Matthew P Fox

Summary

Affiliation: Boston University
Country: USA

Publications

  1. pmc A novel approach to accounting for loss to follow-up when estimating the relationship between CD4 Count at ART initiation and mortality
    Matthew Fox
    Center for Global Health and Development, Boston University, Boston, Massachusetts, USA
    PLoS ONE 8:e69300. 2013
  2. pmc Low rates of treatment failure in children aged 2-59 months treated for severe pneumonia: a multisite pooled analysis
    Matthew P Fox
    Center for Global Health and Development, Boston University, Boston, MA, USA
    Clin Infect Dis 56:978-87. 2013
  3. pmc Treatment outcomes after 7 years of public-sector HIV treatment
    Matthew P Fox
    Center for Global Health and Development, School of Public Health, Boston University, Boston, Massachusetts, USA
    AIDS 26:1823-8. 2012
  4. pmc Rates and predictors of failure of first-line antiretroviral therapy and switch to second-line ART in South Africa
    Matthew P Fox
    Center for Global Health and Development, Boston University, 801 Massachusetts Ave, Boston, MA 02118, USA
    J Acquir Immune Defic Syndr 60:428-37. 2012
  5. pmc Effectiveness and safety of 30 mg versus 40 mg stavudine regimens: a cohort study among HIV-infected adults initiating HAART in South Africa
    Mhairi Maskew
    Clinical HIV Research Unit, Department of Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    J Int AIDS Soc 15:13. 2012
  6. pmc Prevalence and predictors of kaposi sarcoma herpes virus seropositivity: a cross-sectional analysis of HIV-infected adults initiating ART in Johannesburg, South Africa
    Mhairi Maskew
    Clinical HIV Research Unit, Department of Medicine, Faculty of Health Sciences, University of the Witwatersrand York Avenue, Johannesburg 2193, South Africa
    Infect Agent Cancer 6:22. 2011
  7. pmc Do the socioeconomic impacts of antiretroviral therapy vary by gender? A longitudinal study of Kenyan agricultural worker employment outcomes
    Bruce A Larson
    Department of International Health, Boston University School of Public Health, Boston, MA 02118, USA
    BMC Public Health 9:240. 2009
  8. ncbi request reprint The impact of HIV/AIDS on labour productivity in Kenya
    Matthew P Fox
    Center for International Health and Development, Boston University School of Public Health, Boston, MA 02118, USA
    Trop Med Int Health 9:318-24. 2004
  9. ncbi request reprint A sensitivity analysis of a randomized controlled trial of zinc in treatment of falciparum malaria in children
    Matthew P Fox
    Center for International Health and Development, Boston University School of Public Health, 85 East Concord St, 5th Floor, Boston, MA 02118, USA
    Contemp Clin Trials 26:281-9. 2005
  10. ncbi request reprint A method to automate probabilistic sensitivity analyses of misclassified binary variables
    Matthew P Fox
    Department of International Health, Boston University School of Public Health, Boston, MA, USA
    Int J Epidemiol 34:1370-6. 2005

Detail Information

Publications47

  1. pmc A novel approach to accounting for loss to follow-up when estimating the relationship between CD4 Count at ART initiation and mortality
    Matthew Fox
    Center for Global Health and Development, Boston University, Boston, Massachusetts, USA
    PLoS ONE 8:e69300. 2013
    ..While CD4 strongly predicts mortality on antiretroviral therapy (ART), estimates from programmatic data suffer from incomplete patient outcomes...
  2. pmc Low rates of treatment failure in children aged 2-59 months treated for severe pneumonia: a multisite pooled analysis
    Matthew P Fox
    Center for Global Health and Development, Boston University, Boston, MA, USA
    Clin Infect Dis 56:978-87. 2013
    ..Despite advances in childhood pneumonia management, it remains a major killer of children worldwide. We sought to estimate global treatment failure rates in children aged 2-59 months with World Health Organization-defined severe pneumonia...
  3. pmc Treatment outcomes after 7 years of public-sector HIV treatment
    Matthew P Fox
    Center for Global Health and Development, School of Public Health, Boston University, Boston, Massachusetts, USA
    AIDS 26:1823-8. 2012
    ..To assess outcomes over the first 7 years of antiretroviral therapy (ART) at Themba Lethu Clinic, Johannesburg, South Africa...
  4. pmc Rates and predictors of failure of first-line antiretroviral therapy and switch to second-line ART in South Africa
    Matthew P Fox
    Center for Global Health and Development, Boston University, 801 Massachusetts Ave, Boston, MA 02118, USA
    J Acquir Immune Defic Syndr 60:428-37. 2012
    ..To measure rates and predictors of virologic failure and switch to second-line antiretroviral therapy (ART) in South Africa...
  5. pmc Effectiveness and safety of 30 mg versus 40 mg stavudine regimens: a cohort study among HIV-infected adults initiating HAART in South Africa
    Mhairi Maskew
    Clinical HIV Research Unit, Department of Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    J Int AIDS Soc 15:13. 2012
    ....
  6. pmc Prevalence and predictors of kaposi sarcoma herpes virus seropositivity: a cross-sectional analysis of HIV-infected adults initiating ART in Johannesburg, South Africa
    Mhairi Maskew
    Clinical HIV Research Unit, Department of Medicine, Faculty of Health Sciences, University of the Witwatersrand York Avenue, Johannesburg 2193, South Africa
    Infect Agent Cancer 6:22. 2011
    ..abstract:..
  7. pmc Do the socioeconomic impacts of antiretroviral therapy vary by gender? A longitudinal study of Kenyan agricultural worker employment outcomes
    Bruce A Larson
    Department of International Health, Boston University School of Public Health, Boston, MA 02118, USA
    BMC Public Health 9:240. 2009
    ....
  8. ncbi request reprint The impact of HIV/AIDS on labour productivity in Kenya
    Matthew P Fox
    Center for International Health and Development, Boston University School of Public Health, Boston, MA 02118, USA
    Trop Med Int Health 9:318-24. 2004
    ..To estimate the impact of HIV/AIDS on individual labour productivity during disease progression...
  9. ncbi request reprint A sensitivity analysis of a randomized controlled trial of zinc in treatment of falciparum malaria in children
    Matthew P Fox
    Center for International Health and Development, Boston University School of Public Health, 85 East Concord St, 5th Floor, Boston, MA 02118, USA
    Contemp Clin Trials 26:281-9. 2005
    ..We examined the impact of different sources of bias on a randomized controlled trial of the efficacy of zinc as an adjuvant to malaria therapy in reducing time to total parasite clearance...
  10. ncbi request reprint A method to automate probabilistic sensitivity analyses of misclassified binary variables
    Matthew P Fox
    Department of International Health, Boston University School of Public Health, Boston, MA, USA
    Int J Epidemiol 34:1370-6. 2005
    ..Misclassification bias is present in most studies, yet uncertainty about its magnitude or direction is rarely quantified...
  11. pmc Initiating patients on antiretroviral therapy at CD4 cell counts above 200 cells/microl is associated with improved treatment outcomes in South Africa
    Matthew P Fox
    Center for Global Health and Development, Boston University, Boston, Massachusetts 02118, USA
    AIDS 24:2041-50. 2010
    ..To compare treatment outcomes by starting CD4 cell counts using data from the Comprehensive International Program of Research on AIDS-South Africa trial...
  12. pmc Patient retention in antiretroviral therapy programs up to three years on treatment in sub-Saharan Africa, 2007-2009: systematic review
    Matthew P Fox
    Center for Global Health and Development, Boston University, Boston, MA 02118, USA
    Trop Med Int Health 15:1-15. 2010
    ..To estimate the proportion of all-cause adult patient attrition from antiretroviral therapy (ART) programs in service delivery settings in sub-Saharan Africa through 36 months on treatment...
  13. pmc Improvements in physical wellbeing over the first two years on antiretroviral therapy in western Kenya
    Matthew P Fox
    Department of International Health, Center for Global Health and Development, School of Public Health, Boston University, Boston, MA, USA
    AIDS Care 22:137-45. 2010
    ..These improvements in physical wellbeing will be important in sustaining the long-term success of HIV treatment programs...
  14. pmc Barriers to initiation of antiretroviral treatment in rural and urban areas of Zambia: a cross-sectional study of cost, stigma, and perceptions about ART
    Matthew P Fox
    Center for Global Health and Development, Boston University, MA, USA
    J Int AIDS Soc 13:8. 2010
    ..Understanding why patients opt out of care, or are unable to opt in, is important to achieving the goal of universal access...
  15. doi request reprint High rates of survival, immune reconstitution, and virologic suppression on second-line antiretroviral therapy in South Africa
    Matthew P Fox
    Center for Global Health and Development, Boston University, Boston, MA 02118, USA
    J Acquir Immune Defic Syndr 53:500-6. 2010
    ..As rates of treatment failure over the first year on second-line therapy were low, provision of second-line treatment to patients who fail their first-line ART should be considered a high priority in resource-poor settings...
  16. ncbi request reprint Resolving design problems in equivalency trials
    Matthew P Fox
    Center for International Health and Development, Boston University School of Public Health, Boston, Massachusetts, USA
    J Pediatr 149:12-6. 2006
  17. pmc Role of breastfeeding cessation in mediating the relationship between maternal HIV disease stage and increased child mortality among HIV-exposed uninfected children
    Matthew P Fox
    Center for International Health and Development, Boston University, Boston, MA 02118, USA
    Int J Epidemiol 38:569-76. 2009
    ..Maternal CD4 count predicts child mortality in HIV-uninfected children born to HIV-infected women...
  18. pmc Reduced mortality associated with breast-feeding-acquired HIV infection and breast-feeding among HIV-infected children in Zambia
    Matthew P Fox
    Center for International Health and Development, Boston University, Boston, MA 02118, USA
    J Acquir Immune Defic Syndr 48:90-6. 2008
    ..This study assessed whether children infected postpartum have longer survival from time of infection versus those infected during gestation or delivery...
  19. ncbi request reprint Mammography surveillance and mortality in older breast cancer survivors
    Timothy L Lash
    Department of Epidemiology, Boston University School of Public Health, Boston, MA 02118, USA
    J Clin Oncol 25:3001-6. 2007
    ..Our purpose is to estimate the effectiveness of surveillance mammography in a cohort of breast cancer survivors with complete ascertainment of surveillance mammograms and negligible losses to follow-up...
  20. doi request reprint Antiretroviral therapy, labor productivity, and sex: a longitudinal cohort study of tea pluckers in Kenya
    Bruce A Larson
    Center for Global Health and Development, Boston University, Boston, MA, USA
    AIDS 27:115-23. 2013
    ..To estimate the impact of antiretroviral therapy (ART) on labor productivity and income using detailed employment data from two large tea plantations in western Kenya for HIV-infected tea pluckers who initiated ART...
  21. doi request reprint Early effects of antiretroviral therapy on work performance: preliminary results from a cohort study of Kenyan agricultural workers
    Bruce A Larson
    Center for International Health and Development, Boston University, Boston, Massachusetts 02118, USA
    AIDS 22:421-5. 2008
    ..This paper estimates the impact of antiretroviral therapy (ART) on days harvesting tea per month for tea-estate workers in Kenya. Such information is needed to assess the potential economic benefits of providing treatment to working adults...
  22. pmc Cohort profile: the Themba Lethu Clinical Cohort, Johannesburg, South Africa
    Matthew P Fox
    Centre for Global Health and Development, Boston University, Boston, MA, USA
    Int J Epidemiol 42:430-9. 2013
    ..The data collected include demographics, clinical visit data, laboratory data, medication history and clinical diagnoses. Requests for collaborations on analyses can be submitted to our data centre...
  23. pmc Early loss to follow up after enrolment in pre-ART care at a large public clinic in Johannesburg, South Africa
    Bruce A Larson
    Center for Global Health and Development, Boston University School of Public Health, Boston, MA 02118, USA
    Trop Med Int Health 15:43-7. 2010
    ..To estimate loss to follow up (LTFU) between initial enrollment and the first scheduled return medical visit of a pre-antiretroviral therapy (ART) care program for patients not eligible for ART...
  24. pmc Using vital registration data to update mortality among patients lost to follow-up from ART programmes: evidence from the Themba Lethu Clinic, South Africa
    Matthew P Fox
    Center for Global Health and Development, Boston University, MA, USA
    Trop Med Int Health 15:405-13. 2010
    ..To estimate the rates of mortality in patients lost to follow-up (LTFU) from a large urban public sector HIV clinic in South Africa...
  25. pmc Rapid point-of-care CD4 testing at mobile HIV testing sites to increase linkage to care: an evaluation of a pilot program in South Africa
    Bruce A Larson
    Department of International Health, Center for Global Health and Development, Boston University School of Public Health, 801 Massachusetts Avenue, Crosstown 3rd Floor, Boston, MA 02118, USA
    J Acquir Immune Defic Syndr 61:e13-7. 2012
    ..We report results from this pilot program for patients testing positive (n = 508) from May to October 2010...
  26. pmc Lost opportunities to complete CD4+ lymphocyte testing among patients who tested positive for HIV in South Africa
    Bruce A Larson
    Center for Global Health and Development, Boston University School of Public Health, MA 02118, United States of America
    Bull World Health Organ 88:675-80. 2010
    ....
  27. pmc The interplay between CD4 cell count, viral load suppression and duration of antiretroviral therapy on mortality in a resource-limited setting
    Alana T Brennan
    Center for Global Health and Development, Boston University, Boston, MA, USA Health Economics and Epidemiology Research Office, University of the Witwatersrand, Johannesburg, South Africa
    Trop Med Int Health 18:619-31. 2013
    ..To examine the interaction between CD4 cell count, viral load suppression and duration of antiretroviral therapy (ART) on mortality...
  28. pmc The net cost of incorporating resistance testing into HIV/AIDS treatment in South Africa: a Markov model with primary data
    Sydney Rosen
    Center for Global Health and Development, Boston University, Boston, MA, USA
    J Int AIDS Soc 14:24. 2011
    ..We modelled the net cost of adding resistance testing for patients with virological failure and retaining patients without resistance on first-line therapy, rather than switching all failures to second-line therapy...
  29. pmc Patient retention in antiretroviral therapy programs in sub-Saharan Africa: a systematic review
    Sydney Rosen
    Center for International Health and Development, Boston University School of Public Health, Boston, Massachusetts, United States of America
    PLoS Med 4:e298. 2007
    ..In this paper we present a systematic review of patient retention in ART programs in sub-Saharan Africa...
  30. pmc Retention in HIV care between testing and treatment in sub-Saharan Africa: a systematic review
    Sydney Rosen
    Center for Global Health and Development, Boston University, Boston, Massachusetts, USA
    PLoS Med 8:e1001056. 2011
    ..We conducted a systematic review of pre-ART retention in care in Africa...
  31. pmc Increases in regimen durability associated with the introduction of tenofovir at a large public-sector clinic in Johannesburg, South Africa
    Alana T Brennan
    Center for Global Health and Development, Boston University, Boston, MA, USA Health Economics and Epidemiology Research Office, Faculty of Health Sciences, Department of Internal Medicine, School of Clinical Medicine, University of the Witwatersrand, Johannesburg, South Africa
    J Int AIDS Soc 16:18794. 2013
    ..Conclusions: The decline in single-drug substitutions is associated with the introduction of tenofovir. Tenofovir use could improve regimen durability and treatment outcomes in resource-limited settings. ..
  32. pmc Rates and cost of hospitalization before and after initiation of antiretroviral therapy in urban and rural settings in South Africa
    Gesine Meyer-Rath
    Center for Global Health and Development, Boston University, Boston, MA, USA
    J Acquir Immune Defic Syndr 62:322-328. 2013
    ..Raising ART eligibility thresholds could avoid the high cost of hospitalization before and immediately after ART initiation...
  33. pmc The importance of clinic attendance in the first six months on antiretroviral treatment: a retrospective analysis at a large public sector HIV clinic in South Africa
    Alana T Brennan
    Center for Global Health and Development, Boston University, Boston, MA, USA
    J Int AIDS Soc 13:49. 2010
    ..Adherence to care and treatment are essential for HIV-infected individuals to benefit from antiretroviral therapy (ART). We sought to quantify the effects on treatment outcomes of missing visits soon after initiating ART...
  34. pmc How to estimate the cost of point-of-care CD4 testing in program settings: an example using the Alere Pima Analyzer in South Africa
    Bruce Larson
    Center for Global Health and Development, Boston University, Boston, Massachusetts, United States of America
    PLoS ONE 7:e35444. 2012
    ..The details of the program setting matter significantly for the cost estimate, so that such details should be clearly documented to improve the consistency, transparency, and comparability of cost estimates...
  35. ncbi request reprint Using probabilistic corrections to account for abstractor agreement in medical record reviews
    Timothy L Lash
    Boston University School of Public Health, Boston, MA 02118, USA
    Am J Epidemiol 165:1454-61. 2007
    ..While many investigators use reliability data only as a metric for data quality, a more thorough approach can also quantitatively depict the uncertainty in the observed associations...
  36. pmc Frequency and trajectory of abnormalities in respiratory rate, temperature and oxygen saturation in severe pneumonia in children
    Rasa Izadnegahdar
    Center for Global Health and Development, Boston University, Boston, MA 02118, USA
    Pediatr Infect Dis J 31:863-5. 2012
    ....
  37. pmc Revisiting pneumonia and exposure status in infants born to HIV-infected mothers
    Rasa Izadnegahdar
    From the Center for Global Health and Development, Boston University Department of Epidemiology, Boston University School of Public Health, Boston, MA Pediatrics Department, N Mandela School of Medicine, University of KwaZulu Natal, Durban, South Africa Department of Maternal Newborn Child and Adolescent Health, World Health Organization, Geneva, Switzerland and Department of International Health, Boston University School of Public Health, Boston, MA
    Pediatr Infect Dis J 33:70-2. 2014
    ..Additional prospective studies aimed at better understanding this population are needed. ..
  38. ncbi request reprint Adherence to tamoxifen over the five-year course
    Timothy L Lash
    Department of Epidemiology, Boston University School of Public Health, Boston, MA 02118, USA
    Breast Cancer Res Treat 99:215-20. 2006
    ..To estimate the proportion of older women who fail to complete 5 years of tamoxifen therapy and to identify predictors of non-adherence...
  39. pmc High frequency of multidrug-resistant gram-negative rods in 2 neonatal intensive care units in the Philippines
    Jennifer M Litzow
    Department of Pediatrics, Boston Medical Center, Boston, Massachusetts, USA
    Infect Control Hosp Epidemiol 30:543-9. 2009
    ..Although hospital-acquired infections appear to be a growing threat to the survival of newborns in the developing world, the epidemiology of this problem remains poorly characterized...
  40. pmc Effect of training traditional birth attendants on neonatal mortality (Lufwanyama Neonatal Survival Project): randomised controlled study
    Christopher J Gill
    Center for Global Health and Development, Boston University, Boston, MA, USA
    BMJ 342:d346. 2011
    ..To determine whether training traditional birth attendants to manage several common perinatal conditions could reduce neonatal mortality in the setting of a resource poor country with limited access to healthcare...
  41. pmc Cough aerosols of Mycobacterium tuberculosis predict new infection: a household contact study
    Edward C Jones-Lopez
    Section of Infectious Diseases, Department of Medicine, Boston Medical Center and Boston University School of Medicine, Boston, MA 02118, USA
    Am J Respir Crit Care Med 187:1007-15. 2013
    ..Airborne transmission of Mycobacterium tuberculosis results from incompletely characterized host, bacterial, and environmental factors. Sputum smear microscopy is associated with considerable variability in transmission...
  42. ncbi request reprint Reduced mortality rate associated with annual mammograms after breast cancer therapy
    Timothy L Lash
    Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts 02118, USA
    Breast J 12:2-6. 2006
    ..77 (95% confidence interval [CI] 0.53-1.1). These results are consistent with a protective effect of regular surveillance mammography after completing therapy for early stage breast cancer...
  43. pmc Global strategies to reduce the price of antiretroviral medicines: evidence from transactional databases
    Brenda Waning
    Boston University School of Medicine, Boston, MA 02118, United States of America
    Bull World Health Organ 87:520-8. 2009
    ....
  44. pmc Prevalent tuberculosis and mortality among HAART initiators
    Daniel Westreich
    Department of Obstetrics and Gynecology, Duke Global Health Institute, Duke University, Durham, North Carolina, USA
    AIDS 26:770-3. 2012
    ..In reanalysis, treatment for tuberculosis at time of HAART initiation remained unassociated with increased risks of all-cause mortality, with adjusted hazard ratios ranging from 1.00 to 1.09...
  45. pmc Failure of standard antimicrobial therapy in children aged 3-59 months with mild or asymptomatic HIV infection and severe pneumonia
    Prakash Jeena
    Department of Paediatrics and Child Health, King Edward Hospital, University of KwaZulu Natal, Durban, South Africa
    Bull World Health Organ 84:269-75. 2006
    ....
  46. pmc Under utilization of surveillance mammography among older breast cancer survivors
    Terry S Field
    Meyers Primary Care Institute, Worcester, MA 01605, USA
    J Gen Intern Med 23:158-63. 2008
    ..Annual surveillance mammography is recommended for follow-up of women with a history of breast cancer. We examined surveillance mammography among breast cancer survivors who were enrolled in integrated healthcare systems...
  47. doi request reprint Ambulatory short-course high-dose oral amoxicillin for treatment of severe pneumonia in children: a randomised equivalency trial
    Tabish Hazir
    Children s Hospital, Pakistan Institute of Medical Sciences, Islamabad, Pakistan
    Lancet 371:49-56. 2008
    ..Our aim was to determine whether home treatment with high-dose oral amoxicillin and inpatient treatment with parenteral ampicillin were equivalent for the treatment of severe pneumonia in children...