Ronald J Pettis

Summary

Affiliation: BD Biosciences
Country: USA

Publications

  1. ncbi request reprint Microneedle delivery: clinical studies and emerging medical applications
    Ronald J Pettis
    BD Technologies, P O Box 12016, 21 Davis Drive, Research Triangle Park, NC 27709, USA
    Ther Deliv 3:357-71. 2012
  2. doi request reprint Microneedle-based intradermal versus subcutaneous administration of regular human insulin or insulin lispro: pharmacokinetics and postprandial glycemic excursions in patients with type 1 diabetes
    Ronald J Pettis
    BD Technologies, Research Triangle Park, North Carolina 27709, USA
    Diabetes Technol Ther 13:443-50. 2011
  3. pmc Pharmacokinetics and postprandial glycemic excursions following insulin lispro delivered by intradermal microneedle or subcutaneous infusion
    Elaine McVey
    BD Technologies, Research Triangle Park, North Carolina 27709, USA
    J Diabetes Sci Technol 6:743-54. 2012
  4. doi request reprint Microneedle-based intradermal delivery enables rapid lymphatic uptake and distribution of protein drugs
    Alfred J Harvey
    BD Technologies, 21 Davis Drive, Research Triangle Park, North Carolina 27709, USA
    Pharm Res 28:107-16. 2011
  5. doi request reprint Intradermal microneedle delivery of insulin lispro achieves faster insulin absorption and insulin action than subcutaneous injection
    Ronald J Pettis
    BD Technologies, Research Triangle Park, North Carolina 27709, USA
    Diabetes Technol Ther 13:435-42. 2011
  6. pmc Intrinsic fibrillation of fast-acting insulin analogs
    R Jeremy Woods
    BD Technologies, Durham, North Carolina 27709, USA
    J Diabetes Sci Technol 6:265-76. 2012
  7. ncbi request reprint Improved genetic immunization via micromechanical disruption of skin-barrier function and targeted epidermal delivery
    John A Mikszta
    BD Technologies, Research Triangle Park, North Carolina, USA
    Nat Med 8:415-9. 2002

Collaborators

Detail Information

Publications7

  1. ncbi request reprint Microneedle delivery: clinical studies and emerging medical applications
    Ronald J Pettis
    BD Technologies, P O Box 12016, 21 Davis Drive, Research Triangle Park, NC 27709, USA
    Ther Deliv 3:357-71. 2012
    ..This review summarizes the various aspects of microneedle clinical evaluation to date and identifies areas requiring further clinical evaluation...
  2. doi request reprint Microneedle-based intradermal versus subcutaneous administration of regular human insulin or insulin lispro: pharmacokinetics and postprandial glycemic excursions in patients with type 1 diabetes
    Ronald J Pettis
    BD Technologies, Research Triangle Park, North Carolina 27709, USA
    Diabetes Technol Ther 13:443-50. 2011
    ....
  3. pmc Pharmacokinetics and postprandial glycemic excursions following insulin lispro delivered by intradermal microneedle or subcutaneous infusion
    Elaine McVey
    BD Technologies, Research Triangle Park, North Carolina 27709, USA
    J Diabetes Sci Technol 6:743-54. 2012
    ..We compared the PK and pharmacodynamic (PD) effects of insulin lispro administered before two daily standardized solid mixed meals (breakfast and lunch), using microneedle-based ID or traditional subcutaneous (SC) delivery...
  4. doi request reprint Microneedle-based intradermal delivery enables rapid lymphatic uptake and distribution of protein drugs
    Alfred J Harvey
    BD Technologies, 21 Davis Drive, Research Triangle Park, North Carolina 27709, USA
    Pharm Res 28:107-16. 2011
    ..The purpose of this research was to examine the pharmacokinetics (PK) of drug uptake for microneedle-based intradermal (ID) delivery of several classes of protein drugs compared to standard subcutaneous (SC) administration...
  5. doi request reprint Intradermal microneedle delivery of insulin lispro achieves faster insulin absorption and insulin action than subcutaneous injection
    Ronald J Pettis
    BD Technologies, Research Triangle Park, North Carolina 27709, USA
    Diabetes Technol Ther 13:435-42. 2011
    ..This study compared insulin lispro (IL) pharmacokinetics (PK) and pharmacodynamics (PD) delivered via microneedle intradermal (ID) injection with subcutaneous (SC) injection under euglycemic glucose clamp conditions...
  6. pmc Intrinsic fibrillation of fast-acting insulin analogs
    R Jeremy Woods
    BD Technologies, Durham, North Carolina 27709, USA
    J Diabetes Sci Technol 6:265-76. 2012
    ....
  7. ncbi request reprint Improved genetic immunization via micromechanical disruption of skin-barrier function and targeted epidermal delivery
    John A Mikszta
    BD Technologies, Research Triangle Park, North Carolina, USA
    Nat Med 8:415-9. 2002
    ..Together, the results provide the first in vivo use of microfabricated devices to breach the skin barrier and deliver vaccines topically, suggesting significant clinical and practical advantages over existing technologies...