Xingbin Ai

Summary

Affiliation: Boston University
Country: USA

Publications

  1. pmc Mechanisms of respiratory innervation during embryonic development
    Linh Aven
    The Pulmonary Center Boston University School of Medicine Boston, MA USA
    Organogenesis 9:194-8. 2013
  2. pmc An NT4/TrkB-dependent increase in innervation links early-life allergen exposure to persistent airway hyperreactivity
    Linh Aven
    1The Pulmonary Center, Department of Medicine, Boston University School of Medicine, 72 East Concord Street, Boston, MA 02118, USA
    FASEB J 28:897-907. 2014
  3. pmc A new approach for the study of lung smooth muscle phenotypes and its application in a murine model of allergic airway inflammation
    Jesus Paez-Cortez
    The Pulmonary Center, Boston University School of Medicine, Boston, Massachusetts, United States of America
    PLoS ONE 8:e74469. 2013
  4. pmc Derivation of lung mesenchymal lineages from the fetal mesothelium requires hedgehog signaling for mesothelial cell entry
    Radhika Dixit
    The Pulmonary Center, Department of Medicine, Boston University School of Medicine, 72 East Concord Street, Boston, MA 02118, USA
    Development 140:4398-406. 2013
  5. pmc Neural crest cell origin and signals for intrinsic neurogenesis in the mammalian respiratory tract
    Aliete Langsdorf
    Pulmonary Center, Department of Medicine, Boston University School of Medicine, MA 02118, USA
    Am J Respir Cell Mol Biol 44:293-301. 2011
  6. pmc Trinucleotide repeat containing 6a (Tnrc6a)-mediated microRNA function is required for development of yolk sac endoderm
    Zhihua Jiang
    Pulmonary Center, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    J Biol Chem 287:5979-87. 2012
  7. pmc A Shh/miR-206/BDNF cascade coordinates innervation and formation of airway smooth muscle
    Kelsi Radzikinas
    The Pulmonary Center, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    J Neurosci 31:15407-15. 2011
  8. pmc Molecular determinants of lung development
    Edward E Morrisey
    Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA
    Ann Am Thorac Soc 10:S12-6. 2013

Collaborators

Detail Information

Publications8

  1. pmc Mechanisms of respiratory innervation during embryonic development
    Linh Aven
    The Pulmonary Center Boston University School of Medicine Boston, MA USA
    Organogenesis 9:194-8. 2013
    ..In this review, we focus on signaling mechanisms that underlie innervation of the embryonic respiratory tract. ..
  2. pmc An NT4/TrkB-dependent increase in innervation links early-life allergen exposure to persistent airway hyperreactivity
    Linh Aven
    1The Pulmonary Center, Department of Medicine, Boston University School of Medicine, 72 East Concord Street, Boston, MA 02118, USA
    FASEB J 28:897-907. 2014
    ....
  3. pmc A new approach for the study of lung smooth muscle phenotypes and its application in a murine model of allergic airway inflammation
    Jesus Paez-Cortez
    The Pulmonary Center, Boston University School of Medicine, Boston, Massachusetts, United States of America
    PLoS ONE 8:e74469. 2013
    ..Ultimately, this tool will provide direction and guidance for the logical development of new markers and approaches for studying human lung smooth muscle. ..
  4. pmc Derivation of lung mesenchymal lineages from the fetal mesothelium requires hedgehog signaling for mesothelial cell entry
    Radhika Dixit
    The Pulmonary Center, Department of Medicine, Boston University School of Medicine, 72 East Concord Street, Boston, MA 02118, USA
    Development 140:4398-406. 2013
    ..These findings further support a paradigm wherein the mesothelium is a source of progenitors for mesenchymal lineages during organogenesis and indicate that signals controlling mesothelial cell entry are organ specific. ..
  5. pmc Neural crest cell origin and signals for intrinsic neurogenesis in the mammalian respiratory tract
    Aliete Langsdorf
    Pulmonary Center, Department of Medicine, Boston University School of Medicine, MA 02118, USA
    Am J Respir Cell Mol Biol 44:293-301. 2011
    ....
  6. pmc Trinucleotide repeat containing 6a (Tnrc6a)-mediated microRNA function is required for development of yolk sac endoderm
    Zhihua Jiang
    Pulmonary Center, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    J Biol Chem 287:5979-87. 2012
    ....
  7. pmc A Shh/miR-206/BDNF cascade coordinates innervation and formation of airway smooth muscle
    Kelsi Radzikinas
    The Pulmonary Center, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    J Neurosci 31:15407-15. 2011
    ..Together, our work uncovers a functional cascade that involves Shh, miR-206 and BDNF to coordinate ASM formation and innervation...
  8. pmc Molecular determinants of lung development
    Edward E Morrisey
    Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA
    Ann Am Thorac Soc 10:S12-6. 2013
    ..This manuscript describes the summary of the discussion along with general recommendations to overcome the gaps in knowledge in lung developmental biology...

Research Grants1

  1. Identification of Sulfs as therapeutic targets for the treatment of age-impaired
    Xingbin Ai; Fiscal Year: 2010
    ..Our findings may open new venues for prevention and therapy of aging-related impairment of skeletal muscle regeneration. ..