H C Guo

Summary

Affiliation: Boston University
Country: USA

Publications

  1. ncbi request reprint Crystal structures of Flavobacterium glycosylasparaginase. An N-terminal nucleophile hydrolase activated by intramolecular proteolysis
    H C Guo
    Department of Biophysics, Boston University School of Medicine, Boston, Massachusetts 02118 2526, USA
    J Biol Chem 273:20205-12. 1998
  2. ncbi request reprint Structural insights into the mechanism of intramolecular proteolysis
    Q Xu
    Department of Biophysics, Boston University School of Medicine, Massachusetts 02118 2526, USA
    Cell 98:651-61. 1999
  3. ncbi request reprint Different length peptides bind to HLA-Aw68 similarly at their ends but bulge out in the middle
    H C Guo
    Department of Biochemistry and Molecular Biology, Harvard University, Cambridge, Massachusetts 02138
    Nature 360:364-6. 1992
  4. ncbi request reprint Atomic structure of a human MHC molecule presenting an influenza virus peptide
    M L Silver
    Department of Biochemistry and Molecular Biology, Harvard University, Cambridge, Massachusetts 02138
    Nature 360:367-9. 1992

Collaborators

  • Q Xu
  • M L Silver
  • D C Wiley
  • J L Strominger

Detail Information

Publications4

  1. ncbi request reprint Crystal structures of Flavobacterium glycosylasparaginase. An N-terminal nucleophile hydrolase activated by intramolecular proteolysis
    H C Guo
    Department of Biophysics, Boston University School of Medicine, Boston, Massachusetts 02118 2526, USA
    J Biol Chem 273:20205-12. 1998
    ..The presence of the heterotetrameric structure in the crystals is significant because dimerization of precursors has been suggested in the human enzyme to be a prerequisite to trigger autoproteolysis...
  2. ncbi request reprint Structural insights into the mechanism of intramolecular proteolysis
    Q Xu
    Department of Biophysics, Boston University School of Medicine, Massachusetts 02118 2526, USA
    Cell 98:651-61. 1999
    ....
  3. ncbi request reprint Different length peptides bind to HLA-Aw68 similarly at their ends but bulge out in the middle
    H C Guo
    Department of Biochemistry and Molecular Biology, Harvard University, Cambridge, Massachusetts 02138
    Nature 360:364-6. 1992
    ....
  4. ncbi request reprint Atomic structure of a human MHC molecule presenting an influenza virus peptide
    M L Silver
    Department of Biochemistry and Molecular Biology, Harvard University, Cambridge, Massachusetts 02138
    Nature 360:367-9. 1992
    ..The structure defines in atomic detail the antigenic surface constructed of major histocompatibility complex and viral peptide atoms that is recognized by T-cell receptors...