Demin Wang


Affiliation: Blood Research Institute
Country: USA


  1. Chen Y, Zheng Y, You X, Yu M, Fu G, Su X, et al. Kras Is Critical for B Cell Lymphopoiesis. J Immunol. 2016;196:1678-85 pubmed publisher
    ..Thus, Kras is the unique Ras family member that plays a critical role in early B cell development and late B cell maturation through controlling the Raf-1/MEK/ERK pathway. ..
  2. Yu M, Chen Y, Zeng H, Zheng Y, Fu G, Zhu W, et al. PLCĪ³-dependent mTOR signalling controls IL-7-mediated early B cell development. Nat Commun. 2017;8:1457 pubmed publisher
    ..Thus, IL-7 receptor controls early B lymphopoiesis through activation of mTOR via PLCĪ³/DAG/PKC signaling, not via Akt/Rheb signaling. ..