A M Healy

Summary

Affiliation: Boston University
Country: USA

Publications

  1. ncbi Intravascular coagulation activation in a murine model of thrombomodulin deficiency: effects of lesion size, age, and hypoxia on fibrin deposition
    A M Healy
    The Pulmonary Center, Boston University School of Medicine the Department of Pathology, Harvard Medical School, Boston, MA, USA
    Blood 92:4188-97. 1998
  2. ncbi VEGF is deposited in the subepithelial matrix at the leading edge of branching airways and stimulates neovascularization in the murine embryonic lung
    A M Healy
    The Pulmonary Center, Boston University School of Medicine, Boston Massachusetts 02118, USA
    Dev Dyn 219:341-52. 2000
  3. ncbi Gas 6 promotes Axl-mediated survival in pulmonary endothelial cells
    A M Healy
    Pulmonary Center, Boston University School of Medicine, 715 Albany Street, Boston, MA 02118, USA
    Am J Physiol Lung Cell Mol Physiol 280:L1273-81. 2001
  4. ncbi A targeted point mutation in thrombomodulin generates viable mice with a prethrombotic state
    H Weiler-Guettler
    Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    J Clin Invest 101:1983-91. 1998
  5. ncbi Absence of the blood-clotting regulator thrombomodulin causes embryonic lethality in mice before development of a functional cardiovascular system
    A M Healy
    Department of Biology, Massachusetts Institute of Technology, Cambridge 02139
    Proc Natl Acad Sci U S A 92:850-4. 1995
  6. ncbi Identification of a bipartite nuclear localization sequence necessary for nuclear import of 5-lipoxygenase
    A M Healy
    Division of Pulmonary Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan 48109 0642, USA
    J Biol Chem 274:29812-8. 1999

Collaborators

Detail Information

Publications6

  1. ncbi Intravascular coagulation activation in a murine model of thrombomodulin deficiency: effects of lesion size, age, and hypoxia on fibrin deposition
    A M Healy
    The Pulmonary Center, Boston University School of Medicine the Department of Pathology, Harvard Medical School, Boston, MA, USA
    Blood 92:4188-97. 1998
    ..Our findings show that TM chimerism results in spontaneous, intravascular fibrin deposition that is dependent on age and the magnitude of the TM deficiency...
  2. ncbi VEGF is deposited in the subepithelial matrix at the leading edge of branching airways and stimulates neovascularization in the murine embryonic lung
    A M Healy
    The Pulmonary Center, Boston University School of Medicine, Boston Massachusetts 02118, USA
    Dev Dyn 219:341-52. 2000
    ..The restricted temporal and spatial expression of VEGF suggests that matrix-associated VEGF links airway branching with blood vessel formation by stimulating neovascularization at the leading edge of branching airways...
  3. ncbi Gas 6 promotes Axl-mediated survival in pulmonary endothelial cells
    A M Healy
    Pulmonary Center, Boston University School of Medicine, 715 Albany Street, Boston, MA 02118, USA
    Am J Physiol Lung Cell Mol Physiol 280:L1273-81. 2001
    ..Collectively, the data demonstrate antiapoptotic activities for Gas 6 in HPAEC and suggest that Gas 6 signaling may be relevant to endothelial cell survival in the quiescent environment of the vessel wall...
  4. ncbi A targeted point mutation in thrombomodulin generates viable mice with a prethrombotic state
    H Weiler-Guettler
    Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    J Clin Invest 101:1983-91. 1998
    ..The thrombomodulin-deficient animals provide a murine model to examine known or identify unknown genetic and environmental factors that lead to the development of thrombosis...
  5. ncbi Absence of the blood-clotting regulator thrombomodulin causes embryonic lethality in mice before development of a functional cardiovascular system
    A M Healy
    Department of Biology, Massachusetts Institute of Technology, Cambridge 02139
    Proc Natl Acad Sci U S A 92:850-4. 1995
    ....
  6. ncbi Identification of a bipartite nuclear localization sequence necessary for nuclear import of 5-lipoxygenase
    A M Healy
    Division of Pulmonary Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan 48109 0642, USA
    J Biol Chem 274:29812-8. 1999
    ..As nuclear import of 5-lipoxygenase may regulate leukotriene production, natural or induced mutations in this bipartite nuclear localization sequence may also be important in affecting leukotriene synthesis...