R A Fielding

Summary

Affiliation: Boston University
Country: USA

Publications

  1. ncbi request reprint Effects of prior exercise on eccentric exercise-induced neutrophilia and enzyme release
    R A Fielding
    Department of Health Sciences, Sargent College of Health and Rehabilitation Sciences, Boston University, MA 02215, USA
    Med Sci Sports Exerc 32:359-64. 2000
  2. ncbi request reprint What are the dietary protein requirements of physically active individuals? New evidence on the effects of exercise on protein utilization during post-exercise recovery
    Roger A Fielding
    Human Physiology Laboratory, Department of Health Sciences, Boston University, Sargent College of Health and Rehabilitation Sciences, 635 Commonwealth Avenue, Boston, MA 02215, USA
    Nutr Clin Care 5:191-6. 2002
  3. ncbi request reprint High-velocity resistance training increases skeletal muscle peak power in older women
    Roger A Fielding
    Human Physiology Laboratory, Department of Health Sciences, Boston University Sargent College of Health and Rehabilitation Sciences, Boston, Massachusetts 02215, USA
    J Am Geriatr Soc 50:655-62. 2002
  4. ncbi request reprint Association of muscle power with functional status in community-dwelling elderly women
    M Foldvari
    Nutrition, Exercise Physiology, and Sarcopenia Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts 02111, USA
    J Gerontol A Biol Sci Med Sci 55:M192-9. 2000
  5. ncbi request reprint The reproducibility of the Bruce protocol exercise test for the determination of aerobic capacity in older women
    R A Fielding
    Human Physiology Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Med Sci Sports Exerc 29:1109-13. 1997
  6. ncbi request reprint Resistance training to counteract the catabolism of a low-protein diet in patients with chronic renal insufficiency. A randomized, controlled trial
    C Castaneda
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Ann Intern Med 135:965-76. 2001
  7. ncbi request reprint Effects of creatine supplementation on the energy cost of muscle contraction: a 31P-MRS study
    S A Smith
    Department of Health Sciences, Sargent College of Health and Rehabilitation Sciences, Boston University, Boston, Massachusetts 02215, USA
    J Appl Physiol 87:116-23. 1999
  8. pmc Marathon running transiently increases c-Jun NH2-terminal kinase and p38 activities in human skeletal muscle
    M D Boppart
    Research Division, Joslin Diabetes Center, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
    J Physiol 526:663-9. 2000
  9. pmc Assessment of analytical methods used to measure changes in body composition in the elderly and recommendations for their use in phase II clinical trials
    M S Lustgarten
    Nutrition, Exercise Physiology and Sarcopenia Laboratory, Jean Mayer USDA Human Research Center on Aging, Tufts University, Boston, MA 02111 1524, USA
    J Nutr Health Aging 15:368-75. 2011
  10. ncbi request reprint Aging of skeletal muscle: a 12-yr longitudinal study
    W R Frontera
    Department of Physical Medicine and Rehabilitation, Harvard Medical School and Spaulding Rehabilitation Hospital, Boston, MA 02114, USA
    J Appl Physiol 88:1321-6. 2000

Detail Information

Publications42

  1. ncbi request reprint Effects of prior exercise on eccentric exercise-induced neutrophilia and enzyme release
    R A Fielding
    Department of Health Sciences, Sargent College of Health and Rehabilitation Sciences, Boston University, MA 02215, USA
    Med Sci Sports Exerc 32:359-64. 2000
    ..The purpose of this study was to determine the effects of prior exercise on changes in circulating neutrophils, neutrophil activation, and myocellular enzymes following a standardized bout of eccentric exercise...
  2. ncbi request reprint What are the dietary protein requirements of physically active individuals? New evidence on the effects of exercise on protein utilization during post-exercise recovery
    Roger A Fielding
    Human Physiology Laboratory, Department of Health Sciences, Boston University, Sargent College of Health and Rehabilitation Sciences, 635 Commonwealth Avenue, Boston, MA 02215, USA
    Nutr Clin Care 5:191-6. 2002
    ..New evidence suggests that individuals engaging in strenuous activity consume a meal rich in amino acids and carbohydrate soon after the exercise bout or training session...
  3. ncbi request reprint High-velocity resistance training increases skeletal muscle peak power in older women
    Roger A Fielding
    Human Physiology Laboratory, Department of Health Sciences, Boston University Sargent College of Health and Rehabilitation Sciences, Boston, Massachusetts 02215, USA
    J Am Geriatr Soc 50:655-62. 2002
    ..We tested the hypothesis that a high-velocity resistance-training program (HI) would increase muscle power more than a traditional low-velocity resistance-training program (LO)...
  4. ncbi request reprint Association of muscle power with functional status in community-dwelling elderly women
    M Foldvari
    Nutrition, Exercise Physiology, and Sarcopenia Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts 02111, USA
    J Gerontol A Biol Sci Med Sci 55:M192-9. 2000
    ..We tested the hypothesis that peak muscle power is closely associated with self-reported functional status in sedentary elderly community-dwelling women...
  5. ncbi request reprint The reproducibility of the Bruce protocol exercise test for the determination of aerobic capacity in older women
    R A Fielding
    Human Physiology Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Med Sci Sports Exerc 29:1109-13. 1997
    ..The mean differences between tests and the high level of agreement between repeated tests suggests that a single measurement of VO2max can be performed to assess functional aerobic capacity in this population...
  6. ncbi request reprint Resistance training to counteract the catabolism of a low-protein diet in patients with chronic renal insufficiency. A randomized, controlled trial
    C Castaneda
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Ann Intern Med 135:965-76. 2001
    ..Chronic renal insufficiency leads to muscle wasting, which may be exacerbated by low-protein diets prescribed to delay disease progression. Resistance training increases protein utilization and muscle mass...
  7. ncbi request reprint Effects of creatine supplementation on the energy cost of muscle contraction: a 31P-MRS study
    S A Smith
    Department of Health Sciences, Sargent College of Health and Rehabilitation Sciences, Boston University, Boston, Massachusetts 02215, USA
    J Appl Physiol 87:116-23. 1999
    ..DeltaATP/J and DeltaATP/N were greatest at the onset of the exercise protocol (P < 0.01). In summary, creatine supplementation increased muscle PCr concentration, which did not affect muscle ATP cost of contraction...
  8. pmc Marathon running transiently increases c-Jun NH2-terminal kinase and p38 activities in human skeletal muscle
    M D Boppart
    Research Division, Joslin Diabetes Center, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
    J Physiol 526:663-9. 2000
    ..The differential activation of the p38 isoforms with exercise in human skeletal muscle indicates that these proteins may have distinct functions in vivo...
  9. pmc Assessment of analytical methods used to measure changes in body composition in the elderly and recommendations for their use in phase II clinical trials
    M S Lustgarten
    Nutrition, Exercise Physiology and Sarcopenia Laboratory, Jean Mayer USDA Human Research Center on Aging, Tufts University, Boston, MA 02111 1524, USA
    J Nutr Health Aging 15:368-75. 2011
    ....
  10. ncbi request reprint Aging of skeletal muscle: a 12-yr longitudinal study
    W R Frontera
    Department of Physical Medicine and Rehabilitation, Harvard Medical School and Spaulding Rehabilitation Hospital, Boston, MA 02114, USA
    J Appl Physiol 88:1321-6. 2000
    ....
  11. ncbi request reprint Aerobic exercise capacity remains normal despite impaired endothelial function in the micro- and macrocirculation of physically active IDDM patients
    A Veves
    Department of Medicine, Deaconess Joslin Foot Center, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    Diabetes 46:1846-52. 1997
    ..In addition, regular exercise training involving the lower extremities does not improve the endothelial function in the micro- and macrocirculation of the nonexercised upper extremity in type 1 diabetic patients...
  12. doi request reprint Lipogenic regulators are elevated with age and chronic overload in rat skeletal muscle
    D A Rivas
    Nutrition, Exercise Physiology and Sarcopenia Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA
    Acta Physiol (Oxf) 202:691-701. 2011
    ..The purpose of this study was to determine the effect of 28 days of overload on the storage of intramuscular triglycerides (IMTG) and metabolic regulators of lipid synthesis in young and old skeletal muscle...
  13. ncbi request reprint Static stretch increases c-Jun NH2-terminal kinase activity and p38 phosphorylation in rat skeletal muscle
    M D Boppart
    Research Division, Joslin Diabetes Center, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02215, USA
    Am J Physiol Cell Physiol 280:C352-8. 2001
    ..These studies suggest that the stretch component of a muscle contraction may be a major contributor to the increases in JNK activity and p38 phosphorylation observed after exercise in vivo...
  14. ncbi request reprint Randomized trial of progressive resistance training to counteract the myopathy of chronic heart failure
    C T Pu
    Nutrition, Exercise Physiology, and Sarcopenia Laboratory, Jean Mayer United States Department of Agriculture, Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    J Appl Physiol 90:2341-50. 2001
    ..These gains are largely explained by skeletal muscle and not resting cardiac adaptations...
  15. pmc Lower extremity muscle mass predicts functional performance in mobility-limited elders
    K F Reid
    Nutrition, Exercise Physiology and Sarcopenia Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    J Nutr Health Aging 12:493-8. 2008
    ..This study examined the influence of lower extremity body composition and muscle strength on the severity of mobility-disability in community-dwelling older adults...
  16. ncbi request reprint Muscle power of the ankle flexors predicts functional performance in community-dwelling older women
    T Suzuki
    Human Physiology Laboratory, Department of Health Sciences, Sargent College of Health and Rehabilitation Sciences, Boston University, Boston, Massachusetts 02215, USA
    J Am Geriatr Soc 49:1161-7. 2001
    ..CONCLUSION: These data suggest that ankle muscle power together with self-reported measures of health and physical functioning are essential components of functional mobility in older women with functional limitations...
  17. ncbi request reprint Weighted stair climbing in mobility-limited older people: a pilot study
    Jonathan Bean
    Department of Physical Medicine and Rehabilitation, Harvard Medical School, Spaulding Rehabilitation Hospital, Boston, Massachusetts, USA
    J Am Geriatr Soc 50:663-70. 2002
    ..To evaluate weighted stair climbing exercise (SCE) as a means of increasing lower extremity muscle power in mobility-limited older people...
  18. ncbi request reprint The lifestyle interventions and independence for elders (LIFE) pilot study: design and methods
    W Jack Rejeski
    Department of HES, Box 7868, Wake Forest University, Winston Salem, NC 27109, USA
    Contemp Clin Trials 26:141-54. 2005
    ..Other goals of this pilot phase include assessments of health-related quality of life and cost-effectiveness...
  19. ncbi request reprint Muscle impairments and behavioral factors mediate functional limitations and disability following stroke
    Nathan K Lebrasseur
    Department of Health Sciences, Sargent College of Health and Rehabilitation Sciences, Boston University, Boston, MA 02118, USA
    Phys Ther 86:1342-50. 2006
    ....
  20. ncbi request reprint Impact of muscle power and force on gait speed in disabled older men and women
    Anthony Cuoco
    Human Physiology Laboratory, Department of Health Sciences, Sargent College of Health and Rehabilitation Science, Boston University, 635 Commonwealth Ave, Boston, MA 02215, USA
    J Gerontol A Biol Sci Med Sci 59:1200-6. 2004
    ....
  21. ncbi request reprint Use of self-report to predict ability to walk 400 meters in mobility-limited older adults
    Stephen P Sayers
    Human Physiology Laboratory, Department of Health Sciences, Sargent College of Rehabilitation Sciences, Boston, Massachusetts, USA
    J Am Geriatr Soc 52:2099-103. 2004
    ....
  22. ncbi request reprint Validation of the Late-Life Function and Disability Instrument
    Stephen P Sayers
    Human Physiology Laboratory, Department of Health Sciences, Boston University, Boston, Massachusetts, USA
    J Am Geriatr Soc 52:1554-9. 2004
    ..To assess the concurrent and predictive validity of the Late-Life Function and Disability Instrument (LLFDI)...
  23. ncbi request reprint Increased Velocity Exercise Specific to Task (InVEST) training: a pilot study exploring effects on leg power, balance, and mobility in community-dwelling older women
    Jonathan F Bean
    Department of Physical Medicine and Rehabilitation, Harvard Medical School, Spaulding Rehabilitation Hospital, Boston, Massachusetts, USA
    J Am Geriatr Soc 52:799-804. 2004
    ..To evaluate a dynamic form of weighted vest exercise suitable for home use and designed to enhance muscle power, balance, and mobility...
  24. pmc Predictors of adherence to physical activity in the Lifestyle Interventions and Independence for Elders pilot study (LIFE-P)
    W Jack Rejeski
    Department of Health and Exercise Science, Box 7868, Wake Forest University, Winston Salem, NC 27109, USA
    Clin Interv Aging 2:485-94. 2007
    ..A prospective design was used to examine predictors of adherence to a physical activity intervention in older adults with compromised function...
  25. ncbi request reprint Assessment of lower extremity muscle power in functionally-limited elders
    Damien Callahan
    Human Physiology Laboratory, Department of Health Sciences, Sargent College of Health and Rehabilitation Sciences, Boston Univerisity, Boston, MA, USA
    Aging Clin Exp Res 19:194-9. 2007
    ..The purpose of this study was to assess the reliability and concurrent validity of a new methodology to evaluate lower extremity muscle power in older, functionally limited men and women...
  26. ncbi request reprint Creatine monohydrate as a therapeutic aid in muscular dystrophy
    Jared P Pearlman
    Nutrition, Exercise Physiology, and Sarcopenia Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts, USA
    Nutr Rev 64:80-8. 2006
    ..Though the mechanisms are still unknown, creatine has been shown to decrease cytoplasmic Ca2+ levels and increase intramuscular and cerebral phosphocreatine stores, providing potential musculoskeletal and neuroprotective effects...
  27. ncbi request reprint Skeletal muscle lipid deposition and insulin resistance: effect of dietary fatty acids and exercise
    Michael P Corcoran
    Lipid Metabolism Laboratory and the Nutrition, Exercise Physiology, and Sarcopenia Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 85:662-77. 2007
    ..This review summarizes the current understanding of the effects of elevated intramyocellular lipids on insulin signaling and how these effects may be altered by varying dietary fat composition and exercise...
  28. pmc Muscle fiber size and function in elderly humans: a longitudinal study
    Walter R Frontera
    Nutrition, Exercise Physiology, and Sarcopenia Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington St, Boston, MA 02111, USA
    J Appl Physiol 105:637-42. 2008
    ..This suggests that surviving fibers compensate to partially correct muscle size deficits in an attempt to maintain optimal force-generating capacity...
  29. ncbi request reprint Concordance and discordance between two measures of lower extremity function: 400 meter self-paced walk and SPPB
    Stephen P Sayers
    Human Physiology Laboratory, Department of Health Sciences, Sargent College of Rehabilitation Sciences, Boston University, USA
    Aging Clin Exp Res 18:100-6. 2006
    ..A secondary purpose was to determine whether the 400-m W could better discriminate physical performance among high functioning older adults by examining the distribution of 400-m W scores...
  30. ncbi request reprint Activity adherence and physical function in older adults with functional limitations
    Roger A Fielding
    Nutrition, Exercise Physiology, and Sarcopenia Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Med Sci Sports Exerc 39:1997-2004. 2007
    ..We examined adherence to the LIFE-P PA intervention for the first 12 months of the trial...
  31. ncbi request reprint Sex differences in single muscle fiber power in older adults
    Lisa S Krivickas
    Department of Physical Medicine and Rehabilitation, Spaulding Rehabilitation Hospital and Harvard Medical School, Boston, MA 02114, USA
    Med Sci Sports Exerc 38:57-63. 2006
    ..This study was conducted to determine whether differences in power at the single muscle fiber level contribute to sex differences in whole muscle power production in the elderly...
  32. ncbi request reprint Age-associated decrease in contraction-induced activation of downstream targets of Akt/mTor signaling in skeletal muscle
    Katsuhiko Funai
    Nutrition, Exercise Physiology, and Sarcopenia Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, 711 Washington St, Boston, MA 02111, USA
    Am J Physiol Regul Integr Comp Physiol 290:R1080-6. 2006
    ..These observations suggest that the anabolic response to muscle stimulation is attenuated with aging and may contribute to the limited capacity of hypertrophy in aged animals...
  33. ncbi request reprint Regulation of neuregulin/ErbB signaling by contractile activity in skeletal muscle
    Nathan K Lebrasseur
    Myocardial Biology Unit, Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston 02218, USA
    Am J Physiol Cell Physiol 284:C1149-55. 2003
    ..To our knowledge, this is the first demonstration of physiological regulation of NRG/ErbB signaling in any organ and implicates this pathway in the metabolic and proliferative responses of skeletal muscle to exercise...
  34. ncbi request reprint Changes in function and disability after resistance training: does velocity matter?: a pilot study
    Stephen P Sayers
    Human Physilogy Laboratory, Department of Health Science, Boston University, Boston, MA 02215, USA
    Am J Phys Med Rehabil 82:605-13. 2003
    ..To compare the effects of high- and low-velocity resistance training on functional performance and disability outcomes in physically limited older women...
  35. ncbi request reprint Differential activation of mTOR signaling by contractile activity in skeletal muscle
    Jascha D Parkington
    Dept of Health Sciences, Boston Univ, 635 Commonwealth Ave, Boston, MA 02215, USA
    Am J Physiol Regul Integr Comp Physiol 285:R1086-90. 2003
    ..Fiber type-dependent mTOR phosphorylation may be a molecular basis by which some fiber types are more susceptible to contraction-induced hypertrophy...
  36. ncbi request reprint Use of phosphocreatine kinetics to determine the influence of creatine on muscle mitochondrial respiration: an in vivo 31P-MRS study of oral creatine ingestion
    Sinclair A Smith
    Temple University, Neuromuscular Function Laboratory, Department of Occupational Therapy, 3307 North Broad St, Philadelphia, PA 19140, USA
    J Appl Physiol 96:2288-92. 2004
    ....
  37. ncbi request reprint Contraction-mediated mTOR, p70S6k, and ERK1/2 phosphorylation in aged skeletal muscle
    Jascha D Parkington
    Department of Health Sciences, Boston University, Boston, MA 02215, USA
    J Appl Physiol 97:243-8. 2004
    ..These observations suggest that the anabolic response to a single bout of contraction is attenuated with aging and may help explain the reduced capacity for hypertrophy in aged animals...
  38. ncbi request reprint High-intensity resistance training improves muscle strength, self-reported function, and disability in long-term stroke survivors
    Michelle M Ouellette
    Human Physiology Laboratory, Department of Health Sciences, Sargent College of Health and Rehabilitation Sciences, Boston University, Boston, Mass 02215, USA
    Stroke 35:1404-9. 2004
    ..To evaluate the efficacy of supervised high-intensity progressive resistance training (PRT) on lower extremity strength, function, and disability in older, long-term stroke survivors...
  39. ncbi request reprint Identification of a molecular signature of sarcopenia
    Paul G Giresi
    Department of Health Sciences, Boston University, Boston, Massachusetts, USA
    Physiol Genomics 21:253-63. 2005
    ..The sarcopenia signature developed here will be useful as a molecular model to judge the effectiveness of exercise and other therapeutic treatments aimed at ameliorating the effects of muscle loss associated with aging...
  40. ncbi request reprint Effect of leg muscle contraction velocity on functional performance in older men and women
    Stephen P Sayers
    Human Physiology Laboratory, Department of Health Sciences, Sargent College of Health and Rehabilitation Sciences, Boston University, Boston, Massachusetts, USA
    J Am Geriatr Soc 53:467-71. 2005
    ..To explore the relationship between impairment (skeletal muscle strength and contraction velocity) and function in community-dwelling older adults...
  41. ncbi request reprint The expression of neuregulin and erbB receptors in human skeletal muscle: effects of progressive resistance training
    Nathan K Lebrasseur
    Human Physiology Laboratory, Department of Health Sciences, Sargent College of Health and Rehabilitation Sciences, Boston University, Massachusetts, 02215, USA
    Eur J Appl Physiol 94:371-5. 2005
    ..Following PRT, a significant increase in erbB3 was observed. The ability to detect basal expression and alterations in response to physiologic stimuli merit further studies examining the role of this system in skeletal muscle...
  42. ncbi request reprint The relationship between leg power and physical performance in mobility-limited older people
    Jonathan F Bean
    Department of Physical Medicine and Rehabilitation, Harvard Medical School, Spaulding Rehabilitation Hospital, Boston, Massachusetts, USA
    J Am Geriatr Soc 50:461-7. 2002
    ..The purpose of this study was to assess the influence of leg power and leg strength on the physical performance of community-dwelling mobility-limited older people...