Research Topics
| Matthew P FoxSummaryAffiliation: Boston University Country: USA Publications
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Publications
Low rates of treatment failure in children aged 2-59 months treated for severe pneumonia: a multisite pooled analysisMatthew P Fox
Center for Global Health and Development, Boston University, Boston, MA, USA
Clin Infect Dis 56:978-87. 2013..Despite advances in childhood pneumonia management, it remains a major killer of children worldwide. We sought to estimate global treatment failure rates in children aged 2-59 months with World Health Organization-defined severe pneumonia...
Treatment outcomes after 7 years of public-sector HIV treatmentMatthew P Fox
Center for Global Health and Development, School of Public Health, Boston University, Boston, Massachusetts, USA
AIDS 26:1823-8. 2012..To assess outcomes over the first 7 years of antiretroviral therapy (ART) at Themba Lethu Clinic, Johannesburg, South Africa...- Rates and predictors of failure of first-line antiretroviral therapy and switch to second-line ART in South AfricaMatthew P Fox
Center for Global Health and Development, Boston University, 801 Massachusetts Ave, Boston, MA 02118, USA
J Acquir Immune Defic Syndr 60:428-37. 2012..To measure rates and predictors of virologic failure and switch to second-line antiretroviral therapy (ART) in South Africa... - Effectiveness and safety of 30 mg versus 40 mg stavudine regimens: a cohort study among HIV-infected adults initiating HAART in South AfricaMhairi Maskew
Clinical HIV Research Unit, Department of Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
J Int AIDS Soc 15:13. 2012.... - Prevalence and predictors of kaposi sarcoma herpes virus seropositivity: a cross-sectional analysis of HIV-infected adults initiating ART in Johannesburg, South AfricaMhairi Maskew
Clinical HIV Research Unit, Department of Medicine, Faculty of Health Sciences, University of the Witwatersrand York Avenue, Johannesburg 2193, South Africa
Infect Agent Cancer 6:22. 2011..abstract:.. - Do the socioeconomic impacts of antiretroviral therapy vary by gender? A longitudinal study of Kenyan agricultural worker employment outcomesBruce A Larson
Department of International Health, Boston University School of Public Health, Boston, MA 02118, USA
BMC Public Health 9:240. 2009.... 
The impact of HIV/AIDS on labour productivity in KenyaMatthew P Fox
Center for International Health and Development, Boston University School of Public Health, Boston, MA 02118, USA
Trop Med Int Health 9:318-24. 2004..To estimate the impact of HIV/AIDS on individual labour productivity during disease progression...- Barriers to initiation of antiretroviral treatment in rural and urban areas of Zambia: a cross-sectional study of cost, stigma, and perceptions about ARTMatthew P Fox
Center for Global Health and Development, Boston University, MA, USA
J Int AIDS Soc 13:8. 2010..Understanding why patients opt out of care, or are unable to opt in, is important to achieving the goal of universal access... - High rates of survival, immune reconstitution, and virologic suppression on second-line antiretroviral therapy in South AfricaMatthew P Fox
Center for Global Health and Development, Boston University, Boston, MA 02118, USA
J Acquir Immune Defic Syndr 53:500-6. 2010..As rates of treatment failure over the first year on second-line therapy were low, provision of second-line treatment to patients who fail their first-line ART should be considered a high priority in resource-poor settings... - Improvements in physical wellbeing over the first two years on antiretroviral therapy in western KenyaMatthew P Fox
Department of International Health, Center for Global Health and Development, School of Public Health, Boston University, Boston, MA, USA
AIDS Care 22:137-45. 2010..These improvements in physical wellbeing will be important in sustaining the long-term success of HIV treatment programs... - Patient retention in antiretroviral therapy programs up to three years on treatment in sub-Saharan Africa, 2007-2009: systematic reviewMatthew P Fox
Center for Global Health and Development, Boston University, Boston, MA 02118, USA
Trop Med Int Health 15:1-15. 2010..To estimate the proportion of all-cause adult patient attrition from antiretroviral therapy (ART) programs in service delivery settings in sub-Saharan Africa through 36 months on treatment... - Initiating patients on antiretroviral therapy at CD4 cell counts above 200 cells/microl is associated with improved treatment outcomes in South AfricaMatthew P Fox
Center for Global Health and Development, Boston University, Boston, Massachusetts 02118, USA
AIDS 24:2041-50. 2010..To compare treatment outcomes by starting CD4 cell counts using data from the Comprehensive International Program of Research on AIDS-South Africa trial... - Role of breastfeeding cessation in mediating the relationship between maternal HIV disease stage and increased child mortality among HIV-exposed uninfected childrenMatthew P Fox
Center for International Health and Development, Boston University, Boston, MA 02118, USA
Int J Epidemiol 38:569-76. 2009..Maternal CD4 count predicts child mortality in HIV-uninfected children born to HIV-infected women... - Reduced mortality associated with breast-feeding-acquired HIV infection and breast-feeding among HIV-infected children in ZambiaMatthew P Fox
Center for International Health and Development, Boston University, Boston, MA 02118, USA
J Acquir Immune Defic Syndr 48:90-6. 2008..This study assessed whether children infected postpartum have longer survival from time of infection versus those infected during gestation or delivery... - A sensitivity analysis of a randomized controlled trial of zinc in treatment of falciparum malaria in childrenMatthew P Fox
Center for International Health and Development, Boston University School of Public Health, 85 East Concord St, 5th Floor, Boston, MA 02118, USA
Contemp Clin Trials 26:281-9. 2005..We examined the impact of different sources of bias on a randomized controlled trial of the efficacy of zinc as an adjuvant to malaria therapy in reducing time to total parasite clearance... - Resolving design problems in equivalency trialsMatthew P Fox
Center for International Health and Development, Boston University School of Public Health, Boston, Massachusetts, USA
J Pediatr 149:12-6. 2006 - A method to automate probabilistic sensitivity analyses of misclassified binary variablesMatthew P Fox
Department of International Health, Boston University School of Public Health, Boston, MA, USA
Int J Epidemiol 34:1370-6. 2005..Misclassification bias is present in most studies, yet uncertainty about its magnitude or direction is rarely quantified... - Mammography surveillance and mortality in older breast cancer survivorsTimothy L Lash
Department of Epidemiology, Boston University School of Public Health, Boston, MA 02118, USA
J Clin Oncol 25:3001-6. 2007..Our purpose is to estimate the effectiveness of surveillance mammography in a cohort of breast cancer survivors with complete ascertainment of surveillance mammograms and negligible losses to follow-up... - Early effects of antiretroviral therapy on work performance: preliminary results from a cohort study of Kenyan agricultural workersBruce A Larson
Center for International Health and Development, Boston University, Boston, Massachusetts 02118, USA
AIDS 22:421-5. 2008..This paper estimates the impact of antiretroviral therapy (ART) on days harvesting tea per month for tea-estate workers in Kenya. Such information is needed to assess the potential economic benefits of providing treatment to working adults... - Early loss to follow up after enrolment in pre-ART care at a large public clinic in Johannesburg, South AfricaBruce A Larson
Center for Global Health and Development, Boston University School of Public Health, Boston, MA 02118, USA
Trop Med Int Health 15:43-7. 2010..To estimate loss to follow up (LTFU) between initial enrollment and the first scheduled return medical visit of a pre-antiretroviral therapy (ART) care program for patients not eligible for ART... - Using vital registration data to update mortality among patients lost to follow-up from ART programmes: evidence from the Themba Lethu Clinic, South AfricaMatthew P Fox
Center for Global Health and Development, Boston University, MA, USA
Trop Med Int Health 15:405-13. 2010..To estimate the rates of mortality in patients lost to follow-up (LTFU) from a large urban public sector HIV clinic in South Africa... - Rapid point-of-care CD4 testing at mobile HIV testing sites to increase linkage to care: an evaluation of a pilot program in South AfricaBruce A Larson
Department of International Health, Center for Global Health and Development, Boston University School of Public Health, 801 Massachusetts Avenue, Crosstown 3rd Floor, Boston, MA 02118, USA
J Acquir Immune Defic Syndr 61:e13-7. 2012..We report results from this pilot program for patients testing positive (n = 508) from May to October 2010... - Lost opportunities to complete CD4+ lymphocyte testing among patients who tested positive for HIV in South AfricaBruce A Larson
Center for Global Health and Development, Boston University School of Public Health, MA 02118, United States of America
Bull World Health Organ 88:675-80. 2010.... - The net cost of incorporating resistance testing into HIV/AIDS treatment in South Africa: a Markov model with primary dataSydney Rosen
Center for Global Health and Development, Boston University, Boston, MA, USA
J Int AIDS Soc 14:24. 2011..We modelled the net cost of adding resistance testing for patients with virological failure and retaining patients without resistance on first-line therapy, rather than switching all failures to second-line therapy... - Patient retention in antiretroviral therapy programs in sub-Saharan Africa: a systematic reviewSydney Rosen
Center for International Health and Development, Boston University School of Public Health, Boston, Massachusetts, United States of America
PLoS Med 4:e298. 2007..In this paper we present a systematic review of patient retention in ART programs in sub-Saharan Africa... - Antiretroviral therapy, labor productivity, and sex: a longitudinal cohort study of tea pluckers in KenyaBruce A Larson
Center for Global Health and Development, Boston University, Boston, MA, USA
AIDS 27:115-23. 2013..To estimate the impact of antiretroviral therapy (ART) on labor productivity and income using detailed employment data from two large tea plantations in western Kenya for HIV-infected tea pluckers who initiated ART... - Retention in HIV care between testing and treatment in sub-Saharan Africa: a systematic reviewSydney Rosen
Center for Global Health and Development, Boston University, Boston, Massachusetts, USA
PLoS Med 8:e1001056. 2011..We conducted a systematic review of pre-ART retention in care in Africa... - The importance of clinic attendance in the first six months on antiretroviral treatment: a retrospective analysis at a large public sector HIV clinic in South AfricaAlana T Brennan
Center for Global Health and Development, Boston University, Boston, MA, USA
J Int AIDS Soc 13:49. 2010..Adherence to care and treatment are essential for HIV-infected individuals to benefit from antiretroviral therapy (ART). We sought to quantify the effects on treatment outcomes of missing visits soon after initiating ART... - How to estimate the cost of point-of-care CD4 testing in program settings: an example using the Alere Pima Analyzer in South AfricaBruce Larson
Center for Global Health and Development, Boston University, Boston, Massachusetts, United States of America
PLoS ONE 7:e35444. 2012..The details of the program setting matter significantly for the cost estimate, so that such details should be clearly documented to improve the consistency, transparency, and comparability of cost estimates... - Using probabilistic corrections to account for abstractor agreement in medical record reviewsTimothy L Lash
Boston University School of Public Health, Boston, MA 02118, USA
Am J Epidemiol 165:1454-61. 2007..While many investigators use reliability data only as a metric for data quality, a more thorough approach can also quantitatively depict the uncertainty in the observed associations... - The interplay between CD4 cell count, viral load suppression and duration of antiretroviral therapy on mortality in a resource-limited settingAlana T Brennan
Center for Global Health and Development, Boston University, Boston, MA, USA Health Economics and Epidemiology Research Office, University of the Witwatersrand, Johannesburg, South Africa
Trop Med Int Health 18:619-31. 2013..To examine the interaction between CD4 cell count, viral load suppression and duration of antiretroviral therapy (ART) on mortality... - Frequency and trajectory of abnormalities in respiratory rate, temperature and oxygen saturation in severe pneumonia in childrenRasa Izadnegahdar
Center for Global Health and Development, Boston University, Boston, MA 02118, USA
Pediatr Infect Dis J 31:863-5. 2012.... - High frequency of multidrug-resistant gram-negative rods in 2 neonatal intensive care units in the PhilippinesJennifer M Litzow
Department of Pediatrics, Boston Medical Center, Boston, Massachusetts, USA
Infect Control Hosp Epidemiol 30:543-9. 2009..Although hospital-acquired infections appear to be a growing threat to the survival of newborns in the developing world, the epidemiology of this problem remains poorly characterized... - Adherence to tamoxifen over the five-year courseTimothy L Lash
Department of Epidemiology, Boston University School of Public Health, Boston, MA 02118, USA
Breast Cancer Res Treat 99:215-20. 2006..To estimate the proportion of older women who fail to complete 5 years of tamoxifen therapy and to identify predictors of non-adherence... - Effect of training traditional birth attendants on neonatal mortality (Lufwanyama Neonatal Survival Project): randomised controlled studyChristopher J Gill
Center for Global Health and Development, Boston University, Boston, MA, USA
BMJ 342:d346. 2011..To determine whether training traditional birth attendants to manage several common perinatal conditions could reduce neonatal mortality in the setting of a resource poor country with limited access to healthcare... - Global strategies to reduce the price of antiretroviral medicines: evidence from transactional databasesBrenda Waning
Boston University School of Medicine, Boston, MA 02118, United States of America
Bull World Health Organ 87:520-8. 2009.... - Reduced mortality rate associated with annual mammograms after breast cancer therapyTimothy L Lash
Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts 02118, USA
Breast J 12:2-6. 2006..77 (95% confidence interval [CI] 0.53-1.1). These results are consistent with a protective effect of regular surveillance mammography after completing therapy for early stage breast cancer... - Prevalent tuberculosis and mortality among HAART initiatorsDaniel Westreich
Department of Obstetrics and Gynecology, Duke Global Health Institute, Duke University, Durham, North Carolina, USA
AIDS 26:770-3. 2012..In reanalysis, treatment for tuberculosis at time of HAART initiation remained unassociated with increased risks of all-cause mortality, with adjusted hazard ratios ranging from 1.00 to 1.09... - Failure of standard antimicrobial therapy in children aged 3-59 months with mild or asymptomatic HIV infection and severe pneumoniaPrakash Jeena
Department of Paediatrics and Child Health, King Edward Hospital, University of KwaZulu Natal, Durban, South Africa
Bull World Health Organ 84:269-75. 2006.... - Under utilization of surveillance mammography among older breast cancer survivorsTerry S Field
Meyers Primary Care Institute, Worcester, MA 01605, USA
J Gen Intern Med 23:158-63. 2008..Annual surveillance mammography is recommended for follow-up of women with a history of breast cancer. We examined surveillance mammography among breast cancer survivors who were enrolled in integrated healthcare systems... - Ambulatory short-course high-dose oral amoxicillin for treatment of severe pneumonia in children: a randomised equivalency trialTabish Hazir
Children s Hospital, Pakistan Institute of Medical Sciences, Islamabad, Pakistan
Lancet 371:49-56. 2008..Our aim was to determine whether home treatment with high-dose oral amoxicillin and inpatient treatment with parenteral ampicillin were equivalent for the treatment of severe pneumonia in children...