Michael W Mosesson

Summary

Affiliation: Blood Research Institute
Country: USA

Publications

  1. ncbi request reprint Update on antithrombin I (fibrin)
    Michael W Mosesson
    The Blood Research Institute, BloodCenter of Wisconsin, PO Box 2178, Milwaukee, WI 53201 2178, USA
    Thromb Haemost 98:105-8. 2007
  2. doi request reprint Thrombosis risk modification in transgenic mice containing the human fibrinogen thrombin-binding gamma' chain sequence
    M W Mosesson
    Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI 53201 2178, USA
    J Thromb Haemost 7:102-10. 2009
  3. doi request reprint Evidence that alpha2-antiplasmin becomes covalently ligated to plasma fibrinogen in the circulation: a new role for plasma factor XIII in fibrinolysis regulation
    M W Mosesson
    Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI, USA
    J Thromb Haemost 6:1565-70. 2008
  4. ncbi request reprint Cause-effect relation between hyperfibrinogenemia and vascular disease
    Bryce Kerlin
    Blood Research Institute, Blood Center of SE Wisconsin, Milwaukee 53226, USA
    Blood 103:1728-34. 2004
  5. pmc Studies on the basis for the properties of fibrin produced from fibrinogen-containing gamma' chains
    Kevin R Siebenlist
    Department of Biomedical Sciences, College of Health Sciences, Marquette University, Schroeder Health Complex, 426, PO Box 1881, Milwaukee, WI 53233 1881, USA
    Blood 106:2730-6. 2005
  6. pmc Caveolin-1-dependent apoptosis induced by fibrin degradation products
    Yi He Guo
    Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI 53226 3548, USA
    Blood 113:4431-9. 2009
  7. ncbi request reprint Antithrombin I. Inhibition of thrombin generation in plasma by fibrin formation
    Michael W Mosesson
    The Blood Research Institute of the Blood Center of Southeastern Wisconsin, PO Box 2178, Milwaukee, WI 53201 2178, USA
    Thromb Haemost 89:9-12. 2003
  8. ncbi request reprint John Douglass Ferry (1912-2002)--a memorial tribute
    Michael W Mosesson
    The Blood Center of Southeastern Wisconsin, The Blood Research Institute, Milwaukee, WI 53201 2178, USA
    Biophys Chem 112:91-3. 2004
  9. ncbi request reprint Regulation of transglutaminase activity in articular chondrocytes through thrombin receptor-mediated factor XIII synthesis
    Ann K Rosenthal
    Division of Rheumatology, Medical College of Wisconsin, Milwaukee, WI, USA
    Thromb Haemost 91:558-68. 2004
  10. ncbi request reprint John Ferry and the mechanical properties of cross-linked fibrin
    Michael W Mosesson
    The Blood Research Institute of the Blood Center of Southeastern Wisconsin, PO Box 2178, Milwaukee, WI 53201 2178, USA
    Biophys Chem 112:215-8. 2004

Collaborators

Detail Information

Publications22

  1. ncbi request reprint Update on antithrombin I (fibrin)
    Michael W Mosesson
    The Blood Research Institute, BloodCenter of Wisconsin, PO Box 2178, Milwaukee, WI 53201 2178, USA
    Thromb Haemost 98:105-8. 2007
    ..g. fibrinogen Naples 1), or a reduced plasma gamma' chain content (reduced antithrombin I activity), predispose to intravascular thrombosis...
  2. doi request reprint Thrombosis risk modification in transgenic mice containing the human fibrinogen thrombin-binding gamma' chain sequence
    M W Mosesson
    Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI 53201 2178, USA
    J Thromb Haemost 7:102-10. 2009
    ..This feature prompted us to produce a 'gain-of-function' transgenic mouse in which the wild-type (WT) C-terminal mu-gamma' chain fibrinogen sequence had been replaced with the C-terminal thrombin-binding human gamma' sequence...
  3. doi request reprint Evidence that alpha2-antiplasmin becomes covalently ligated to plasma fibrinogen in the circulation: a new role for plasma factor XIII in fibrinolysis regulation
    M W Mosesson
    Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI, USA
    J Thromb Haemost 6:1565-70. 2008
    ..We propose that alpha2AP becomes ligated to fibrinogen while in the circulation through the action of FXIII, and that its immediate presence in plasma fibrinogen contributes to regulation of in vivo fibrinolysis...
  4. ncbi request reprint Cause-effect relation between hyperfibrinogenemia and vascular disease
    Bryce Kerlin
    Blood Research Institute, Blood Center of SE Wisconsin, Milwaukee 53226, USA
    Blood 103:1728-34. 2004
    ....
  5. pmc Studies on the basis for the properties of fibrin produced from fibrinogen-containing gamma' chains
    Kevin R Siebenlist
    Department of Biomedical Sciences, College of Health Sciences, Marquette University, Schroeder Health Complex, 426, PO Box 1881, Milwaukee, WI 53233 1881, USA
    Blood 106:2730-6. 2005
    ..Fourth, fibrinolysis of fibrin 2 was delayed compared with fibrin 1. Altogether, differences between the structure and function of fibrins 1 and 2 are attributable to the effects of thrombin binding to gamma' chains...
  6. pmc Caveolin-1-dependent apoptosis induced by fibrin degradation products
    Yi He Guo
    Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI 53226 3548, USA
    Blood 113:4431-9. 2009
    ....
  7. ncbi request reprint Antithrombin I. Inhibition of thrombin generation in plasma by fibrin formation
    Michael W Mosesson
    The Blood Research Institute of the Blood Center of Southeastern Wisconsin, PO Box 2178, Milwaukee, WI 53201 2178, USA
    Thromb Haemost 89:9-12. 2003
    ..e., via gamma' chains) plays a dominant role in this process. AT-1 should be considered when assessing the pathogenesis of thromboembolic disease...
  8. ncbi request reprint John Douglass Ferry (1912-2002)--a memorial tribute
    Michael W Mosesson
    The Blood Center of Southeastern Wisconsin, The Blood Research Institute, Milwaukee, WI 53201 2178, USA
    Biophys Chem 112:91-3. 2004
  9. ncbi request reprint Regulation of transglutaminase activity in articular chondrocytes through thrombin receptor-mediated factor XIII synthesis
    Ann K Rosenthal
    Division of Rheumatology, Medical College of Wisconsin, Milwaukee, WI, USA
    Thromb Haemost 91:558-68. 2004
    ..Such increases in potential transglutaminase activity may facilitate pathological matrix calcification in degenerative arthritis...
  10. ncbi request reprint John Ferry and the mechanical properties of cross-linked fibrin
    Michael W Mosesson
    The Blood Research Institute of the Blood Center of Southeastern Wisconsin, PO Box 2178, Milwaukee, WI 53201 2178, USA
    Biophys Chem 112:215-8. 2004
    ..This article describes the role John Ferry played in relating the location of cross-linked gamma-chains in fibrin fibrils to the mechanical properties of fibrin clot...
  11. pmc Crystal structure of the complex between thrombin and the central "E" region of fibrin
    Igor Pechik
    Jerome H Holland Laboratory for the Biomedical Sciences, American Red Cross, 15601 Crabbs Branch Way, Rockville, MD 20855, USA
    Proc Natl Acad Sci U S A 101:2718-23. 2004
    ..Thus, despite the highly charged nature of the interacting surfaces, hydrophobic contacts make a substantial contribution to the interaction...
  12. ncbi request reprint Congenital hypodysfibrinogenaemia (Fibrinogen Des Moines) due to a gamma320Asp deletion at the Ca2+ binding site
    Stephen O Brennan
    Molecular Pathology Laboratory, Christchurch School of Medicine, Christchurch, New Zealand
    Thromb Haemost 98:467-9. 2007
  13. ncbi request reprint Fibrinogen Columbus: a novel gamma Gly200Val mutation causing hypofibrinogenemia in a family with associated thrombophilia
    Ryan L Davis
    Haematologica 92:1151-2. 2007
    ..2-5 Here we report the identification of a novel point mutation gammaG200V (fibrinogen Columbus) causing hypofibrinogenemia and co-segregating with three genetic thrombophilia risk factors...
  14. ncbi request reprint The effect of a thrombin exosite 2-binding DNA aptamer (HD-22) on non-catalytic thrombin-enhanced fibrin polymerization
    Michael W Mosesson
    Thromb Haemost 97:327-8. 2007
  15. ncbi request reprint Crystal structure of thrombin in complex with fibrinogen gamma' peptide
    Agustin O Pineda
    Biophys Chem 125:556-9. 2007
    ..These findings are consistent with functional data and broaden our understanding of how thrombin interacts with fibrinogen at the molecular level...
  16. ncbi request reprint Dysfibrinogenemia (fibrinogen Wilmington) due to a novel Aalpha chain truncation causing decreased plasma expression and impaired fibrin polymerisation
    Stephen O Brennan
    Canterbury Health Laboratories, Christchurch Hospital, Cnr Hagley Ave and Tuam St, Christchurch, New Zealand
    Thromb Haemost 96:88-9. 2006
  17. ncbi request reprint Hypofibrinogenaemia resulting from novel single nucleotide deletion at codon Bbeta58 (3404del A) associated with thrombotic stroke in infancy
    Stephen O Brennan
    Molecular Pathology Laboratory, Canterbury Health Laboratories, P O Box 151, Christchurch, New Zealand
    Thromb Haemost 95:738-9. 2006
  18. pmc Structural basis for sequential cleavage of fibrinopeptides upon fibrin assembly
    Igor Pechik
    Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute and National Institute of Standards and Technology, Rockville, Maryland 20850, USA
    Biochemistry 45:3588-97. 2006
    ..These findings provide a coherent rationale for the preferential removal of fpA from fibrinogen at the first stage of fibrin assembly and the accelerated cleavage of fpB from protofibrils and/or fibrils at the second stage...
  19. ncbi request reprint Fibrinogen Saint-Germain II: hypofibrinogenemia due to heterozygous gamma N345S mutation
    Emmanuelle de Raucourt
    Laboratoire d Hematologie, CHI Poissy St Germain en Laye, St Germain en Laye, France
    Thromb Haemost 94:965-8. 2005
    ..The hypofibrinogenemia may be contributory to the thrombophilic manifestations...
  20. ncbi request reprint John D. Ferry's patents
    John L Schrag
    Department of Chemistry, University of Wisconsin, 1101 University Avenue, Madison, WI 53706, USA
    Biophys Chem 112:95-101. 2004
  21. ncbi request reprint Theme issue: fibrinogen and fibrin--structure, function, interactions and clinical applications
    Carl Erik Dempfle
    Thromb Haemost 89:599-600. 2003
  22. ncbi request reprint Fibrinogen assembly and crosslinking on a fibrin fragment E template
    Michael W Mosesson
    The Blood Research Institute of the Blood Center of Southeastern Wisconsin, Milwaukee 53201 2178, USA
    Thromb Haemost 87:651-8. 2002
    ....