ANDREW BUDSON

Summary

Affiliation: Boston University
Country: USA

Publications

  1. doi request reprint New criteria for Alzheimer disease and mild cognitive impairment: implications for the practicing clinician
    Andrew E Budson
    Center for Translational Cognitive Neuroscience, VA Boston Healthcare System, Boston, MA, USA
    Neurologist 18:356-63. 2012
  2. doi request reprint New diagnostic criteria for Alzheimer's disease and mild cognitive impairment for the practical neurologist
    Andrew E Budson
    Center for Translational Cognitive Neuroscience, VA Boston Healthcare System, Boston, MA 02132, USA
    Pract Neurol 12:88-96. 2012
  3. ncbi request reprint Episodic memory in Alzheimer's disease: separating response bias from discrimination
    Andrew E Budson
    Geriatric Research Education Clinical Center, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, MA 01730, USA
    Neuropsychologia 44:2222-32. 2006
  4. ncbi request reprint Electrophysiological dissociation of picture versus word encoding: the distinctiveness heuristic as a retrieval orientation
    Andrew E Budson
    Edith Nourse Rogers Memorial Veterans Hospital, Bedford, MA 01730, and Boston University, Boston, MA, USA
    J Cogn Neurosci 17:1181-93. 2005
  5. ncbi request reprint Memory for the September 11, 2001, terrorist attacks one year later in patients with Alzheimer's disease, patients with mild cognitive impairment, and healthy older adults
    Andrew E Budson
    Geriatric Research Education Clinical Center, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, MA 01730, USA
    Cortex 43:875-88. 2007
  6. doi request reprint Understanding memory dysfunction
    Andrew E Budson
    Center for Translational Cognitive Neuroscience, Bedford VA Hospital, Bedford, MA 01730, USA
    Neurologist 15:71-9. 2009
  7. ncbi request reprint Memory dysfunction in neurological practice
    Andrew E Budson
    Geriatric Research Educational Clinical Center, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, MA 01730, USA
    Pract Neurol 7:42-7. 2007
  8. ncbi request reprint Gist memory in Alzheimer's disease: evidence from categorized pictures
    Andrew E Budson
    Geriatric Research Education Clinical Center, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, MA 01730, USA
    Neuropsychology 20:113-22. 2006
  9. ncbi request reprint Memory for choices in Alzheimer's disease
    Andrew E Budson
    Geriatric Research Education Clinical Center, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, MA 01730, USA
    Dement Geriatr Cogn Disord 22:150-8. 2006
  10. ncbi request reprint False recognition of emotional word lists in aging and Alzheimer disease
    Andrew E Budson
    Geriatric Research Education Clinical Center, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, MA 01730, USA
    Cogn Behav Neurol 19:71-8. 2006

Research Grants

Detail Information

Publications53

  1. doi request reprint New criteria for Alzheimer disease and mild cognitive impairment: implications for the practicing clinician
    Andrew E Budson
    Center for Translational Cognitive Neuroscience, VA Boston Healthcare System, Boston, MA, USA
    Neurologist 18:356-63. 2012
    ..Developments over the last 27 years have lead to the need for new diagnostic criteria...
  2. doi request reprint New diagnostic criteria for Alzheimer's disease and mild cognitive impairment for the practical neurologist
    Andrew E Budson
    Center for Translational Cognitive Neuroscience, VA Boston Healthcare System, Boston, MA 02132, USA
    Pract Neurol 12:88-96. 2012
    ..As new diagnostic tools and treatments for AD become available, diagnoses using these criteria will enable patients with AD dementia, MCI due to AD and eventually preclinical AD to receive the best possible care...
  3. ncbi request reprint Episodic memory in Alzheimer's disease: separating response bias from discrimination
    Andrew E Budson
    Geriatric Research Education Clinical Center, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, MA 01730, USA
    Neuropsychologia 44:2222-32. 2006
    ..Possible explanations of this liberal response bias in patients with AD are discussed...
  4. ncbi request reprint Electrophysiological dissociation of picture versus word encoding: the distinctiveness heuristic as a retrieval orientation
    Andrew E Budson
    Edith Nourse Rogers Memorial Veterans Hospital, Bedford, MA 01730, and Boston University, Boston, MA, USA
    J Cogn Neurosci 17:1181-93. 2005
    ....
  5. ncbi request reprint Memory for the September 11, 2001, terrorist attacks one year later in patients with Alzheimer's disease, patients with mild cognitive impairment, and healthy older adults
    Andrew E Budson
    Geriatric Research Education Clinical Center, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, MA 01730, USA
    Cortex 43:875-88. 2007
    ..Lastly, although memory distortions were common among all groups, they were greatest in the patients with AD...
  6. doi request reprint Understanding memory dysfunction
    Andrew E Budson
    Center for Translational Cognitive Neuroscience, Bedford VA Hospital, Bedford, MA 01730, USA
    Neurologist 15:71-9. 2009
    ..Neurologic injury may cause damage to one or more of these memory systems...
  7. ncbi request reprint Memory dysfunction in neurological practice
    Andrew E Budson
    Geriatric Research Educational Clinical Center, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, MA 01730, USA
    Pract Neurol 7:42-7. 2007
  8. ncbi request reprint Gist memory in Alzheimer's disease: evidence from categorized pictures
    Andrew E Budson
    Geriatric Research Education Clinical Center, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, MA 01730, USA
    Neuropsychology 20:113-22. 2006
    ..Implications of these findings for understanding gist memory and response bias in patients with AD are discussed...
  9. ncbi request reprint Memory for choices in Alzheimer's disease
    Andrew E Budson
    Geriatric Research Education Clinical Center, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, MA 01730, USA
    Dement Geriatr Cogn Disord 22:150-8. 2006
    ..This finding suggests that patients with mild AD are less likely to engage in feature-by-feature comparison processes across choice options, a change that may lead them to make qualitatively different choices than healthy older adults...
  10. ncbi request reprint False recognition of emotional word lists in aging and Alzheimer disease
    Andrew E Budson
    Geriatric Research Education Clinical Center, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, MA 01730, USA
    Cogn Behav Neurol 19:71-8. 2006
    ..To examine 3 different aspects of the emotional memory effect in aging and Alzheimer disease (AD): item-specific recollection, gist memory, and recognition response bias...
  11. ncbi request reprint Age-related differences in novelty and target processing among cognitively high performing adults
    Kirk R Daffner
    Brigham Behavioral Neurology Group, Division of Cognitive and Behavioral Neurology, Department of Neurology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Neurobiol Aging 26:1283-95. 2005
    ....
  12. ncbi request reprint False recognition in Alzheimer disease: evidence from categorized pictures
    Andrew E Budson
    Division of Cognitive and Behavioral Neurology, Department of Neurology, Brigham and Women s Hospital, Boston, MA 02115, USA
    Cogn Behav Neurol 16:16-27. 2003
    ..To better understand memory distortions and false recognition in patients with Alzheimer disease (AD), using a paradigm of categorized color photographs...
  13. ncbi request reprint Patients with mild Alzheimer's disease attribute conceptual fluency to prior experience
    David A Wolk
    Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA
    Neuropsychologia 43:1662-72. 2005
    ..These findings suggest that patients with mild AD are able to use conceptual fluency in their recognition judgments and the neural mechanisms supporting such processing is maintained...
  14. ncbi request reprint Increased responsiveness to novelty is associated with successful cognitive aging
    Kirk R Daffner
    Division of Cognitive and Behavioral Neurology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    J Cogn Neurosci 18:1759-73. 2006
    ....
  15. ncbi request reprint Metacognition and false recognition in patients with frontal lobe lesions: the distinctiveness heuristic
    Andrew E Budson
    Department of Neurology 4 18F, Brigham and Women s Hospital, Boston, MA 02120, USA
    Neuropsychologia 43:860-71. 2005
    ..The authors suggest that the distinctiveness heuristic is a metacognitive strategy, dependent upon the frontal lobes, that may be engaged by healthy individuals to reduce their false recognition...
  16. pmc Preserved metamemorial ability in patients with mild Alzheimer's disease: shifting response bias
    Jill D Waring
    Geriatric Research Education Clinical Center, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, MA, USA
    Brain Cogn 66:32-9. 2008
    ....
  17. pmc Cognitive status impacts age-related changes in attention to novel and target events in normal adults
    Kirk R Daffner
    Brigham Behavioral Neurology Group, Division of Cognitive and Behavioral Neurology, Department of Neurology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Neuropsychology 21:291-300. 2007
    ..Moreover, the results support the notion of there being different patterns of normal cognitive aging and the need to identify the factors that influence them...
  18. ncbi request reprint An electrophysiological investigation of the relationship between conceptual fluency and familiarity
    David A Wolk
    Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA
    Neurosci Lett 369:150-5. 2004
    ..The effects on the N400 may be related to the impact of fluency on familiarity, whereas later processing may be involved in the attribution of fluency to prior experience...
  19. ncbi request reprint The P300 component in patients with Alzheimer's disease and their biological children
    Brandon A Ally
    Harvard Medical School and New England GRECC, Geriatric Neuropsychology Laboratory, USA
    Biol Psychol 72:180-7. 2006
    ..In addition to examining P300 in patients with AD, the current study examined the utility of P300 as a preclinical marker in the offspring of AD patients...
  20. pmc Aging memory for pictures: using high-density event-related potentials to understand the effect of aging on the picture superiority effect
    Brandon A Ally
    Center for Translational Cognitive Neuroscience, Geriatric Research Education Clinical Center, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, MA 01730, United States
    Neuropsychologia 46:679-89. 2008
    ..The findings of this study suggest that pictures allow older adults to compensate for their impaired memorial processes, and may allow these memorial components to function more effectively in older adults...
  21. pmc TDP-43 proteinopathy and motor neuron disease in chronic traumatic encephalopathy
    Ann C McKee
    Geriatric Research Education Clinical Center, Bedford Veterans Administration Hospital, Bedford, Massachusetts 01730, USA
    J Neuropathol Exp Neurol 69:918-29. 2010
    ..This is the first pathological evidence that repetitive head trauma experienced in collision sports might be associated with the development of a motor neuron disease...
  22. pmc Diagnostic retrieval monitoring in patients with frontal lobe lesions: further exploration of the distinctiveness heuristic
    David Y Hwang
    Geriatric Research Education Clinical Center, Edith Nourse Rogers Memorial Veterans Hospital, 200 Springs Road, Bedford, MA 01730, USA
    Neuropsychologia 45:2543-52. 2007
    ..This result suggests that the frontal lobes are necessary for self-initiation of this strategy during recognition memory tasks...
  23. pmc The picture superiority effect in patients with Alzheimer's disease and mild cognitive impairment
    Brandon A Ally
    Geriatric Research Education Clinical Center, Bedford VA Hospital, Bedford, MA, USA
    Neuropsychologia 47:595-8. 2009
    ..The findings are discussed in terms of visual processing and possible clinical importance...
  24. pmc Music as a memory enhancer in patients with Alzheimer's disease
    Nicholas R Simmons-Stern
    Center for Translational Cognitive Neuroscience, Geriatric Research Education Clinical Center, Bedford VA Hospital, Bedford, MA 01730, United States
    Neuropsychologia 48:3164-7. 2010
    ....
  25. pmc Response bias for picture recognition in patients with Alzheimer disease
    Ellen H Beth
    Center for Translational Cognitive Neuroscience, Geriatric Research Education Clinical Center, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, MA
    Cogn Behav Neurol 22:229-35. 2009
    ..To investigate whether changing recognition stimuli from words to pictures would alter response bias in patients with Alzheimer disease (AD)...
  26. pmc Chronic traumatic encephalopathy in athletes: progressive tauopathy after repetitive head injury
    Ann C McKee
    Department of Neurology, Center for the Study of Traumatic Encephalopathy, Boston University School of Medicine, Boston, MA, USA
    J Neuropathol Exp Neurol 68:709-35. 2009
    ..Deposition of beta-amyloid, most commonly as diffuse plaques, occurs in fewer than half the cases. Chronic traumatic encephalopathy is a neuropathologically distinct slowly progressive tauopathy with a clear environmental etiology...
  27. pmc Preserved frontal memorial processing for pictures in patients with mild cognitive impairment
    Brandon A Ally
    Center for Translational Cognitive Neuroscience, Geriatric Research Education Clinical Center, Bedford VA Hospital, Bedford, MA 01730, USA
    Neuropsychologia 47:2044-55. 2009
    ..Further, the authors address the possibility that enhanced retrieval monitoring may be needed to modulate increased familiarity engendered by pictures...
  28. pmc An evaluation of recollection and familiarity in Alzheimer's disease and mild cognitive impairment using receiver operating characteristics
    Brandon A Ally
    Center for Translational Cognitive Neuroscience, Geriatric Research Education Clinical Center, Bedford VA Hospital, Bedford, MA 01730, USA
    Brain Cogn 69:504-13. 2009
    ..The authors highlight differences in stimuli type and task difficulty as possibly modulating the ability of these patients to successfully use familiarity in support of memorial decisions...
  29. pmc Parietal contributions to recollection: electrophysiological evidence from aging and patients with parietal lesions
    Brandon A Ally
    Center for Translational Cognitive Neuroscience, Geriatric Research Education Clinical Center, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, MA 01730, USA
    Neuropsychologia 46:1800-12. 2008
    ..From these results, the authors speculate that the parietal old/new effect may be the neural correlate of an individual's subjective recollective experience...
  30. ncbi request reprint Sensory gating in patients with Alzheimer's disease and their biological children
    Brandon A Ally
    Edith Nourse Rogers Memorial Veteran s Hospital, GRECC, Bedford, Massachusetts 01730, USA
    Am J Alzheimers Dis Other Demen 21:439-47. 2006
    ..These results are discussed in relation to previous findings reporting P300 abnormalities in the FH+ group...
  31. pmc The worth of pictures: using high density event-related potentials to understand the memorial power of pictures and the dynamics of recognition memory
    Brandon A Ally
    Geriatric Research Education Clinical Center, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, MA 01730, USA
    Neuroimage 35:378-95. 2007
    ..From these results and the dynamic view of memory afforded by viewing the data as video clips, the authors propose an ERP model of recognition memory...
  32. ncbi request reprint Semantic versus phonological false recognition in aging and Alzheimer's disease
    Andrew E Budson
    Division of Cognitive and Behavioral Neurology, Brigham and Women s Hospital and Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA
    Brain Cogn 51:251-61. 2003
    ....
  33. ncbi request reprint Late frontal brain potentials distinguish true and false recognition
    Rachel E Goldmann
    Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA
    Neuroreport 14:1717-20. 2003
    ....
  34. ncbi request reprint Use of IQ-adjusted norms to predict progressive cognitive decline in highly intelligent older individuals
    Dorene M Rentz
    Division of Cognitive and Behavioral Neurology, Department of Neurology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Neuropsychology 18:38-49. 2004
    ..Three participants with normal memory declined. Implications for using IQ-adjusted norms to predict preclinical AD are discussed...
  35. ncbi request reprint Memory and emotions for the september 11, 2001, terrorist attacks in patients with Alzheimer's disease, patients with mild cognitive impairment, and healthy older adults
    Andrew E Budson
    Division of Cognitive and Behavioral Neurology, Department of Neurology, Brigham and Women s Hospital, Boston, MA 02115, USA
    Neuropsychology 18:315-27. 2004
    ..Last, distortions of memory for personal information were frequent for all participants but were more common in patients with AD...
  36. ncbi request reprint Metacognition and false recognition in Alzheimer's disease: further exploration of the distinctiveness heuristic
    Andrew E Budson
    Geriatric Research Education Center, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, MA, USA
    Neuropsychology 19:253-8. 2005
    ....
  37. ncbi request reprint Use of a false recognition paradigm in an Alzheimer's disease clinical trial: a pilot study
    Andrew E Budson
    Harvard Medical School, Boston, Massachusetts, USA
    Am J Alzheimers Dis Other Demen 17:93-100. 2002
    ..Because medications to treat AD may preferentially improve gist memory or item-specific recollection, use of this type of paradigm may improve sensitivity for detection of drug effects more than standard memory tests...
  38. ncbi request reprint Age-related differences in attention to novelty among cognitively high performing adults
    Kirk R Daffner
    Brigham Behavioral Neurology Group, Division of Cognitive and Behavioral Neurology, Department of Neurology, Brigham and Women s Hospital, Harvard Medical School, 221 Longwood Avenue, Boston, MA 02115, USA
    Biol Psychol 72:67-77. 2006
    ..We hypothesise that cognitively high performing old individuals successfully manage the task by relying on additional neural resources and perhaps more effortful frontal activity than their younger counterparts...
  39. ncbi request reprint False recognition of pictures versus words in Alzheimer's disease: the distinctiveness heuristic
    Andrew E Budson
    Department of Neurology, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Neuropsychology 16:163-73. 2002
    ..Implications for understanding semantic memory in AD patients are discussed...
  40. pmc Hippocampal hyperactivation in presymptomatic familial Alzheimer's disease
    Yakeel T Quiroz
    Department of Psychology, Center for Memory and Brain, Boston University, Boston, MA, USA
    Ann Neurol 68:865-75. 2010
    ..These PS1 subjects will go on to develop the first symptoms of the disease around the age of 45 years. Our objective was to examine hippocampal function years before the onset of clinical symptoms...
  41. pmc Increased T cell reactivity to amyloid beta protein in older humans and patients with Alzheimer disease
    Alon Monsonego
    Center for Neurologic Diseases, Harvard Medical School and Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    J Clin Invest 112:415-22. 2003
    ....
  42. ncbi request reprint Conceptual fluency at test shifts recognition response bias in Alzheimer's disease: implications for increased false recognition
    Carl A Gold
    Cognitive Neuroscience Laboratory, Geriatric Research Education Clinical Center, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, MA, USA
    Neuropsychologia 45:2791-801. 2007
    ..We speculate that AD patients' over reliance upon fluency may be attributable to (1) dysfunction of the hippocampus, disrupting recollection, and/or (2) dysfunction of prefrontal cortex, disrupting post-retrieval processes...
  43. ncbi request reprint Memory dysfunction
    Andrew E Budson
    Geriatric Research Education Clinical Center, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, Mass 01730, USA
    N Engl J Med 352:692-9. 2005
  44. ncbi request reprint Is the parietal lobe necessary for recollection in humans?
    Jon S Simons
    Brain Mapping Unit, University of Cambridge, Cambridge, UK
    Neuropsychologia 46:1185-91. 2008
    ..Thus, although the processes subserved by the human parietal lobe appear to be recruited to support memory function, they are not a necessary requirement for accurate remembering to occur...
  45. ncbi request reprint ERP correlates of Remember/Know decisions: association with the late posterior negativity
    David A Wolk
    Alzheimer s Disease Research Center, Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA
    Biol Psychol 75:131-5. 2007
    ..Previous work has described a late posterior negativity which appears to be related to the search for and recapitulation of study details. Such processing may be critical in making Remember/Know determinations...
  46. ncbi request reprint Overdependence on degraded gist memory in Alzheimer's disease
    David A Gallo
    Department of Psychology, University of Chicago, Chicago, IL 60637, USA
    Neuropsychology 20:625-32. 2006
    ..We propose that the overdependence on degraded gist memory in AD is caused by even larger impairments in item-specific recollections...
  47. ncbi request reprint ERP correlates of recognition memory: effects of retention interval and false alarms
    David A Wolk
    Department of Neurology, University of Pittsburgh, Kaufmann Medical Building, PA 15213, USA
    Brain Res 1096:148-62. 2006
    ..This latter result is discussed with regard to the possibility of an overlapping posterior negativity...
  48. ncbi request reprint Associative recognition in Alzheimer's disease: evidence for impaired recall-to-reject
    David A Gallo
    Department of Psychology, Harvard University, Cambridge, MA 02138, USA
    Neuropsychology 18:556-63. 2004
    ..AD impaired this recall-to-reject process, leading to more familiarity based false alarms. These data support the idea that recollection-based monitoring processes are impaired in mild AD...
  49. ncbi request reprint Failing to get the gist: reduced false recognition of semantic associates in semantic dementia
    Jon S Simons
    Institute of Cognitive Neuroscience, University College London, London, United Kingdom
    Neuropsychology 19:353-61. 2005
    ....
  50. ncbi request reprint Mis-attribution errors in Alzheimer's disease: the illusory truth effect
    Jason P Mitchell
    Harvard University, Cambridge, MA 02138, USA
    Neuropsychology 20:185-92. 2006
    ..These results help further specify the precise nature of memory impairments in AD...
  51. ncbi request reprint Comparing source-based and gist-based false recognition in aging and Alzheimer's disease
    Benton H Pierce
    Department of Psychology, Harvard University, MA, US
    Neuropsychology 19:411-9. 2005
    ..In contrast, false recognition in AD patients actually increased following the deep processing task, suggesting that they were unable to use recollection to oppose familiarity arising from incidental presentation...
  52. ncbi request reprint Retrieval monitoring and anosognosia in Alzheimer's disease
    David A Gallo
    Department of Psychology, University of Chicago, IL 60657, USA
    Neuropsychology 21:559-68. 2007
    ....
  53. ncbi request reprint Education and communication about memory: using the terminology of cognitive neuroscience
    Thomas H Glick
    Am J Alzheimers Dis Other Demen 20:141-3. 2005

Research Grants7

  1. MEMORY DISTORTION IN ALZHEIMER'S DISEASE
    ANDREW BUDSON; Fiscal Year: 2004
    ..The research conducted will advance our understanding of memory and its distortions in patients with AD, and may provide insights into encoding and retrieval in healthy individuals. ..
  2. Understanding False Recognition in Alzheimer's Disease
    ANDREW BUDSON; Fiscal Year: 2007
    ..Taken together, the proposed studies will provide new insights into memory in AD which may lead to improvements in our research and clinical care of patients with AD. ..
  3. Understanding False Recognition in Alzheimer's Disease
    ANDREW BUDSON; Fiscal Year: 2009
    ..Taken together, the proposed studies will provide new insights into memory in AD which may lead to improvements in our research and clinical care of patients with AD. ..