Emelia J Benjamin
Affiliation: Boston University
Benjamin E, Chen P, Bild D, Mascette A, Albert C, Alonso A, et al
. Prevention of atrial fibrillation: report from a national heart, lung, and blood institute workshop. Circulation. 2009;119:606-18 pubmed publisher
Kraja A, Chasman D, North K, Reiner A, Yanek L, Kilpeläinen T, et al
. Pleiotropic genes for metabolic syndrome and inflammation. Mol Genet Metab. 2014;112:317-38 pubmed publisher
..These findings warrant further functional investigation. ..
Christophersen I, Yin X, Larson M, Lubitz S, Magnani J, McManus D, et al
. A comparison of the CHARGE-AF and the CHA2DS2-VASc risk scores for prediction of atrial fibrillation in the Framingham Heart Study. Am Heart J. 2016;178:45-54 pubmed publisher
..71, 95% CI, 0.69-0.73), and better calibration (HL ?(2) = 5.6, P = .69 vs HL ?(2) = 28.5, P < .0001). The CHARGE-AF risk score performed better than the CHA2DS2-VASc risk score at predicting AF in a community-based cohort. ..
Rahman F, Yin X, Larson M, Ellinor P, Lubitz S, Vasan R, et al
. Trajectories of Risk Factors and Risk of New-Onset Atrial Fibrillation in the Framingham Heart Study. Hypertension. 2016;68:597-605 pubmed publisher
..Distinct trajectory groups with persistently elevated systolic BP and longer antihypertensive treatment are associated with increased risk of incident AF. ..
Lee J, Yin X, Hoffmann U, Fox C, Benjamin E. Relation of Pericardial Fat, Intrathoracic Fat, and Abdominal Visceral Fat With Incident Atrial Fibrillation (from the Framingham Heart Study). Am J Cardiol. 2016;118:1486-1492 pubmed publisher
..05). Our findings suggest that cardiac ectopic fat depots may share common risk factors with AF, which may have led to a lack of independence in the association between pericardial fat with incident AF. ..
Campion M, Bhasin R, Beaudette D, Shann M, Benjamin E. Mid-career faculty development in academic medicine: How does it impact faculty and institutional vitality?. J Fac Dev. 2016;30:49-64 pubmed
Benjamin E, Dupuis J, Larson M, Lunetta K, Booth S, Govindaraju D, et al
. Genome-wide association with select biomarker traits in the Framingham Heart Study. BMC Med Genet. 2007;8 Suppl 1:S11 pubmed
..cgi?id=phs000007 webcite. The Framingham GWAS represents a resource to describe potentially novel genetic influences on systemic biomarker variability. The newly described associations will need to be replicated in other studies. ..
Benjamin E, Rice K, Arking D, Pfeufer A, van Noord C, Smith A, et al
. Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry. Nat Genet. 2009;41:879-81 pubmed publisher
..19; P = 2.3 x 10(-7)). We replicated this association in an independent cohort from the German AF Network (odds ratio = 1.44; P = 1.6 x 10(-11); combined RR = 1.25; combined P = 1.8 x 10(-15)). ..