K L Becker

Summary

Country: USA

Publications

  1. ncbi Clinical review 167: Procalcitonin and the calcitonin gene family of peptides in inflammation, infection, and sepsis: a journey from calcitonin back to its precursors
    K L Becker
    Veterans Affairs Medical Center and George Washington University, Washington, D.C. 20422, USA
    J Clin Endocrinol Metab 89:1512-25. 2004
  2. ncbi Immunoneutralization of procalcitonin as therapy of sepsis
    K L Becker
    George Washington University and Veterans Administration Medical Center, 50 Irving Street NW, Washington, DC 20422, USA
    J Endotoxin Res 9:367-74. 2003
  3. ncbi Late immunoneutralization of procalcitonin arrests the progression of lethal porcine sepsis
    J M Martinez
    Department of Surgery, George Washington University, Washington, DC, USA
    Surg Infect (Larchmt) 2:193-202; discussion 202-3. 2001
  4. ncbi Serum calcitonin precursors in sepsis and systemic inflammation
    K T Whang
    Georgetown University, Washington, D C 20422, USA
    J Clin Endocrinol Metab 83:3296-301. 1998
  5. ncbi Salivary procalcitonin and periodontitis in diabetes
    C W Bassim
    Veterans Affairs Medical Center, Washington, DC, USA
    J Dent Res 87:630-4. 2008
  6. ncbi Effects of anti-inflammatory agents on serum levels of calcitonin precursors during human experimental endotoxemia
    H L Preas
    Critical Care Medicine Department, Warren G. Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland, USA
    J Infect Dis 184:373-6. 2001
  7. ncbi Calcitonin gene-related peptide expression in sepsis: postulation of microbial infection-specific response elements within the calcitonin I gene promoter
    V S Domenech
    Department of Research Medicine, University Hospitals, Basel, Switzerland
    J Investig Med 49:514-21. 2001
  8. ncbi Calcitonin precursor levels in human medullary thyroid carcinoma
    H Bihan
    Avicenne Hospital, University of Paris XIII, , Bobigny, France
    Thyroid 13:819-22. 2003
  9. ncbi Calcitonin precursors: early markers of gut barrier dysfunction in patients with acute pancreatitis
    B J Ammori
    Division of Surgery at the University of Leeds, The General Infirmary, Leeds, UK
    Pancreas 27:239-43. 2003
  10. ncbi Calcitonin precursors in the prediction of severity of acute pancreatitis on the day of admission
    B J Ammori
    Division of Surgery, University of Leeds and Centre for Digestive Diseases, The General Infirmary, Leeds, UK
    Br J Surg 90:197-204. 2003

Collaborators

Detail Information

Publications13

  1. ncbi Clinical review 167: Procalcitonin and the calcitonin gene family of peptides in inflammation, infection, and sepsis: a journey from calcitonin back to its precursors
    K L Becker
    Veterans Affairs Medical Center and George Washington University, Washington, D.C. 20422, USA
    J Clin Endocrinol Metab 89:1512-25. 2004
  2. ncbi Immunoneutralization of procalcitonin as therapy of sepsis
    K L Becker
    George Washington University and Veterans Administration Medical Center, 50 Irving Street NW, Washington, DC 20422, USA
    J Endotoxin Res 9:367-74. 2003
    ..In both late and early therapy, the only animals to survive at the predetermined time of euthanasia were those which had received immunoneutralization therapy...
  3. ncbi Late immunoneutralization of procalcitonin arrests the progression of lethal porcine sepsis
    J M Martinez
    Department of Surgery, George Washington University, Washington, DC, USA
    Surg Infect (Larchmt) 2:193-202; discussion 202-3. 2001
    ..We hypothesized that the sustained elevation of ProCT in the serum would allow for effective therapeutic immunoneutralization of this peptide late in the course of sepsis...
  4. ncbi Serum calcitonin precursors in sepsis and systemic inflammation
    K T Whang
    Georgetown University, Washington, D C 20422, USA
    J Clin Endocrinol Metab 83:3296-301. 1998
    ..It also provides data concerning the presence of severe infection and may prove to be clinically useful for proactive patient care...
  5. ncbi Salivary procalcitonin and periodontitis in diabetes
    C W Bassim
    Veterans Affairs Medical Center, Washington, DC, USA
    J Dent Res 87:630-4. 2008
    ..This study demonstrates, for the first time, the presence of procalcitonin (ProCT), an established serum marker of infection, in saliva...
  6. ncbi Effects of anti-inflammatory agents on serum levels of calcitonin precursors during human experimental endotoxemia
    H L Preas
    Critical Care Medicine Department, Warren G. Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland, USA
    J Infect Dis 184:373-6. 2001
    ..Of importance, this study reveals that anti-inflammatory agents may modulate the CTpr level, which is a potential toxic mediator of inflammation...
  7. ncbi Calcitonin gene-related peptide expression in sepsis: postulation of microbial infection-specific response elements within the calcitonin I gene promoter
    V S Domenech
    Department of Research Medicine, University Hospitals, Basel, Switzerland
    J Investig Med 49:514-21. 2001
    ..This new form of endocrine plasticity may be of importance in the response to systemic inflammation...
  8. ncbi Calcitonin precursor levels in human medullary thyroid carcinoma
    H Bihan
    Avicenne Hospital, University of Paris XIII, , Bobigny, France
    Thyroid 13:819-22. 2003
    ..CONCLUSION: This study demonstrates the universal presence of CTpr in the blood of patients with MTC. The measurement of these peptides may offer a new dimension to the clinical evaluation of this malignancy...
  9. ncbi Calcitonin precursors: early markers of gut barrier dysfunction in patients with acute pancreatitis
    B J Ammori
    Division of Surgery at the University of Leeds, The General Infirmary, Leeds, UK
    Pancreas 27:239-43. 2003
    ..The aim of this study is to evaluate the role of plasma CTpr as an early marker for gut barrier dysfunction in patients with acute pancreatitis...
  10. ncbi Calcitonin precursors in the prediction of severity of acute pancreatitis on the day of admission
    B J Ammori
    Division of Surgery, University of Leeds and Centre for Digestive Diseases, The General Infirmary, Leeds, UK
    Br J Surg 90:197-204. 2003
    ....
  11. ncbi A case of spurious hypercalcitoninemia: a cautionary tale on the use of plasma calcitonin assays in the screening of patients with thyroid nodules for neoplasia
    G I Uwaifo
    Developmental Endocrinology Branch, National Institutes of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
    J Endocrinol Invest 24:361-9. 2001
    ..Finally, the assay selected should detect only the mature CT molecule...
  12. ncbi Ubiquitous expression of the calcitonin-i gene in multiple tissues in response to sepsis
    B Muller
    Laboratory of Molecular Endocrinology, Massachusetts General Hospital, Howard Hughes Medical Institute, Harvard Medical School, Boston, Massachusetts 02114, USA
    J Clin Endocrinol Metab 86:396-404. 2001
    ..g. tumor necrosis factor-alpha and interleukin-6). Our findings, which describe a potentially new mechanism of host response to a microbial infection mediated by CTpr, introduce a new pathophysiological role for the CT-I gene...
  13. ncbi Serum procalcitonin as an index of inhalation injury in burns
    E S Nylen
    George Washington University, Washington D.C
    Horm Metab Res 24:439-43. 1992
    ..The measurement of serum procalcitonin levels would appear to be a useful prognostic indicator of the severity of inhalational injury occurring in burn patients...