Brian R Curtis

Summary

Affiliation: Blood Research Institute
Country: USA

Publications

  1. ncbi request reprint Genotyping for human platelet alloantigen polymorphisms: applications in the diagnosis of alloimmune platelet disorders
    Brian R Curtis
    BloodCenter of Wisconsin, Platelet and Neutrophil Immunology Laboratory, Milwaukee, Wisconsin 53201 2178, USA
    Semin Thromb Hemost 34:539-48. 2008
  2. ncbi request reprint Future preventive and therapeutic targets for transfusion-related acute lung injury
    Brian R Curtis
    Platelet and Neutrophil Immunology Lab, BloodCenter of Wisconsin, Milwaukee, WI 53201 2178, USA
    Curr Pharm Des 18:3285-92. 2012
  3. pmc Hypersensitivity reaction and acute immune-mediated thrombocytopenia from oxaliplatin: two case reports and a review of the literature
    Marnelli A Bautista
    Department of Pathology and Laboratory Medicine, Loma Linda University Medical Center, Loma Linda, CA 92354, USA
    J Hematol Oncol 3:12. 2010
  4. ncbi request reprint Immune-mediated thrombocytopenia resulting from sensitivity to oxaliplatin
    Brian R Curtis
    Platelet and Neutrophil Immunology Laboratory, BloodCenter of Wisconsin, Milwaukee, 53201 2178, USA
    Am J Hematol 81:193-8. 2006
  5. pmc Neonatal alloimmune thrombocytopenia associated with maternal-fetal incompatibility for blood group B
    Brian R Curtis
    Platelet and Neutrophil Immunology Laboratory, BloodCenter of Wisconsin, Milwaukee, WI 53201 2178, USA
    Transfusion 48:358-64. 2008
  6. pmc The neutrophil alloantigen HNA-3a (5b) is located on choline transporter-like protein 2 and appears to be encoded by an R>Q154 amino acid substitution
    Brian R Curtis
    Platelet and Neutrophil Immunology Laboratory, BloodCenter of Wisconsin, PO Box 2178, Milwaukee, WI 53201 2178, USA
    Blood 115:2073-6. 2010
  7. pmc HNA-3a-specific antibodies recognize choline transporter-like protein-2 peptides containing arginine, but not glutamine at Position 154
    Brian R Curtis
    Platelet and Neutrophil Immunology Lab, BloodCenter of Wisconsin, Milwaukee, Wisconsin 53201 2178, USA
    Transfusion 51:2168-74. 2011
  8. pmc Full-length recombinant choline transporter-like protein 2 containing arginine 154 reconstitutes the epitope recognized by HNA-3a antibodies
    Adam J Kanack
    Blood Research Institute, BloodCenter of Wisconsin, 8727 Watertown Plank Road, Milwaukee, WI 53226 3548, USA
    Transfusion 52:1112-6. 2012
  9. ncbi request reprint Thrombocytopenia resulting from sensitivity to GPIIb-IIIa inhibitors
    Richard H Aster
    Medical College of Wisconsin, Blood Research Institute, The Blood Center of Southeastern Wisconsin, Milwaukee, Wisconsin, USA
    Semin Thromb Hemost 30:569-77. 2004
  10. ncbi request reprint Neonatal alloimmune neutropenia attributed to maternal immunoglobulin G antibodies against the neutrophil alloantigen HNA-1c (SH): a report of five cases
    Brian R Curtis
    Platelet and Neutrophil Immunology Laboratory, The Blood Center of Southeastern Wisconsin, Milwaukee, Wisconsin 53233, USA
    Transfusion 45:1308-13. 2005

Collaborators

Detail Information

Publications29

  1. ncbi request reprint Genotyping for human platelet alloantigen polymorphisms: applications in the diagnosis of alloimmune platelet disorders
    Brian R Curtis
    BloodCenter of Wisconsin, Platelet and Neutrophil Immunology Laboratory, Milwaukee, Wisconsin 53201 2178, USA
    Semin Thromb Hemost 34:539-48. 2008
    ..Platelet genotyping may also someday prove important as an aid in determining the relative risk of patients for various thrombotic disorders...
  2. ncbi request reprint Future preventive and therapeutic targets for transfusion-related acute lung injury
    Brian R Curtis
    Platelet and Neutrophil Immunology Lab, BloodCenter of Wisconsin, Milwaukee, WI 53201 2178, USA
    Curr Pharm Des 18:3285-92. 2012
    ..Insights already gained from studies of ALI-ARDS treatments will be summarized and discussed as possible therapeutic targets for treatment of patients experiencing TRALI...
  3. pmc Hypersensitivity reaction and acute immune-mediated thrombocytopenia from oxaliplatin: two case reports and a review of the literature
    Marnelli A Bautista
    Department of Pathology and Laboratory Medicine, Loma Linda University Medical Center, Loma Linda, CA 92354, USA
    J Hematol Oncol 3:12. 2010
    ..The incidence of hypersensitivity reaction in patients receiving oxaliplatin is approximately 15%, with severe reaction (grade 3 and 4) occurring in 2% of patients...
  4. ncbi request reprint Immune-mediated thrombocytopenia resulting from sensitivity to oxaliplatin
    Brian R Curtis
    Platelet and Neutrophil Immunology Laboratory, BloodCenter of Wisconsin, Milwaukee, 53201 2178, USA
    Am J Hematol 81:193-8. 2006
    ....
  5. pmc Neonatal alloimmune thrombocytopenia associated with maternal-fetal incompatibility for blood group B
    Brian R Curtis
    Platelet and Neutrophil Immunology Laboratory, BloodCenter of Wisconsin, Milwaukee, WI 53201 2178, USA
    Transfusion 48:358-64. 2008
    ..The implications of this trait for transfusion medicine are undefined...
  6. pmc The neutrophil alloantigen HNA-3a (5b) is located on choline transporter-like protein 2 and appears to be encoded by an R>Q154 amino acid substitution
    Brian R Curtis
    Platelet and Neutrophil Immunology Laboratory, BloodCenter of Wisconsin, PO Box 2178, Milwaukee, WI 53201 2178, USA
    Blood 115:2073-6. 2010
    ....
  7. pmc HNA-3a-specific antibodies recognize choline transporter-like protein-2 peptides containing arginine, but not glutamine at Position 154
    Brian R Curtis
    Platelet and Neutrophil Immunology Lab, BloodCenter of Wisconsin, Milwaukee, Wisconsin 53201 2178, USA
    Transfusion 51:2168-74. 2011
    ..However, it has not been shown by direct experiment that R154 is essential for the HNA-3a epitope...
  8. pmc Full-length recombinant choline transporter-like protein 2 containing arginine 154 reconstitutes the epitope recognized by HNA-3a antibodies
    Adam J Kanack
    Blood Research Institute, BloodCenter of Wisconsin, 8727 Watertown Plank Road, Milwaukee, WI 53226 3548, USA
    Transfusion 52:1112-6. 2012
    ..CTL2 peptides containing R154 are recognized by only half of HNA-3a antibodies studied to date. Constructs that react with all HNA-3a antibodies are needed to fully define the HNA-3a epitope...
  9. ncbi request reprint Thrombocytopenia resulting from sensitivity to GPIIb-IIIa inhibitors
    Richard H Aster
    Medical College of Wisconsin, Blood Research Institute, The Blood Center of Southeastern Wisconsin, Milwaukee, Wisconsin, USA
    Semin Thromb Hemost 30:569-77. 2004
    ..Additional studies are needed to more fully define the characteristics of these antibodies and to identify risk factors that predispose patients to this complication...
  10. ncbi request reprint Neonatal alloimmune neutropenia attributed to maternal immunoglobulin G antibodies against the neutrophil alloantigen HNA-1c (SH): a report of five cases
    Brian R Curtis
    Platelet and Neutrophil Immunology Laboratory, The Blood Center of Southeastern Wisconsin, Milwaukee, Wisconsin 53233, USA
    Transfusion 45:1308-13. 2005
    ..In this report, we describe five cases of NAN, in which only anti-HNA-1c was detected in maternal serum...
  11. pmc Determination of neutrophil antigen HNA-3a and HNA-3b genotype frequencies in six racial groups by high-throughput 5' exonuclease assay
    Krista L Bowens
    Platelet and Neutrophil Immunology Laboratory, BloodCenter of Wisconsin, Milwaukee, Wisconsin 53201 2178, USA
    Transfusion 52:2368-74. 2012
    ..However, knowledge of HNA-3 allele frequencies outside Caucasian populations is limited. We developed a high-throughput genotyping assay and determined the HNA-3a/3b genotype frequencies in six different racial and ethnic groups...
  12. ncbi request reprint Vancomycin-induced immune thrombocytopenia
    Annette Von Drygalski
    Department of Medicine, Medical College of Wisconsin, Milwaukee, USA
    N Engl J Med 356:904-10. 2007
    ..We conducted a study to determine whether thrombocytopenia is caused by vancomycin-dependent antibodies in patients being treated with vancomycin...
  13. ncbi request reprint Acute thrombocytopenia after treatment with tirofiban or eptifibatide is associated with antibodies specific for ligand-occupied GPIIb/IIIa
    Daniel W Bougie
    Blood Research Institute, The Blood Center of Southeastern Wisconsin, PO Box 2178, Milwaukee, WI 53201 2178, USA
    Blood 100:2071-6. 2002
    ..These antibodies may be human analogs of mouse monoclonal antibodies that recognize ligand-induced binding sites (LIBS) induced in the GPIIb/IIIa heterodimer when it reacts with a ligand-mimetic drug...
  14. pmc Prevalence and clinical significance of low-avidity HPA-1a antibodies in women exposed to HPA-1a during pregnancy
    Julie A Peterson
    Blood Research Institute and Platelet and Neutrophil Immunology Laboratory, BloodCenter of Wisconsin, Milwaukee, WI 53226 3548, USA
    Transfusion 53:1309-18. 2013
    ..We performed studies to further define the incidence and clinical significance of this type of antibody...
  15. ncbi request reprint Mechanisms of transfusion-related acute lung injury (TRALI): anti-leukocyte antibodies
    Brian R Curtis
    Platelet and Neutrophil Immunology Laboratory, BloodCenter of Wisconsin, Milwaukee, WI, USA
    Crit Care Med 34:S118-23. 2006
    ..Genotyping for class I and II HLA and for a limited number of neutrophil antigens may also be helpful in establishing antibody-antigen concordance...
  16. pmc Protamine-induced immune thrombocytopenia
    Atul Singla
    Cleveland Clinic Foundation, Cleveland, Ohio Platelet and Neutrophil Immunology Laboratory, Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, Wisconsin Division of Hematology, Duke University Medical Center, Durham, North Carolina Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin
    Transfusion 53:2158-63. 2013
    ..We encountered a patient who experienced profound thrombocytopenia and bleeding shortly after administration of protamine and performed studies to characterize the responsible mechanism...
  17. ncbi request reprint Acute thrombocytopenia in patients treated with the oral glycoprotein IIb/IIIa inhibitors xemilofiban and orbofiban: evidence for an immune etiology
    Jacqueline A Brassard
    Blood Research Institute, Blood Center of Wisconsin, Milwaukee, WI 53201 2178, USA
    Thromb Haemost 88:892-7. 2002
    ..Measurement of drug-dependent antibodies may be helpful in determining the basis for acute thrombocytopenia in fiban-treated patients and possibly for identification of patients at risk to develop thrombocytopenia...
  18. ncbi request reprint Neonatal neutropenia and bacterial sepsis associated with placental transfer of maternal neutrophil-specific autoantibodies
    Anne Davoren
    Blood Center of Southeastern Wisconsin, Inc, Milwaukee, Wisconsin, USA
    Transfusion 44:1041-6. 2004
    ..The firstborn developed Citrobacter meningitis and was permanently disabled. The second was success-fully managed with pre- and postnatal injections of recombinant human granulocyte colony-stimulating factor (rHuG-CSF)...
  19. ncbi request reprint Human platelet antigen-specific alloantibodies implicated in 1162 cases of neonatal alloimmune thrombocytopenia
    Anne Davoren
    Blood Center of Southeastern Wisconsin, Milwaukee, Wisconsin 53201 2178, USA
    Transfusion 44:1220-5. 2004
    ..As a national reference center for NATP investigations, our experience with this entity over a 12-year period was reviewed...
  20. ncbi request reprint Fetal and neonatal alloimmune thrombocytopenia in pregnancies involving in vitro fertilization: a report of four cases
    Brian R Curtis
    The Blood Center of Southeastern Wisconsin, Milwaukee, Wis, USA
    Am J Obstet Gynecol 192:543-7. 2005
    ..We report four cases of neonatal alloimmune thrombocytopenia (NATP) in pregnancies achieved with in vitro fertilization...
  21. pmc Low-frequency human platelet antigens as triggers for neonatal alloimmune thrombocytopenia
    Julie A Peterson
    Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, Wisconsin
    Transfusion 54:1286-93. 2014
    ..We performed studies to define more fully how often these antigens trigger maternal immunization leading to NAIT...
  22. pmc Neonatal alloimmune thrombocytopenia: pathogenesis, diagnosis and management
    Julie A Peterson
    Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI 53226 3548, US
    Br J Haematol 161:3-14. 2013
    ....
  23. pmc New platelet glycoprotein polymorphisms causing maternal immunization and neonatal alloimmune thrombocytopenia
    Julie A Peterson
    Blood Research Institute and Platelet and Neutrophil Immunology Laboratory, BloodCenter of Wisconsin, 8727 Watertown Plank Road, Milwaukee, WI 53226 3548, USA
    Transfusion 52:1117-24. 2012
    ..Maternal immunization against low-frequency, platelet (PLT)-specific antigens is being recognized with increasing frequency as a cause of neonatal alloimmune thrombocytopenia (NAIT)...
  24. ncbi request reprint Isoimmunization against CD36 (glycoprotein IV): description of four cases of neonatal isoimmune thrombocytopenia and brief review of the literature
    Brian R Curtis
    Platelet and Neutrophil Immunology Lab, Blood Center of Southeastern Wisconsin, Milwaukee 53233, USA
    Transfusion 42:1173-9. 2002
    ..A subset of these individuals is at risk for immunization against CD36, but the magnitude of this problem and its significance in transfusion medicine have not yet been clarified...
  25. ncbi request reprint Thrombocytopenia after second exposure to abciximab is caused by antibodies that recognize abciximab-coated platelets
    Brian R Curtis
    Platelet Neutrophil Immunology Laboratory, The Blood Center of Southeastern Wisconsin, PO Box 2178, Milwaukee, WI 53201 2178, USA
    Blood 99:2054-9. 2002
    ..It may be possible to identify patients at risk for developing thrombocytopenia if given abciximab by screening for antibodies that recognize 7E3-coated platelets...
  26. ncbi request reprint Anti-GPVI-associated ITP: an acquired platelet disorder caused by autoantibody-mediated clearance of the GPVI/FcRgamma-chain complex from the human platelet surface
    Brian Boylan
    Blood Research Institute, The Blood Center of Southeastern Wisconsin, PO Box 2178, 638 N 18th St, Milwaukee, WI 53201, USA
    Blood 104:1350-5. 2004
    ....
  27. pmc Maternal alloimmunization against the rare platelet-specific antigen HPA-9b (Max a) is an important cause of neonatal alloimmune thrombocytopenia
    Julie A Peterson
    The Blood Research Institute, The BloodCenter of Wisconsin, 8727 Watertown Plank Road, Wauwatosa, WI 53226, USA
    Transfusion 45:1487-95. 2005
    ..This study investigated whether this can be explained in part by maternal immunization against the "rare" alloantigen HPA-9b (Max(a)), implicated previously only in a single NATP case...
  28. ncbi request reprint Expression of ABH antigens on platelets
    Brian R Curtis
    Blood 107:842; author reply 842-3. 2006
  29. pmc Donor antibodies to HNA-3a implicated in TRALI reactions prime neutrophils and cause PMN-mediated damage to human pulmonary microvascular endothelial cells in a two-event in vitro model
    Christopher C Silliman
    Bonfils Blood Center and the Department of Pediatrics, University of Colorado at Denver School of Medicine 80230, USA
    Blood 109:1752-5. 2007
    ..Thus, antibodies to HNA-3a primed PMNs and caused PMN-mediated HMVEC cytotoxicity in a two-event model identical to biologic response modifiers implicated in TRALI...