Daniel J Dwyer

Summary

Affiliation: Boston University
Country: USA

Publications

  1. pmc Role of reactive oxygen species in antibiotic action and resistance
    Daniel J Dwyer
    Howard Hughes Medical Institute, Department of Biomedical Engineering, Center for BioDynamics and Center for Advanced Biotechnology, Boston University, 44 Cummington Street, Boston, MA 02215, USA
    Curr Opin Microbiol 12:482-9. 2009
  2. pmc Mistranslation of membrane proteins and two-component system activation trigger antibiotic-mediated cell death
    Michael A Kohanski
    Department of Biomedical Engineering, Center for BioDynamics, and Center for Advanced Biotechnology, Boston University, Boston, MA 02215, USA
    Cell 135:679-90. 2008
  3. pmc Antibiotic-induced bacterial cell death exhibits physiological and biochemical hallmarks of apoptosis
    Daniel J Dwyer
    Howard Hughes Medical Institute, Boston University, Boston, MA 02215, USA
    Mol Cell 46:561-72. 2012
  4. ncbi request reprint A common mechanism of cellular death induced by bactericidal antibiotics
    Michael A Kohanski
    Center for BioDynamics and Center for Advanced Biotechnology, Boston University, Boston, MA 02215, USA
    Cell 130:797-810. 2007
  5. pmc How antibiotics kill bacteria: from targets to networks
    Michael A Kohanski
    Howard Hughes Medical Institute and the Department of Biomedical Engineering, Center for BioDynamics and Center for Advanced Biotechnology, Boston University, 44 Cummington Street, Boston, Massachusetts 02215, USA
    Nat Rev Microbiol 8:423-35. 2010
  6. pmc Gyrase inhibitors induce an oxidative damage cellular death pathway in Escherichia coli
    Daniel J Dwyer
    Program in Molecular Biology, Cell Biology and Biochemistry, Boston University, Boston, MA 02215, USA
    Mol Syst Biol 3:91. 2007
  7. pmc Networking opportunities for bacteria
    Daniel J Dwyer
    Howard Hughes Medical Institute, Center for BioDynamics, Center for Advanced Biotechnology, Boston University, Boston, MA 02215, USA
    Cell 135:1153-6. 2008
  8. pmc Tracking, tuning, and terminating microbial physiology using synthetic riboregulators
    Jarred M Callura
    Howard Hughes Medical Institute, Boston University, MA 02215, USA
    Proc Natl Acad Sci U S A 107:15898-903. 2010

Collaborators

Detail Information

Publications8

  1. pmc Role of reactive oxygen species in antibiotic action and resistance
    Daniel J Dwyer
    Howard Hughes Medical Institute, Department of Biomedical Engineering, Center for BioDynamics and Center for Advanced Biotechnology, Boston University, 44 Cummington Street, Boston, MA 02215, USA
    Curr Opin Microbiol 12:482-9. 2009
    ..Additionally, we describe ways in which these responses are being taken advantage to combat bacterial infections and arrest the rise of resistant strains...
  2. pmc Mistranslation of membrane proteins and two-component system activation trigger antibiotic-mediated cell death
    Michael A Kohanski
    Department of Biomedical Engineering, Center for BioDynamics, and Center for Advanced Biotechnology, Boston University, Boston, MA 02215, USA
    Cell 135:679-90. 2008
    ....
  3. pmc Antibiotic-induced bacterial cell death exhibits physiological and biochemical hallmarks of apoptosis
    Daniel J Dwyer
    Howard Hughes Medical Institute, Boston University, Boston, MA 02215, USA
    Mol Cell 46:561-72. 2012
    ....
  4. ncbi request reprint A common mechanism of cellular death induced by bactericidal antibiotics
    Michael A Kohanski
    Center for BioDynamics and Center for Advanced Biotechnology, Boston University, Boston, MA 02215, USA
    Cell 130:797-810. 2007
    ..g., reca...
  5. pmc How antibiotics kill bacteria: from targets to networks
    Michael A Kohanski
    Howard Hughes Medical Institute and the Department of Biomedical Engineering, Center for BioDynamics and Center for Advanced Biotechnology, Boston University, 44 Cummington Street, Boston, Massachusetts 02215, USA
    Nat Rev Microbiol 8:423-35. 2010
    ....
  6. pmc Gyrase inhibitors induce an oxidative damage cellular death pathway in Escherichia coli
    Daniel J Dwyer
    Program in Molecular Biology, Cell Biology and Biochemistry, Boston University, Boston, MA 02215, USA
    Mol Syst Biol 3:91. 2007
    ..Together, this series of biochemical reactions appears to compose a maladaptive response, that serves to amplify the primary effect of gyrase inhibition by oxidatively damaging DNA, proteins and lipids...
  7. pmc Networking opportunities for bacteria
    Daniel J Dwyer
    Howard Hughes Medical Institute, Center for BioDynamics, Center for Advanced Biotechnology, Boston University, Boston, MA 02215, USA
    Cell 135:1153-6. 2008
    ..Here, we highlight recent systems biology studies in prokaryotes, consider the challenges ahead, and suggest opportunities for future studies in bacterial models...
  8. pmc Tracking, tuning, and terminating microbial physiology using synthetic riboregulators
    Jarred M Callura
    Howard Hughes Medical Institute, Boston University, MA 02215, USA
    Proc Natl Acad Sci U S A 107:15898-903. 2010
    ..This work establishes a broad, easy-to-use synthetic biology platform for microbiology experiments and biotechnology applications...