E L Berg

Summary

Affiliation: BioSeek Inc
Country: USA

Publications

  1. ncbi request reprint Approaches to the analysis of cell signaling networks and their application in drug discovery
    Ellen L Berg
    BioSeek Inc, Burlingame, CA 94010, USA
    Curr Opin Drug Discov Devel 8:107-14. 2005
  2. doi request reprint Chemical target and pathway toxicity mechanisms defined in primary human cell systems
    Ellen L Berg
    BioSeek, Inc, 310 Utah 100, South San Francisco, CA 94080, USA
    J Pharmacol Toxicol Methods 61:3-15. 2010
  3. doi request reprint Systems biology in drug discovery and development
    Ellen L Berg
    BioSeek, a division of DiscoveRx, 310 Utah Avenue, Suite 100, South San Francisco, CA 94080, USA Electronic address
    Drug Discov Today 19:113-25. 2014
  4. ncbi request reprint Characterization of compound mechanisms and secondary activities by BioMAP analysis
    Ellen L Berg
    BioSeek, Inc, 863 C Mitten Rd, Burlingame, CA 94010, USA
    J Pharmacol Toxicol Methods 53:67-74. 2006
  5. ncbi request reprint Biological complexity and drug discovery: a practical systems biology approach
    E L Berg
    BioSeek Inc, Burlingame, CA 94010, USA
    Syst Biol (Stevenage) 152:201-6. 2005
  6. ncbi request reprint An integrative biology approach for analysis of drug action in models of human vascular inflammation
    Eric J Kunkel
    BioSeek, Inc, Burlingame, California 94010, USA
    FASEB J 18:1279-81. 2004
  7. pmc Method for analyzing signaling networks in complex cellular systems
    Ivan Plavec
    BioSeek, Inc, Burlingame, CA 94010, USA
    Proc Natl Acad Sci U S A 101:1223-8. 2004
  8. ncbi request reprint Systems biology in drug discovery
    Eugene C Butcher
    Laboratory of Immunology and Vascular Biology, Department of Pathology, Stanford University School of Medicine, Stanford, California 94305 5324, USA
    Nat Biotechnol 22:1253-9. 2004
  9. ncbi request reprint Rapid structure-activity and selectivity analysis of kinase inhibitors by BioMAP analysis in complex human primary cell-based models
    Eric J Kunkel
    BioSeek, Inc, Bingame, CA, USA
    Assay Drug Dev Technol 2:431-41. 2004

Research Grants

Collaborators

Detail Information

Publications9

  1. ncbi request reprint Approaches to the analysis of cell signaling networks and their application in drug discovery
    Ellen L Berg
    BioSeek Inc, Burlingame, CA 94010, USA
    Curr Opin Drug Discov Devel 8:107-14. 2005
    ..In this review, experimental and computational methods for modeling complex CSNs and the applications of these approaches to pharmaceutical drug discovery are discussed...
  2. doi request reprint Chemical target and pathway toxicity mechanisms defined in primary human cell systems
    Ellen L Berg
    BioSeek, Inc, 310 Utah 100, South San Francisco, CA 94080, USA
    J Pharmacol Toxicol Methods 61:3-15. 2010
    ..Approaches that detect and discriminate a broad range of mechanisms in testing formats that are predictive and yet cost-effective are needed...
  3. doi request reprint Systems biology in drug discovery and development
    Ellen L Berg
    BioSeek, a division of DiscoveRx, 310 Utah Avenue, Suite 100, South San Francisco, CA 94080, USA Electronic address
    Drug Discov Today 19:113-25. 2014
    ....
  4. ncbi request reprint Characterization of compound mechanisms and secondary activities by BioMAP analysis
    Ellen L Berg
    BioSeek, Inc, 863 C Mitten Rd, Burlingame, CA 94010, USA
    J Pharmacol Toxicol Methods 53:67-74. 2006
    ....
  5. ncbi request reprint Biological complexity and drug discovery: a practical systems biology approach
    E L Berg
    BioSeek Inc, Burlingame, CA 94010, USA
    Syst Biol (Stevenage) 152:201-6. 2005
    ..Compound profiling in these systems has revealed that a surprisingly large number of biological mechanisms can be detected and distinguished. Features of these assays relevant to the behaviour of complex systems are described...
  6. ncbi request reprint An integrative biology approach for analysis of drug action in models of human vascular inflammation
    Eric J Kunkel
    BioSeek, Inc, Burlingame, California 94010, USA
    FASEB J 18:1279-81. 2004
    ..BioMAP profiling can allow integration of meaningful human biology into drug development programs...
  7. pmc Method for analyzing signaling networks in complex cellular systems
    Ivan Plavec
    BioSeek, Inc, Burlingame, CA 94010, USA
    Proc Natl Acad Sci U S A 101:1223-8. 2004
    ....
  8. ncbi request reprint Systems biology in drug discovery
    Eugene C Butcher
    Laboratory of Immunology and Vascular Biology, Department of Pathology, Stanford University School of Medicine, Stanford, California 94305 5324, USA
    Nat Biotechnol 22:1253-9. 2004
    ..These systems biology approaches promise to improve decision making in pharmaceutical development...
  9. ncbi request reprint Rapid structure-activity and selectivity analysis of kinase inhibitors by BioMAP analysis in complex human primary cell-based models
    Eric J Kunkel
    BioSeek, Inc, Bingame, CA, USA
    Assay Drug Dev Technol 2:431-41. 2004
    ..Integration of automated BioMAP analysis for prioritization of hits and for structure-activity relationship studies may improve and accelerate the design and selection of optimal therapeutic candidates...

Research Grants1