Michael J Baum

Summary

Affiliation: Boston University
Country: USA

Publications

  1. pmc Contribution of pheromones processed by the main olfactory system to mate recognition in female mammals
    Michael J Baum
    Department of Biology, Boston University, Boston MA, USA
    Front Neuroanat 6:20. 2012
  2. ncbi request reprint Roles of sex and gonadal steroids in mammalian pheromonal communication
    Michael J Baum
    Dept of Biology, Boston University, 5 Cummington St, Boston, MA 02215, USA Electronic address
    Front Neuroendocrinol 34:268-84. 2013
  3. ncbi request reprint Complementary roles of the main and accessory olfactory systems in mammalian mate recognition
    Michael J Baum
    Department of Biology, Boston University, Boston, Massachusetts 02215, USA
    Annu Rev Physiol 71:141-60. 2009
  4. ncbi request reprint Mammalian animal models of psychosexual differentiation: when is 'translation' to the human situation possible?
    Michael J Baum
    Department of Biology, Boston University, 5 Cummington Sreet, Boston, MA 02215, USA
    Horm Behav 50:579-88. 2006
  5. pmc Sexual differentiation of pheromone processing: links to male-typical mating behavior and partner preference
    Michael J Baum
    Department of Biology, Boston University, 5 Cummington St, Boston, MA 02215, USA
    Horm Behav 55:579-88. 2009
  6. ncbi request reprint Activational and organizational effects of estradiol on male behavioral neuroendocrine function
    Michael J Baum
    Department of Biology, Boston University, Boston, MA 02215, USA
    Scand J Psychol 44:213-20. 2003
  7. pmc Adult testosterone treatment but not surgical disruption of vomeronasal function augments male-typical sexual behavior in female mice
    Kristine L Martel
    Department of Biology, Boston University, Boston, Massachusetts 02215, USA
    J Neurosci 29:7658-66. 2009
  8. pmc A centrifugal pathway to the mouse accessory olfactory bulb from the medial amygdala conveys gender-specific volatile pheromonal signals
    Kristine L Martel
    Department of Biology, Boston University, Boston, MA 02215, USA
    Eur J Neurosci 29:368-76. 2009
  9. pmc A direct main olfactory bulb projection to the 'vomeronasal' amygdala in female mice selectively responds to volatile pheromones from males
    Ningdong Kang
    Department of Biology, Boston University, Boston, MA 02215, USA
    Eur J Neurosci 29:624-34. 2009
  10. pmc Accessory olfactory neural Fos responses to a conditioned environment are blocked in male mice by vomeronasal organ removal
    Diana E Pankevich
    Departments of Biology and Psychology, Boston University, 5 Cummington Street, Boston, MA 02215, USA
    Physiol Behav 87:781-8. 2006

Research Grants

  1. SEXUAL DIFFERENTIATION OF MOUSE VOMERONASAL FUNCTION
    Michael Baum; Fiscal Year: 1999
  2. Contribution of Estradiol to Female Neural Development
    Michael Baum; Fiscal Year: 2006
  3. Contribution of Estradiol to Female Neural Development
    Michael Baum; Fiscal Year: 2007
  4. DIFFERENTIATION OF SEXUAL BEHAVIOR
    Michael Baum; Fiscal Year: 2005
  5. Contribution of Estradiol to Female Neural Development
    Michael Baum; Fiscal Year: 2005
  6. Contribution of Estradiol to Female Neural Development
    Michael Baum; Fiscal Year: 2004
  7. DIFFERENTIATION OF SEXUAL BEHAVIOR
    Michael Baum; Fiscal Year: 2004
  8. Contribution of Estradiol to Female Neural Development
    Michael Baum; Fiscal Year: 2003
  9. DIFFERENTIATION OF SEXUAL BEHAVIOR
    Michael Baum; Fiscal Year: 2003
  10. DIFFERENTIATION OF SEXUAL BEHAVIOR
    Michael Baum; Fiscal Year: 2001

Collaborators

Detail Information

Publications33

  1. pmc Contribution of pheromones processed by the main olfactory system to mate recognition in female mammals
    Michael J Baum
    Department of Biology, Boston University, Boston MA, USA
    Front Neuroanat 6:20. 2012
    ..Behavioral data from female mouse, ferret, and human are reviewed that implicate the main olfactory system, in some cases interacting with the accessory olfactory system, in mate recognition...
  2. ncbi request reprint Roles of sex and gonadal steroids in mammalian pheromonal communication
    Michael J Baum
    Dept of Biology, Boston University, 5 Cummington St, Boston, MA 02215, USA Electronic address
    Front Neuroendocrinol 34:268-84. 2013
    ..Persisting questions about the role of sex steroids in pheromonal processing are posed for future investigation. ..
  3. ncbi request reprint Complementary roles of the main and accessory olfactory systems in mammalian mate recognition
    Michael J Baum
    Department of Biology, Boston University, Boston, Massachusetts 02215, USA
    Annu Rev Physiol 71:141-60. 2009
    ..Finally, we review experiments that raise the possibility that body odorants detected by the main olfactory system contribute to mate recognition in humans...
  4. ncbi request reprint Mammalian animal models of psychosexual differentiation: when is 'translation' to the human situation possible?
    Michael J Baum
    Department of Biology, Boston University, 5 Cummington Sreet, Boston, MA 02215, USA
    Horm Behav 50:579-88. 2006
    ..I also argue, however, that results of animal studies can, at best, provide only indirect insights into the neuroendocrine determinants of human gender identity and role behaviors...
  5. pmc Sexual differentiation of pheromone processing: links to male-typical mating behavior and partner preference
    Michael J Baum
    Department of Biology, Boston University, 5 Cummington St, Boston, MA 02215, USA
    Horm Behav 55:579-88. 2009
    ....
  6. ncbi request reprint Activational and organizational effects of estradiol on male behavioral neuroendocrine function
    Michael J Baum
    Department of Biology, Boston University, Boston, MA 02215, USA
    Scand J Psychol 44:213-20. 2003
    ..Evidence is also reviewed suggesting that perinatal estradiol biosynthesis and action in the female's nervous system may contribute to the development of female-typical sexual behavior...
  7. pmc Adult testosterone treatment but not surgical disruption of vomeronasal function augments male-typical sexual behavior in female mice
    Kristine L Martel
    Department of Biology, Boston University, Boston, Massachusetts 02215, USA
    J Neurosci 29:7658-66. 2009
    ..However, we failed to corroborate the recent claim that VNO signaling normally inhibits the activity of neural circuitry controlling the expression of male-typical mating behavior by female mice...
  8. pmc A centrifugal pathway to the mouse accessory olfactory bulb from the medial amygdala conveys gender-specific volatile pheromonal signals
    Kristine L Martel
    Department of Biology, Boston University, Boston, MA 02215, USA
    Eur J Neurosci 29:368-76. 2009
    ..Main olfactory-MeA-AOB signaling may motivate approach behaviour to opposite-sex pheromonal signals that ensure successful reproduction...
  9. pmc A direct main olfactory bulb projection to the 'vomeronasal' amygdala in female mice selectively responds to volatile pheromones from males
    Ningdong Kang
    Department of Biology, Boston University, Boston, MA 02215, USA
    Eur J Neurosci 29:624-34. 2009
    ..The presence of a direct MOB-to-medial amygdala pathway in mice and other mammals could enable volatile, opposite-sex pheromones to gain privileged access to diencephalic structures that control mate recognition and reproduction...
  10. pmc Accessory olfactory neural Fos responses to a conditioned environment are blocked in male mice by vomeronasal organ removal
    Diana E Pankevich
    Departments of Biology and Psychology, Boston University, 5 Cummington Street, Boston, MA 02215, USA
    Physiol Behav 87:781-8. 2006
    ..These results suggest that activity in distal segments of the VNO-accessory olfactory pathway, in addition to the mesolimbic dopamine reward system, can be conditioned to respond to non-odor cues...
  11. pmc Enhanced urinary odor discrimination in female aromatase knockout (ArKO) mice
    Daniel W Wesson
    Department of Biology, Boston University, Boston, MA 02215, USA
    Horm Behav 49:580-6. 2006
    ....
  12. pmc Bilateral damage to the sexually dimorphic medial preoptic area/anterior hypothalamus of male ferrets causes a female-typical preference for and a hypothalamic Fos response to male body odors
    Olga V Alekseyenko
    Department of Biology, 5 Cummington St, Boston, MA 02215, USA
    Physiol Behav 90:438-49. 2007
    ..Male-typical hypothalamic processing of conspecifics' body odorants may determine males' normal preference to seek out odors emitted by female conspecifics, leading to mating and successful reproduction...
  13. pmc Effect of vomeronasal organ removal from male mice on their preference for and neural Fos responses to female urinary odors
    Diana E Pankevich
    Department of Biology, Boston University, Boston, MA 02215, USA
    Behav Neurosci 120:925-36. 2006
    ..However, once direct nasal contact is made with female urine, VNO inputs further activate forebrain mechanisms that amplify the reward salience of this stimulus for the male mouse...
  14. pmc Disruption of urinary odor preference and lordosis behavior in female mice given lesions of the medial amygdala
    Brett T Dibenedictis
    Department of Biology, Boston University, Boston, MA 02215, United States
    Physiol Behav 105:554-9. 2012
    ..Our results suggest that the Me is a critical segment of the olfactory circuit that controls both mate recognition and mating behavior in the female mouse...
  15. pmc Sexually dimorphic enhancement by estradiol of male urinary odor detection thresholds in mice
    Krystina G Sorwell
    Department of Biology, Boston University, Boston, MA 02215, USA
    Behav Neurosci 122:788-93. 2008
    ..Thus, estradiol enhanced detection thresholds for male urine in a sex-specific manner, and this enhanced sensitivity in females was correlated with altered odor-sampling behavior...
  16. pmc Sexually dimorphic activation of the accessory, but not the main, olfactory bulb in mice by urinary volatiles
    Kristine L Martel
    Department of Biology, Boston University, 5 Cummington Street, Boston, MA 02215, USA
    Eur J Neurosci 26:463-75. 2007
    ..Future studies will determine whether MOE or VNO signaling, or both types of input, drive the sexually dimorphic response of the AOB to volatile opposite-sex odours and whether this AOB response contributes to reproductive success...
  17. pmc Effect of bilateral accessory olfactory bulb lesions on volatile urinary odor discrimination and investigation as well as mating behavior in male mice
    Jasmina Jakupovic
    Department of Biology, Boston University, Boston, MA 02215, USA
    Physiol Behav 93:467-73. 2008
    ..Our results suggest that the incentive value of opposite-sex (female) volatile urinary odors which are initially detected by the main olfactory system is enhanced when they are further processed by the male's AOB...
  18. pmc Ventromedial hypothalamic nucleus lesions disrupt olfactory mate recognition and receptivity in female ferrets
    Daniel W Robarts
    Department of Biology, Boston University, Boston, MA 02215, USA
    Horm Behav 51:104-13. 2007
    ..Estrogen-sensitive neurons in the VMH appear to play a central role in female-typical neural processing of odor inputs leading to a preference to seek out a male sex partner, in addition to facilitating females' sexual receptivity...
  19. ncbi request reprint Sex difference in Fos induced by male urine in medial amygdala-projecting accessory olfactory bulb mitral cells of mice
    Ningdong Kang
    Department of Biology, Boston University, Boston, MA 02215, USA
    Neurosci Lett 398:59-62. 2006
    ....
  20. pmc Different profiles of main and accessory olfactory bulb mitral/tufted cell projections revealed in mice using an anterograde tracer and a whole-mount, flattened cortex preparation
    Ningdong Kang
    Department of Biology, Boston University, Boston, MA 02215, USA
    Chem Senses 36:251-60. 2011
    ..This arrangement may be related to the ability of social experience to modify the response of mice to volatile pheromones detected by the main olfactory system...
  21. pmc Differential activation of glomeruli in the ferret's main olfactory bulb by anal scent gland odours from males and females: an early step in mate identification
    Sarah K Woodley
    Department of Biology, Boston University, 5 Cummington St, Boston, MA 02215, USA
    Eur J Neurosci 20:1025-32. 2004
    ..In ferrets of both sexes, volatile body odourants that are detected by the main as opposed to the vomeronasal-AOB accessory olfactory system may play a critical role in mate identification...
  22. ncbi request reprint Sex difference in the distribution and size of glomeruli in the ferret's main olfactory bulb
    Patricia Waters
    Department of Biology, Boston University, 5 Cummington St, Boston, MA 02215, USA
    Neurosci Lett 381:237-41. 2005
    ..This functional sex difference was inversely correlated with the present observation that glomerular density, number and area were greater in the caudal MOB of male than female ferrets...
  23. ncbi request reprint Olfactory sex discrimination persists, whereas the preference for urinary odorants from estrous females disappears in male mice after vomeronasal organ removal
    Diana E Pankevich
    Department of Biology, Boston University, Boston, Massachusetts 02215, USA
    J Neurosci 24:9451-7. 2004
    ..Our results suggest that the VNO is not required for sex discrimination but instead detects the nonvolatile components of opposite-sex urine that may be used to help prolong contact with individuals that produce these chemosignals...
  24. ncbi request reprint Effects of sex hormones and gender on attraction thresholds for volatile anal scent gland odors in ferrets
    Sarah K Woodley
    Department of Biology, Boston University, Boston, MA 02215, USA
    Horm Behav 44:110-8. 2003
    ..These data suggest that ferrets could use anal scent gland secretions in mate recognition and that seasonal increases in circulating sex steroid hormones increase ferrets' responsiveness to low concentrations of these odors...
  25. pmc A quantitative comparison of the efferent projections of the anterior and posterior subdivisions of the medial amygdala in female mice
    Brett T Dibenedictis
    Department of Biology, Boston University, Boston, MA 02215, United States
    Brain Res 1543:101-8. 2014
    ....
  26. ncbi request reprint Effect of prenatal androgen receptor antagonist or aromatase inhibitor on sexual behavior, partner preference and neuronal Fos responses to estrous female odors in the rat accessory olfactory system
    Emilio Dominguez-Salazar
    Centro de Neurobiologia, Universidad Nacional Autonoma de Mexico, Qro 76230, Queretaro, Mexico
    Physiol Behav 75:337-46. 2002
    ....
  27. doi request reprint Building a scientific framework for studying hormonal effects on behavior and on the development of the sexually dimorphic nervous system
    Abby A Li
    Exponent Health Sciences, San Francisco, CA 94114, USA
    Neurotoxicology 29:504-19. 2008
    ..Understanding of the hormonal mechanisms of these behaviors, and of relevance to humans, is needed to develop biologically plausible hypotheses regarding the potential effects of hormonally active chemicals in humans...
  28. pmc Role for estradiol in female-typical brain and behavioral sexual differentiation
    Julie Bakker
    Center for Cellular and Molecular Neurobiology, University of Liege, Belgium
    Front Neuroendocrinol 29:1-16. 2008
    ....
  29. ncbi request reprint Male aromatase knockout mice acquire a conditioned place preference for cocaine but not for contact with an estrous female
    Sylvie Pierman
    Center for Cellular and Molecular Neurobiology, University of Liege, Avenue de l Hopital 1, B36, 4000 Liege, Belgium
    Behav Brain Res 174:64-9. 2006
    ..These results thus further confirm the important role of estradiol in sexually related behavioral responses in male mice...
  30. pmc Destruction of the main olfactory epithelium reduces female sexual behavior and olfactory investigation in female mice
    Matthieu Keller
    Behavioral Neuroendocrinology, Center for Cellular and Molecular Neurobiology, University of Liege, Liege Sart Tilman, Belgium
    Chem Senses 31:315-23. 2006
    ..By contrast, both the main and accessory olfactory systems contribute to female sexual receptivity in female mice...
  31. pmc The vomeronasal organ is required for the expression of lordosis behaviour, but not sex discrimination in female mice
    Matthieu Keller
    Centre for Cellular and Molecular Neurobiology, Research Group in Behavioural Neuroendocrinology, University of Liege, Belgium
    Eur J Neurosci 23:521-30. 2006
    ....
  32. ncbi request reprint Attraction thresholds and sex discrimination of urinary odorants in male and female aromatase knockout (ArKO) mice
    Sylvie Pierman
    Center for Cellular and Molecular Neurobiology, University of Liege, Belgium
    Horm Behav 49:96-104. 2006
    ....
  33. pmc A possible role for imprinted genes in inbreeding avoidance and dispersal from the natal area in mice
    Anthony R Isles
    Sub Department of Animal Behaviour, University of Cambridge, Madingley, Cambridge CB3 8AA, UK
    Proc Biol Sci 269:665-70. 2002
    ....

Research Grants16

  1. SEXUAL DIFFERENTIATION OF MOUSE VOMERONASAL FUNCTION
    Michael Baum; Fiscal Year: 1999
    ..The results of these experiments should identify sites in a well-characterized anatomical pathway at which sex hormones and social experience affect the detection and/or processing of olfactory signals. ..
  2. Contribution of Estradiol to Female Neural Development
    Michael Baum; Fiscal Year: 2006
    ..The proposed studies should provide new information about the contribution of estradiol to the development of essential aspects of female-typical neural and behavioral functions. ..
  3. Contribution of Estradiol to Female Neural Development
    Michael Baum; Fiscal Year: 2007
    ..Affirmation of a perinatal role for estradiol in brain sexual differentiation in female mice would raise the question of whether estradiol plays a similar role in female-typical psychosexual differentiation in women. ..
  4. DIFFERENTIATION OF SEXUAL BEHAVIOR
    Michael Baum; Fiscal Year: 2005
    ..abstract_text> ..
  5. Contribution of Estradiol to Female Neural Development
    Michael Baum; Fiscal Year: 2005
    ..The proposed studies should provide new information about the contribution of estradiol to the development of essential aspects of female-typical neural and behavioral functions. ..
  6. Contribution of Estradiol to Female Neural Development
    Michael Baum; Fiscal Year: 2004
    ..The proposed studies should provide new information about the contribution of estradiol to the development of essential aspects of female-typical neural and behavioral functions. ..
  7. DIFFERENTIATION OF SEXUAL BEHAVIOR
    Michael Baum; Fiscal Year: 2004
    ..abstract_text> ..
  8. Contribution of Estradiol to Female Neural Development
    Michael Baum; Fiscal Year: 2003
    ..The proposed studies should provide new information about the contribution of estradiol to the development of essential aspects of female-typical neural and behavioral functions. ..
  9. DIFFERENTIATION OF SEXUAL BEHAVIOR
    Michael Baum; Fiscal Year: 2003
    ..abstract_text> ..
  10. DIFFERENTIATION OF SEXUAL BEHAVIOR
    Michael Baum; Fiscal Year: 2001
    ..Understanding how the male and female nervous systems process reproductive odors differently in a higher mammal like the ferret could provide new insights into sexually dimorphic brain-behavior relationships in man. ..
  11. SEXUAL DIFFERENTIATION OF MOUSE VOMERONASAL FUNCTION
    Michael Baum; Fiscal Year: 2001
    ..The results of these experiments should identify sites in a well-characterized anatomical pathway at which sex hormones and social experience affect the detection and/or processing of olfactory signals. ..
  12. DIFFERENTIATION OF SEXUAL BEHAVIOR
    Michael Baum; Fiscal Year: 2000
    ..Understanding how the male and female nervous systems process reproductive odors differently in a higher mammal like the ferret could provide new insights into sexually dimorphic brain-behavior relationships in man. ..
  13. SEXUAL DIFFERENTIATION OF MOUSE VOMERONASAL FUNCTION
    Michael Baum; Fiscal Year: 2000
    ..The results of these experiments should identify sites in a well-characterized anatomical pathway at which sex hormones and social experience affect the detection and/or processing of olfactory signals. ..
  14. DIFFERENTIATION OF SEXUAL BEHAVIOR
    Michael Baum; Fiscal Year: 1999
    ..Understanding how the male and female nervous systems process reproductive odors differently in a higher mammal like the ferret could provide new insights into sexually dimorphic brain-behavior relationships in man. ..
  15. Contribution of Estradiol to Female Neural Development
    Michael Baum; Fiscal Year: 2009
    ..Affirmation of a perinatal role for estradiol in brain sexual differentiation in female mice would raise the question of whether estradiol plays a similar role in female-typical psychosexual differentiation in women. ..