DOMENIC ANTHONY CIRAULO

Summary

Affiliation: Boston University
Country: USA

Publications

  1. ncbi request reprint Early treatment response in alcohol dependence with extended-release naltrexone
    Domenic A Ciraulo
    Division of Psychiatry, Boston University School of Medicine, Boston, MA 02118 2393, USA
    J Clin Psychiatry 69:190-5. 2008
  2. ncbi request reprint Nefazodone treatment of cocaine dependence with comorbid depressive symptoms
    Domenic A Ciraulo
    Division of Psychiatry, Boston University School of Medicine, VA Boston Healthcare System Medication Development Research Unit MDRU, Boston, MA, USA
    Addiction 100:23-31. 2005
  3. ncbi request reprint Outcome predictors in substance use disorders
    Domenic A Ciraulo
    Division of Psychiatry, Boston University School of Medicine, Doctor s Office Building, 720 Harrison Avenue, Suite 914, Boston, MA 02118, USA
    Psychiatr Clin North Am 26:381-409. 2003
  4. ncbi request reprint Efficacy screening trials of paroxetine, pentoxifylline, riluzole, pramipexole and venlafaxine in cocaine dependence
    Domenic A Ciraulo
    Division of Psychiatry, Boston University School of Medicine, VA Boston Healthcare System Medication Development Research Unit MDRU, Boston, MA, USA
    Addiction 100:12-22. 2005
  5. ncbi request reprint Videotaped cue for urge to drink alcohol
    Chris C Streeter
    Veterans Affairs Boston Healthcare System, Psychiatry Service, Boston, Massachusetts, USA
    Alcohol Clin Exp Res 26:627-34. 2002
  6. pmc Effects of yoga versus walking on mood, anxiety, and brain GABA levels: a randomized controlled MRS study
    Chris C Streeter
    Division of Psychiatry, Boston University School of Medicine, 85 East Newton Street, Boston, MA 02118, USA
    J Altern Complement Med 16:1145-52. 2010
  7. pmc Zonisamide decreases ethanol intake in rats and mice
    Clifford M Knapp
    Division of Psychiatry, Boston University School of Medicine, Boson, MA 02118, USA
    Pharmacol Biochem Behav 87:65-72. 2007
  8. ncbi request reprint Yoga Asana sessions increase brain GABA levels: a pilot study
    Chris C Streeter
    Division of Psychiatry, Boston University School of Medicine, Boston, MA 02118, USA
    J Altern Complement Med 13:419-26. 2007
  9. ncbi request reprint Performance on the Stroop predicts treatment compliance in cocaine-dependent individuals
    Chris C Streeter
    Division of Psychiatry, Boston University School of Medicine, Boston, MA 02118, USA
    Neuropsychopharmacology 33:827-36. 2008
  10. pmc Deep brain stimulation of the nucleus accumbens reduces ethanol consumption in rats
    Clifford M Knapp
    Division of Psychiatry, Boston University School of Medicine, 72 East Concord Street, R 620, Boston, MA 02118, USA
    Pharmacol Biochem Behav 92:474-9. 2009

Detail Information

Publications31

  1. ncbi request reprint Early treatment response in alcohol dependence with extended-release naltrexone
    Domenic A Ciraulo
    Division of Psychiatry, Boston University School of Medicine, Boston, MA 02118 2393, USA
    J Clin Psychiatry 69:190-5. 2008
    ..We sought to determine the time course for onset of effect of intramuscular injectable extended-release naltrexone (XR-NTX), which has demonstrated efficacy for alcohol dependence...
  2. ncbi request reprint Nefazodone treatment of cocaine dependence with comorbid depressive symptoms
    Domenic A Ciraulo
    Division of Psychiatry, Boston University School of Medicine, VA Boston Healthcare System Medication Development Research Unit MDRU, Boston, MA, USA
    Addiction 100:23-31. 2005
    ....
  3. ncbi request reprint Outcome predictors in substance use disorders
    Domenic A Ciraulo
    Division of Psychiatry, Boston University School of Medicine, Doctor s Office Building, 720 Harrison Avenue, Suite 914, Boston, MA 02118, USA
    Psychiatr Clin North Am 26:381-409. 2003
    ..As the ability to subtype disorders based on meaningful biologic differences grows, it is anticipated that several relevant outcome predictors that are specific for pharmacotherapy will emerge...
  4. ncbi request reprint Efficacy screening trials of paroxetine, pentoxifylline, riluzole, pramipexole and venlafaxine in cocaine dependence
    Domenic A Ciraulo
    Division of Psychiatry, Boston University School of Medicine, VA Boston Healthcare System Medication Development Research Unit MDRU, Boston, MA, USA
    Addiction 100:12-22. 2005
    ..The two studies presented here were conducted to assess the efficacy of paroxetine, pentoxifylline, riluzole, venlafaxine and pramipexole as medications for the treatment of cocaine dependence...
  5. ncbi request reprint Videotaped cue for urge to drink alcohol
    Chris C Streeter
    Veterans Affairs Boston Healthcare System, Psychiatry Service, Boston, Massachusetts, USA
    Alcohol Clin Exp Res 26:627-34. 2002
    ..The following hypotheses were tested: (1) individualized cue videotapes can reliably elicit the urge to drink alcohol in alcohol-dependent participants and (2) alcohol drinking histories can predict reactivity to cue...
  6. pmc Effects of yoga versus walking on mood, anxiety, and brain GABA levels: a randomized controlled MRS study
    Chris C Streeter
    Division of Psychiatry, Boston University School of Medicine, 85 East Newton Street, Boston, MA 02118, USA
    J Altern Complement Med 16:1145-52. 2010
    ..The practice of yoga postures is associated with increased brain GABA levels. This study addresses the question of whether changes in mood, anxiety, and GABA levels are specific to yoga or related to physical activity...
  7. pmc Zonisamide decreases ethanol intake in rats and mice
    Clifford M Knapp
    Division of Psychiatry, Boston University School of Medicine, Boson, MA 02118, USA
    Pharmacol Biochem Behav 87:65-72. 2007
    ..These results provide evidence that zonisamide administration will decrease ethanol consumption by both mice and rats in limited access models of drinking, and might, like topiramate, be useful as a medication for alcoholism...
  8. ncbi request reprint Yoga Asana sessions increase brain GABA levels: a pilot study
    Chris C Streeter
    Division of Psychiatry, Boston University School of Medicine, Boston, MA 02118, USA
    J Altern Complement Med 13:419-26. 2007
    ..It was hypothesized that an individual yoga session would be associated with an increase in brain GABA levels...
  9. ncbi request reprint Performance on the Stroop predicts treatment compliance in cocaine-dependent individuals
    Chris C Streeter
    Division of Psychiatry, Boston University School of Medicine, Boston, MA 02118, USA
    Neuropsychopharmacology 33:827-36. 2008
    ..The Stroop task is a widely available, reliable, and valid instrument that can be easily employed to identify and tailor interventions of at risk individuals in the hope of improving treatment compliance...
  10. pmc Deep brain stimulation of the nucleus accumbens reduces ethanol consumption in rats
    Clifford M Knapp
    Division of Psychiatry, Boston University School of Medicine, 72 East Concord Street, R 620, Boston, MA 02118, USA
    Pharmacol Biochem Behav 92:474-9. 2009
    ..These results provide evidence that DBS delivered either to the nucleus accumbens core or shell subregions can significantly reduce ethanol intake in the rat...
  11. doi request reprint The anticonvulsant zonisamide reduces ethanol self-administration by risky drinkers
    Ofra Sarid-Segal
    Boston University School of Medicine, Massachusetts, USA
    Am J Drug Alcohol Abuse 35:316-9. 2009
    ..The purpose of this study is to examine the effects of zonisamide on ethanol self-administration and subjective effects in risky drinkers using a human laboratory paradigm...
  12. ncbi request reprint Prefrontal GABA levels in cocaine-dependent subjects increase with pramipexole and venlafaxine treatment
    Chris C Streeter
    Division of Psychiatry, Boston University School of Medicine, and Boston VA Healthcare System, Boston, MA, USA
    Psychopharmacology (Berl) 182:516-26. 2005
    ..There is evidence that prefrontal lobe GABA levels are low in cocaine-dependent (CD) individuals, and treatment with GABA agonists decreases cocaine self-administration...
  13. pmc Deep brain stimulation of the nucleus accumbens shell attenuates cocaine priming-induced reinstatement of drug seeking in rats
    Fair M Vassoler
    Department of Pharmacology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    J Neurosci 28:8735-9. 2008
    ..Together, these results suggest that DBS of the nucleus accumbens shell may be a potential therapeutic option in the treatment of severe cocaine addiction...
  14. doi request reprint Open label trial of the tolerability and efficacy of zonisamide in the treatment of alcohol dependence
    Clifford M Knapp
    Division of Psychiatry, Boston University School of Medicine, Boston, Massachusetts, USA
    Am J Drug Alcohol Abuse 36:102-5. 2010
    ..The objectives of this study are to assess the tolerability and efficacy of the anticonvulsant zonisamide in an open label trial of the treatment of alcohol dependence...
  15. ncbi request reprint Quetiapine for treatment of alcohol dependence
    Edward P Monnelly
    Division of Psychiatry, Boston University School of Medicine, Boston, MA 02118, USA
    J Clin Psychopharmacol 24:532-5. 2004
    ....
  16. ncbi request reprint Low-dose risperidone as adjunctive therapy for irritable aggression in posttraumatic stress disorder
    Edward P Monnelly
    Division of Psychiatry, Boston University School of Medicine, Boston Massachusetts 02118, USA
    J Clin Psychopharmacol 23:193-6. 2003
    ..These results suggest that low-dose risperidone administration reduces irritability and intrusive thoughts in combat-related PTSD...
  17. ncbi request reprint Clinicians on the front line: active management of depression and anxiety in primary care
    Larry Culpepper
    Department of Family Medicine, Boston University School of Medicine, MA, USA
    JAAPA . 2006
    ..these patients in practice? What are the barriers to diagnosis and treatment, and how can they overcome? What are the treatment options of these sometimes life-altering conditions, and how do we choose from among the many that exist?..
  18. ncbi request reprint Pharmacokinetics and pharmacodynamics of multiple sublingual buprenorphine tablets in dose-escalation trials
    Domenic A Ciraulo
    Division of Psychiatry, Boston Unversity School of Medicine, Massachusetts 02118, USA
    J Clin Pharmacol 46:179-92. 2006
    ..They also indicate a lack of dose proportionality for buprenorphine sublingual tablets, at least during the times at which levels of this agent are highest...
  19. ncbi request reprint Dose-ranging kinetics and behavioral pharmacology of naltrexone and acamprosate, both alone and combined, in alcohol-dependent subjects
    Bankole A Johnson
    Department of Psychiatry, The University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, Mail Stop 7792, San Antonio, TX 78229 3900, USA
    J Clin Psychopharmacol 23:281-93. 2003
    ..More side effects were noted with the combination of medications than with either medication alone. Naltrexone administration significantly increased plasma acamprosate levels...
  20. pmc Cost and cost-effectiveness of the COMBINE study in alcohol-dependent patients
    Gary A Zarkin
    RTI International, 3040 Cornwallis Rd, Research Triangle Park, NC 27709, USA
    Arch Gen Psychiatry 65:1214-21. 2008
    ..The costs and cost-effectiveness of these combinations are unknown and of interest to clinicians and policy makers...
  21. doi request reprint Improvement of physical health and quality of life of alcohol-dependent individuals with topiramate treatment: US multisite randomized controlled trial
    Bankole A Johnson
    Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, VA 22908 0623, USA
    Arch Intern Med 168:1188-99. 2008
    ..We sought to determine whether topiramate's antidrinking effects are bolstered by improvements in physical and psychosocial well-being...
  22. ncbi request reprint Topiramate for treating alcohol dependence: a randomized controlled trial
    Bankole A Johnson
    Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, VA 22908, USA
    JAMA 298:1641-51. 2007
    ....
  23. ncbi request reprint A double-blind, placebo-controlled trial of tiagabine for the treatment of cocaine dependence
    Theresa Winhusen
    Department of Psychiatry, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267, USA
    Drug Alcohol Depend 91:141-8. 2007
    ..The potential efficacy of tiagabine for treating cocaine dependence is suggested by both pre-clinical research and two small clinical trials...
  24. ncbi request reprint A double-blind, placebo-controlled trial of reserpine for the treatment of cocaine dependence
    Theresa Winhusen
    Department of Psychiatry, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267, USA
    Drug Alcohol Depend 91:205-12. 2007
    ..The potential efficacy of reserpine, a dopamine depletor, for treating cocaine dependence is suggested by both pre-clinical research and a small clinical trial...
  25. ncbi request reprint Frontal lobe GABA levels in cocaine dependence: a two-dimensional, J-resolved magnetic resonance spectroscopy study
    Yong Ke
    Brain Imaging Center, McLean Hospital, 115 Mill St, Belmont, MA 02478, USA
    Psychiatry Res 130:283-93. 2004
    ..However, cocaine-dependent subjects without an alcohol disorder (N=12) also had lower GABA levels (1.04 mM/kg) than the comparison subjects (t [d.f.=30]=2.09, P=0.045), suggesting that cocaine dependence alone can decrease GABA levels...
  26. ncbi request reprint Combined pharmacotherapies and behavioral interventions for alcohol dependence: the COMBINE study: a randomized controlled trial
    Raymond F Anton
    Center for Drug and Alcohol Programs, Medical University of South Carolina, Charleston 29425, USA
    JAMA 295:2003-17. 2006
    ..Alcohol dependence treatment may include medications, behavioral therapies, or both. It is unknown how combining these treatments may impact their effectiveness, especially in the context of primary care and other nonspecialty settings...
  27. ncbi request reprint An open-label pilot study of methylphenidate in the treatment of cocaine dependent patients with adult attention deficit/hyperactivity disorder
    Eugene C Somoza
    Cincinnati VA UC NIDA MDRU, VA Medical Center, 3200 Vine Street, Cincinnati, OH 45220, USA
    J Addict Dis 23:77-92. 2004
    ..Quantitative benzoylecgonine indicated that only those participants categorized as being compliant showed improvement. A double-blind, placebo-controlled study of methylphenidate for this population may be warranted...
  28. ncbi request reprint White matter hyperintensities in subjects with cocaine and opiate dependence and healthy comparison subjects
    In Kyoon Lyoo
    McLean Hospital Brain Imaging Center and Department of Psychiatry, Harvard Medical School, 115 Mill Street, Belmont, MA 02478, USA
    Psychiatry Res 131:135-45. 2004
    ..Also, there was a trend for lower WMH severity in substance-dependent women relative to the healthy comparison group, possibly due to estrogen's protective effect against cerebrovascular accidents...
  29. ncbi request reprint Cerebellar gray matter volume correlates with duration of cocaine use in cocaine-dependent subjects
    Minyoung E Sim
    Department of Psychiatry, Seoul National University College of Medicine, Seoul 110 744, South Korea
    Neuropsychopharmacology 32:2229-37. 2007
    ....
  30. ncbi request reprint Safety and efficacy of GABAergic medications for treating alcoholism
    Bankole A Johnson
    Department of Psychiatric Medicine, The University of Virginia, Charlottesville, Virginia 22908 0623, USA
    Alcohol Clin Exp Res 29:248-54. 2005
    ..Johnson; (5) Evaluating the Risk of Benzodiazepine Prescription to Alcohol-Dependent Individuals, by Domenic A. Ciraulo; and (6) Safety and Efficacy of GABAergic Agents in Treating Alcoholics: Discussion, by Robert M. Swift...
  31. ncbi request reprint Cocaine Rapid Efficacy Screening Trials (CREST): lessons learned
    Kyle M Kampman
    Philadelphia Veterans Affairs Medical Center, Philadelphia, PA, USA
    Addiction 100:102-10. 2005
    ....

Research Grants9

  1. Interdisciplinary Study of Two Novel Anticonvulants in Alcoholism
    DOMENIC ANTHONY CIRAULO; Fiscal Year: 2010
    ..The goal of the current study is to find more effective and safer medications for alcoholism by studying agents that differ in chemical structure and pharmacologic actions from those currently available. ..
  2. BOSTON UNIVERSITY CRU FOR ALCOHOLISM TREATMENT
    Domenic Ciraulo; Fiscal Year: 2004
    ..However, each study site has provided site-specific information on the budget, budget justifications, listing of key personnel, consultant/consortium agreements, and human subjects sections of their respective proposals. ..
  3. Cognitive-Behavioral Therapy & Venlafaxine Treatments For Anxiety In Alcoholism
    Domenic Ciraulo; Fiscal Year: 2007
    ..abstract_text> ..
  4. Interdisciplinary Study of Two Novel Anticonvulants in Alcoholism
    Domenic Ciraulo; Fiscal Year: 2009
    ..The goal of the current study is to find more effective and safer medications for alcoholism by studying agents that differ in chemical structure and pharmacologic actions from those currently available. ..