Genomes and Genes


Josee Dupuis


Affiliation: Boston University
Country: USA


  1. Hansen J, Gao W, Dupuis J, O Connor G, Tang W, Kowgier M, et al. Association of 25-Hydroxyvitamin D status and genetic variation in the vitamin D metabolic pathway with FEV1 in the Framingham Heart Study. Respir Res. 2015;16:81 pubmed publisher
    ..The inconsistent associations may be driven by differences in the groups studied. CYP2R1 demonstrated a gene-based association with longitudinal change in FEV1 and is a promising candidate gene for further studies. ..
  2. KLIMENT C, Araki T, Doyle T, Gao W, Dupuis J, Latourelle J, et al. A comparison of visual and quantitative methods to identify interstitial lung abnormalities. BMC Pulm Med. 2015;15:134 pubmed publisher
    ..Moreover, HAAs were not associated with MUC5B promoter genotype. ..
  3. Kraja A, Chasman D, North K, Reiner A, Yanek L, Kilpeläinen T, et al. Pleiotropic genes for metabolic syndrome and inflammation. Mol Genet Metab. 2014;112:317-38 pubmed publisher
    ..These findings warrant further functional investigation. ..
  4. Xing C, Dupuis J, Cupples L. Performance of statistical methods on CHARGE targeted sequencing data. BMC Genet. 2014;15:104 pubmed publisher
    ..Greater numbers of causal variants and a greater proportion of variance improve the power, but it tends to be lower in the presence of bi-directionality of effects of causal genotypes, especially for Score-Seq. ..