Donald P Kotler

Summary

Affiliation: Beth Israel Medical Center
Country: USA

Publications

  1. doi request reprint Hepatitis C, human immunodeficiency virus and metabolic syndrome: interactions
    Donald P Kotler
    Division of Gastroenterology and Liver Disease, St Lukes Roosevelt Hospital Center, New York, NY 10025, USA
    Liver Int 29:38-46. 2009
  2. ncbi request reprint Toxic shock-like syndrome associated with staphylococcal enterocolitis in an HIV-infected man
    Donald P Kotler
    Division of Gastroenterology, Department of Medicine and Pathology, St Luke s Roosevelt Hospital Center, New York, NY 10025, USA
    Clin Infect Dis 44:e121-3. 2007
  3. ncbi request reprint Total body protein: a new cellular level mass and distribution prediction model
    ZiMian Wang
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, NY 10025, USA
    Am J Clin Nutr 78:979-84. 2003
  4. pmc Insulin resistance, hepatic lipid and adipose tissue distribution in HIV-infected men
    Qing He
    Division of Gastroenterology, Department of Medicine, St Luke s Roosevelt Hospital Center, Columbia University, New York, NY, USA
    Antivir Ther 13:423-8. 2008
  5. ncbi request reprint Validation of an elliptical anthropometric model to estimate visceral compartment area
    Qing He
    Division of Gastroenterology, St Luke s Roosevelt Hospital Center, College of Physicians and Surgeons, Columbia University, New York, New York 10025, USA
    Obes Res 12:250-7. 2004
  6. ncbi request reprint Recombinant human growth hormone to treat HIV-associated adipose redistribution syndrome: 12 week induction and 24-week maintenance therapy
    Carl Grunfeld
    University of California, San Francisco Veterans Affairs Medical Center, and Columbia St Luke s Roosevelt Hospital, New York, NY, USA
    J Acquir Immune Defic Syndr 45:286-97. 2007
  7. pmc Independent associations of insulin resistance with high whole-body intermuscular and low leg subcutaneous adipose tissue distribution in obese HIV-infected women
    Jeanine B Albu
    Endocrine, Diabetes and Nutrition Division, The New York Obesity Research Center, St Luke s Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York, NY 10025, USA
    Am J Clin Nutr 86:100-6. 2007
  8. ncbi request reprint Body composition and metabolic effects of a diet and exercise weight loss regimen on obese, HIV-infected women
    Ellen S Engelson
    Gastrointestinal Division, St Luke s Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York, NY 10025, USA
    Metabolism 55:1327-36. 2006
  9. ncbi request reprint Body cell mass: model development and validation at the cellular level of body composition
    ZiMian Wang
    Weight Control Unit, Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, 1090 Amsterdam Avenue, 14th Floor, New York, NY 10025, USA
    Am J Physiol Endocrinol Metab 286:E123-8. 2004
  10. ncbi request reprint Studies of adipose tissue metabolism in human immunodeficiency virus-associated lipodystrophy
    Donald P Kotler
    Division of Gastroenterology, Obesity Research Center, Department of Medicine, St Luke s Roosevelt Hospital Center, College of Physicians and Surgeons, Columbia University, New York, New York 10025, USA
    Clin Infect Dis 37:S47-51. 2003

Detail Information

Publications47

  1. doi request reprint Hepatitis C, human immunodeficiency virus and metabolic syndrome: interactions
    Donald P Kotler
    Division of Gastroenterology and Liver Disease, St Lukes Roosevelt Hospital Center, New York, NY 10025, USA
    Liver Int 29:38-46. 2009
    ..Consideration must be given to selection of appropriate treatment regimens and timing of therapy in co-infected patients to minimize metabolic derangements and, ultimately, reduce cardiovascular risk...
  2. ncbi request reprint Toxic shock-like syndrome associated with staphylococcal enterocolitis in an HIV-infected man
    Donald P Kotler
    Division of Gastroenterology, Department of Medicine and Pathology, St Luke s Roosevelt Hospital Center, New York, NY 10025, USA
    Clin Infect Dis 44:e121-3. 2007
    ..The isolate was methicillin susceptible and produced enterotoxins B and C. This is, to our knowledge, the first reported case of toxic shock syndrome to develop secondary to staphylococcal enterocolitis in an adult...
  3. ncbi request reprint Total body protein: a new cellular level mass and distribution prediction model
    ZiMian Wang
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, NY 10025, USA
    Am J Clin Nutr 78:979-84. 2003
    ....
  4. pmc Insulin resistance, hepatic lipid and adipose tissue distribution in HIV-infected men
    Qing He
    Division of Gastroenterology, Department of Medicine, St Luke s Roosevelt Hospital Center, Columbia University, New York, NY, USA
    Antivir Ther 13:423-8. 2008
    ..This study investigates the interrelationships among fat distribution, hepatic lipid content, and insulin resistance in HIV-infected men...
  5. ncbi request reprint Validation of an elliptical anthropometric model to estimate visceral compartment area
    Qing He
    Division of Gastroenterology, St Luke s Roosevelt Hospital Center, College of Physicians and Surgeons, Columbia University, New York, New York 10025, USA
    Obes Res 12:250-7. 2004
    ..However, the two-dimensional shape of the abdomen is rarely circular. This study validated an elliptical model of cross-sectional total abdominal area (TAA), subcutaneous adipose tissue (SAT) area, and VCA at the L(4)-L(5) level...
  6. ncbi request reprint Recombinant human growth hormone to treat HIV-associated adipose redistribution syndrome: 12 week induction and 24-week maintenance therapy
    Carl Grunfeld
    University of California, San Francisco Veterans Affairs Medical Center, and Columbia St Luke s Roosevelt Hospital, New York, NY, USA
    J Acquir Immune Defic Syndr 45:286-97. 2007
    ..HIV-associated adipose redistribution syndrome (HARS) is an HIV-associated disorder characterized by excess truncal fat, including visceral adipose tissue (VAT)...
  7. pmc Independent associations of insulin resistance with high whole-body intermuscular and low leg subcutaneous adipose tissue distribution in obese HIV-infected women
    Jeanine B Albu
    Endocrine, Diabetes and Nutrition Division, The New York Obesity Research Center, St Luke s Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York, NY 10025, USA
    Am J Clin Nutr 86:100-6. 2007
    ..Obesity and insulin resistance are growing problems in HIV-positive (HIV+) women receiving highly active antiretroviral therapy (HAART)...
  8. ncbi request reprint Body composition and metabolic effects of a diet and exercise weight loss regimen on obese, HIV-infected women
    Ellen S Engelson
    Gastrointestinal Division, St Luke s Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York, NY 10025, USA
    Metabolism 55:1327-36. 2006
    ....
  9. ncbi request reprint Body cell mass: model development and validation at the cellular level of body composition
    ZiMian Wang
    Weight Control Unit, Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, 1090 Amsterdam Avenue, 14th Floor, New York, NY 10025, USA
    Am J Physiol Endocrinol Metab 286:E123-8. 2004
    ..0083 x TBK) formulated on rough tissue composition estimates. The present analyses provide a physiologically based, improved, and validated TBK-BCM prediction formula that should prove useful in body composition and metabolism research...
  10. ncbi request reprint Studies of adipose tissue metabolism in human immunodeficiency virus-associated lipodystrophy
    Donald P Kotler
    Division of Gastroenterology, Obesity Research Center, Department of Medicine, St Luke s Roosevelt Hospital Center, College of Physicians and Surgeons, Columbia University, New York, New York 10025, USA
    Clin Infect Dis 37:S47-51. 2003
    ..Further studies are needed to dissect the factors that mediate lipoatrophy in HIV infection...
  11. ncbi request reprint Increased systemic and adipose tissue cytokines in patients with HIV-associated lipodystrophy
    Julia A Johnson
    Obesity Research Center, St Luke s Roosevelt Hospital Center, College of Physicians and Surgeons, Columbia University, New York, NY 10025, USA
    Am J Physiol Endocrinol Metab 286:E261-71. 2004
    ....
  12. ncbi request reprint Intermuscular adipose tissue-free skeletal muscle mass: estimation by dual-energy X-ray absorptiometry in adults
    Jaehee Kim
    Obesity Research Center, College of Physicians and Surgeons, Columbia University, New York, NY 10025, USA
    J Appl Physiol 97:655-60. 2004
    ..The DXA-based models are accurate for predicting IMAT-free SM in selected populations and thus provide a new opportunity for quantifying SM in physiological and epidemiological investigations...
  13. ncbi request reprint A comparison of abdominal subcutaneous adipose tissue pattern in obese and lean HIV-infected women
    Qing He
    Division of Gastroenterology, Department of Medicine, St Luke s Roosevelt Hospital Center, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    J Nutr 135:53-7. 2005
    ..In summary, obesity is associated with a preferential increase in PDSAT and greater loss in PDSAT after weight loss. This study defines distinct metabolism responses in fat subcompartments...
  14. ncbi request reprint Preferential loss of omental-mesenteric fat during growth hormone therapy of HIV-associated lipodystrophy
    Qing He
    Division of Gastroenterology, Obesity Research Center, St Luke s Roosevelt Hospital Center, New York, New York 10025, USA
    J Appl Physiol 94:2051-7. 2003
    ..37%, P < 0.001). There is preferential loss and regain of OMAT, compared with RPAT, in subjects with HIV-associated lipodystrophy undergoing growth hormone treatment...
  15. ncbi request reprint Detection of segmental internal fat by bioelectrical impedance analysis in a biological phantom
    Qing He
    Division of Gastroenterology, St Luke s Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, 1111 Amsterdam Avenue, New York, NY 10025, USA
    Nutrition 19:541-4. 2003
    ..The purpose of this study was to test the hypothesis that surface impedance, determined by bioimpedance analysis, might be used to predict regional internal fat content change in a phantom model...
  16. doi request reprint The prevalence and pathogenesis of diabetes mellitus in treated HIV-infection
    Il Joon Paik
    Department of Medicine, St Luke s Roosevelt Hospital Center, College of Physicians and Surgeons, Columbia University, NY, USA
    Best Pract Res Clin Endocrinol Metab 25:469-78. 2011
    ..This article reviews studies concerning the prevalence and incidence of diabetes mellitus and HIV, HIV-specific effects on diabetes mellitus complications, and HIV-specific diabetes mellitus treatment considerations...
  17. doi request reprint HIV and antiretroviral therapy: lipid abnormalities and associated cardiovascular risk in HIV-infected patients
    Donald P Kotler
    Division of Gastroenterology, Department of Medicine, St Luke s Roosevelt Hospital Center, College of Physicians and Surgeons, Columbia University, New York, NY 10025, USA
    J Acquir Immune Defic Syndr 49:S79-85. 2008
    ....
  18. ncbi request reprint Effects of growth hormone on abnormal visceral adipose tissue accumulation and dyslipidemia in HIV-infected patients
    Donald P Kotler
    Division of GI Immunology, St Luke s Roosevelt Hospital Center, New York, NY, USA
    J Acquir Immune Defic Syndr 35:239-52. 2004
    ..Some HIV-infected patients develop fat maldistribution with visceral adipose tissue (VAT) accumulation and metabolic abnormalities. No medical treatment is approved by the US Food and Drug Administration to reduce VAT...
  19. doi request reprint Staphylococcal enterocolitis: forgotten but not gone?
    Zheng Lin
    Division of Gastroenterology, Department of Medicine, St Luke s Roosevelt Hospital Center, New York, NY 10025, USA
    Dig Dis Sci 55:1200-7. 2010
    ..A predominance of gram-positive cocci in clusters on gram stain of stool or biopsy specimens and the isolation of S. aureus as the dominant or sole flora support the diagnosis...
  20. pmc Developing an objective evaluation method to estimate diabetes risk in community-based settings
    Sonjia Kenya
    St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, Columbia University Mailman School of Public Health, New York, New York, USA
    Diabetes Technol Ther 13:557-61. 2011
    ..To determine how exercise interventions affect diabetes risk in community and university-based settings, improved evaluation methods are warranted...
  21. ncbi request reprint Nonalcoholic fatty liver disease in severely obese subjects
    Pierre M Gholam
    Division of Gastroenterology, St Luke s Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York, New York, USA
    Am J Gastroenterol 102:399-408. 2007
    ..The exact prevalence of NASH in severe obesity is unknown. It is unclear whether differences in insulin sensitivity exist among subjects with NASH and simple fatty liver...
  22. ncbi request reprint Bone mineral content is lower in prepubertal HIV-infected children
    Stephen M Arpadi
    Comprehensive Care Center, St Luke s Roosevelt Hospital Center, 1111 Amsterdam Avenue, New York, NY 10025, U S A
    J Acquir Immune Defic Syndr 29:450-4. 2002
    ..TBBMC is decreased in HIV-infected children. As a result of compromised bone mineral accrual, HIV-infected children may be at increased risk for osteoporosis and related complications...
  23. pmc Recombinant human growth hormone and rosiglitazone for abdominal fat accumulation in HIV-infected patients with insulin resistance: a randomized, double-blind, placebo-controlled, factorial trial
    Marshall J Glesby
    Department of Medicine, Weill Cornell Medical College, New York, New York, USA
    PLoS ONE 8:e61160. 2013
    ..We aimed to determine if adding rosiglitazone to rhGH would abrogate the adverse effects of rhGH on insulin sensitivity (SI) and subcutaneous adipose tissue (SAT) volume...
  24. ncbi request reprint Multicomponent methods: evaluation of new and traditional soft tissue mineral models by in vivo neutron activation analysis
    ZiMian Wang
    Department of Medicine, Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University, College of Physicians and Surgeons, New York, NY, USA
    Am J Clin Nutr 76:968-74. 2002
    ..Practical and accurate methods for quantifying the soft tissue mineral component of multicomponent fat-estimation models are needed...
  25. ncbi request reprint HIV lipodystrophy etiology and pathogenesis. Body composition and metabolic alterations: etiology and pathogenesis
    Donald P Kotler
    Department of Medicine, Division of Gastroenterology, Columbia University College of Physicians and Surgeons, New York, USA
    AIDS Read 13:S5-9. 2003
    ..Recent studies suggest that immune dysregulation rather than HIV infection per se may be the predominant factor in the development of lipodystrophy...
  26. ncbi request reprint Hepatoportal sclerosis as a cause of noncirrhotic portal hypertension in patients with HIV
    Thomas D Schiano
    The Recanati Miller Transplantation Institute, and the Division of Liver Diseases, Department of Medicine, The Mount Sinai Medical Center, New York, New York 10029, USA
    Am J Gastroenterol 102:2536-40. 2007
    ..Nodular regenerative hyperplasia (NRH), another cause of noncirrhotic portal hypertension, has also been recently described in HIV patients initially diagnosed as having cryptogenic liver disease...
  27. ncbi request reprint Gastric toxoplasmosis as the presentation of acquired immunodeficiency syndrome
    Mihai Merzianu
    Department of Pathology, St Luke s Roosevelt Hospital Center, New York, NY, USA
    Arch Pathol Lab Med 129:e87-90. 2005
    ....
  28. ncbi request reprint Lymphogranuloma venereum in human immunodeficiency virus-infected individuals in New York City
    Allen Ahdoot
    Gastrointestinal Division, Department of Medicine, St Luke s Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York, NY 10025, USA
    J Clin Gastroenterol 40:385-90. 2006
    ..It is important for gastroenterologists to recognize that LGV may be reemerging as a relevant clinical entity, because of its similarity to inflammatory bowel diseases and its response to treatment with antibiotics...
  29. ncbi request reprint Human immunodeficiency virus and pregnancy
    Donald P Kotler
    Gastrointestinal Division, Department of Medicine, 1301 St Luke s Roosevelt Hospital Center, College of Physicians and Surgeons, Columbia University, 1111 Amsterdam Avenue, New York, NY 10025, USA
    Gastroenterol Clin North Am 32:437-48, ix. 2003
    ..The most important parameter to follow is the maternal plasma HIV-RNA level, and the most important treatment issue is to reduce this level because it is directly related to the risk of vertical transmission...
  30. ncbi request reprint Use of a Durnin-Womersley formula to estimate change in subcutaneous fat content in HIV-infected subjects
    Shireen Andrade
    Gastrointestinal Division, the Weight Control Unit, The Department of Medicine, St Luke s Roosevelt Hospital Center, Columbia University of Physicians and Surgeons, New York, USA
    Am J Clin Nutr 75:587-92. 2002
    ..HIV-infected individuals may develop malnutrition or lipodystrophy, leading to losses of subcutaneous adipose tissue (SAT)...
  31. ncbi request reprint Body-size dependence of resting energy expenditure can be attributed to nonenergetic homogeneity of fat-free mass
    Steven B Heymsfield
    New York Obesity Research Center, St Luke s Roosevelt Hospital, New York, NY 10025, USA
    Am J Physiol Endocrinol Metab 282:E132-8. 2002
    ..These observations have important implications for the interpretation of between-individual differences in REE expressed relative to metabolically active tissue mass...
  32. pmc Contribution of metabolic and anthropometric abnormalities to cardiovascular disease risk factors
    Carl Grunfeld
    Circulation 118:e20-8. 2008
  33. ncbi request reprint Management of metabolic complications associated with antiretroviral therapy for HIV-1 infection: recommendations of an International AIDS Society-USA panel
    Morris Schambelan
    University of California San Francisco, San Francisco General Hospital, San Francisco, California, USA
    J Acquir Immune Defic Syndr 31:257-75. 2002
    ..These recommendations were developed to guide physicians actively involved in HIV care in the management of metabolic complications that occur primarily within the context of potent antiretroviral therapy...
  34. ncbi request reprint Effect of recombinant human growth hormone in the treatment of visceral fat accumulation in HIV infection
    Ellen S Engelson
    Gastrointestinal Division, Obesity Research Center, New York 10025, USA
    J Acquir Immune Defic Syndr 30:379-91. 2002
    ..However, frequent adverse effects warrant controlled studies and careful patient monitoring, especially regarding glucose tolerance...
  35. ncbi request reprint Clinical evaluation and management of metabolic and morphologic abnormalities associated with human immunodeficiency virus
    Christine A Wanke
    Tufts University School of Medicine, Boston, MA 02111, USA
    Clin Infect Dis 34:248-59. 2002
    ..We also suggest treatments and strategies to manage metabolic and morphologic changes in patients with HIV...
  36. ncbi request reprint Body mass index and waist circumference independently contribute to the prediction of nonabdominal, abdominal subcutaneous, and visceral fat
    Ian Janssen
    School of Physical and Health Education, Queen s University, Kingston, Ontario, Canada
    Am J Clin Nutr 75:683-8. 2002
    ....
  37. ncbi request reprint Effect of recombinant human growth hormone on exercise capacity in patients with HIV-associated wasting on HAART
    William J Evans
    Donald W Reynolds Institute on Aging, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
    AIDS Read 15:301-3, 306-8, 310, 314. 2005
    ..85 kJ (P < .0001). These improvements suggest that rhGH treatment may enable patients with wasting to perform activities of daily living that would be exhausting without rhGH treatment...
  38. ncbi request reprint Growth hormone improves lean body mass, physical performance, and quality of life in subjects with HIV-associated weight loss or wasting on highly active antiretroviral therapy
    Graeme J Moyle
    HIV Research and HIV GU Medicine Department, Chelsea and Westminster Hospital, London, UK
    J Acquir Immune Defic Syndr 35:367-75. 2004
    ..In conclusion, over the 12-week course of therapy, rhGH, 0.1 mg/kg DD, was superior to placebo in improving physical function, body weight, body composition, and QoL and was superior to AD dosing in restoring LBM...
  39. pmc State of the science conference: Initiative to decrease cardiovascular risk and increase quality of care for patients living with HIV/AIDS: executive summary
    Steven K Grinspoon
    Circulation 118:198-210. 2008
  40. ncbi request reprint Insulin resistance, glucose intolerance and diabetes mellitus in HIV-infected patients
    Diana Florescu
    Immunocompromised Host Infectious Diseases Program, Department of Medicine, University of Nebraska Medical Center, Omaha, NE, USA
    Antivir Ther 12:149-62. 2007
    ..This article reviews the latest knowledge regarding the epidemiology, pathogenesis, prevention and treatment of insulin resistance, glucose intolerance and diabetes mellitus in HIV-infected individuals...
  41. pmc Association of antiretroviral therapy with fibrinogen levels in HIV-infection
    Erin Madden
    Northern California Institute for Research and Education, San Francisco, USA
    AIDS 22:707-15. 2008
    ..HIV infection is associated with an increased risk of coronary artery disease, but the contribution of inflammation versus antiretroviral drugs is not well understood. Fibrinogen is an inflammatory factor associated with atherosclerosis...
  42. ncbi request reprint HIV infection and the gastrointestinal tract
    Donald P Kotler
    AIDS 19:107-17. 2005
  43. pmc Relationship of fat distribution with adipokines in human immunodeficiency virus infection
    Lisa A Kosmiski
    University of Colorado at Denver and Health Sciences Center, Denver, Colorado 80217, USA
    J Clin Endocrinol Metab 93:216-24. 2008
    ....
  44. ncbi request reprint Treating morphologic and metabolic complications in HIV-infected patients on antiretroviral therapy. A consensus statement of an advisory committee of the International Association of Physicians in AIDS Care
    Carl J Fichtenbaum
    IAPAC Mon 11:38-46. 2005
    ..Scientific and clinical research, and other data in published literature and abstracts from scientific conferences were considered by strength of evidence. This document represents the consensus agreement of the Advisory Committee...
  45. ncbi request reprint Oxandrolone in the treatment of HIV-associated weight loss in men: a randomized, double-blind, placebo-controlled study
    Carl Grunfeld
    University of California San Francisco, and Department of Veterans Affairs Medical Center, 4150 Clement Street, San Francisco, CA 94121, USA
    J Acquir Immune Defic Syndr 41:304-14. 2006
    ..To evaluate the efficacy and safety of oxandrolone in promoting body weight and body cell mass (BCM) gain in HIV-associated weight loss...
  46. ncbi request reprint Effects of growth hormone on visceral adipose tissue and dyslipidemia in HIV, an erratum
    Donald P Kotler
    J Acquir Immune Defic Syndr 43:378-80. 2006
  47. pmc Regional adipose tissue and elevations in serum aminotransferases in HIV-infected individuals
    Phyllis C Tien
    Department of Medicine, University of California, San Francisco, CA 94121, USA
    J Acquir Immune Defic Syndr 48:169-76. 2008
    ..Obesity is associated with hepatic steatosis, and ALT is a marker of steatosis in the general population...