Research Topics
| J A ClarkSummaryAffiliation: Boston University Country: USA Publications
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Publications
Measuring perceived effects of drinking an extract of basidiomycetes Agaricus blazei Murill: a survey of Japanese consumers with cancerJames A Talcott
Center for Outcomes Research, Massachusetts General Hospital Cancer Center and Harvard Medical School, Boston, MA, USA
BMC Complement Altern Med 7:32. 2007..To survey cancer patients who consume an extract of the Basidiomycetes Agaricus blazei Murill mushroom (Sen-Sei-Ro) to measure their self-assessment of its effects and to develop an instrument for use in future randomized trials...
Confidence and uncertainty long after initial treatment for early prostate cancer: survivors' views of cancer control and the treatment decisions they madeJack A Clark
Center for Health Quality, Outcomes, and Economic Research, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, USA
J Clin Oncol 24:4457-63. 2006..The many years most men diagnosed with early prostate cancer live after diagnosis allow evolving assessments of their cancer control and their treatment choices, but little is known of these outcomes or the factors that influence them...
Patient-based measures of illness severity in the Veterans Health StudyJack A Clark
Department of Health Services, Boston University School of Public Health, Massachusetts 02118, USA
J Ambul Care Manage 28:274-85. 2005..The 6 measures may complement measures of health-related quality of life in providing more comprehensive assessments of health status in Veterans Affairs patients...
Patients' perceptions of quality of life after treatment for early prostate cancerJack A Clark
Department of Health Services, Boston University School of Public Health, Boston, MA 02118, USA
J Clin Oncol 21:3777-84. 2003..Treatment for early prostate cancer produces problematic physical side effects, but prior studies have found little influence on patients' perceived health status. We examined psychosocial outcomes of treatment for early prostate cancer...
Measuring patients' perceptions of the outcomes of treatment for early prostate cancerJack A Clark
Health Services Department, Boston University School of Public Health, and Center for Health Quality, Outcomes, and Economic Research, Edith Nourse Rogers Memorial Veterans Hospital Bedford, Boston, Massachusetts 02118, USA
Med Care 41:923-36. 2003....
Symptom indexes to assess outcomes of treatment for early prostate cancerJ A Clark
Center for Health Quality, Outcomes, and Economic Research, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, MA 01730, USA
Med Care 39:1118-30. 2001..Patients' perceptions of treatment outcomes are important in the management of early prostate cancer, but few studies have offered reliable and responsive measures to assess the likely side effects of the most common treatments...
Living with treatment decisions: regrets and quality of life among men treated for metastatic prostate cancerJ A Clark
Center for Health Quality, Outcomes and Economic Research, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, MA 01730, USA
J Clin Oncol 19:72-80. 2001..To examine variation in men's long-term regret of treatment decisions, ie, surgical versus chemical castration, for metastatic prostate cancer and its associations with quality of life...
Complications after treatment with external-beam irradiation in early-stage prostate cancer patients: a prospective multiinstitutional outcomes studyC J Beard
Joint Center for Radiation Therapy, Boston, MA 02115, USA
J Clin Oncol 15:223-9. 1997..To use data from a prospective quality-of-life study to assess differences in disease-specific and general health-related quality-of-life changes after treatment with different external-beam irradiation techniques for prostate cancer...
Patient-reported symptoms after primary therapy for early prostate cancer: results of a prospective cohort studyJ A Talcott
Dana Farber Cancer Institute, Brigham and Women s Hospital, Boston, MA, USA
J Clin Oncol 16:275-83. 1998..To assess complications of therapy for early (nonmetastatic) prostate cancer...
Hidden barriers between knowledge and behavior: the North Carolina prostate cancer screening and treatment experienceJames A Talcott
Center for Outcomes Research, Massachusetts General Hospital Cancer Center and Harvard Medical School, Boston, Massachusetts 02114, USA
Cancer 109:1599-606. 2007..To identify patient factors that might account for some of this disparity, men within 6 months of diagnosis were surveyed about health attitudes and behavior...
Time course and predictors of symptoms after primary prostate cancer therapyJames A Talcott
Center for Outcomes Research, MGH Cancer Center, Massachusetts General Hospital, Boston, 02114 2696, USA
J Clin Oncol 21:3979-86. 2003..We characterized the time course of treatment complications while adjusting for potentially confounding pretreatment factors hindering other observational studies...
Treatment 'mismatch' in early prostate cancer: do treatment choices take patient quality of life into account?Ronald C Chen
Center for Outcomes Research, MGH Cancer Center, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Cancer 112:61-8. 2008..Using patient-reported baseline dysfunction from a prospective cohort study, we determined the proportion of patients receiving relatively contraindicated ('mismatched') treatments...
Patient-reported quality of life after salvage brachytherapy for radio-recurrent prostate cancer: A prospective Phase II studyPaul L Nguyen
Harvard Radiation Oncology Program, Boston, MA 02115, USA
Brachytherapy 8:345-52. 2009..Patient-reported quality of life (QOL) after salvage brachytherapy for radiorecurrent prostate cancer has not been well-characterized prospectively...
Married couples' perspectives on prostate cancer diagnosis and treatment decision-makingU Boehmer
School of Public Health, Boston University, Boston, MA, USA
Psychooncology 10:147-55. 2001..Our findings suggest that physicians may be in a position to influence how men and their wives interact in reaching a treatment decision...
Sexuality after treatment for early prostate cancer: exploring the meanings of "erectile dysfunction"B G Bokhour
Center for Health Quality, Outcomes, and Economic Research, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, MA 01730, USA
J Gen Intern Med 16:649-55. 2001..To explore perceptions of the impact of erectile dysfunction on men who had undergone definitive treatment for early nonmetastatic prostate cancer...
No less a man: reconstructing identity after prostate cancerBarbara G Bokhour
ENRM Veterans Hospital, MA 01730, USA
Commun Med 4:99-109. 2007..We argue that these men draw upon alternative discourses to construct themselves as whole, competent, and 'no less a man'...
Patient navigation: development of a protocol for describing what navigators doVictoria A Parker
Department of Health Policy and Management, Boston University School of Public Health, 715 Albany St T3W, Boston, MA 02118 2526, USA
Health Serv Res 45:514-31. 2010..To develop a structured protocol for observing patient navigators at work, describing and characterizing specific activities related to their goals...
Applications of methodologies of the Veterans Health Study in the VA healthcare system: conclusions and summaryLewis E Kazis
Center for Health Quality, Outcomes, and Economic Research CHQOER, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, Mass 01730, USA
J Ambul Care Manage 29:182-8. 2006..Based upon the rich foundation provided by the VHS methodology, the VA has implemented some of these approaches as part of its quality monitoring system and can serve as a model for other large integrated systems of care...
Assessment of long-term complications due to type 2 diabetes using patient self-report: the diabetes complications indexB Graeme Fincke
Center for Health Quality, Outcomes and Economic Research CHQOER, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, Massachusetts 01730, USA
J Ambul Care Manage 28:262-73. 2005..23, P = .0001). The DCI shows promise as an efficient method for assessing the effects of type 2 diabetes on HRQOL and predicting utilization of medical resources...
The influence of place of administration on health-related quality-of-life assessments: findings from the Veterans Health StudyDonald R Miller
Center for Health Quality, Outcomes, and Economics Research CHQOER, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, MA 01730, USA
J Ambul Care Manage 28:111-24. 2005..Findings from this study suggest that more favorable measures of self-reported functional status and well-being may be expected from clinic administrations of instruments...
Why do low-income minority parents choose human papillomavirus vaccination for their daughters?Rebecca B Perkins
Department of Obstetrics and Gynecology, Boston University School of Medicine, Boston, MA 02118, USA
J Pediatr 157:617-22. 2010..To explore low-income minority parents' attitudes, intentions, and actions with regard to human papillomavirus (HPV) vaccination for their daughters...
Racial differences in health-related beliefs, attitudes, and experiences of VA cardiac patients: scale development and applicationNancy R Kressin
Center for Health Quality, Outcomes and Economic Research a VA Health Services Research and Development National Center of Excellence, Bedford VA Medical Center, Massachusetts 01730, USA
Med Care 40:I72-85. 2002....
Racial differences in cardiac catheterization as a function of patients' beliefsNancy R Kressin
Center for Health Quality, Outcomes and Economic Research, Bedford Veterans Affairs Medical Center, Bedford, MA 01730, USA
Am J Public Health 94:2091-7. 2004..We examined racial differences in cardiac catheterization rates and reviewed whether patients' beliefs or other variables were associated with observed disparities...
Improving the response choices on the veterans SF-36 health survey role functioning scales: results from the Veterans Health StudyLewis E Kazis
Center for Health Quality, Outcomes and Economic Research, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, MA 01730, USA
J Ambul Care Manage 27:263-80. 2004..Additional work needs to test these improvements in other populations and to expand the analysis to track the responsiveness of the modified scales to clinically and socially important changes over time...
Patient-reported measures of health: The Veterans Health StudyLewis E Kazis
Center for Health Quality Outcomes, and Economic Research CHQOER, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, Mass 01730, USA
J Ambul Care Manage 27:70-83. 2004....
Long-term treatment related complications of brachytherapy for early prostate cancer: a survey of patients previously treatedJ A Talcott
Massachusetts General Hospital, Harvard Medical School and Boston University School of Public Health, Boston, Massachusetts, USA
J Urol 166:494-9. 2001..The morbidity of patients receiving more recent brachytherapy may be less...
Communication about prostate cancer between men and their wivesU Boehmer
School of Public Health, Boston University, and the Center for Health Quality, Outcomes and Economic Research, Bedford, Mass, USA
J Fam Pract 50:226-31. 2001..We explored the perceptions of men who have been treated for metastatic prostate cancer and the views of their wives regarding the changes that were caused by prostate cancer and its treatment...
Quality of life in prostate cancerJames A Talcott
Massachusetts General Hospital, Center for Outcomes Research, Massachusetts General Cancer Centre, 75 Blossom St, Suite 230, Boston, MA 02114 2696, USA
Eur J Cancer 41:922-31. 2005....
Organ conservation in invasive bladder cancer by transurethral resection, chemotherapy and radiation: results of a urodynamic and quality of life study on long-term survivorsAnthony L Zietman
Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, 100 Blossom Street, Cox 302, Boston, MA 02114, USA
J Urol 170:1772-6. 2003..Concern exists about the function of the retained bladder after such therapy...
Comparing the health status of VA and non-VA ambulatory patients: the veterans' health and medical outcomes studiesWilliam H Rogers
Department of Clinical Care Research, New England Medical Center, 750 Washington St, Box 345, Boston, MA 02111, USA
J Ambul Care Manage 27:249-62. 2004..Current economic condition and service-connected disability explain most, if not all, of the differences. The differences were clinically and socially meaningful and would be consistent with substantially higher expected healthcare use...
Individualizing quality-of-life outcomes reporting: how localized prostate cancer treatments affect patients with different levels of baseline urinary, bowel, and sexual functionRonald C Chen
Center for Outcomes Research, Massachusetts General Hospital Cancer Center, Massachusetts General Hospital, Boston, MA, USA
J Clin Oncol 27:3916-22. 2009..Using levels of treatment-related dysfunction, we address these problems and present the final QOL outcomes of our prospective cohort study of patients with early prostate cancer...
Assessing a prostate cancer brachytherapy technique using early patient-reported symptoms: a potential early indicator for technology assessment?Pearl H Seo
Massachusetts General Hospital, Boston, MA 02114 2693, USA
Clin Prostate Cancer 3:38-42. 2004..However, these results suggest that measuring early symptoms may indicate whether an altered brachytherapy treatment technique has intended favorable consequences, potentially accelerating technology assessment...
Patient-reported long-term outcomes after conventional and high-dose combined proton and photon radiation for early prostate cancerJames A Talcott
Center for Outcomes Research, MGH Cancer Center, Massachusetts General Hospital, Boston, Massachusetts, USA
JAMA 303:1046-53. 2010..Increased radiation doses improve prostate cancer control but also increase toxicity to adjacent normal tissue. Proton radiation may attenuate adverse effects...
National Cancer Institute Patient Navigation Research Program: methods, protocol, and measuresKaren M Freund
Women s Health Unit, Department of Medicine, and Women s Health Interdisciplinary Research Center, Boston University School of Medicine, Boston, MA 02118, USA
Cancer 113:3391-9. 2008..To overcome these limitations, a 9-site National Cancer Institute Patient Navigation Research Program (PNRP) was initiated...
Data pooling and analysis to build a preliminary item bank: an example using bowel function in prostate cancerDavid T Eton
Northwestern University School of Medicine, Evanston, IL 60201, USA
Eval Health Prof 28:142-59. 2005..A fifth item assessing hemorrhoids was poorly correlated with other items. Our analyses supported four related components of BF: diarrhea, rectal urgency, pain, and bother/distress...
Preliminary validation of a patient-based self-assessment measure of severity of illness in type 2 diabetes: results from the pilot phase of the Veterans Health StudyMark Linzer
Department of Medicine, University of Wisconsin School of Medicine, Madison, WI 53705, USA
J Ambul Care Manage 28:167-76. 2005..After further testing, this case-mix measure may be suitable for controlling for severity of illness in ambulatory-based studies of diabetic patients with multiple chronic illnesses...
Perceived family history risk and symptomatic diagnosis of prostate cancer: the North Carolina Prostate Cancer Outcomes studyPamela Spain
Cecil G Sheps Center for Health Services Research, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27709 2194, USA
Cancer 113:2180-7. 2008..African American (AA) men remain at significantly greater risk of PrCA diagnosis and mortality than other men. Many factors contribute to the experienced disparities...
The value of the marginalia as an adjunct to structured questionnaires: experiences of men after prostate cancer surgeryLorrie L Powel
University of Central Florida, College of Health and Public Affairs, School of Nursing, Orlando, FL 32816 2210, USA
Qual Life Res 14:827-35. 2005..Future research on outcomes of treatment and clinical inquiry must focus on methods that systematically capture patients' experiences...
Racial differences in how patients perceive physician communication regarding cardiac testingTracie C Collins
Houston Center for Quality of Care and Utilization Studies, Houston VA Medical Center, Texas, USA
Med Care 40:I27-34. 2002..Mistrust may be a source of some of the documented racial variation in health care utilization...
Bringing prostate cancer quality of life research back to the bedside: translating numbers into a format that patients can understandJames A Talcott
Center for Outcomes Research, Massachusetts General Hospital Cancer Center, Massachusetts General Hospital, Boston 02114 2696, USA
J Urol 176:1558-63; discussion 1563-4. 2006..We present an approach that preserves the methodological strengths of validated multi-item measures but provides more accessible information for clinical use...
Utilization of medical services by Veterans Health Study (VHS) respondentsSusan M C Payne
Edmund S Muskie School of Public Service, University of Southern Maine, Portland, ME 04104, USA
J Ambul Care Manage 28:125-40. 2005....
