Rutao Cui

Summary

Affiliation: Boston University
Country: USA

Publications

  1. pmc FGF2 regulates melanocytes viability through the STAT3-transactivated PAX3 transcription
    L Dong
    Department of Dermatology, Boston University School of Medicine, 609 Albany Street, Boston, MA 02118, USA
    Cell Death Differ 19:616-22. 2012
  2. pmc Central role of cellular senescence in TSLP-induced airway remodeling in asthma
    Jinxiang Wu
    Department of Respiratory, Qilu Hospital of Shandong University, Jinan, Shandong, China
    PLoS ONE 8:e77795. 2013
  3. doi request reprint Stat3-targeted therapies overcome the acquired resistance to vemurafenib in melanomas
    Fang Liu
    Department of Dermatology, Boston University School of Medicine, Boston, Massachusetts 02478, USA
    J Invest Dermatol 133:2041-9. 2013
  4. pmc TBX2 expression is regulated by PAX3 in the melanocyte lineage
    Fang Liu
    Department of Dermatology, Boston University School of Medicine, Boston, MA, USA
    Pigment Cell Melanoma Res 26:67-77. 2013
  5. pmc MC1R is a potent regulator of PTEN after UV exposure in melanocytes
    Juxiang Cao
    Department of Dermatology, Boston University School of Medicine, 609 Albany Street, Boston, MA 02118, USA
    Mol Cell 51:409-22. 2013
  6. doi request reprint Inhibition of PAX3 by TGF-beta modulates melanocyte viability
    Guang Yang
    Department of Medical Oncology, Dana Farber Cancer Institute, Children s Hospital Boston, Harvard Medical School, 44 Binney Street, Boston, MA 02115, USA
    Mol Cell 32:554-63. 2008
  7. ncbi request reprint Central role of p53 in the suntan response and pathologic hyperpigmentation
    Rutao Cui
    Melanoma Program in Medical Oncology, Dana Farber Cancer Institute, Harvard Medical School, 44 Binney Street, Boston, MA 02115, USA
    Cell 128:853-64. 2007
  8. pmc PGC-1 coactivators regulate MITF and the tanning response
    Jonathan Shoag
    Cardiovascular Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA
    Mol Cell 49:145-57. 2013
  9. pmc Loss of ARF sensitizes transgenic BRAFV600E mice to UV-induced melanoma via suppression of XPC
    Chi Luo
    Graduate Program in Genetics, Sackler School of Graduate Biomedical Sciences, Tufts University, Boston, Massachusetts, USA
    Cancer Res 73:4337-48. 2013
  10. ncbi request reprint Protein kinase Cδ is a therapeutic target in malignant melanoma with NRAS mutation
    Asami Takashima
    Cancer Center, Departments of Medicine, Biochemistry, Pediatrics, Microbiology, Pathology and Laboratory Medicine, and Department of Dermatology, Boston University School of Medicine, 72 E Concord Street, Boston, Massachusetts 02118, United States
    ACS Chem Biol 9:1003-14. 2014

Research Grants

Collaborators

Detail Information

Publications10

  1. pmc FGF2 regulates melanocytes viability through the STAT3-transactivated PAX3 transcription
    L Dong
    Department of Dermatology, Boston University School of Medicine, 609 Albany Street, Boston, MA 02118, USA
    Cell Death Differ 19:616-22. 2012
    ..Moreover, our results suggest that this pathway might contribute to the regulation of melanocyte numbers and melanin levels, and thereby provide an alternative strategy to induce pigmentation...
  2. pmc Central role of cellular senescence in TSLP-induced airway remodeling in asthma
    Jinxiang Wu
    Department of Respiratory, Qilu Hospital of Shandong University, Jinan, Shandong, China
    PLoS ONE 8:e77795. 2013
    ..Thymic stromal lymphopoietin (TSLP), a vital cytokine, plays a critical role in orchestrating, perpetuating and amplifying the inflammatory response in asthma. TSLP is also a critical factor in airway remodeling in asthma...
  3. doi request reprint Stat3-targeted therapies overcome the acquired resistance to vemurafenib in melanomas
    Fang Liu
    Department of Dermatology, Boston University School of Medicine, Boston, Massachusetts 02478, USA
    J Invest Dermatol 133:2041-9. 2013
    ..Our results suggest that Stat3-targeted therapy is a new therapeutic strategy to overcome the acquired resistance to vemurafenib in the treatment of melanoma...
  4. pmc TBX2 expression is regulated by PAX3 in the melanocyte lineage
    Fang Liu
    Department of Dermatology, Boston University School of Medicine, Boston, MA, USA
    Pigment Cell Melanoma Res 26:67-77. 2013
    ....
  5. pmc MC1R is a potent regulator of PTEN after UV exposure in melanocytes
    Juxiang Cao
    Department of Dermatology, Boston University School of Medicine, 609 Albany Street, Boston, MA 02118, USA
    Mol Cell 51:409-22. 2013
    ..These studies establish the MC1R-PTEN axis as a central regulator for melanocytes' response to UVB exposure and reveal the molecular basis underlying the association between MC1R variants and melanomagenesis. ..
  6. doi request reprint Inhibition of PAX3 by TGF-beta modulates melanocyte viability
    Guang Yang
    Department of Medical Oncology, Dana Farber Cancer Institute, Children s Hospital Boston, Harvard Medical School, 44 Binney Street, Boston, MA 02115, USA
    Mol Cell 32:554-63. 2008
    ....
  7. ncbi request reprint Central role of p53 in the suntan response and pathologic hyperpigmentation
    Rutao Cui
    Melanoma Program in Medical Oncology, Dana Farber Cancer Institute, Harvard Medical School, 44 Binney Street, Boston, MA 02115, USA
    Cell 128:853-64. 2007
    ..p53 thus functions as a sensor/effector for UV pigmentation, which is a nearly constant environmental exposure. Moreover, this pathway is activated in numerous conditions of pathologic pigmentation and thus mimics the tanning response...
  8. pmc PGC-1 coactivators regulate MITF and the tanning response
    Jonathan Shoag
    Cardiovascular Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA
    Mol Cell 49:145-57. 2013
    ..These data identify PGC-1 coactivators as regulators of human tanning...
  9. pmc Loss of ARF sensitizes transgenic BRAFV600E mice to UV-induced melanoma via suppression of XPC
    Chi Luo
    Graduate Program in Genetics, Sackler School of Graduate Biomedical Sciences, Tufts University, Boston, Massachusetts, USA
    Cancer Res 73:4337-48. 2013
    ..We suggest that the deletion of ARF promotes melanomagenesis not by abrogating p53 activation but by acting in concert with BRAF(V600E) to increase the load of DNA damage caused by UVR...
  10. ncbi request reprint Protein kinase Cδ is a therapeutic target in malignant melanoma with NRAS mutation
    Asami Takashima
    Cancer Center, Departments of Medicine, Biochemistry, Pediatrics, Microbiology, Pathology and Laboratory Medicine, and Department of Dermatology, Boston University School of Medicine, 72 E Concord Street, Boston, Massachusetts 02118, United States
    ACS Chem Biol 9:1003-14. 2014
    ....

Research Grants2

  1. The role of pheomelanin in cutaneous melanoma
    Rutao Cui; Fiscal Year: 2010
    ..Our results may provide a rich framework for melanoma prevention;and development of targeted small-molecules to induce eumelanin (black/brown), and hence an eventual reduction in incidence of this widely lethal malignancy. ..
  2. The role of pheomelanin in cutaneous melanoma
    Rutao Cui; Fiscal Year: 2009
    ..Our results may provide a rich framework for melanoma prevention; and development of targeted small-molecules to induce eumelanin (black/brown), and hence an eventual reduction in incidence of this widely lethal malignancy. ..