Boston University

..The purpose of the present analyses was to update the findings by cancer stage and to evaluate the joint use of statins and NSAIDs...

..To provide an evidence-based review of plausible causal pathways that could best explain well-established associations between limited health literacy and health outcomes...

..We conducted a genome-wide association study (GWAS) in the community-based Framingham Heart Study...

..Biogeochemical models must be reformulated to allow C transfers below ground that result in additional N uptake under elevated CO(2)...

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..The purpose of this article is to present the reader with a brief description of those characteristics of piezoelectric materials that directly influence imaging...

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..b) Workers' losses may be substantially reduced by policies that encourage employers to rehire people recovering from or disabled by workplace injuries and illnesses...

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..Results predict that the single most important factor causing this airway hyperreactivity is amplified maximum ASM tension and not a thickening of the airway wall per se...

..Our method is extendable to N-component clusters, and therefore serves as a general tool for high order protein function annotation...

..This paper estimates the impact of antiretroviral therapy (ART) on days harvesting tea per month for tea-estate workers in Kenya. Such information is needed to assess the potential economic benefits of providing treatment to working adults...

..We assessed the relation of SDB to LV morphology and systolic function in a community-based sample of middle-aged and older adults...

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..Furthermore, resonant X-ray emission at the carbon K-edge was used to measure the density of states for individual C sites in the molecule...

..This exploratory study examined pre-event drinking, or pregaming, by US college students...

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..Studies on the anti-tumor effects of a more potent analog of Paricalcitol are underway. 1alpha,25(OH)(2)D(3) and its analogs are potentially attractive novel therapies for pancreatic cancer...

..01, ns). Findings document substantial HIV/STD risk and prevalence among Russian narcology patients, but no link between binge drinking and unprotected sex in this population, possibly due to very low rates of condom use generally...

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..Instead, they should rigorously explore possible cause-and-effect relations between vitamin D(3) status and specific diseases while advocating the safest possible means of ensuring vitamin D(3) sufficiency...

..Our goal was to determine whether adverse childhood experiences predicted the age at which drinking was initiated and drinking motives in a representative sample of current or former drinkers in the United States...

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..These findings suggest that the all-Exon array is a more robust platform for measuring airway epithelial gene expression and can serve as an effective tool for exploring host response to and damage from cigarette smoke...

..This makes CaspaTag ideal for showing an overall pattern or level of cell death over a period of time, while caspase antibodies provide a snapshot of cell death at a specific time point...

..These results suggest that the regulation of mitochondrial function via the mitochondrial PKA and CREB pathways may underlie some of the salutary effects of DFO in neurons...

..Here we review the history and properties of human mesotrypsin, and discuss its function in the digestive degradation of dietary trypsin inhibitors and possible pathophysiological role in pancreatitis...

..To our knowledge, no single investigation concerning the long-term effects of overweight status on the risk for hypertension, hypercholesterolemia, diabetes mellitus, and cardiovascular sequelae has been reported...

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..Eleven patients met the criteria for a substituted specimen, with elevated specific gravity of > or = 1.020 and creatinine concentration of < or = 5 mg/dL; however, these patients were seriously ill or terminally ill...

..The disparity between the laboratory and clinical studies suggests that there may be differences between species with regard to the role of endothelin in erectile function...

..Therefore, the effect of longitudinal coupling cannot be neglected in the region of the peak of the traveling wave...

..These studies clarify the mechanisms of viral neutralization by collectins and might be useful in engineering collectins for enhanced antiviral activity...

..The mechanism of exercise remains unclear and merits future studies to better define a concise, clear exercise protocol that may have the potential for a public health intervention...

..Finally, the software offers an output format that allows the convenient visualization of data points using animated, three-dimensional graphs...

..Moreover, the EGF-receptor-dependent pathway may be subject to negative-feedback regulation via m3 receptor-coupled activation of PKC...

..Findings are discussed with regard to sample characteristics and similarity to other reports on predictors of course and of treatment outcome...

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..Investigation of the pattern of this variation in hypertensive sibling pairs suggests that the alpha2B receptor locus does not contribute substantially to genetic susceptibility for essential hypertension...

..This study assessed chronic child illness among recipients of Temporary Assistance for Needy Families (TANF) benefits and poor families not receiving benefits...

..Sensitivity and specificity for the least random classification procedure were 0.87 and 0.67, respectively. The results suggest that computer-assisted screening methods are a promising means of triaging patients...

..The latter innervate peripheral autonomic organs, whose activity is markedly increased during emotional arousal...

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..The purpose of this study was to examine qualities of caregiver-child interactions during daily activities of healthy children born full-term and of children born prematurely and very low birth weight with and without white matter disorder...

..We used data collected from a case-control study of HFM to estimate risk in relation to parental military service and, in particular, Gulf War service...

..I examined the association between urban sprawl and the risk for being overweight or obese among US adults...

..The two-pathway switch seems to provide a mechanism for the "catch bond" response observed recently with PSGL-1-P-selectin bonds subjected to small-constant forces...

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..Evidence suggests that alcoholics exhibit particular deficits in brain systems involving the prefrontal cortex, but few studies have directly compared patients with and without Korsakoff's syndrome on measures of prefrontal integrity...

..Included is a discussion of staffing and the training methods developed. The article concludes with lessons learned that may be of interest to other researchers conducting similar health outcomes studies...

..Transient complexes with large interface areas undergo substantial conformational change and are beyond the reach of current docking methods. The docking of such complexes might therefore require fundamentally new approaches...

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..Further study of the signaling of regulation of the cardiac extracellular matrix may lead to new approaches for the treatment of myocardial remodeling and failure...

..This reorientation is crucial for reasserting the ethos of clinical medicine, whose fundamental mandate remains the care of others...

..This study suggests that the anti-inflammatory mechanism of salicylate involves inhibition of NOS 2 transcription and shows that the effect is independent of NF-kappaB activation...

..The main hypothesis is that perceived emotional control will mediate treatment outcome and generality of effectiveness independent of the specific treatment condition. ..

..This study addresses an important public health issue by assessing an intervention that may lead to a more efficient and effective application of empirically based psychosocial interventions for the treatment of SAD. ..

..This study addresses an important public health issue by assessing an intervention that may lead to a more efficient and effective application of empirically based psychosocial interventions for the treatment of SAD. ..

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..Results from this study should provide important new insights into the photoproduction of toxisterols and suprasterols in human skin and provide new information about their potential biologic functions in the skin. ..

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..Shortcomings in tobacco control curriculum in medical schools is a well-recognized deficit. Since 1996, Boston University has developed a curriculum with 10-15 new hours of tobacco control curriculum for students graduating in the ..

..This project amplifies work underway in the Boston University (BU) Center for Measuring Outcomes funded by the National Institute of Disability and Rehabilitation ..

..Many rehabilitation settings may also find this measure helpful in meeting accreditation and institutional requirements for standardizing outcome monitoring in groups of children. ..

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..Research could guide combined use of drugs influencing GABAb and ACh receptors. ..

..I-m), and testing time course of mGluR modulation of transmission in s. I-m. Understanding these mechanisms may assist in development of pharmacological treatments for Alzheimer's disease. ..

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..I-m), and testing time course of mGluR modulation of transmission in s. I-m. Understanding these mechanisms may assist in development of pharmacological treatments for Alzheimer's disease. ..

..If the AHEAD approach improves outcomes as hypothesized, the study results will support the use of a novel health services delivery strategy to better care for patients with alcoholism. ..

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