Research Topics
| A GuermaziSummaryAffiliation: Boston University Country: USA Publications
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Publications
MRI-based semiquantitative scoring of joint pathology in osteoarthritisAli Guermazi
Department of Radiology, Boston University School of Medicine, 820 Harrison Avenue, FGH Building 3rd Floor, Boston, MA 02118, USA
Nat Rev Rheumatol 9:236-51. 2013..Although these new scoring systems offer theoretical advantages over pre-existing systems, whether they offer actual superiority with regard to reliability, responsiveness and validity remains to be seen...
Imaging of osteoarthritisAli Guermazi
Department of Radiology, Boston University School of Medicine, 820 Harrison Avenue, FGH Building 3rd Floor, Boston, MA 02118, USA Electronic address
Rheum Dis Clin North Am 39:67-105. 2013..The emphasis throughout is on OA of the knee. This article emphasizes research developments and literature evidence published since 2008...
Prevalence of abnormalities in knees detected by MRI in adults without knee osteoarthritis: population based observational study (Framingham Osteoarthritis Study)Ali Guermazi
Department of Radiology, Boston University School of Medicine, FGH Building, 820 Harrison Avenue, Boston, MA 02118, USA
BMJ 345:e5339. 2012..To examine use of magnetic resonance imaging (MRI) of knees with no radiographic evidence of osteoarthritis to determine the prevalence of structural lesions associated with osteoarthritis and their relation to age, sex, and obesity...
Why radiography should no longer be considered a surrogate outcome measure for longitudinal assessment of cartilage in knee osteoarthritisAli Guermazi
Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine, 820 Harrison Avenue, FGH Building, 3rd Floor, Boston, MA 02118, USA
Arthritis Res Ther 13:247. 2011..Detection of joint space narrowing on radiography seems outdated now that it is possible to directly visualize morphologic and pre-morphologic changes of cartilage by using conventional as well as complex MRI techniques...
Semiquantitative assessment of subchondral bone marrow edema-like lesions and subchondral cysts of the knee at 3T MRI: a comparison between intermediate-weighted fat-suppressed spin echo and Dual Echo Steady State sequencesDaichi Hayashi
Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine, Boston, MA 02118, USA
BMC Musculoskelet Disord 12:198. 2011....
Different thresholds for detecting osteophytes and joint space narrowing exist between the site investigators and the centralized reader in a multicenter knee osteoarthritis study--data from the Osteoarthritis InitiativeAli Guermazi
Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine, 820 Harrison Avenue, FGH Building 3rd Floor, Boston, MA 02118, USA
Skeletal Radiol 41:179-86. 2012..To evaluate how the reading of knee radiographs by site investigators differs from that by an expert musculoskeletal radiologist who trained and validated them in a multicenter knee osteoarthritis (OA) study...
Imaging in osteoarthritisAli Guermazi
Department of Radiology, Boston University School of Medicine, 820 Harrison Avenue, FGH Building, Third Floor, Boston, MA 02118, USA
Rheum Dis Clin North Am 34:645-87. 2008..The other modalities discussed in this article are valuable additional techniques indicated on a case-by-case basis...
Cyst-like lesions of the knee joint and their relation to incident knee pain and development of radiographic osteoarthritis: the MOST studyA Guermazi
Department of Radiology, Boston University School of Medicine, 820 Harrison Avenue, Boston, MA 02118, USA
Osteoarthritis Cartilage 18:1386-92. 2010..To determine whether intra- and periarticular cyst-like lesions of the knee are associated with incident knee pain and incident radiographic knee osteoarthritis (OA)...
Osteoarthritis: current role of imagingAli Guermazi
Department of Radiology, Boston University School of Medicine, 820 Harrison Avenue, FGH Building, Third Floor, Boston, MA 02118, USA
Med Clin North Am 93:101-26, xi. 2009..This article focuses on radiography and MRI, with insight into other modalities, such as ultrasound, scintigraphy, and CT. Their role in OA diagnosis, follow-up, and research is discussed...
Plain radiography and magnetic resonance imaging diagnostics in osteoarthritis: validated staging and scoringAli Guermazi
Section of Musculoskeletal Imaging, Department of Radiology, Boston Medical Center, FGH Building, 820 Harrison Avenue, Boston, MA 02118, USA
J Bone Joint Surg Am 91:54-62. 2009....
Assessment of synovitis with contrast-enhanced MRI using a whole-joint semiquantitative scoring system in people with, or at high risk of, knee osteoarthritis: the MOST studyAli Guermazi
Quantitative Imaging Center QIC, Department of Radiology, Boston University School of Medicine, 820 Harrison Avenue, FGH Building, 3rd Floor, Boston, MA 02118, USA
Ann Rheum Dis 70:805-11. 2011..To introduce a comprehensive and reliable scoring system for the assessment of whole-knee joint synovitis based on contrast-enhanced (CE) MRI...
Imaging of osteoarthritis: update from a radiological perspectiveAli Guermazi
Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
Curr Opin Rheumatol 23:484-91. 2011..To assist investigators in choosing the appropriate imaging technique for a particular goal of a study, this review describes, from a radiological point of view, key studies that were published between May 2010 and May 2011...
Change in MRI-detected subchondral bone marrow lesions is associated with cartilage loss: the MOST Study. A longitudinal multicentre study of knee osteoarthritisF W Roemer
Department of Radiology, Boston University Medical Center, FGH Building, 3 Floor, 820 Harrison Ave, Boston, MA 02118, USA
Ann Rheum Dis 68:1461-5. 2009..Additionally, to examine the association of change in BMLs from baseline to 30-month follow-up with the risk of cartilage loss in the same subregion at follow-up...
Subchondral bone marrow lesions are highly associated with, and predict subchondral bone attrition longitudinally: the MOST studyF W Roemer
Quantitative Imaging Center QIC, Department of Radiology, Boston University Medical Center, Boston, MA 02118, USA
Osteoarthritis Cartilage 18:47-53. 2010..The aim of this study was to evaluate the cross-sectional and longitudinal association of BMLs with SBA in the same subregion of the knee...
The association of bone attrition with knee pain and other MRI features of osteoarthritisG Hernández-Molina
Clinical Epidemiology Reseach and Training Unit and the Department of Radiology, Boston University School of Medicine, Boston, MA, USA
Ann Rheum Dis 67:43-7. 2008....
Predictive validity of within-grade scoring of longitudinal changes of MRI-based cartilage morphology and bone marrow lesion assessment in the tibio-femoral joint--the MOST studyF W Roemer
Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine, Boston, MA 02118, USA
Osteoarthritis Cartilage 20:1391-8. 2012..The aim of this study was to examine the validity provided by within-grade scoring...
Association between patella alta and the prevalence and worsening of structural features of patellofemoral joint osteoarthritis: the multicenter osteoarthritis studyJ J Stefanik
Boston University School of Medicine, Boston, Massachusetts 02118, USA
Arthritis Care Res (Hoboken) 62:1258-65. 2010..To examine the relationship between patella alta and the prevalence and worsening at followup of structural features of patellofemoral joint (PFJ) osteoarthritis (OA) on magnetic resonance imaging (MRI)...
Does cartilage volume or thickness distinguish knees with and without mild radiographic osteoarthritis? The Framingham StudyS Reichenbach
Clinical Epidemiology Unit, Boston University Medical Center, Boston, Massachusetts, USA
Ann Rheum Dis 69:143-9. 2010..To examine whether the quantity of cartilage or semiquantitative scores actually differ in knees with mild radiographic osteoarthritis compared with knees without osteoarthritis...
Effect of meniscal damage on the development of frequent knee pain, aching, or stiffnessM Englund
Clinical Epidemiology Branch and Training Unit, Boston University School of Medicine, 650 Albany Street, Boston, MA 02118, USA
Arthritis Rheum 56:4048-54. 2007..To evaluate the effect of meniscal damage on the development of frequent knee pain, aching, or stiffness in middle-aged and older adults...
Change in joint space width: hyaline articular cartilage loss or alteration in meniscus?D J Hunter
Boston University Clinical Epidemiology Research and Training Unit, Arthritis Center, and Boston Medical Center, Boston, Massachusetts 02118, USA
Arthritis Rheum 54:2488-95. 2006..To explore the relative contribution of hyaline cartilage morphologic features and the meniscus to the radiographic joint space...
Contrast-enhanced MRI of subchondral cysts in patients with or at risk for knee osteoarthritis: the MOST studyM D Crema
Department of Radiology, Boston University School of Medicine, 820 Harrison Ave, FGH Building, 3rd Floor, Boston, MA 02118, USA
Eur J Radiol 75:e92-6. 2010....
Prevalence of bone attrition on knee radiographs and MRI in a community-based cohortS Reichenbach
Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA 02118, United States
Osteoarthritis Cartilage 16:1005-10. 2008....
Knee malalignment is associated with an increased risk for incident and enlarging bone marrow lesions in the more loaded compartments: the MOST studyD Hayashi
Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine, Boston, MA 02118, USA
Osteoarthritis Cartilage 20:1227-33. 2012..To examine the relationship of knee malalignment with occurrence of incident and enlarging bone marrow lesions (BMLs) and regression of BMLs...
A comparison of dedicated 1.0 T extremity MRI vs large-bore 1.5 T MRI for semiquantitative whole organ assessment of osteoarthritis: the MOST studyF W Roemer
Quantitative Imaging Center QIC, Department of Radiology, Boston University Medical Center, Boston, MA 02118, USA
Osteoarthritis Cartilage 18:168-74. 2010..The aim of this study was to compare semi-quantitative (SQ) scoring on a 1.0 T system using 1.5 T MRI as the standard of reference...
Cartilage loss occurs in the same subregions as subchondral bone attrition: a within-knee subregion-matched approach from the Multicenter Osteoarthritis StudyT Neogi
Boston University School of Medicine, 650 Albany Street, Clinical Epidemiology Unit, Suite X 200, Boston, MA 02118, USA
Arthritis Rheum 61:1539-44. 2009..We therefore evaluated whether SBA was associated with cartilage loss within the same subregion of the knee...
Relation of synovitis to knee pain using contrast-enhanced MRIsK Baker
Clinical Epidemiology Research and Training Unit, Boston University Medical Center, 650 Albany Street, Suite X200, Boston, MA 02118, USA
Ann Rheum Dis 69:1779-83. 2010..It has been suggested that synovitis causes joint pain. On non-contrast-enhanced MRIs synovial thickening cannot be assessed and on these images synovitis has been inconsistently associated with pain...
The association of meniscal damage with joint effusion in persons without radiographic osteoarthritis: the Framingham and MOST osteoarthritis studiesF W Roemer
Quantitative Imaging Center QIC, Department of Radiology, Boston University Medical Center, Boston, MA 02118, USA
Osteoarthritis Cartilage 17:748-53. 2009..To assess the cross-sectional association between meniscal status and joint effusion on magnetic resonance imaging (MRI) in knees without radiographic osteoarthritis (OA)...
The association of prevalent medial meniscal pathology with cartilage loss in the medial tibiofemoral compartment over a 2-year periodM D Crema
Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine, Boston, MA 02118, USA
Osteoarthritis Cartilage 18:336-43. 2010..To investigate the association of different types of magnetic resonance imaging (MRI)-detected medial meniscal pathology with subregional cartilage loss in the medial tibiofemoral compartment...
Peripatellar synovitis: comparison between non-contrast-enhanced and contrast-enhanced MRI and association with pain. The MOST studyM D Crema
Department of Radiology, Quantitative Imaging Center, Boston University School of Medicine, Boston, MA, USA Department of Radiology, Hospital do Coração HCor, and Teleimagem, Sao Paulo, Brazil Electronic address
Osteoarthritis Cartilage 21:413-8. 2013....
Meniscal damage associated with increased local subchondral bone mineral density: a Framingham studyG H Lo
Tufts New England Medical Center, Boston, MA 02111, USA
Osteoarthritis Cartilage 16:261-7. 2008..We hypothesized that knees with higher M:L BMD, consistent with increased medial subchondral BMD, would be associated with medial meniscal damage, and lower ratios with lateral meniscal damage...
Prevalent cartilage damage and cartilage loss over time are associated with incident bone marrow lesions in the tibiofemoral compartments: the MOST studyM D Crema
Department of Radiology, Quantitative Imaging Center, Boston University School of Medicine, Boston, MA, USA Department of Radiology, Hospital do Coração HCor and Teleimagem, Sao Paulo, Brazil Electronic address
Osteoarthritis Cartilage 21:306-13. 2013..To assess the association of prevalent cartilage damage and cartilage loss over time with incident bone marrow lesions (BMLs) in the same subregion of the tibiofemoral compartments as detected on magnetic resonance imaging (MRI)...
The association of meniscal pathologic changes with cartilage loss in symptomatic knee osteoarthritisD J Hunter
Boston Medical Center, Boston, Massachusetts, USA
Arthritis Rheum 54:795-801. 2006..To explore the role of meniscal tears and meniscal malposition as risk factors for subsequent cartilage loss in subjects with symptomatic osteoarthritis (OA)...
Comparison of BLOKS and WORMS scoring systems part II. Longitudinal assessment of knee MRIs for osteoarthritis and suggested approach based on their performance: data from the Osteoarthritis InitiativeD T Felson
Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA 02118, USA
Osteoarthritis Cartilage 18:1402-7. 2010....
Imaging in osteoarthritis: what have we learned and where are we going?D Hayashi
Department of Radiology, Boston University School of Medicine, Boston, MA, USA
Minerva Med 102:15-32. 2011....
MRI-detected subchondral bone marrow signal alterations of the knee joint: terminology, imaging appearance, relevance and radiological differential diagnosisF W Roemer
Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine, Boston, MA, USA
Osteoarthritis Cartilage 17:1115-31. 2009..To discuss terminology, radiological differential diagnoses and significance of magnetic resonance imaging (MRI)-detected subchondral bone marrow lesions (BMLs) of the knee joint...
The relation of femoral notch stenosis to ACL tears in persons with knee osteoarthritisV Stein
Division of Research, New England Baptist Hospital, Boston, MA 02120, USA
Osteoarthritis Cartilage 18:192-9. 2010..The purpose of this study was to test if persons with knee osteoarthritis (OA) and ACL tears have smaller NWI independent of prior joint injury and osteophyte volume...
Bone marrow lesions in the knee are associated with increased local bone densityGrace H Lo
Boston University, Boston, Massachusetts, USA
Arthritis Rheum 52:2814-21. 2005..Therefore, we hypothesized that a higher M:L BMD ratio would be associated with medial bone marrow lesions, and that lower ratios would be associated with lateral bone marrow lesions...
Central bone marrow lesions in symptomatic knee osteoarthritis and their relationship to anterior cruciate ligament tears and cartilage lossGabriela Hernández-Molina
Boston University School of Medicine, Boston, Massachusetts 02118, USA
Arthritis Rheum 58:130-6. 2008....
The association of magnetic resonance imaging (MRI)-detected structural pathology of the knee with crepitus in a population-based cohort with knee pain: the MoDEKO studyM D Crema
Department of Radiology, Boston University School of Medicine, 820 Harrison Avenue, FGH Building, Third Floor, Boston, MA 02118, USA
Osteoarthritis Cartilage 19:1429-32. 2011..In the selected whole-knee model, only meniscal tears were associated with an increased risk for general crepitus. Thus, it seems that crepitus may be associated with pathology in several internal structures...
Hip Osteoarthritis MRI Scoring System (HOAMS): reliability and associations with radiographic and clinical findingsF W Roemer
Quantitative Imaging Center, Department of Radiology, Boston University Medical Center, 820 Harrison Avenue, Boston, MA 02118, USA
Osteoarthritis Cartilage 19:946-62. 2011..To develop a semiquantitative MRI-based scoring system (HOAMS) of hip osteoarthritis (OA) and test its reliability and validity...
The reliability of a new scoring system for knee osteoarthritis MRI and the validity of bone marrow lesion assessment: BLOKS (Boston Leeds Osteoarthritis Knee Score)D J Hunter
Boston University Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, 715 Albany St, Boston, MA 02118, USA
Ann Rheum Dis 67:206-11. 2008..The aim of this work was to assess the reliability of a novel MRI scoring system for evaluating OA of the knee and explore the validity of the bone marrow lesion (BML) scoring component of this new tool...
Tibiofemoral joint osteoarthritis: risk factors for MR-depicted fast cartilage loss over a 30-month period in the multicenter osteoarthritis studyFrank W Roemer
Department of Radiology, Boston University Medical Center, 820 Harrison Ave, FGH Building, Third Floor, Boston, MA 02118, USA
Radiology 252:772-80. 2009..To assess baseline factors that may predict fast tibiofemoral cartilage loss over a 30-month period...
Facet orientation and tropism: associations with spondylolysisLeonid Kalichman
Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, USA
J Spinal Disord Tech 23:101-5. 2010..Cross-sectional study...
Using magnetic resonance imaging to determine the compartmental prevalence of knee joint structural damageJ J Stefanik
Boston University School of Medicine, Boston, MA, USA Electronic address
Osteoarthritis Cartilage 21:695-9. 2013..A secondary aim was to evaluate the patterns of compartmental involvement in knees with pain, between men and women, and in different age and body mass index (BMI) categories...
Three-dimensional turbo spin-echo magnetic resonance imaging (MRI) and semiquantitative assessment of knee osteoarthritis: comparison with two-dimensional routine MRIM D Crema
Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine, Boston, MA, USA
Osteoarthritis Cartilage 21:428-33. 2013..The aim of this study was to evaluate three-dimensional (3D) turbo spin-echo (TSE) magnetic resonance imaging (MRI) for semiquantitative assessment of knee OA...
Urinary pentosidine does not predict cartilage loss among subjects with symptomatic knee OA: the BOKS StudyD J Hunter
Boston University Clinical Epidemiology Research and Training Unit, Boston, MA 02118, USA
Osteoarthritis Cartilage 15:93-7. 2007..We used data from a longitudinal observation study to determine if urinary pentosidine could serve as a marker to predict cartilage loss...
Osteoarthritis year 2011 in review: imaging in OA--a radiologists' perspectiveD Hayashi
Department of Radiology, Boston University School of Medicine, Boston, MA 02118, USA
Osteoarthritis Cartilage 20:207-14. 2012..This is not a systematic or comprehensive review and the selection of papers included is based on the expert opinions of the presenter, from a musculoskeletal radiologist's perspective...
High signal in knee osteophytes is not associated with knee painM Sengupta
Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, MA 02118, USA
Osteoarthritis Cartilage 14:413-7. 2006..CONCLUSION: High-signal osteophytes detected on MRI are not associated with the presence of pain, pain severity or the self-reported location of pain...
Lack of association between chondrocalcinosis and increased risk of cartilage loss in knees with osteoarthritis: results of two prospective longitudinal magnetic resonance imaging studiesT Neogi
Boston University, Boston, Massachusetts, USA
Arthritis Rheum 54:1822-8. 2006..To evaluate the relationship between chondrocalcinosis and the progression of knee osteoarthritis (OA) using longitudinal magnetic resonance imaging (MRI) assessments...
Relevant traumatic injury of the knee joint-MRI follow-up after 7-10 yearsMichel D Crema
Department of Radiology, Boston Medical Center, Boston University Medical School, Boston, MA 02118, USA
Eur J Radiol 72:473-9. 2009..To evaluate prospectively the history of relevant traumatic knee injuries at least 7 years after trauma by MRI focusing on the development of degenerative changes...
Volumetric and semiquantitative assessment of MRI-detected subchondral bone marrow lesions in knee osteoarthritis: a comparison of contrast-enhanced and non-enhanced imagingF W Roemer
Department of Radiology, Boston University Medical Center, Boston, MA 02118, USA
Osteoarthritis Cartilage 18:1062-6. 2010....
Osteoarthritis year 2010 in review: imagingD Hayashi
Department of Radiology, Boston University School of Medicine, Boston, MA 02118, USA
Osteoarthritis Cartilage 19:354-60. 2011..The peer-review process of OA imaging in any journal, therefore, should involve musculoskeletal radiologists experienced in OA research to ensure the publication of papers with scientifically sound contents...
MR findings in knee osteoarthritisAli Guermazi
Osteoporosis and Arthritis Research Group, Department of Radiology, University of California, 350 Parnassus Avenue, Suite 150, San Francisco, CA 94117, USA
Eur Radiol 13:1370-86. 2003....
Responsiveness, effect size, and smallest detectable difference of Magnetic Resonance Imaging in knee osteoarthritisD J Hunter
Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA 02118 2526, USA
Osteoarthritis Cartilage 14:A112-5. 2006....
Anatomical distribution of synovitis in knee osteoarthritis and its association with joint effusion assessed on non-enhanced and contrast-enhanced MRIF W Roemer
Quantitative Imaging Center QIC, Department of Radiology, Boston University Medical Center, Boston, MA 02118, USA
Osteoarthritis Cartilage 18:1269-74. 2010..To describe the anatomical distribution of synovitis and its association with joint effusion on non-enhanced and contrast-enhanced (CE) MRI in patients with knee osteoarthritis (OA)...
Vascular disease is associated with facet joint osteoarthritisP Suri
Department of Physical Medicine and Rehabilitation, Harvard Medical School, Boston, MA, USA
Osteoarthritis Cartilage 18:1127-32. 2010..We sought to examine whether vascular disease was associated with lumbar spine facet joint osteoarthritis (FJ OA) in a community-based population...
Increase in bone marrow lesions associated with cartilage loss: a longitudinal magnetic resonance imaging study of knee osteoarthritisDavid J Hunter
Boston University Clinical Epidemiology Research and Training Unit, Boston, Massachusetts, USA
Arthritis Rheum 54:1529-35. 2006..These questions were tested using longitudinal magnetic resonance imaging (MRI) data in a natural history study of symptomatic knee osteoarthritis (OA)...
Low levels of vitamin D and worsening of knee osteoarthritis: results of two longitudinal studiesDavid T Felson
Boston University School of Medicine, Boston, Massachusetts 02118, USA
Arthritis Rheum 56:129-36. 2007..To confirm reports that 25-hydroxyvitamin D (25[OH]D) deficiency is associated with an increased risk of joint space narrowing or cartilage loss in osteoarthritis (OA)...
MR imaging of intra- and periarticular soft tissues and subchondral bone in knee osteoarthritisMichel D Crema
Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine, 820 Harrison Avenue, FGH Building, 3 rd Floor, Boston, MA 02118, USA
Radiol Clin North Am 47:687-701. 2009..Cross-sectional and longitudinal evaluation has enabled us to understand their relevance in explaining pain and structural progression...
Magnetic resonance imaging-based semiquantitative and quantitative assessment in osteoarthritisFrank W Roemer
Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine, FGH Building, 3rd Floor, 820 Harrison Avenue, Boston, MA 02118, USA
Rheum Dis Clin North Am 35:521-55. 2009....
Association between age, sex, BMI and CT-evaluated spinal degeneration featuresLeonid Kalichman
Division of Research, New England Baptist Hospital, Boston, MA 02120, USA
J Back Musculoskelet Rehabil 22:189-95. 2009..The aim of our study was to evaluate the association between age, sex and body mass index (BMI) and lumbar spine degeneration features evaluated on computed tomography (CT) in a community-based sample...
Knee buckling: prevalence, risk factors, and associated limitations in functionDavid T Felson
Boston University School of Medicine, Hebrew SeniorLife, Brigham and Women s Hospital, and Boston Medical Center, Boston, Massachusetts 02118, USA
Ann Intern Med 147:534-40. 2007..Knee buckling is common in persons with advanced knee osteoarthritis and after orthopedic procedures. Its prevalence in the community is unknown...
Cartilage markers and their association with cartilage loss on magnetic resonance imaging in knee osteoarthritis: the Boston Osteoarthritis Knee StudyDavid J Hunter
Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, USA
Arthritis Res Ther 9:R108. 2007..With the exception of COMP, if changes in cartilage turnover in patients with symptomatic knee OA are associated with cartilage loss, they do not appear to affect systemic biomarker levels...
Biochemical markers of bone turnover and their association with bone marrow lesionsDavid J Hunter
Department of Epidemiology and Biostatistics, Boston University School of Medicine, Albany Street, Boston, Massachusetts 02118, USA
Arthritis Res Ther 10:R102. 2008..Our objective was to determine whether markers of bone resorption and formation could serve as markers for the presence of bone marrow lesions (BMLs)...
Subchondral cystlike lesions develop longitudinally in areas of bone marrow edema-like lesions in patients with or at risk for knee osteoarthritis: detection with MR imaging--the MOST studyMichel D Crema
Quantitative Imaging Center, Department of Radiology, and Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA 02118, USA
Radiology 256:855-62. 2010....
Fluctuation of knee pain and changes in bone marrow lesions, effusions, and synovitis on magnetic resonance imagingYuqing Zhang
Boston University School of Medicine, Boston, Massachusetts 02118, USA
Arthritis Rheum 63:691-9. 2011..This study was undertaken to determine whether pain resolution is accompanied by diminution of lesions in patients with knee OA...
Gastroenteropancreatic neuroendocrine tumors: multimodality imaging features with pathological correlationDaichi Hayashi
Department of Radiology, Boston University School of Medicine, Boston, MA 02118, USA
Jpn J Radiol 29:85-91. 2011..Modalities included are CT, MRI, ultrasonography, and nuclear medicine. Characteristic histological specimens of these lesions are presented...
Facet orientation and tropism: associations with facet joint osteoarthritis and degenerativesLeonid Kalichman
Boston University School of Medicine, Boston, MA, USA
Spine (Phila Pa 1976) 34:E579-85. 2009..Cross-sectional study...
Structural factors associated with malalignment in knee osteoarthritis: the Boston osteoarthritis knee studyDavid J Hunter
Clinical Epidemiology Research and Training Unit, Arthritis Center, Boston University, MA 02118, USA
J Rheumatol 32:2192-9. 2005..One of the mechanical influences on cartilage loss is limb alignment. We explored the structural factors associated with malalignment in subjects with symptomatic OA...
Hoffa's Fat Pad: Evaluation on Unenhanced MR Images as a Measure of Patellofemoral Synovitis in OsteoarthritisFrank W Roemer
Department of Radiology, Boston University Medical Center, MA, USA
AJR Am J Roentgenol 192:1696-700. 2009....
Synovitis detected on magnetic resonance imaging and its relation to pain and cartilage loss in knee osteoarthritisCatherine L Hill
Boston University School of Medicine, A203, 80 E Concord Street, Boston, MA 02118, USA
Ann Rheum Dis 66:1599-603. 2007..To examine the relationship between longitudinal fluctuations in synovitis with change in pain and cartilage in knee osteoarthritis...
Correlation of the development of knee pain with enlarging bone marrow lesions on magnetic resonance imagingDavid T Felson
Boston University School of Medicine, Boston, Massachusetts 02118, USA
Arthritis Rheum 56:2986-92. 2007..This study was undertaken to determine whether enlarging BMLs are associated with new knee pain...
MR imaging-based semiquantitative assessment in osteoarthritisFrank W Roemer
Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine, 820 Harrison Avenue, FGH Building, 3rd Floor, Boston, MA 02118, USA
Radiol Clin North Am 47:633-54. 2009..This article discusses the different available OA whole-organ scoring systems, focusing on MR imaging of the knee, and also reviews alternative approaches...
Subchondral bone attrition may be a reflection of compartment-specific mechanical load: the MOST StudyTuhina Neogi
Boston University School of Medicine, 650 Albany Street, Clinical Epidemiology Unit, Suite X 200, Boston, MA 02118, USA
Ann Rheum Dis 69:841-4. 2010..This study evaluated the effects of malalignment, which can cause focal excessive load, and systemic bone density on the presence and incidence of SBA...
Incidental meniscal findings on knee MRI in middle-aged and elderly personsMartin Englund
Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA 02118, USA
N Engl J Med 359:1108-15. 2008..However, there is a paucity of data regarding the prevalence of meniscal damage in the general population and the association of meniscal tears with knee symptoms and with radiographic evidence of osteoarthritis...
Meniscal tear in knees without surgery and the development of radiographic osteoarthritis among middle-aged and elderly persons: The Multicenter Osteoarthritis StudyMartin Englund
Boston University School of Medicine, Boston, Massachusetts, and Lund University Hospital, Lund, Sweden
Arthritis Rheum 60:831-9. 2009..Furthermore, meniscal damage is common. The aim of this study was to evaluate the association between meniscal damage in knees without surgery and the development of radiographic tibiofemoral OA...
Facet joint osteoarthritis and low back pain in the community-based populationLeonid Kalichman
Boston University School of Medicine, Boston, MA, USA
Spine (Phila Pa 1976) 33:2560-5. 2008..Cross-sectional study...
Spondylolysis and spondylolisthesis: prevalence and association with low back pain in the adult community-based populationLeonid Kalichman
Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, Massachusetts, USA
Spine (Phila Pa 1976) 34:199-205. 2009..Cross-sectional study...
Magnetic resonance imaging assessment of subchondral bone and soft tissues in knee osteoarthritisMichel D Crema
Department of Radiology, Quantitative Imaging Center, Boston University School of Medicine, 820 Harrison Avenue, FGH Building, 3rd Floor, Boston, MA 02118, USA
Rheum Dis Clin North Am 35:557-77. 2009..Cross-sectional and longitudinal evaluation has enabled practitioners to understand their relevance in explaining pain and structural progression...
Follicular non-Hodgkin's lymphomaD Hayashi
Department of Radiology, Boston University School of Medicine, FGH Building, 3rd Floor, Boston, MA 02118, USA
Clin Radiol 65:408-20. 2010..Radiologists should be aware of possible active residual mass, indolent recurrence, transformation, and association with other primary cancers in patients treated for follicular lymphoma...
Computed tomography-evaluated features of spinal degeneration: prevalence, intercorrelation, and association with self-reported low back painLeonid Kalichman
Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA 02118, USA
Spine J 10:200-8. 2010..Although the role of radiographic abnormalities in the etiology of nonspecific low back pain (LBP) is unclear, the frequent identification of these features on radiologic studies continues to influence medical decision making...
Micro-CT arthrography: a pilot study for the ex vivo visualization of the rat knee jointFrank W Roemer
Osteoporosis and Arthritis Research Group, Department of Radiology, University of California at San Francisco, San Francisco, CA 94117, USA
AJR Am J Roentgenol 184:1215-9. 2005..This technique represents an additional imaging and analysis tool in small-animal research...
Rheumatoid arthritis of the hand and wrist: comparison of three imaging techniquesBachir Taouli
Department of Radiology, University of California, San Francisco, 505 Parnassus Ave, Box 0628, San Francisco, CA 94143-0628, USA
AJR Am J Roentgenol 182:937-43. 2004....
Spinal stenosis prevalence and association with symptoms: the Framingham StudyLeonid Kalichman
Boston University, MA 02118, USA
Spine J 9:545-50. 2009..The prevalence of lumbar spinal stenosis (LSS) in the general population and association with low back pain (LBP) remain unclear...
A rapid, novel method of volumetric assessment of MRI-detected subchondral bone marrow lesions in knee osteoarthritisC Ratzlaff
Brigham and Women s Hosp, Boston, MA, USA Electronic address
Osteoarthritis Cartilage 21:806-14. 2013..To assess reliability and validity of a semi-automated quantitative method for osteoarthritis (OA)-related bone marrow lesion (BML) assessment in the femur and tibia...
Measurement of changes in trabecular bone at fracture sites using X-ray CT and automated image registration and processingJohn A Lynch
Osteoporosis and Arthritis Research Group, Department of Radiology, UCSF, 350 Parnassus Avenue, Suite 150, San Francisco, CA 94117, USA
J Orthop Res 22:362-7. 2004..The technique appears sensitive for measuring changes immediately post-fracture, and could have a role in examining potential effects of new therapies in patient cohorts...
Changes in paraspinal muscles and their association with low back pain and spinal degeneration: CT studyLeonid Kalichman
Boston University School of Medicine, Boston, MA, USA
Eur Spine J 19:1136-44. 2010..We conclude that the paraspinal muscle density decreases with age, and increases BMI. It is associated with at some levels FJOA, spondylolisthesis and disc narrowing at the same level, but not associated with occurrence of LBP...
Association between disc degeneration and degenerative spondylolisthesis? Pilot studyLeonid Kalichman
Boston University School of Medicine, Boston, MA 02118, USA
J Back Musculoskelet Rehabil 22:21-5. 2009..The aim of this pilot study was to test the generally believed hypothesis that intervertebral disc degeneration is a prerequisite for degenerative spondylolisthesis (DS)...
MDCT arthrography features of ulnocarpal impaction syndromeMichel D Crema
Department of Radiology, Quantitative Imaging Center, Boston University School of Medicine, Boston, MA, USA
AJR Am J Roentgenol 193:1376-81. 2009....
Use of positron emission tomography for response assessment of lymphoma: consensus of the Imaging Subcommittee of International Harmonization Project in LymphomaMalik E Juweid
Department of Radiology, University of Iowa, Iowa City, IA 52242, USA
J Clin Oncol 25:571-8. 2007..To develop guidelines for performing and interpreting positron emission tomography (PET) imaging for treatment assessment in patients with lymphoma both in clinical practice and in clinical trials...
Quantitative and qualitative assessment of closed fracture healing using computed tomography and conventional radiographyMikayel Grigoryan
Osteoporosis and Arthritis Research Group, Department of Radiology, 350 Parnassus Avenue, Suite 150, San Francisco, CA 94117, USA
Acad Radiol 10:1267-73. 2003..CT shows some advantages over conventional X-rays in evaluation of early fracture healing...
Recognizing and reporting osteoporotic vertebral fracturesMikayel Grigoryan
Osteoporosis and Arthritis Research Group, Department of Radiology, University of California San Francisco, 350 Parnassus Avenue, 94117, San Francisco, CA, USA
Eur Spine J 12:S104-12. 2003....
Short tau inversion recovery and proton density-weighted fat suppressed sequences for the evaluation of osteoarthritis of the knee with a 1.0 T dedicated extremity MRI: development of a time-efficient sequence protocolFrank W Roemer
Osteoporosis and Arthritis Research Group, Department of Radiology, University of California, San Francisco, USA
Eur Radiol 15:978-87. 2005..75/0.79), tibial cartilage (0.71/0.78). Optimization of sequence protocols consisting of three sequences results in time savings and cost efficiency in imaging of knee OA without loss of information over a more time consuming protocol...
Extranodal lymphoplasmacytoid lymphoma: spectrum of diseaseAli Guermazi
Department of Radiology, University of California at San Francisco, 350 Parnassus Avenue, Suite 150, San Francisco, CA 94117, USA
Eur Radiol 13:771-9. 2003..Nevertheless, localized forms, some of them extranodal, have been described. The cases that best represent the range of radiographic findings on X-ray, CT, and MR imaging are presented...
Invasive central nervous system aspergillosis in bone marrow transplantation recipients: an overviewAli Guermazi
Department of Radiology, University of California, San Francisco, 350 Parnassus Avenue, Suite 150, San Francisco, CA 94117, USA
Eur Radiol 13:377-88. 2003....
Mucosa-associated lymphoid tissue lymphoma: multimodality imaging and histopathologic correlationDaichi Hayashi
Department of Radiology, Boston University School of Medicine, MA 02118, USA
AJR Am J Roentgenol 195:W105-17. 2010..Radiologic and histopathologic findings need to be taken into account before making a diagnosis and treatment plan...
Full-limb and knee radiography assessments of varus-valgus alignment and their relationship to osteoarthritis disease features by magnetic resonance imagingSakeba N Issa
Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
Arthritis Rheum 57:398-406. 2007....
The relationship between cartilage loss on magnetic resonance imaging and radiographic progression in men and women with knee osteoarthritisShreyasee Amin
Division of Rheumatology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Arthritis Rheum 52:3152-9. 2005....
Longitudinal performance evaluation and validation of fixed-flexion radiography of the knee for detection of joint space lossMichael C Nevitt
University of California, San Francisco, CA 94107, USA
Arthritis Rheum 56:1512-20. 2007..We evaluated the ability of the nonfluoroscopically guided fixed-flexion radiography protocol to detect knee joint space loss over 3 years...
Relationship of meniscal damage, meniscal extrusion, malalignment, and joint laxity to subsequent cartilage loss in osteoarthritic kneesLeena Sharma
Division of Rheumatology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
Arthritis Rheum 58:1716-26. 2008..The aim of this study was to test whether meniscal damage, meniscal extrusion, malalignment, and laxity each predicted tibiofemoral cartilage loss after controlling for the other factors...
Fixed-flexion radiography of the knee provides reproducible joint space width measurements in osteoarthritisManish Kothari
Department of Scientific Client Services, Synarc, Inc, 575 Market Street, 17th Floor, San Francisco, CA 94105, USA
Eur Radiol 14:1568-73. 2004..0%). Fixed-flexion radiography of the knee using a positioning device provides consistent, reliable and reproducible measurement of minimum JSW in knee osteoarthritis without the need for concurrent fluoroscopic guidance...
