H Barbas

Summary

Affiliation: Boston University
Country: USA

Publications

  1. ncbi Cortical structure predicts the pattern of corticocortical connections
    H Barbas
    Department of Health Sciences, Boston University, MA 02215, USA
    Cereb Cortex 7:635-46. 1997
  2. ncbi Specialized elements of orbitofrontal cortex in primates
    Helen Barbas
    Department of Health Sciences, Program in Neuroscience, Boston University, Boston, MA 02215, USA
    Ann N Y Acad Sci 1121:10-32. 2007
  3. ncbi The prefrontal cortex and flexible behavior
    Helen Barbas
    Department of Health Sciences, Commonwealth Ave, Room 431, Boston, MA 02215, USA
    Neuroscientist 13:532-45. 2007
  4. ncbi Parallel organization of contralateral and ipsilateral prefrontal cortical projections in the rhesus monkey
    Helen Barbas
    Department of Health Sciences, Boston University, Boston, MA, USA
    BMC Neurosci 6:32. 2005
  5. ncbi Relationship of prefrontal connections to inhibitory systems in superior temporal areas in the rhesus monkey
    H Barbas
    Department of Health Sciences, Boston University, Boston, MA 02215, USA
    Cereb Cortex 15:1356-70. 2005
  6. ncbi Sensory pathways and emotional context for action in primate prefrontal cortex
    Helen Barbas
    Neural Systems Laboratory, Boston University and School of Medicine, Boston, MA 02215, USA
    Biol Psychiatry 69:1133-9. 2011
  7. ncbi Dead tissue, living ideas: facts and theory from neuroanatomy
    Helen Barbas
    Dept. of Health Sciences, Boston University, MA, USA
    Cortex 40:205-6. 2004
  8. ncbi Serial pathways from primate prefrontal cortex to autonomic areas may influence emotional expression
    Helen Barbas
    Department of Health Sciences, Boston University, Boston, MA 02215, USA
    BMC Neurosci 4:25. 2003
  9. ncbi Flow of information for emotions through temporal and orbitofrontal pathways
    Helen Barbas
    Department of Health Sciences, Boston University, 635 Commonwealth Ave, Room 431, Boston, MA 02215, USA
    J Anat 211:237-49. 2007
  10. ncbi Medial prefrontal cortices are unified by common connections with superior temporal cortices and distinguished by input from memory-related areas in the rhesus monkey
    H Barbas
    Department of Health Sciences, Boston University, Massachusetts 02215, USA
    J Comp Neurol 410:343-67. 1999

Research Grants

  1. ORGANIZATION OF PREFRONTAL FEEDBACK CIRCUITS
    Helen Barbas; Fiscal Year: 2009
  2. Prefrontal anatomic pathways in executive control
    Helen Barbas; Fiscal Year: 2009
  3. Prefrontal anatomic pathways in executive control
    Helen Barbas; Fiscal Year: 2010
  4. Prefrontal anatomic pathways in executive control
    Helen Barbas; Fiscal Year: 2004
  5. ANATOMY OF LIMBIC PREFRONTAL CORTEX
    Helen Barbas; Fiscal Year: 2000
  6. ORGANIZATION OF PREFRONTAL FEEDBACK CIRCUITS
    Helen Barbas; Fiscal Year: 2003
  7. ORGANIZATION OF PREFRONTAL FEEDBACK CIRCUITS
    Helen Barbas; Fiscal Year: 2010

Collaborators

Detail Information

Publications31

  1. ncbi Cortical structure predicts the pattern of corticocortical connections
    H Barbas
    Department of Health Sciences, Boston University, MA 02215, USA
    Cereb Cortex 7:635-46. 1997
    ..The power of this structural model lies in its potential to predict patterns of connections in the human cortex, where invasive procedures are precluded...
  2. ncbi Specialized elements of orbitofrontal cortex in primates
    Helen Barbas
    Department of Health Sciences, Program in Neuroscience, Boston University, Boston, MA 02215, USA
    Ann N Y Acad Sci 1121:10-32. 2007
    ..Pathology in orbitofrontal cortex may remove feedback input to sensory cortices, dissociating emotional context from sensory content and impairing the ability to interpret events...
  3. ncbi The prefrontal cortex and flexible behavior
    Helen Barbas
    Department of Health Sciences, Commonwealth Ave, Room 431, Boston, MA 02215, USA
    Neuroscientist 13:532-45. 2007
    ..Circuit-based models suggest that prefrontal pathways can select relevant signals and efficiently suppress distractors, in processes that are disrupted in schizophrenia and in other disorders affecting prefrontal cortices...
  4. ncbi Parallel organization of contralateral and ipsilateral prefrontal cortical projections in the rhesus monkey
    Helen Barbas
    Department of Health Sciences, Boston University, Boston, MA, USA
    BMC Neurosci 6:32. 2005
    ....
  5. ncbi Relationship of prefrontal connections to inhibitory systems in superior temporal areas in the rhesus monkey
    H Barbas
    Department of Health Sciences, Boston University, Boston, MA 02215, USA
    Cereb Cortex 15:1356-70. 2005
    ..These findings may help explain the reduced efficacy of inhibitory control in superior temporal areas after prefrontal cortical damage...
  6. ncbi Sensory pathways and emotional context for action in primate prefrontal cortex
    Helen Barbas
    Neural Systems Laboratory, Boston University and School of Medicine, Boston, MA 02215, USA
    Biol Psychiatry 69:1133-9. 2011
    ....
  7. ncbi Dead tissue, living ideas: facts and theory from neuroanatomy
    Helen Barbas
    Dept. of Health Sciences, Boston University, MA, USA
    Cortex 40:205-6. 2004
  8. ncbi Serial pathways from primate prefrontal cortex to autonomic areas may influence emotional expression
    Helen Barbas
    Department of Health Sciences, Boston University, Boston, MA 02215, USA
    BMC Neurosci 4:25. 2003
    ..The latter innervate peripheral autonomic organs, whose activity is markedly increased during emotional arousal...
  9. ncbi Flow of information for emotions through temporal and orbitofrontal pathways
    Helen Barbas
    Department of Health Sciences, Boston University, 635 Commonwealth Ave, Room 431, Boston, MA 02215, USA
    J Anat 211:237-49. 2007
    ..These laminar-specific pathways suggest sequential and collaborative interactions in evaluating the sensory and emotional aspects of the environment for decision and action in complex behaviour...
  10. ncbi Medial prefrontal cortices are unified by common connections with superior temporal cortices and distinguished by input from memory-related areas in the rhesus monkey
    H Barbas
    Department of Health Sciences, Boston University, Massachusetts 02215, USA
    J Comp Neurol 410:343-67. 1999
    ..Auditory pathways may have a role in the specialization of medial prefrontal cortices in species-specific communication in non-human primates and language functions in humans...
  11. ncbi Connections underlying the synthesis of cognition, memory, and emotion in primate prefrontal cortices
    H Barbas
    Department of Health Sciences, Boston University and Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA 02215, USA
    Brain Res Bull 52:319-30. 2000
    ....
  12. ncbi Specificity in inhibitory systems associated with prefrontal pathways to temporal cortex in primates
    M Medalla
    Departments of Health Sciences, Boston University, School of Medicine, MA 02215, USA
    Cereb Cortex 17:i136-50. 2007
    ..These findings suggest diversity in inhibitory control by distinct prefrontal pathways...
  13. ncbi Pathways for emotion: interactions of prefrontal and anterior temporal pathways in the amygdala of the rhesus monkey
    H T Ghashghaei
    Department of Health Sciences, Boston University, 635 Commonwealth Avenue, Room 431, Boston, MA 02215, USA
    Neuroscience 115:1261-79. 2002
    ..This intricate network may be recruited in cognitive tasks that are inextricably linked with emotional associations...
  14. ncbi Diversity of laminar connections linking periarcuate and lateral intraparietal areas depends on cortical structure
    M Medalla
    Department of Health Sciences, Boston University, 635 Commonwealth Ave. Room 431, Boston, MA 02215, USA
    Eur J Neurosci 23:161-79. 2006
    ..These findings indicate that the neuronal density of linked areas can reliably predict their laminar connections and may form the basis of understanding the functional complexity of prefrontal-intraparietal interactions in cognition...
  15. ncbi Quantitative architecture distinguishes prefrontal cortical systems in the rhesus monkey
    S M Dombrowski
    Department of Behavioral Neuroscience, Boston University School of Medicine, Boston, MA, USA
    Cereb Cortex 11:975-88. 2001
    ....
  16. ncbi Sequence of information processing for emotions based on the anatomic dialogue between prefrontal cortex and amygdala
    H T Ghashghaei
    Boston University, Boston University School of Medicine, Boston, MA 02215, USA
    Neuroimage 34:905-23. 2007
    ....
  17. ncbi Laminar and modular organization of prefrontal projections to multiple thalamic nuclei
    D Xiao
    Program in Neuroscience, Boston University, Boston, MA 02215, USA
    Neuroscience 161:1067-81. 2009
    ..These pathways may underlie the synthesis of cognition, emotion and action...
  18. ncbi Topographic organization of connections between the hypothalamus and prefrontal cortex in the rhesus monkey
    N L Rempel-Clower
    Department of Health Sciences, Boston University, Massachusetts 02215, USA
    J Comp Neurol 398:393-419. 1998
    ..These results suggest that specific orbitofrontal and medial prefrontal areas exert a direct influence on the hypothalamus and may be important for the autonomic responses evoked by complex emotional situations...
  19. ncbi Neural interaction between the basal forebrain and functionally distinct prefrontal cortices in the rhesus monkey
    H T Ghashghaei
    Department of Health Sciences, Boston University, 635 Commonwealth Ave, Boston, MA 02215, USA
    Neuroscience 103:593-614. 2001
    ..Moreover, orbitofrontal and medial prefrontal cortices target the ventral pallidum and the extended amygdala, through which high-order association areas may activate motor autonomic structures for the expression of emotions...
  20. ncbi Synapses with inhibitory neurons differentiate anterior cingulate from dorsolateral prefrontal pathways associated with cognitive control
    Maria Medalla
    Department of Health Sciences, Boston University and School of Medicine, Boston, MA 02215, USA
    Neuron 61:609-20. 2009
    ..These observations highlight the unique roles of the DLPFC and ACC in cognitive control...
  21. ncbi Sequence of information processing for emotions through pathways linking temporal and insular cortices with the amygdala
    Malin Höistad
    Neural Systems Laboratory, Department of Health Sciences, Boston University, 635 Commonwealth Avenue, Boston, MA 02215, USA
    Neuroimage 40:1016-33. 2008
    ..These findings may help explain how the amygdala can attach emotional value to environmental stimuli, participate in the sequence of information processing of emotions, and modulate the formation of emotional memories...
  22. ncbi Mitochondrial degeneration in dystrophic neurites of senile plaques may lead to extracellular deposition of fine filaments
    John C Fiala
    Department of Health Sciences, Boston University, 635 Commonwealth Ave, Boston, MA 02215, USA
    Brain Struct Funct 212:195-207. 2007
    ..This progression of degeneration suggests that extracellular filaments originate inside degenerating mitochondria of neuritic diverticula, which may be a common process in diverse diseases...
  23. ncbi Synaptic distinction of laminar-specific prefrontal-temporal pathways in primates
    Michael Germuska
    Department of Biomedical Engineering, Boston University and School of Medicine, Boston, MA, USA
    Cereb Cortex 16:865-75. 2006
    ..This synaptic distinction suggests differences in efficacy of synaptic transmission and metabolic demands in laminar-specific pathways that may be selectively recruited in behavior...
  24. ncbi Effects of normal aging on prefrontal area 46 in the rhesus monkey
    Jennifer Luebke
    Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA, USA
    Brain Res Rev 62:212-32. 2010
    ..These factors contribute to alterations in the intrinsic and network physiological properties of cortical neurons. As more details emerge, it is to be hoped that effective interventions to retard cognitive decline can be proposed...
  25. ncbi Prefrontal projections to the thalamic reticular nucleus form a unique circuit for attentional mechanisms
    Basilis Zikopoulos
    Department of Health Sciences, Boston University, Boston, Massachusetts 02215, USA
    J Neurosci 26:7348-61. 2006
    ..The targeting of sensory tiers of TRN by specific prefrontal areas may underlie attentional regulation for the selection of relevant sensory signals and suppression of distractors...
  26. ncbi Parallel driving and modulatory pathways link the prefrontal cortex and thalamus
    Basilis Zikopoulos
    Department of Health Sciences, Boston University, Boston, Massachusetts, United States of America
    PLoS ONE 2:e848. 2007
    ..The balance of activation of these parallel circuits that link a high-order association cortex with the thalamus may allow shifts to different states of consciousness, in processes that are disrupted in psychiatric diseases...
  27. ncbi Circuits formultisensory integration and attentional modulation through the prefrontal cortex and the thalamic reticular nucleus in primates
    Basilis Zikopoulos
    Department of Health Sciences, Boston University, MA 02215, USA
    Rev Neurosci 18:417-38. 2007
    ..We propose a model showing that the specialized features of prefrontal pathways in the reticular nucleus may allow selection of relevant information and override distractors, in processes that are deranged in schizophrenia...
  28. ncbi Changes in prefrontal axons may disrupt the network in autism
    Basilis Zikopoulos
    Neural Systems Laboratory, Boston University, Boston, Massachusetts 02215, USA
    J Neurosci 30:14595-609. 2010
    ....
  29. ncbi Developmental mechanics of the primate cerebral cortex
    Claus C Hilgetag
    School of Eng and Science, Internat l Univ Bremen, Campus Ring 6, RII 116, 28759 Bremen, Germany
    Anat Embryol (Berl) 210:411-7. 2005
    ....
  30. ncbi Role of mechanical factors in the morphology of the primate cerebral cortex
    Claus C Hilgetag
    School of Engineering and Science, International University Bremen, Bremen, Germany
    PLoS Comput Biol 2:e22. 2006
    ..Such models are particularly relevant for understanding the relationship of cortical morphology to the connectivity of normal brains, and structurally altered brains in diseases of developmental origin, such as schizophrenia and autism...
  31. ncbi Late granule cell genesis in quail cerebellum
    Antonis Stamatakis
    Department of Biology, University of Crete, Heraklion 714 09, Crete, Greece
    J Comp Neurol 474:173-89. 2004
    ..The index of granule cell production and survival supports a spatiotemporal pattern, in correlation with the functional division of cerebellum into anterior and posterior domains...

Research Grants23

  1. ORGANIZATION OF PREFRONTAL FEEDBACK CIRCUITS
    Helen Barbas; Fiscal Year: 2009
    ..abstract_text> ..
  2. Prefrontal anatomic pathways in executive control
    Helen Barbas; Fiscal Year: 2009
    ..abstract_text> ..
  3. Prefrontal anatomic pathways in executive control
    Helen Barbas; Fiscal Year: 2010
    ....
  4. Prefrontal anatomic pathways in executive control
    Helen Barbas; Fiscal Year: 2004
    ..abstract_text> ..
  5. ANATOMY OF LIMBIC PREFRONTAL CORTEX
    Helen Barbas; Fiscal Year: 2000
    ....
  6. ORGANIZATION OF PREFRONTAL FEEDBACK CIRCUITS
    Helen Barbas; Fiscal Year: 2003
    ..abstract_text> ..
  7. ORGANIZATION OF PREFRONTAL FEEDBACK CIRCUITS
    Helen Barbas; Fiscal Year: 2010
    ....