Research Topics
Species | Nathaniel M GreenSummaryAffiliation: Boston University Country: USA Publications
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Detail Information
Publications
Toll-like receptor driven B cell activation in the induction of systemic autoimmunityNathaniel M Green
Department of Microbiology, Boston University School of Medicine, Boston, MA 02118, USA
Semin Immunol 23:106-12. 2011..Further understanding of the role of specific receptors, cell subsets, and inhibitory signals that govern these TLR-associated pathways will enable future therapeutics to be tailored to specific categories of autoimmune disease...
Autoreactive B cells discriminate CpG-rich and CpG-poor DNA and this response is modulated by IFN-alphaMelissa B Uccellini
Department of Microbiology and Immunology Training Program, Boston University School of Medicine, Boston, MA 02118, USA
J Immunol 181:5875-84. 2008....
Activation of autoreactive B cells by endogenous TLR7 and TLR3 RNA ligandsNathaniel M Green
Department of Microbiology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
J Biol Chem 287:39789-99. 2012..These results identify parameters that define specific mammalian RNAs as ligands for TLRs...
Murine B cell response to TLR7 ligands depends on an IFN-beta feedback loopNathaniel M Green
Department of Microbiology, Boston University School of Medicine, Boston, MA 02118, USA
J Immunol 183:1569-76. 2009..These results highlight subtle differences in the IFN dependence of TLR7 responses compared with other TLR-mediated B cell responses...
