Suryaram Gummuluru

Summary

Affiliation: Boston University
Country: USA

Publications

  1. pmc Glycosphingolipid-functionalized nanoparticles recapitulate CD169-dependent HIV-1 uptake and trafficking in dendritic cells
    Xinwei Yu
    Department of Chemistry and The Photonics Center, Boston University, Boston, Massachusetts 02215, USA
    Nat Commun 5:4136. 2014
  2. pmc Interferon-inducible mechanism of dendritic cell-mediated HIV-1 dissemination is dependent on Siglec-1/CD169
    Wendy Blay Puryear
    Department of Microbiology, Boston University School of Medicine, Boston, Massachusetts, United States of America
    PLoS Pathog 9:e1003291. 2013
  3. pmc Binding of human immunodeficiency virus type 1 to immature dendritic cells can occur independently of DC-SIGN and mannose binding C-type lectin receptors via a cholesterol-dependent pathway
    Suryaram Gummuluru
    Division of Human Biology, Fred Hutchinson Cancer Research Center Seattle Biomedical Research Institute, Seattle, Washington 98109, USA
    J Virol 77:12865-74. 2003
  4. pmc HIV-1 incorporation of host-cell-derived glycosphingolipid GM3 allows for capture by mature dendritic cells
    Wendy Blay Puryear
    Department of Microbiology, Boston University School of Medicine, Boston, MA 02118, USA
    Proc Natl Acad Sci U S A 109:7475-80. 2012
  5. pmc Dendritic cell-mediated viral transfer to T cells is required for human immunodeficiency virus type 1 persistence in the face of rapid cell turnover
    Suryaram Gummuluru
    Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    J Virol 76:10692-701. 2002
  6. pmc Virus particle release from glycosphingolipid-enriched microdomains is essential for dendritic cell-mediated capture and transfer of HIV-1 and henipavirus
    Hisashi Akiyama
    Department of Microbiology, Boston University School of Medicine, Boston, Massachusetts, USA
    J Virol 88:8813-25. 2014
  7. pmc PPARgamma and LXR signaling inhibit dendritic cell-mediated HIV-1 capture and trans-infection
    Timothy M Hanley
    Department of Microbiology, Boston University School of Medicine, Boston, Massachusetts, United States of America
    PLoS Pathog 6:e1000981. 2010
  8. pmc Role of glycosphingolipids in dendritic cell-mediated HIV-1 trans-infection
    Wendy Blay Puryear
    Department of Microbiology, Boston University School of Medicine, Boston, MA, USA
    Adv Exp Med Biol 762:131-53. 2013
  9. pmc Interleukin 2-inducible T cell kinase (ITK) facilitates efficient egress of HIV-1 by coordinating Gag distribution and actin organization
    Gillian M Schiralli Lester
    Department of Medicine, Section of Infectious Diseases, Boston University School of Medicine, Boston, MA 02118, United States
    Virology 436:235-43. 2013
  10. ncbi Advances in HIV molecular biology
    Suryaram Gummuluru
    Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle WA 98109, USA
    AIDS 16:S17-23. 2002

Collaborators

  • Juswinder Singh
  • Leonidas Stamatatos
  • Vineet N Kewalramani
  • Wendy Blay Puryear
  • Hisashi Akiyama
  • Xinwei Yu
  • Steven C Hatch
  • Nora Guadalupe P Ramirez
  • Gillian M Schiralli Lester
  • Nora P Ramirez
  • Björn M Reinhard
  • Jacob Archer
  • Timothy M Hanley
  • Rebecca D Wiley
  • Björn M Reinhard
  • Amin Feizpour
  • Linxi Wu
  • Hiren V Patel
  • Caitlin Miller
  • Fangda Xu
  • Andrew J Henderson
  • Erica Evans
  • Suzanne D Geer
  • Gregory A Viglianti

Detail Information

Publications12

  1. pmc Glycosphingolipid-functionalized nanoparticles recapitulate CD169-dependent HIV-1 uptake and trafficking in dendritic cells
    Xinwei Yu
    Department of Chemistry and The Photonics Center, Boston University, Boston, Massachusetts 02215, USA
    Nat Commun 5:4136. 2014
    ..They also indicate that plasmonic AVNs offer improved features over liposome-based systems and represent a versatile tool for probing specific virus-cell interactions. ..
  2. pmc Interferon-inducible mechanism of dendritic cell-mediated HIV-1 dissemination is dependent on Siglec-1/CD169
    Wendy Blay Puryear
    Department of Microbiology, Boston University School of Medicine, Boston, Massachusetts, United States of America
    PLoS Pathog 9:e1003291. 2013
    ..Together, these findings describe a novel mechanism of pathogen parasitization of host encoded cellular recognition machinery (GM3--CD169 interaction) for DC-dependent HIV dissemination...
  3. pmc Binding of human immunodeficiency virus type 1 to immature dendritic cells can occur independently of DC-SIGN and mannose binding C-type lectin receptors via a cholesterol-dependent pathway
    Suryaram Gummuluru
    Division of Human Biology, Fred Hutchinson Cancer Research Center Seattle Biomedical Research Institute, Seattle, Washington 98109, USA
    J Virol 77:12865-74. 2003
    ..We propose that pathways to HIV-1 attachment and uptake in DC exhibit functional redundancy; that is, they are made up of multiple independent activities that can, at least in part, compensate for one another...
  4. pmc HIV-1 incorporation of host-cell-derived glycosphingolipid GM3 allows for capture by mature dendritic cells
    Wendy Blay Puryear
    Department of Microbiology, Boston University School of Medicine, Boston, MA 02118, USA
    Proc Natl Acad Sci U S A 109:7475-80. 2012
    ....
  5. pmc Dendritic cell-mediated viral transfer to T cells is required for human immunodeficiency virus type 1 persistence in the face of rapid cell turnover
    Suryaram Gummuluru
    Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    J Virol 76:10692-701. 2002
    ..These results suggest that dendritic cell-mediated transmission of HIV-1 enables virus replication under conditions of rapid cell turnover in vivo...
  6. pmc Virus particle release from glycosphingolipid-enriched microdomains is essential for dendritic cell-mediated capture and transfer of HIV-1 and henipavirus
    Hisashi Akiyama
    Department of Microbiology, Boston University School of Medicine, Boston, Massachusetts, USA
    J Virol 88:8813-25. 2014
    ....
  7. pmc PPARgamma and LXR signaling inhibit dendritic cell-mediated HIV-1 capture and trans-infection
    Timothy M Hanley
    Department of Microbiology, Boston University School of Medicine, Boston, Massachusetts, United States of America
    PLoS Pathog 6:e1000981. 2010
    ..The ability of NR ligands to repress DC mediated trans-infection, inflammation, and DC migration underscores their potential therapeutic value in inhibiting HIV-1 mucosal transmission...
  8. pmc Role of glycosphingolipids in dendritic cell-mediated HIV-1 trans-infection
    Wendy Blay Puryear
    Department of Microbiology, Boston University School of Medicine, Boston, MA, USA
    Adv Exp Med Biol 762:131-53. 2013
    ....
  9. pmc Interleukin 2-inducible T cell kinase (ITK) facilitates efficient egress of HIV-1 by coordinating Gag distribution and actin organization
    Gillian M Schiralli Lester
    Department of Medicine, Section of Infectious Diseases, Boston University School of Medicine, Boston, MA 02118, United States
    Virology 436:235-43. 2013
    ..These data provide insight as to how ITK influences HIV-1 replication and suggest that targeting host factors that regulate HIV-1 egress provides an innovative strategy for controlling HIV infection...
  10. ncbi Advances in HIV molecular biology
    Suryaram Gummuluru
    Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle WA 98109, USA
    AIDS 16:S17-23. 2002
  11. pmc Glycosphingolipid composition of human immunodeficiency virus type 1 (HIV-1) particles is a crucial determinant for dendritic cell-mediated HIV-1 trans-infection
    Steven C Hatch
    Department of Microbiology, Boston University School of Medicine, 72 E Concord St, R509, Boston, MA 02118, USA
    J Virol 83:3496-506. 2009
    ....
  12. pmc Immature dendritic cell-derived exosomes can mediate HIV-1 trans infection
    Rebecca D Wiley
    Department of Microbiology, Boston University School of Medicine, Boston, MA 02118, USA
    Proc Natl Acad Sci U S A 103:738-43. 2006
    ....