Research Topics
| Hyon ChoiSummaryAffiliation: Boston University Country: USA Publications
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Detail Information
Publications
Vitamin C intake and the risk of gout in men: a prospective studyHyon K Choi
Division of Rheumatology, Department of Medicine, Arthritis Research Centre of Canada, Vancouver General Hospital, University of British Columbia, Vancouver, Canada
Arch Intern Med 169:502-7. 2009..Several metabolic studies and a recent double-blind, placebo-controlled, randomized trial have shown that higher vitamin C intake significantly reduces serum uric acid levels. Yet the relation with risk of gout is unknown...
Risk factors for pseudogout in the general populationYoung Hee Rho
Section of Rheumatology and the Clinical Epidemiology Unit, Boston University School of Medicine, 650 Albany Street, Suite 200, Boston, MA 02118, USA
Rheumatology (Oxford) 51:2070-4. 2012..Avoiding loop diuretics may help individuals with recurrent pseudogout...
The independent association between parathyroid hormone levels and hyperuricemia: a national population studyJanet Y Hui
The Clinical Epidemiology Unit, Boston University School of Medicine, 650 Albany Street, Suite 200, Boston, MA 02118, USA
Arthritis Res Ther 14:R56. 2012..We evaluated the potential population impact of PTH on serum uric acid (SUA) levels by using a nationally representative sample of United States adults...
Dual energy CT in gout: a prospective validation studyHyon K Choi
Section of the Rheumatology and the Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA 02118, USA
Ann Rheum Dis 71:1466-71. 2012..The authors prospectively determined: (1) the specificity and sensitivity of dual energy CT (DECT) for gout; and (2) the interobserver and intraobserver reproducibility for DECT urate volume measurements...
Obesity and the risk of psoriatic arthritis: a population-based studyThorvardur Jon Love
Department of Science, Education, and Innovation, Landspitali University Hospital, Fossvogur, Reykjavik, Iceland
Ann Rheum Dis 71:1273-7. 2012..Obesity is associated with an increased risk of psoriasis; however, its potential impact on the risk of psoriatic arthritis (PsA) remains unclear...
Antihypertensive drugs and risk of incident gout among patients with hypertension: population based case-control studyHyon K Choi
Section of Rheumatology and the Clinical Epidemiology Unit, Boston University School of Medicine, 650 Albany Street, Boston, MA 02118, USA
BMJ 344:d8190. 2012..To determine the independent associations of antihypertensive drugs with the risk of incident gout among people with hypertension...
Fructose-rich beverages and risk of gout in womenHyon K Choi
Section of Rheumatology and Clinical Epidemiology Unit, Boston University School of Medicine, 650 Albany St, Ste 200, Boston, MA 02118, USA
JAMA 304:2270-8. 2010..Fructose-rich beverages such as sugar-sweetened soda and orange juice can increase serum uric acid levels and, thus, the risk of gout, but prospective data on the relationship are limited...
A prescription for lifestyle change in patients with hyperuricemia and goutHyon K Choi
Section of Rheumatology and the Clinical Epidemiology Unit, Boston, Massachusetts 02118, USA
Curr Opin Rheumatol 22:165-72. 2010....
Genetics of goutHyon K Choi
Section of Rheumatology and the Clinical Epidemiology Unit, Boston University School of Medicine, Boston, Massachusetts 02118, USA
Curr Opin Rheumatol 22:144-51. 2010..This review provides an update on recent findings with regards to the genetics of hyperuricemia and gout, including recent data from genome-wide association studies (GWAS)...
Coffee consumption and risk of incident gout in women: the Nurses' Health StudyHyon K Choi
Section of Rheumatology and the Clinical Epidemiology Unit, School of Medicine, Boston University, Boston, MA 02118, USA
Am J Clin Nutr 92:922-7. 2010..Coffee is one of the most widely consumed beverages in the world and may affect the risk of gout via various mechanisms, but prospective data on the relation between coffee intake and the risk of incident gout are limited...
Serum uric acid levels and the risk of type 2 diabetes: a prospective studyVidula Bhole
Arthritis Research Centre of Canada, Vancouver, BC, Canada
Am J Med 123:957-61. 2010..To evaluate the impact of serum uric acid levels on the future risk of developing type 2 diabetes independent of other factors...
Epidemiology of gout in women: Fifty-two-year followup of a prospective cohortVidula Bhole
Boston University School of Medicine, Boston, Massachusetts 02118, USA
Arthritis Rheum 62:1069-76. 2010..We undertook this study to evaluate purported risk factors for incident gout among women and to compare them with those among men...
Fructose and vitamin C intake do not influence risk for developing hypertensionJohn P Forman
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, 3rd Floor, 181 Longwood Avenue, Boston, Massachusetts 02115, USA
J Am Soc Nephrol 20:863-71. 2009..02 (0.91 to 1.14) in Nurses' Health Study 2, and 1.06 (0.97 to 1.15) in Health Professionals Follow-up Study. In conclusion, fructose and vitamin C intake do not substantially influence the risk for developing hypertension...
Gout and the risk of Parkinson's disease: a cohort studyMary De Vera
Arthritis Research Centre of Canada and University of British Columbia, Vancouver, British Columbia, Canada
Arthritis Rheum 59:1549-54. 2008..Our objective was to examine the relationship between gout and the risk of PD in persons age > or = 65 years...
Impact of statin discontinuation on mortality in patients with rheumatoid arthritis: a population-based studyMary A De Vera
Arthritis Research Centre of Canada, Vancouver, British Columbia, Canada
Arthritis Care Res (Hoboken) 64:809-16. 2012..To evaluate the impact of statin discontinuation on cardiovascular disease (CVD) mortality and all-cause mortality in a population-based cohort of patients with rheumatoid arthritis (RA)...
Uric acid and insulin sensitivity and risk of incident hypertensionJohn P Forman
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
Arch Intern Med 169:155-62. 2009..Corresponding circulating biomarkers are associated with risk of hypertension, but because these factors may be interrelated, whether they independently affect risk is unknown...
Menopause, postmenopausal hormone use and risk of incident goutA Elisabeth Hak
Section of Rheumatology and the Clinical Epidemiology Unit, Boston University of School of Medicine, 650 Albany Street, Suite 200, Boston, MA 02118, USA
Ann Rheum Dis 69:1305-9. 2010..To prospectively study the relation between menopause, postmenopausal hormone use and risk of gout, since female sex hormones have been postulated to decrease gout risk among women...
Vitamin C intake and serum uric acid concentration in menXiang Gao
Department of Nutrition, Harvard University School of Public Health, Boston, Massachusetts 02115, USA
J Rheumatol 35:1853-8. 2008..We examined associations between vitamin C intake and serum uric acid in men in a population-based study...
Pathogenesis of goutHyon K Choi
Arthritis Research Centre of Canada, University of British Columbia, Vancouver, British Columbia, Canada
Ann Intern Med 143:499-516. 2005
Evaluation and treatment of vasculitis in the critically ill patientPeter A Merkel
Rheumatology Section, Boston Medical Center, Arthritis Center, Boston University School of Medicine, 730 Albany Street, Boston, MA 02118, USA
Crit Care Clin 18:321-44. 2002..Rapid initiation of immunosuppressive therapy for critically ill patients with vasculitis is crucial and may be life-saving...
Obesity, weight change, hypertension, diuretic use, and risk of gout in men: the health professionals follow-up studyHyon K Choi
Rheumatology Unit, Department of Medicine, Massachusetts General Hospital, MA 02114, USA
Arch Intern Med 165:742-8. 2005..Similarly, both hypertension and diuretic use have been considered risk factors for gout; however, their independent contributions have not been established prospectively...
Soft drinks, fructose consumption, and the risk of gout in men: prospective cohort studyHyon K Choi
Arthritis Research Centre of Canada, Department of Medicine, Vancouver General Hospital, University of British Columbia, Vancouver, BC V5Z 1L7, Canada
BMJ 336:309-12. 2008..To examine the relation between intake of sugar sweetened soft drinks and fructose and the risk of incident gout in men...
Purine-rich foods, dairy and protein intake, and the risk of gout in menHyon K Choi
Rheumatology Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA
N Engl J Med 350:1093-103. 2004..Similarly, the possibility that the consumption of dairy products has a role in protecting against gout has been raised by metabolic studies. We prospectively investigated the association of these dietary factors with new cases of gout...
Purine-rich foods intake and recurrent gout attacksYuqing Zhang
Boston University, Boston University School of Medicine, 715 Albany Street, A203, Boston, Massachusetts, MA 02118, USA
Ann Rheum Dis 71:1448-53. 2012..To examine and quantify the relation between purine intake and the risk of recurrent gout attacks among gout patients...
Intake of added sugar and sugar-sweetened drink and serum uric acid concentration in US men and womenXiang Gao
Department of Nutrition, Harvard University School of Public Health, Boston, MA 02115, USA
Hypertension 50:306-12. 2007..2; P for interaction <0.01). Further research is needed to confirm causality of these associations and the observed difference by gender...
Psoriasis and the risk of diabetes and hypertension: a prospective study of US female nursesAbrar A Qureshi
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, 45 Francis St, 221L, Boston, MA 02115, USA
Arch Dermatol 145:379-82. 2009..To evaluate the independent association between psoriasis and risk of diabetes and hypertension...
Diet, alcohol, and gout: how do we advise patients given recent developments?Hyon K Choi
Rheumatology Unit, Bulfinch 165, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
Curr Rheumatol Rep 7:220-6. 2005..These recommendations should reinforce established recommendations where the influence on gout parallels the influence on other diseases, and consider modifying the recommendations where they are divergent...
Prevalence of the metabolic syndrome in individuals with hyperuricemiaHyon K Choi
Rheumatology Division, Arthritis Research Centre of Canada, Department of Medicine, Vancouver General Hospital, University of British Columbia, Vancouver, Canada
Am J Med 120:442-7. 2007..Our objective was to determine the prevalence of the metabolic syndrome according to serum uric acid levels in a nationally representative sample of US adults...
Serial ANCA titers: useful tool for prevention of relapses in ANCA-associated vasculitisWon K Han
Massachusetts General Hospital and Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA
Kidney Int 63:1079-85. 2003..Moreover, adjustment of immunosuppression based on lesser titer changes appears to result in a favorable outcome...
Opportunistic infections are preceded by a rapid fall in antineutrophil cytoplasmic antibody (ANCA) titer in patients with ANCA associated vasculitisRunolfur Palsson
Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston 02114, USA
J Rheumatol 29:505-10. 2002..Therefore, changes in ANCA titer can help distinguish opportunistic infections from vasculitis flares when patients with AAV present with indeterminate clinical findings...
Sugar-sweetened soft drinks, diet soft drinks, and serum uric acid level: the Third National Health and Nutrition Examination SurveyJee Woong J Choi
Arthritis Research Centre of Canada, Vancouver, British Columbia, Canada
Arthritis Rheum 59:109-16. 2008..Our objective was to evaluate the relationship between sugar-sweetened soft drink intake, diet soft drink intake, and serum uric acid levels in a nationally representative sample of men and women...
Coffee, tea, and caffeine consumption and serum uric acid level: the third national health and nutrition examination surveyHyon K Choi
Arthritis Research Centre of Canada, Vancouver General Hospital, University of British Columbia, Vancouver, Canada
Arthritis Rheum 57:816-21. 2007..Our objective was to evaluate the relationship between coffee, tea, and caffeine intake and serum uric acid level in a nationally representative sample of men and women...
Dairy consumption and risk of type 2 diabetes mellitus in men: a prospective studyHyon K Choi
Department of Medicine, Massachusetts General Hospital, Boston, Mass 02114, USA
Arch Intern Med 165:997-1003. 2005..While a strong inverse association has been reported between dairy consumption and the insulin resistance syndrome among young obese adults, the relation between dairy intake and type 2 diabetes is unknown...
A Pilot Study Identifying Statin Nonadherence With Visit-to-Visit Variability of Low-Density Lipoprotein CholesterolDevin M Mann
Department of Medicine, Boston University School of Medicine, Boston, Massachusetts Electronic address
Am J Cardiol 111:1437-42. 2013..Furthermore, a VVV of LDL cholesterol-based model had good discrimination characteristics for statin nonadherence. Research is needed to validate and generalize these findings to other populations and biomarkers...
Statin discontinuation and risk of acute myocardial infarction in patients with rheumatoid arthritis: a population-based cohort studyMary A De Vera
University of British Columbia School of Population and Public Health, Arthritis Research Centre of Canada, 895 W 10th Avenue, Vancouver, BC, Canada V5Z 1L7
Ann Rheum Dis 70:1020-4. 2011..However, poor compliance with statins may limit their therapeutic benefit. Our objective was to evaluate the impact of statin discontinuation on risk of acute myocardial infarction (AMI) among RA patients...
Plasma uric acid level and risk for incident hypertension among menJohn P Forman
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
J Am Soc Nephrol 18:287-92. 2007..24; 95% CI 0.93 to 1.66). In conclusion, no independent association between UA level and risk for incident hypertension was found among older men...
Gout: epidemiology and lifestyle choicesHyon K Choi
Rheumatology Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
Curr Opin Rheumatol 17:341-5. 2005..Recent scientific data serve to illuminate the links between dietary and other factors and the incidence of gout. This review summarizes recent literature about the prevalence and incidence of gout as well as risk factors for gout...
Dietary risk factors for rheumatic diseasesHyon K Choi
Rheumatology Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
Curr Opin Rheumatol 17:141-6. 2005..Recent scientific data illuminate the dietary link to rheumatic disorders. This review summarizes recently published articles on the dietary link to rheumatoid arthritis, gout, and osteoarthritis...
Intake of purine-rich foods, protein, and dairy products and relationship to serum levels of uric acid: the Third National Health and Nutrition Examination SurveyHyon K Choi
Rheumatology Unit, Bulfinch 165, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA
Arthritis Rheum 52:283-9. 2005..Our objective was to evaluate the relationship between dietary factors and serum uric acid levels in a nationally representative sample of men and women in the US...
Diet, urate, and Parkinson's disease risk in menXiang Gao
Department of Nutrition, School of Public Health, Harvard University, Boston, MA 02115, USA
Am J Epidemiol 167:831-8. 2008..These potential benefits, however, should be weighed against expected adverse effects on risk of gout and other chronic diseases...
Prevalence of the metabolic syndrome in patients with gout: the Third National Health and Nutrition Examination SurveyHyon K Choi
Arthritis Research Centre of Canada, Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia, Canada
Arthritis Rheum 57:109-15. 2007..To determine the prevalence of metabolic syndrome among patients with gout and to examine the association between the 2 conditions in a nationally representative sample of US adults...
Independent impact of gout on mortality and risk for coronary heart diseaseHyon K Choi
Rheumatology Division, Arthritis Research Centre of Canada, Department of Medicine, Vancouver General Hospital, University of British Columbia, Vancouver, Canada
Circulation 116:894-900. 2007..Furthermore, although many studies have suggested that hyperuricemia is associated with cardiovascular disease (CVD), limited data are available on the impact of gout on CVD...
Coffee consumption and risk of incident gout in men: a prospective studyHyon K Choi
Arthritis Research Centre of Canada, Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia, Canada
Arthritis Rheum 56:2049-55. 2007..We prospectively evaluated the relationship between coffee intake and the risk of incident gout in a large cohort of men...
Hyperuricemia and coronary heart disease: a systematic review and meta-analysisSeo Young Kim
Brigham and Women s Hospital, Boston, Massachusetts, USA
Arthritis Care Res (Hoboken) 62:170-80. 2010..The role of serum uric acid as an independent risk factor for cardiovascular disease remains unclear, although hyperuricemia is associated with cardiovascular disease such as coronary heart disease (CHD), stroke, and hypertension...
The risk of hospitalized infection in patients with rheumatoid arthritisAllison L Smitten
Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
J Rheumatol 35:387-93. 2008..To determine whether patients with rheumatoid arthritis (RA) are at increased risk of hospitalized infection and whether the risk varies by RA treatment...
Alcohol intake and risk of incident gout in men: a prospective studyHyon K Choi
Rheumatology Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
Lancet 363:1277-81. 2004..Additionally, potential differences in risk of gout posed by different alcoholic beverages have not been assessed...
Beer, liquor, and wine consumption and serum uric acid level: the Third National Health and Nutrition Examination SurveyHyon K Choi
Massachusetts General Hospital, Harvard Medical School, and Harvard School of Public Health, Boston, Massachusetts 02114, USA
Arthritis Rheum 51:1023-9. 2004..To evaluate the relationship between intakes of beer, liquor, and wine and serum uric acid levels in a nationally representative sample of men and women...
The risk of herpes zoster in patients with rheumatoid arthritis in the United States and the United KingdomAllison L Smitten
Harvard School of Public Health, Boston, Massachusetts 02115, USA
Arthritis Rheum 57:1431-8. 2007..To determine whether the incidence of herpes zoster is elevated in patients with rheumatoid arthritis (RA) and whether herpes zoster is associated with use of disease-modifying antirheumatic drugs (DMARDs) in patients with RA...
Smoking and the risk of psoriasis in women: Nurses' Health Study IIArathi R Setty
Department of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass, USA
Am J Med 120:953-9. 2007..Psoriasis is a common, chronic, inflammatory skin disorder. Smoking may increase the risk of psoriasis, but no prospective data are available on this relation...
A prospective study of dairy intake and the risk of type 2 diabetes in womenSimin Liu
Division of Preventive Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
Diabetes Care 29:1579-84. 2006..Although studies have indicated that increased dairy intake may reduce risk of overweight and insulin resistance syndrome, data directly relating dairy intake to type 2 diabetes remain sparse...
Obesity, waist circumference, weight change, and the risk of psoriasis in women: Nurses' Health Study IIArathi R Setty
Department of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, USA
Arch Intern Med 167:1670-5. 2007..Psoriasis is a common, chronic, inflammatory skin disorder. Higher adiposity may increase the risk of psoriasis, but, to our knowledge, no prospective data are available on this relationship...
Glucocorticoid use, other associated factors, and the risk of tuberculosisSusan S Jick
Boston Collaborative Drug Surveillance Program, Boston University School of Medicine, Lexington, MA, USA
Arthritis Rheum 55:19-26. 2006..Low adiposity, diabetes, current smoking, and obstructive pulmonary disorders are also important independent risk factors for tuberculosis...
Independent impact of gout on the risk of acute myocardial infarction among elderly women: a population-based studyMary A De Vera
Arthritis Research Centre of Canada, Vancouver, British Columbia, Canada
Ann Rheum Dis 69:1162-4. 2010..Men with gout have been found to have an increased risk of acute myocardial infarction (AMI), but no corresponding data are available among women...
Research Grants
- Genetics of GoutHyon K Choi; Fiscal Year: 2010....
- Genetics of GoutHyon K Choi; Fiscal Year: 2009....
