Aniela Jakubowski

Summary

Affiliation: Biogen Idec
Country: USA

Publications

  1. ncbi TWEAKing tissue remodeling by a multifunctional cytokine: role of TWEAK/Fn14 pathway in health and disease
    Linda C Burkly
    Department of Immunobiology, Biogen Idec, 12 Cambridge Center, Cambridge, MA 02142, USA
    Cytokine 40:1-16. 2007
  2. pmc TWEAK induces liver progenitor cell proliferation
    Aniela Jakubowski
    Department of Exploratory Science, Biogen Idec Inc, Cambridge, Massachusetts 02142, USA
    J Clin Invest 115:2330-40. 2005
  3. ncbi Dual role for TWEAK in angiogenic regulation
    Aniela Jakubowski
    Department of Exploratory Science, Biogen Inc, 12 Cambridge Center, Cambridge, Massachusetts 02142, USA
    J Cell Sci 115:267-74. 2002
  4. pmc The cytokine TWEAK modulates renal tubulointerstitial inflammation
    Ana Belen Sanz
    Unidad de Dialisis, Fundacion Jimenez Diaz, Avda Reyes Catolicos 2, 28040 Madrid, Spain
    J Am Soc Nephrol 19:695-703. 2008

Collaborators

Detail Information

Publications4

  1. ncbi TWEAKing tissue remodeling by a multifunctional cytokine: role of TWEAK/Fn14 pathway in health and disease
    Linda C Burkly
    Department of Immunobiology, Biogen Idec, 12 Cambridge Center, Cambridge, MA 02142, USA
    Cytokine 40:1-16. 2007
    ..In addition to a perspective of the biology, we discuss potential therapeutic strategies targeting this pathway for the treatment of tissue injury, chronic inflammatory diseases and cancer...
  2. pmc TWEAK induces liver progenitor cell proliferation
    Aniela Jakubowski
    Department of Exploratory Science, Biogen Idec Inc, Cambridge, Massachusetts 02142, USA
    J Clin Invest 115:2330-40. 2005
    ..We conclude that TWEAK has a selective mitogenic effect for liver oval cells that distinguishes it from other previously described growth factors...
  3. ncbi Dual role for TWEAK in angiogenic regulation
    Aniela Jakubowski
    Department of Exploratory Science, Biogen Inc, 12 Cambridge Center, Cambridge, Massachusetts 02142, USA
    J Cell Sci 115:267-74. 2002
    ..Thus, our observations suggest that TWEAK may differentially regulate microvascular growth, remodeling and/or maintenance in vivo, depending upon the angiogenic context...
  4. pmc The cytokine TWEAK modulates renal tubulointerstitial inflammation
    Ana Belen Sanz
    Unidad de Dialisis, Fundacion Jimenez Diaz, Avda Reyes Catolicos 2, 28040 Madrid, Spain
    J Am Soc Nephrol 19:695-703. 2008
    ..Moreover, blockade of TWEAK reduces tubular chemokine expression and macrophage infiltration, suggesting that TWEAK modulates acute kidney injury by regulating the inflammatory response...