R C Ellison

Summary

Affiliation: Boston University
Country: USA

Publications

  1. pmc Apolipoprotein ε4 polymorphism does not modify the association between body mass index and high-density lipoprotein cholesterol: a cross-sectional cohort study
    Catherine R Rahilly-Tierney
    Massachusetts Veterans Epidemiology and Information Research Center MAVERIC, Boston VA Healthcare, Boston, Massachusetts, USA
    Lipids Health Dis 10:167. 2011
  2. pmc Evidence for a gene influencing heart rate on chromosome 5p13-14 in a meta-analysis of genome-wide scans from the NHLBI Family Blood Pressure Program
    Jason M Laramie
    Department of Neurology, Boston University School of Medicine, Boston, MA, USA
    BMC Med Genet 7:17. 2006
  3. pmc An investigation of the effects of lipid-lowering medications: genome-wide linkage analysis of lipids in the HyperGEN study
    Jun Wu
    Division of Statistical Genomics, Washington University School of Medicine, Campus Box 8506, 4444 Forest Park Boulevard, Saint Louis, MO 63108, USA
    BMC Genet 8:60. 2007
  4. ncbi request reprint Lifestyle determinants of high-density lipoprotein cholesterol: the National Heart, Lung, and Blood Institute Family Heart Study
    R Curtis Ellison
    Section of Preventive Medicine and Epidemiology, Evans Department of Medicine, Boston University School of Medicine, Boston, Mass 02118, USA
    Am Heart J 147:529-35. 2004
  5. ncbi request reprint Exploring the relation of alcohol consumption to risk of breast cancer
    R C Ellison
    Section of Preventive Medicine and Epidemiology, Evans Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA
    Am J Epidemiol 154:740-7. 2001
  6. ncbi request reprint Is alcohol consumption associated with calcified atherosclerotic plaque in the coronary arteries and aorta?
    R Curtis Ellison
    Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, MA 02118, USA
    Am Heart J 152:177-82. 2006
  7. ncbi request reprint Balancing the risks and benefits of moderate drinking
    R Curtis Ellison
    Department of Medicine, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    Ann N Y Acad Sci 957:1-6. 2002
  8. ncbi request reprint Relation of the metabolic syndrome to calcified atherosclerotic plaque in the coronary arteries and aorta
    R Curtis Ellison
    Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    Am J Cardiol 95:1180-6. 2005
  9. ncbi request reprint Lewis blood group phenotype as an independent risk factor for coronary heart disease (the NHLBI Family Heart Study)
    R C Ellison
    Evans Department of Medicine, Boston University School of Medicine, Massachusetts 02118, USA
    Am J Cardiol 83:345-8. 1999
  10. ncbi request reprint Influence of saturated fat and linolenic acid on the association between intake of dairy products and blood pressure
    Luc Djousse
    Division of Aging, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
    Hypertension 48:335-41. 2006

Research Grants

  1. HYPERGEN-BOSTON UNIVERSITY/FRAMINGHAM FIELD CENTER
    CURTIS ELLISON; Fiscal Year: 2004
  2. GENCAC - Framingham Field Center
    CURTIS ELLISON; Fiscal Year: 2004
  3. Net Lifetime Health Effects of Alcohol Use & Abuse
    CURTIS ELLISON; Fiscal Year: 2007

Collaborators

Detail Information

Publications72

  1. pmc Apolipoprotein ε4 polymorphism does not modify the association between body mass index and high-density lipoprotein cholesterol: a cross-sectional cohort study
    Catherine R Rahilly-Tierney
    Massachusetts Veterans Epidemiology and Information Research Center MAVERIC, Boston VA Healthcare, Boston, Massachusetts, USA
    Lipids Health Dis 10:167. 2011
    ....
  2. pmc Evidence for a gene influencing heart rate on chromosome 5p13-14 in a meta-analysis of genome-wide scans from the NHLBI Family Blood Pressure Program
    Jason M Laramie
    Department of Neurology, Boston University School of Medicine, Boston, MA, USA
    BMC Med Genet 7:17. 2006
    ..Previous family studies have shown a significant heritable component to heart rate with several groups conducting genomic linkage scans to identify quantitative trait loci...
  3. pmc An investigation of the effects of lipid-lowering medications: genome-wide linkage analysis of lipids in the HyperGEN study
    Jun Wu
    Division of Statistical Genomics, Washington University School of Medicine, Campus Box 8506, 4444 Forest Park Boulevard, Saint Louis, MO 63108, USA
    BMC Genet 8:60. 2007
    ..We propose an empirical method to adjust lipid levels for medication effects so that the adjusted lipid values substitute the unmedicated lipid values in the genetic analysis...
  4. ncbi request reprint Lifestyle determinants of high-density lipoprotein cholesterol: the National Heart, Lung, and Blood Institute Family Heart Study
    R Curtis Ellison
    Section of Preventive Medicine and Epidemiology, Evans Department of Medicine, Boston University School of Medicine, Boston, Mass 02118, USA
    Am Heart J 147:529-35. 2004
    ..While genetic factors are major determinants of high-density lipoprotein cholesterol (HDL-C), environmental factors also play a role. The latter include 3 modifiable lifestyle factors: alcohol consumption, physical activity, and smoking...
  5. ncbi request reprint Exploring the relation of alcohol consumption to risk of breast cancer
    R C Ellison
    Section of Preventive Medicine and Epidemiology, Evans Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA
    Am J Epidemiol 154:740-7. 2001
    ..Cohort studies with less than 10 years of follow-up gave estimates 11% higher than cohort studies with longer follow-up periods. No meaningful difference was seen by menopausal status or type of beverage consumed...
  6. ncbi request reprint Is alcohol consumption associated with calcified atherosclerotic plaque in the coronary arteries and aorta?
    R Curtis Ellison
    Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, MA 02118, USA
    Am Heart J 152:177-82. 2006
    ..Previous results have been conflicting, showing increases, decreases, or no effect of alcohol on risk of calcified plaque...
  7. ncbi request reprint Balancing the risks and benefits of moderate drinking
    R Curtis Ellison
    Department of Medicine, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    Ann N Y Acad Sci 957:1-6. 2002
    ..Thus, middle-aged or older men and post-menopausal women with no contraindications to alcohol use should be informed that they have, on average, net health benefits from the regular consumption of small-to-moderate amounts of alcohol...
  8. ncbi request reprint Relation of the metabolic syndrome to calcified atherosclerotic plaque in the coronary arteries and aorta
    R Curtis Ellison
    Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    Am J Cardiol 95:1180-6. 2005
    ..We conclude that the metabolic syndrome and most of its components are associated with a higher prevalence of calcified atherosclerotic plaque in the coronary arteries and abdominal aorta in white and African-American men and women...
  9. ncbi request reprint Lewis blood group phenotype as an independent risk factor for coronary heart disease (the NHLBI Family Heart Study)
    R C Ellison
    Evans Department of Medicine, Boston University School of Medicine, Massachusetts 02118, USA
    Am J Cardiol 83:345-8. 1999
    ..We conclude that the Le(a-b-) phenotype is associated with an increased risk for CHD; its effect does not appear to act predominantly through conventional cardiovascular risk factors. At present, mechanisms of effect are unknown...
  10. ncbi request reprint Influence of saturated fat and linolenic acid on the association between intake of dairy products and blood pressure
    Luc Djousse
    Division of Aging, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
    Hypertension 48:335-41. 2006
    ..This suggests that consumption of low-fat dairy products might be more beneficial for preventing HTN...
  11. ncbi request reprint Bone mass and the risk of colon cancer among postmenopausal women: the Framingham study
    Y Zhang
    Boston University Arthritis Center, Boston University School of Medicine, MA, USA
    Am J Epidemiol 153:31-7. 2001
    ..033). No association was found between bone mass and rectal cancer. The findings suggest that women with higher bone mass, perhaps reflecting greater cumulative estrogen exposure, have a decreased risk of colon cancer...
  12. ncbi request reprint Smoking influences the association between apolipoprotein E and lipids: the National Heart, Lung, and Blood Institute Family Heart Study
    L Djousse
    Section of Preventive Medicine and Epidemiology, Evans Department of Medicine, Boston University School of Medicine, Massachusetts 02118, USA
    Lipids 35:827-31. 2000
    ..Smoking may enhance genetic susceptibility to an unfavorable lipid profile among subjects with apo epsilon4...
  13. ncbi request reprint Risk profiles for non-communicable diseases in rural and urban schoolchildren in the Republic of Cameroon
    M H Proctor
    Evans Department of Medicine, Boston University School of Medicine 02118, USA
    Ethn Dis 6:235-43. 1996
    ....
  14. ncbi request reprint Relation between dietary fiber consumption and fibrinogen and plasminogen activator inhibitor type 1: The National Heart, Lung, and Blood Institute Family Heart Study
    L Djousse
    Evans Department of Medicine, Boston University School of Medicine, 02118, USA
    Am J Clin Nutr 68:568-75. 1998
    ..39 for men and 0.36 for women). These data suggest that higher fiber intake is inversely associated with PAI-1, but not with fibrinogen concentration...
  15. ncbi request reprint Adrenergic receptor polymorphisms associated with resting heart rate: the HyperGEN Study
    J B Wilk
    Boston University School of Medicine, MA 02118, USA
    Ann Hum Genet 70:566-73. 2006
    ..In summary, each of the ADR gene polymorphisms was associated with heart rate in at least one stratum studied, but there was no consistent association from which one would infer a large genetic contribution to heart rate...
  16. pmc Aminotransferase levels and 20-year risk of metabolic syndrome, diabetes, and cardiovascular disease
    Wolfram Goessling
    Division of Genetics and Gastroenterology, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Gastroenterology 135:1935-44, 1944.e1. 2008
    ..We studied the relationship between ALT levels and these disorders in a long-term follow-up study...
  17. ncbi request reprint BMI and waist circumference as predictors of lifetime colon cancer risk in Framingham Study adults
    L L Moore
    Boston University School of Medicine, Boston, MA 02118, USA
    Int J Obes Relat Metab Disord 28:559-67. 2004
    ..It is unclear whether the increased risk of colon cancer associated with obesity differs for men and women, by distribution of body fat, or by location of the tumor. The primary goal of this study was to address these questions...
  18. ncbi request reprint Alcohol consumption and risk of intermittent claudication in the Framingham Heart Study
    L Djousse
    Department of Medicine, Section of Preventive Medicine and Epidemiology Boston University School of Medicine, Boston, Massachusetts, USA
    Circulation 102:3092-7. 2000
    ..The purpose of this study was to assess the relation of alcohol consumption and type of beverage to the development of IC among participants in the Framingham Heart Study...
  19. ncbi request reprint Parental eating attitudes and the development of obesity in children. The Framingham Children's Study
    M Y Hood
    Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, MA 02118, USA
    Int J Obes Relat Metab Disord 24:1319-25. 2000
    ..To investigate the extent to which parents' degree of dietary self-control, as measured by self-reported dietary restraint, disinhibition, and perceived hunger, affects the development of excess body fat in the child...
  20. ncbi request reprint Relation between dietary linolenic acid and coronary artery disease in the National Heart, Lung, and Blood Institute Family Heart Study
    L Djousse
    Section of Preventive Medicine and Epidemiology, Evans Department of Medicine, The School of Medicine, Boston University, Boston, MA 02118, USA
    Am J Clin Nutr 74:612-9. 2001
    ..Studies in humans and animals also reported an inverse association between alpha-linolenic acid and cardiovascular disease morbidity and mortality...
  21. ncbi request reprint Acute effects of a high-fat meal with and without red wine on endothelial function in healthy subjects
    L Djousse
    Section of Preventive Medicine and Epidemiology, Evans Memorial Department of Medicine, Boston University School of Medicine, Massachusetts, USA
    Am J Cardiol 84:660-4. 1999
    ..Under these conditions, we did not demonstrate a beneficial acute effect of red wine on endothelial function...
  22. ncbi request reprint Dietary linolenic acid and fasting glucose and insulin: the National Heart, Lung, and Blood Institute Family Heart Study
    Luc Djousse
    Division of Aging, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
    Obesity (Silver Spring) 14:295-300. 2006
    ..To assess whether dietary linolenic acid is associated with fasting insulin and glucose...
  23. ncbi request reprint Sex-specific findings from a genome-wide linkage analysis of human fatness in non-Hispanic whites and African Americans: the HyperGEN study
    C E Lewis
    Division of Preventive Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35205, USA
    Int J Obes (Lond) 29:639-49. 2005
    ..To conduct a full genome search for genes potentially influencing two related phenotypes: body mass index (BMI, kg/m2) and percent body fat (PBF) from bioelectric impedance in men and women...
  24. ncbi request reprint Primary and subsequent coronary risk appraisal: new results from the Framingham study
    R B D'Agostino
    Department of Mathematics, College of Arts and Sciences, Boston University, MA 02215, USA
    Am Heart J 139:272-81. 2000
    ..The Framingham Heart Study has over the years produced mathematical "health risk appraisal models" that relate risk factors to the probability of developing CHD...
  25. ncbi request reprint Apolipoprotein E polymorphism modifies the alcohol-HDL association observed in the National Heart, Lung, and Blood Institute Family Heart Study
    Luc Djousse
    Section of Preventive Medicine and Epidemiology, Evans Department of Medicine, University of Minnesota, Minneapolis, USA
    Am J Clin Nutr 80:1639-44. 2004
    ....
  26. ncbi request reprint Intake of fruits, vegetables, and dairy products in early childhood and subsequent blood pressure change
    Lynn L Moore
    Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    Epidemiology 16:4-11. 2005
    ..Diets characterized by high intakes of fruits and vegetables and low-fat dairy products (for example, the DASH diet) have been shown to reduce blood pressure in adults. The effects of similar diets on children's blood pressure are unknown...
  27. ncbi request reprint Dietary linolenic acid is associated with a lower prevalence of hypertension in the NHLBI Family Heart Study
    Luc Djousse
    Section of Preventive Medicine and Epidemiology, Evans Department of Medicine, Boston University School of Medicine, Massachusetts 02118, USA
    Hypertension 45:368-73. 2005
    ..These data suggest that dietary linolenic acid is associated with a lower prevalence of hypertension and lower systolic blood pressure in white subjects...
  28. ncbi request reprint Alcohol consumption and metabolic syndrome: does the type of beverage matter?
    Luc Djousse
    Boston University School of Medicine, Room B 612, 715 Albany Street, Boston, Massachusetts 02118, USA
    Obes Res 12:1375-85. 2004
    ..To examine the association between total and beverage-specific alcohol consumption and the prevalence odds of metabolic syndrome (MS)...
  29. ncbi request reprint Alcohol consumption and the risk of bladder cancer in the Framingham Heart Study
    Luc Djousse
    Preventive Medicine and Epidemiology Section, Evans Department of Medicine, Boston University School of Medicine, Rm B 612, 715 Albany St, Boston, MA 02118, USA
    J Natl Cancer Inst 96:1397-400. 2004
    ..03), whereas wine (P(trend) =.7) and spirit (P(trend) =.2) consumption were not. Our data suggest that total and beverage-specific alcohol consumption are not associated with an increased risk of bladder cancer...
  30. pmc Serum urate is not associated with coronary artery calcification: the NHLBI Family Heart Study
    Tuhina Neogi
    Boston University School of Medicine, 650 Albany Street, Clin Epi Unit, Suite X 200, Boston, MA 02118, USA
    J Rheumatol 38:111-7. 2011
    ..Here, we examined whether SUA is associated with CAC, using the same study sample and methods as for our previous carotid atherosclerosis study...
  31. ncbi request reprint Dietary linolenic acid and adjusted QT and JT intervals in the National Heart, Lung, and Blood Institute Family Heart study
    Luc Djousse
    Section of Preventive Medicine and Epidemiology, Evans Department of Medicine, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    J Am Coll Cardiol 45:1716-22. 2005
    ..The goal of this study was to examine whether higher consumption of total linolenic acid was associated with rate-adjusted QT and JT intervals (QTrr and JTrr, respectively)...
  32. ncbi request reprint Dietary linolenic acid is inversely associated with calcified atherosclerotic plaque in the coronary arteries: the National Heart, Lung, and Blood Institute Family Heart Study
    Luc Djousse
    Evans Department of Medicine, Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, Mass 02118, USA
    Circulation 111:2921-6. 2005
    ..High dietary intake of linolenic acid is associated with a lower risk of cardiovascular disease mortality. However, little is known about the association between linolenic acid and subclinical atherosclerosis...
  33. ncbi request reprint Influence of alcohol dehydrogenase 1C polymorphism on the alcohol-cardiovascular disease association (from the Framingham Offspring Study)
    Luc Djousse
    Section of Preventive Medicine and Epidemiology, Evans Department of Medicine, Boston University, Boston, MA, USA
    Am J Cardiol 96:227-32. 2005
    ..The interaction does not appear to be mediated through effects on high-density lipoprotein cholesterol...
  34. ncbi request reprint Weight loss in overweight adults and the long-term risk of hypertension: the Framingham study
    Lynn L Moore
    Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, MA 02118, USA
    Arch Intern Med 165:1298-303. 2005
    ..Few studies address long-term effects of weight loss on risk of incident hypertension among overweight adults...
  35. pmc Secular trends in alcohol consumption over 50 years: the Framingham Study
    Yuqing Zhang
    Section of Preventive Medicine and Epidemiology, Evans Department of Medicine, Boston University School of Medicine and Boston Medical Center, MA 02118, USA
    Am J Med 121:695-701. 2008
    ..Population trends in patterns of alcohol use are important data for policymakers but are generally based on repeated cross-sectional surveys...
  36. pmc Serum uric acid is associated with carotid plaques: the National Heart, Lung, and Blood Institute Family Heart Study
    Tuhina Neogi
    Clinical Epidemiology Unit, Boston University School of Medicine, 650 Albany Street, Suite X 200, Boston, MA 02118, USA
    J Rheumatol 36:378-84. 2009
    ....
  37. ncbi request reprint Long-term alcohol consumption and the risk of atrial fibrillation in the Framingham Study
    Luc Djousse
    Section of Preventive Medicine and Epidemiology, Evans Department of Medicine, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    Am J Cardiol 93:710-3. 2004
    ..In conclusion, our data indicate little association between long-term moderate alcohol consumption and the risk of AF, but a significantly increased risk of AF among subjects consuming >36 g/day (approximatively >3 drinks/day)...
  38. ncbi request reprint Dietary linolenic acid and carotid atherosclerosis: the National Heart, Lung, and Blood Institute Family Heart Study
    Luc Djousse
    Section of Preventive Medicine and Epidemiology, Evans Department of Medicine, Boston University School of Medicine, MA 02118, USA
    Am J Clin Nutr 77:819-25. 2003
    ..Dietary intake of linolenic acid is associated with a lower risk of cardiovascular disease mortality. However, it is unknown whether linolenic acid is associated with a lower risk of carotid atherosclerosis...
  39. ncbi request reprint Effect of serum albumin and bilirubin on the risk of myocardial infarction (the Framingham Offspring Study)
    Luc Djousse
    The Department of Medicine, Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    Am J Cardiol 91:485-8. 2003
  40. ncbi request reprint Bone mass and the risk of prostate cancer: the Framingham Study
    Yuqing Zhang
    Clinical Epidemiology Research and Training Unit, Boston, University School of Medicine, Massachusetts 02118, USA
    Am J Med 113:734-9. 2002
    ..To examine the relation of bone mass-a potential biologic marker for cumulative exposure to androgens, insulin-like growth factors, and calcium intake-to subsequent development of prostate cancer...
  41. ncbi request reprint Relation between serum albumin and carotid atherosclerosis: the NHLBI Family Heart Study
    Luc Djousse
    Evans Department of Medicine, Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, Mass 02118, USA
    Stroke 34:53-7. 2003
    ..Lower concentrations of albumin have been positively related to coronary disease. The aim of this project was to assess the association between serum albumin and carotid atherosclerosis...
  42. ncbi request reprint Alcohol consumption and risk of lung cancer: the Framingham Study
    Luc Djousse
    Section of Preventive Medicine and Epidemiology, Evans Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA
    J Natl Cancer Inst 94:1877-82. 2002
    ..Reports on the association between alcohol consumption and the risk of lung cancer have been inconsistent. The purpose of this study was to assess this association in a cohort study...
  43. ncbi request reprint Serum albumin and risk of myocardial infarction and all-cause mortality in the Framingham Offspring Study
    Luc Djousse
    Department of Medicine, Boston University School of Medicine, Boston, Mass 02118, USA
    Circulation 106:2919-24. 2002
    ....
  44. ncbi request reprint Evidence for a gene influencing heart rate on chromosome 4 among hypertensives
    Jemma B Wilk
    Contact address Boston University School of Medicine, 715 Albany Street, Room B 604, Boston, MA 02118, USA
    Hum Genet 111:207-13. 2002
    ....
  45. ncbi request reprint Influence of apolipoprotein E, smoking, and alcohol intake on carotid atherosclerosis: National Heart, Lung, and Blood Institute Family Heart Study
    Luc Djousse
    Section of Preventive Medicine and Epidemiology, Evans Department of Medicine, Boston University School of Medicine, Boston, Mass 02118, USA
    Stroke 33:1357-61. 2002
    ..Apolipoprotein E (apoE) isoforms and lifestyle factors play an important role in the development of coronary heart disease. The association of apoE and carotid atherosclerosis remains controversial...
  46. ncbi request reprint Alcohol consumption and risk of ischemic stroke: The Framingham Study
    Luc Djousse
    Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, MA 02118, USA
    Stroke 33:907-12. 2002
    ..Stroke is a major cause of death in the United States. The association between alcohol consumption and ischemic stroke (IS) remains controversial...
  47. ncbi request reprint Does early physical activity predict body fat change throughout childhood?
    Lynn L Moore
    Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, MA 02118, USA
    Prev Med 37:10-7. 2003
    ..Studies to date, however, have not consistently demonstrated such a protective effect. We used longitudinal data from the Framingham Children's Study (FCS) to address this important question...
  48. ncbi request reprint Fruit and vegetable consumption and LDL cholesterol: the National Heart, Lung, and Blood Institute Family Heart Study
    Luc Djousse
    Section of Preventive Medicine and Epidemiology, Evans Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA
    Am J Clin Nutr 79:213-7. 2004
    ..An elevated LDL-cholesterol concentration is associated with an increased risk of cardiovascular disease. The association between fruit and vegetable consumption and LDL has been inconsistent...
  49. ncbi request reprint Dietary linolenic acid is inversely associated with plasma triacylglycerol: the National Heart, Lung, and Blood Institute Family Heart Study
    Luc Djousse
    Section of Preventive Medicine and Epidemiology, Evans Department of Medicine, Boston University School of Medicine, Room B 612, 715 Albany Street, Boston, MA 02118, USA
    Am J Clin Nutr 78:1098-102. 2003
    ..Dietary intake of linolenic acid is associated with a decreased risk of cardiovascular disease mortality. However, the mechanisms by which dietary linolenic acid affects cardiovascular disease risk are not clearly understood...
  50. ncbi request reprint The feasibility of using rural health workers to determine cause of death in remote regions of Cameroon, West Africa
    M H Proctor
    Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    Ethn Dis 11:701-10. 2001
    ..In 70% of the cases the physician and HW were in exact agreement. Such a method, if confirmed in other studies among rural populations, may be an important approach to determining cause of death in many developing countries...
  51. pmc Common variants in the 5' region of the leptin gene are associated with body mass index in men from the National Heart, Lung, and Blood Institute Family Heart Study
    Y Jiang
    Department of Neurology, Evans Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA
    Am J Hum Genet 75:220-30. 2004
    ..00005). All five of these SNPs are predicted to modify transcription-factor binding sites. This may indicate new functional variants in an extended promoter region of LEP...
  52. ncbi request reprint Alcohol consumption and hemostatic factors: analysis of the Framingham Offspring cohort
    K J Mukamal
    Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Circulation 104:1367-73. 2001
    ..Moderate alcohol consumers have lower rates of cardiovascular disease than abstainers. One proposed mechanism is a beneficial effect on hemostatic parameters, but previous studies have provided conflicting results...
  53. ncbi request reprint Bone mineral density and verbal memory impairment: Third National Health and Nutrition Examination Survey
    Y Zhang
    Boston University Arthritis Center, Boston University School of Medicine, Boston, MA 02115, USA
    Am J Epidemiol 154:795-802. 2001
    ..001). These results suggest that bone mineral density in the elderly is associated with verbal memory impairment. The mechanisms underlying this relation are not understood, but cumulative exposure to estrogen may play a role...
  54. pmc Fucosyltransferase 3 polymorphism and atherothrombotic disease in the Framingham Offspring Study
    Luc Djousse
    Division of Aging, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    Am Heart J 153:636-9. 2007
    ..Previous studies have suggested a positive association between phenotypes of fucosyltransferase 3 (FUT3) gene (also known as Lewis gene) and coronary heart disease...
  55. ncbi request reprint Effects of polymorphisms of methionine synthase and methionine synthase reductase on total plasma homocysteine in the NHLBI Family Heart Study
    Paul F Jacques
    Jean Mayer USDA, Human Nutrition Research Center on Aging at Tufts University, 711 Wasington Street, Boston, MA 02111, USA
    Atherosclerosis 166:49-55. 2003
    ..This study provides no evidence that these common MTR and MTRR mutations are associated with alterations in plasma homocysteine...
  56. ncbi request reprint Television viewing and change in body fat from preschool to early adolescence: The Framingham Children's Study
    M H Proctor
    Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, MA 02118, USA
    Int J Obes Relat Metab Disord 27:827-33. 2003
    ..To prospectively examine the relation between television watching and body fat change in children from preschool to early adolescence...
  57. pmc Parental obesity and offspring serum alanine and aspartate aminotransferase levels: the Framingham heart study
    Rohit Loomba
    Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland
    Gastroenterology 134:953-9. 2008
    ..We sought to examine the relations between parental obesity and the serum ALT and AST levels among offspring in a community-based sample...
  58. ncbi request reprint Genome scans for blood pressure and hypertension: the National Heart, Lung, and Blood Institute Family Heart Study
    Steven C Hunt
    Cardiovascular Genetics Program, Cardiology Division, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah, USA
    Hypertension 40:1-6. 2002
    ..These results overlap other published scans, particularly regions on chromosomes 1 and 6, which have been implicated in familial combined hyperlipidemia...
  59. ncbi request reprint Alcohol consumption and risk for congestive heart failure in the Framingham Heart Study
    Craig R Walsh
    National Heart, Lung, and Blood Institute s Framingham Heart Study, National Institutes of Health, Framingham, Massachusetts 01702, USA
    Ann Intern Med 136:181-91. 2002
    ..Although excessive alcohol consumption can promote cardiomyopathy, little is known about the association between alcohol consumption and risk for congestive heart failure in the community...
  60. ncbi request reprint Segregation analysis of HDL cholesterol in the NHLBI Family Heart Study and in Utah pedigrees
    Florian Kronenberg
    Department of Cardiovascular Genetics, University of Utah, Salt Lake City, Utah, USA
    Eur J Hum Genet 10:367-74. 2002
    ..Instead we found some evidence for the segregation of an allele associated with high HDL-C. d..
  61. ncbi request reprint Association of coronary artery calcified plaque with clinical coronary heart disease in the National Heart, Lung, and Blood Institute's Family Heart Study
    Paul N Hopkins
    Cardiovascular Genetics Research, University of Utah, Salt Lake City, Utah, USA
    Am J Cardiol 97:1564-9. 2006
    ..In conclusion, CAC was strongly associated with CHD even after adjustment for standard risk factors and family history contributed independently to CHD risk...
  62. ncbi request reprint Genome-wide linkage analysis replicates susceptibility locus for fasting plasma triglycerides: NHLBI Family Heart Study
    Donna K Arnett
    Division of Epidemiology, University of Minnesota, 1300 South Second Street, Suite 300, Minneapolis, MN 55454, USA
    Hum Genet 115:468-74. 2004
    ..Chromosome 15 likely harbors a susceptibility locus with an influence on triglycerides and HDL. Regions on chromosomes 6 and 8 may also contain loci contributing to inter-individual variation in plasma triglycerides...
  63. ncbi request reprint Coronary artery disease risk in familial combined hyperlipidemia and familial hypertriglyceridemia: a case-control comparison from the National Heart, Lung, and Blood Institute Family Heart Study
    Paul N Hopkins
    Cardiovascular Genetics Research, University of Utah, Salt Lake City, USA
    Circulation 108:519-23. 2003
    ..However, no population-based studies have critically addressed this issue...
  64. ncbi request reprint Age dependence of the influence of methylenetetrahydrofolate reductase genotype on plasma homocysteine level
    Loretta D Spotila
    Department of Bioscience and Biotechnology, College of Arts and Sciences, Drexel University, Philadelphia, PA, USA
    Am J Epidemiol 158:871-7. 2003
    ..Failure to examine younger patients separately may explain why some studies have found no association between the genotype and cardiovascular disease...
  65. ncbi request reprint Interarm differences in seated systolic and diastolic blood pressure: the Hypertension Genetic Epidemiology Network study
    Donna K Arnett
    University of Alabama at Birmingham, School of Public Health, Department of Epidemiology, Birmingham, Alabama 55294 0022, USA
    J Hypertens 23:1141-7. 2005
    ..To examine whether blood pressure (BP) differs between arms in hypertensive siblings and randomly selected volunteers, and whether this difference is explained by cardiovascular risk factors...
  66. ncbi request reprint Hostility and physiological risk in the National Heart, Lung, and Blood Institute Family Heart Study
    Sarah S Knox
    Division of Epidemiology, Statistics, and Prevention Research, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA
    Arch Intern Med 164:2442-8. 2004
    ..The present analyses investigated possible pathways for earlier reported associations in the National Heart, Lung, and Blood Institute Family Heart Study between hostility and coronary and carotid end points...
  67. ncbi request reprint A summary of the effects of antihypertensive medications on measured blood pressure
    Jun Wu
    Division of Biostatistics, Washington University School of Medicine, Saint Louis, Missouri 63110 1093, USA
    Am J Hypertens 18:935-42. 2005
    ..A review of numerous clinical trials that investigated the effects of BP-lowering medications is summarized here...
  68. ncbi request reprint Importance of pattern of alcohol consumption
    R Curtis Ellison
    Circulation 112:3818-9. 2005
  69. ncbi request reprint Evidence for a gene influencing fasting LDL cholesterol and triglyceride levels on chromosome 21q
    Kari E North
    Department of Epidemiology, University of North Carolina, Bank of America Center, 137 E Franklin St, Suite 306, Chapel Hill, NC 27514, USA
    Atherosclerosis 179:119-25. 2005
    ....
  70. ncbi request reprint Positional identification of hypertension susceptibility genes on chromosome 2
    Ruth Ann Barkley
    Human Genetics Center and Institute of Molecular Medicine, of Texas Health Science Center at Houston, USA
    Hypertension 43:477-82. 2004
    ..Moreover, the present study validates previous evidence for one or more genes on chromosome 2 that influence hypertension-related phenotypes in the population-at-large...
  71. ncbi request reprint Familial aggregation and genome-wide linkage analysis of carotid artery plaque: the NHLBI family heart study
    James S Pankow
    Division of Epidemiology, University of Minnesota, 1300 South Second Street, Ste 300, Minneapolis, MN 55454, USA
    Hum Hered 57:80-9. 2004
    ..To evaluate familial and genetic influences on carotid artery plaque, a qualitative marker of the systemic burden of atherosclerosis...
  72. ncbi request reprint Cardiovascular risk factors and confounders among nondrinking and moderate-drinking U.S. adults
    R Curtis Ellison
    Am J Prev Med 29:243; author reply 243-4. 2005

Research Grants7

  1. HYPERGEN-BOSTON UNIVERSITY/FRAMINGHAM FIELD CENTER
    CURTIS ELLISON; Fiscal Year: 2004
    ..The resulting synthesis of ideas and amassed data permits rigorous hypothesis testing not otherwise possible and will hasten understanding of the previously elusive genetic variation responsible for disease risk. ..
  2. GENCAC - Framingham Field Center
    CURTIS ELLISON; Fiscal Year: 2004
    ..abstract_text> ..
  3. Net Lifetime Health Effects of Alcohol Use & Abuse
    CURTIS ELLISON; Fiscal Year: 2007
    ..The study will produce a unique dataset and will provide information that should improve our knowledge of the net effects of alcohol throughout adult life. ..