenatal psychotropic and anti-epileptic drugs
    Sonia Hernandez-Diaz
    Slone Epidemiology Center, Boston University, Boston, MA, USA
    Eur J Epidemiol 18:743-4. 2003
  54. ncbi request reprint Tetanus vaccination and risk of multiple sclerosis: a systematic review
    Miguel A Hernán
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Neurology 67:212-5. 2006
    ..To conduct a systematic review on the association between tetanus vaccination and the risk of multiple sclerosis (MS)...
  55. doi request reprint Risk of complications after a peptic ulcer diagnosis: effectiveness of proton pump inhibitors
    Sonia Hernandez-Diaz
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Dig Dis Sci 58:1653-62. 2013
    ..e., a clear indication. To minimize selection bias we mimicked an intention to treat approach by assessing the effect of PPI prescription after PU diagnosis...
  56. pmc Risk of ischemic cerebrovascular and coronary events in adult users of anticonvulsant medications in routine care settings
    Elisabetta Patorno
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA
    J Am Heart Assoc 2:e000208. 2013
    ....
  57. pmc Coronary heart disease in postmenopausal recipients of estrogen plus progestin therapy: does the increased risk ever disappear? A randomized trial
    Sengwee Toh
    Department of Population Medicine, Harvard Medical School Harvard Pilgrim Health Care Institute, 133 Brookline Avenue, 6th Floor, Boston, MA 02215, USA
    Ann Intern Med 152:211-7. 2010
    ..Estrogen plus progestin therapy increases the risk for coronary heart disease (CHD) in postmenopausal women. However, this increased risk might be limited to the first years of use and to women who start therapy late in menopause...
  58. pmc From causal diagrams to birth weight-specific curves of infant mortality
    Sonia Hernandez-Diaz
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Eur J Epidemiol 23:163-6. 2008
    ..Taken together, these two approaches can facilitate discussion of underlying biological mechanisms...
  59. ncbi request reprint Use of over-the-counter medications during pregnancy
    Martha M Werler
    Slone Epidemiology Center at Boston University, Boston, MA, USA
    Am J Obstet Gynecol 193:771-7. 2005
    ..We describe the patterns of over-the-counter medication use among pregnant women...
  60. pmc Antibiotics and oral contraceptive failure - a case-crossover study
    Sengwee Toh
    Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA 02215, USA
    Contraception 83:418-25. 2011
    ..Evidence on the association between antibiotic use and combined oral contraceptive (COC) failure is controversial. We examined the effect of concomitant antibiotic treatment on the risk of breakthrough pregnancy among COC users...
  61. pmc Risk of pre-eclampsia in first and subsequent pregnancies: prospective cohort study
    Sonia Hernandez-Diaz
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Ave, Boston, MA 02115, USA
    BMJ 338:b2255. 2009
    ..To investigate whether pre-eclampsia is more common in first pregnancies solely because fewer affected women, who presumably have a higher risk of recurrence, go on to have subsequent pregnancies...
  62. doi request reprint Positive predictive value of computerized medical records for uncomplicated and complicated upper gastrointestinal ulcer
    Andrea V Margulis
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Pharmacoepidemiol Drug Saf 18:900-9. 2009
    ..We assessed the PPV of diagnosis codes in THIN, a primary-care medical-record database, to ascertain individuals with uncomplicated PU, and to identify UGIC and Helicobacter pylori infection status (HPIS) among these patients...
  63. ncbi request reprint Use of antidepressants and risk of lung cancer
    Sengwee Toh
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Cancer Causes Control 18:1055-64. 2007
    ..To evaluate the effect of antidepressant use on lung cancer risk...
  64. ncbi request reprint Incidence of serious upper gastrointestinal bleeding/perforation in the general population: review of epidemiologic studies
    Sonia Hernandez-Diaz
    Slone Epidemiology Unit, Boston University School of Public Health, Boston, MA, USA
    J Clin Epidemiol 55:157-63. 2002
    ..Overall, the incidence rate of serious upper gastrointestinal complications was in the order of 1 per 1,000 person-years among nonusers of prescription NSAIDs...
  65. pmc Food insufficiency is a risk factor for suboptimal antiretroviral therapy adherence among HIV-infected adults in urban Peru
    Molly F Franke
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    AIDS Behav 15:1483-9. 2011
    ..R. per 5 point increase:0.91; C.I.:[0.85, 0.98]) and good baseline adherence self-efficacy (O.R.:0.25; C.I.:[0.09, 0.69]). Interventions that ensure food security for HIV-infected individuals may help sustain high levels of adherence...
  66. ncbi request reprint Statins and fracture risk. A systematic review
    Sengwee Toh
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Pharmacoepidemiol Drug Saf 16:627-40. 2007
    ..To summarize current evidence on statin use and fracture risk and to explore potential sources of heterogeneity among study results...
  67. doi request reprint Antibiotic use and the risk of lung cancer
    Hui Zhang
    Department Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 17:1308-15. 2008
    ..Current evidence is insufficient to support or refute a carcinogenic effect of antibiotics...
  68. doi request reprint Prevalence, trends, and outcomes of chronic hypertension: a nationwide sample of delivery admissions
    Brian T Bateman
    Division of Obstetric Anesthesia, Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Am J Obstet Gynecol 206:134.e1-8. 2012
    ..We sought to define the prevalence, trends, and outcomes of primary and secondary chronic hypertension in a population-based sample of deliveries...
  69. pmc Beyond the intention-to-treat in comparative effectiveness research
    Miguel A Hernán
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Clin Trials 9:48-55. 2012
    ..The intention-to-treat comparison is the primary, if not the only, analytic approach of many randomized clinical trials...
  70. ncbi request reprint Pharmacoepidemiology and rheumatic disorders
    K Arnold Chan
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Rheum Dis Clin North Am 30:835-50, vii. 2004
    ....
  71. pmc Medications as a potential source of exposure to phthalates in the U.S. population
    Sonia Hernandez-Diaz
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Environ Health Perspect 117:185-9. 2009
    ..Underappreciated sources of exposure include phthalates in the polymers coating some oral medications...