Affiliation: Blanchette Rockefeller Neurosciences Institute
Zhao W, Ravindranath L, Mohamed A, Zohar O, Chen G, Lyketsos C, et al. MAP kinase signaling cascade dysfunction specific to Alzheimer's disease in fibroblasts. Neurobiol Dis. 2002;11:166-83 pubmed
..Moreover, detection of AD-specific differences in MAP kinase in peripheral tissues may provide an efficient means for early diagnosis of AD as well as help us to identify therapeutic targets for drug discovery. ..
Zhao W, Chen G, Chen H, Pascale A, Ravindranath L, Quon M, et al. Secretion of Annexin II via activation of insulin receptor and insulin-like growth factor receptor. J Biol Chem. 2003;278:4205-15 pubmed
..These results suggest that the insulin receptor and its signaling pathways may participate in molecular mechanisms mediating annexin II secretion. ..