Carmen Bergom

Summary

Affiliation: Blood Research Institute
Country: USA

Publications

  1. ncbi request reprint The cell-adhesion and signaling molecule PECAM-1 is a molecular mediator of resistance to genotoxic chemotherapy
    Carmen Bergom
    Blood Research Institute, Blood Center of Wisconsin, and Department of Cell Biology, Medical College of Wisconsin, Milwaukee, Wisconsin 53201, USA
    Cancer Biol Ther 5:1699-707. 2006
  2. ncbi request reprint Mechanisms of PECAM-1-mediated cytoprotection and implications for cancer cell survival
    Carmen Bergom
    Blood Research Institute, The Blood Center of Southeastern Wisconsin, Milwaukee, Milwaukee, WI, USA
    Leuk Lymphoma 46:1409-21. 2005
  3. pmc An alternatively spliced isoform of PECAM-1 is expressed at high levels in human and murine tissues, and suggests a novel role for the C-terminus of PECAM-1 in cytoprotective signaling
    Carmen Bergom
    Blood Research Institute, BloodCenter of Wisconsin, 8727 Watertown Plank Road, Milwaukee, WI 53201, USA
    J Cell Sci 121:1235-42. 2008
  4. ncbi request reprint Endothelial cell PECAM-1 confers protection against endotoxic shock
    Matthias Maas
    Blood Research Institute, Blood Center of Southeastern Wisconsin, PO Box 2178, 638 N 18th St, Milwaukee, WI 53201, USA
    Am J Physiol Heart Circ Physiol 288:H159-64. 2005
  5. ncbi request reprint PECAM-1 functions as a specific and potent inhibitor of mitochondrial-dependent apoptosis
    Cunji Gao
    Laboratories of PECAM 1 Research and Cell Biology, Blood Research Institute, The Blood Center of Southeastern Wisconsin, PO Box 2178, 638 N 18th St, Milwaukee, WI 53201, USA
    Blood 102:169-79. 2003

Collaborators

  • Peter J Newman
  • Reema Goel
  • Matthias Maas
  • Debra K Newman
  • Cunji Gao
  • David L Mattson
  • Michelle Stapleton
  • Shigemi Matsuyama
  • Melpo Christofidou-Solomidou
  • Weiyong Sun
  • Motoshi Sawada
  • Steven M Albelda

Detail Information

Publications5

  1. ncbi request reprint The cell-adhesion and signaling molecule PECAM-1 is a molecular mediator of resistance to genotoxic chemotherapy
    Carmen Bergom
    Blood Research Institute, Blood Center of Wisconsin, and Department of Cell Biology, Medical College of Wisconsin, Milwaukee, Wisconsin 53201, USA
    Cancer Biol Ther 5:1699-707. 2006
    ..In addition, reducing PECAM-1 levels in the tumor endothelium may aid in low-dose, anti-angiogenic therapy...
  2. ncbi request reprint Mechanisms of PECAM-1-mediated cytoprotection and implications for cancer cell survival
    Carmen Bergom
    Blood Research Institute, The Blood Center of Southeastern Wisconsin, Milwaukee, Milwaukee, WI, USA
    Leuk Lymphoma 46:1409-21. 2005
    ....
  3. pmc An alternatively spliced isoform of PECAM-1 is expressed at high levels in human and murine tissues, and suggests a novel role for the C-terminus of PECAM-1 in cytoprotective signaling
    Carmen Bergom
    Blood Research Institute, BloodCenter of Wisconsin, 8727 Watertown Plank Road, Milwaukee, WI 53201, USA
    J Cell Sci 121:1235-42. 2008
    ..These studies suggest a novel role for the PECAM-1 C-terminus in cytoprotective signaling and highlight a need for further characterization of expression of PECAM-1 isoforms in normal and malignant tissues...
  4. ncbi request reprint Endothelial cell PECAM-1 confers protection against endotoxic shock
    Matthias Maas
    Blood Research Institute, Blood Center of Southeastern Wisconsin, PO Box 2178, 638 N 18th St, Milwaukee, WI 53201, USA
    Am J Physiol Heart Circ Physiol 288:H159-64. 2005
    ..The diverse functional roles played by PECAM-1 in thrombosis, inflammation, apoptosis, and the immune response may make this molecule an attractive target for the development of novel therapeutics to manage and treat endotoxic shock...
  5. ncbi request reprint PECAM-1 functions as a specific and potent inhibitor of mitochondrial-dependent apoptosis
    Cunji Gao
    Laboratories of PECAM 1 Research and Cell Biology, Blood Research Institute, The Blood Center of Southeastern Wisconsin, PO Box 2178, 638 N 18th St, Milwaukee, WI 53201, USA
    Blood 102:169-79. 2003
    ....