Research Topics
Species | M ZhangSummaryAffiliation: Baylor College of Medicine Country: USA Publications
| Collaborators
|
Detail Information
Publications
Haploinsufficiency of the maspin tumor suppressor gene leads to hyperplastic lesions in prostateLong jiang Shao
Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, USA
Cancer Res 68:5143-51. 2008..This is the first report that a partial loss of maspin caused an early developmental defect of the prostate and prostate hyperplastic lesions in mouse...
Maspin overexpression modulates tumor cell apoptosis through the regulation of Bcl-2 family proteinsWeiguo Zhang
Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA
BMC Cancer 5:50. 2005..However, the molecular mechanism underlying this inhibition has not been fully elucidated. In this report, we analyze the effect of maspin on tumor cell apoptosis under several stress conditions...
Maspin plays an important role in mammary gland developmentM Zhang
Department of Cell Biology, Baylor College of Medicine, Houston, Texas 77030, USA
Dev Biol 215:278-87. 1999..These findings demonstrate that maspin plays an important role in mammary development and that its effect is stage dependent...- Maspin is an angiogenesis inhibitorM Zhang
Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA
Nat Med 6:196-9. 2000.... - Multiple functions of maspin in tumor progression and mouse developmentMing Zhang
Baylor College of Medicine, Department of Molecular and Cellular Biology, Houston, TX 77030, USA
Front Biosci 9:2218-26. 2004..These data demonstrate that maspin not only plays a role in tumor progression and metastasis but also is a key regulatory molecule for normal mammary gland and embryonic development... - Blocking tumor growth, invasion, and metastasis by maspin in a syngeneic breast cancer modelH Y Shi
Baylor College of Medicine, Department of Molecular and Cellular Biology, Houston, Texas 77030, USA
Cancer Res 61:6945-51. 2001..Thus, maspin can block primary tumor growth as well as invasion and metastasis. These data support the concept that maspin has a strong protective role against tumor progression... - Modeling human breast cancer metastasis in mice: maspin as a paradigmH Y Shi
Baylor College of Medicine, Department of Molecular and Cellular Biology, Houston, Texas 77030, USA
Histol Histopathol 18:201-6. 2003..Elucidating the molecular mechanism of maspin action will shed light on our understanding of breast cancer invasion and metastasis... - Cardiolipin in energy transducing membranesE Mileykovskaya
Department of Biochemistry and Molecular Biology, University of Texas Houston, Medical School, Houston, TX 77030, USA
Biochemistry (Mosc) 70:154-8. 2005..The role of cardiolipin in higher order organization of components of the mitochondrial respiratory chain revealed by a combined molecular genetic and biochemical approach is described... - Fluorescent probes attached to Cys 35 or Cys 84 in cardiac troponin C are differentially sensitive to Ca(2+)-dependent events in vitro and in situJ A Putkey
Department of Biochemistry and Molecular Biology, University of Texas Medical School, Houston 77225, USA
Biochemistry 36:970-8. 1997.... - Lack of mitochondrial anionic phospholipids causes an inhibition of translation of protein components of the electron transport chain. A yeast genetic model system for the study of anionic phospholipid function in mitochondriaD B Ostrander
Department of Biochemistry and Molecular Biology, University of Texas Medical School, Houston, TX 77225, USA
J Biol Chem 276:25262-72. 2001..Thus, the molecular basis for the lack of mitochondrial function in pgs1Delta cells is the failure to translate gene products essential to the electron transport chain... - Maspin controls mammary tumor cell migration through inhibiting Rac1 and Cdc42, but not the RhoA GTPaseHeidi Y Shi
Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA
Cell Motil Cytoskeleton 64:338-46. 2007..In addition, the AP-1 transcription activity downstream of JNK kinase pathway was also reduced. Together, we have identified Rac1 and Cdc42 as the downstream targets that mediate the inhibition of mammary tumor cell migration by maspin... - Cluster models of dose-volume effectsHoward D Thames
Department of Biostatistics, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
Int J Radiat Oncol Biol Phys 59:1491-504. 2004..Describe cluster models, normal-tissue complication probability models in which both the number and the spatial location of radiation-sterilized functional subunits play a role in defining complication probability... - Maspin mediates increased tumor cell apoptosis upon induction of the mitochondrial permeability transitionKhatri Latha
Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA
Mol Cell Biol 25:1737-48. 2005..Our data indicate that maspin inhibits tumor progression through the mitochondrial apoptosis pathway. These findings will be useful for maspin-based therapeutic interventions against breast cancer... - Interferon-inducible protein IFIXalpha inhibits cell invasion by upregulating the metastasis suppressor maspinHirohito Yamaguchi
Department of Molecular and Cellular Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
Mol Carcinog 47:739-43. 2008..Together, these data provide novel insights into the tumor-suppressive function of IFIXalpha... - Signaling through 3',5'-cyclic adenosine monophosphate and phosphoinositide-3 kinase induces sodium/iodide symporter expression in breast cancerKatherine A B Knostman
Department of Veterinary Biosciences, The Ohio State University, Columbus, Ohio 43210, USA
J Clin Endocrinol Metab 89:5196-203. 2004..This study is the first to demonstrate that NIS expression is induced by cAMP and/or PI3K in breast cancer both in vivo and in vitro... - BMP-6 promotes E-cadherin expression through repressing deltaEF1 in breast cancer cellsShuang Yang
Medical College of Nankai University, Tianjin, China
BMC Cancer 7:211. 2007..Bone morphogenetic protein-6 (BMP-6) is critically involved in many developmental processes. Recent studies indicate that BMP-6 is closely related to tumor differentiation and metastasis... - Targeted expression of maspin in tumor vasculatures induces endothelial cell apoptosisZhigang Li
Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA
Oncogene 24:2008-19. 2005..These findings demonstrate that neovascular endothelial cells are highly sensitive to maspin level inside the cells. This property can be used for targeted therapy against tumor angiogenesis and metastasis... - Maspin is physically associated with [beta]1 integrin regulating cell adhesion in mammary epithelial cellsNathalie Cella
Baylor College of Medicine, Department of Molecular and Cellular Biology, ALKEK Bldg, Rm N630, One Baylor Plaza, Houston, Texas 77030, USA
FASEB J 20:1510-2. 2006..Collectively, these results suggest that maspin is part of the supramolecular structure of the adhesion plaque and it modulates cell adhesion via a beta1 integrin-dependent mechanism... - Nuclear cytokine-activated IKKalpha controls prostate cancer metastasis by repressing MaspinJun Li Luo
Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology and Cancer Center, School of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093 0723, USA
Nature 446:690-4. 2007..We propose that tumour-infiltrating RANKL-expressing cells lead to nuclear IKKalpha activation and inhibition of Maspin transcription, thereby promoting the metastatic phenotype... - Expression of endothelial nitric oxide synthase and vascular endothelial growth factor in association with neovascularization in human primary astrocytomaJian Wei Pan
Department of Neurosurgery, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China
J Zhejiang Univ Sci B 6:693-8. 2005..To investigate the relationship between the expression of endothelial nitric oxide synthase (eNOS), vascular endothelial growth factor (VEGF) and angiogenesis in primary astrocytoma... - Cluster model analysis of late rectal bleeding after IMRT of prostate cancer: a case-control studySusan L Tucker
Department of Biostatistics and Applied Mathematics, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
Int J Radiat Oncol Biol Phys 64:1255-64. 2006..The purpose of this study was to test the validity of a two-dimensional cluster model of late rectal toxicity based on maximum cluster size of damage to rectal surface... - Downregulation of survivin expression and elevation of caspase-3 activity involved in pitavastatin-induced HepG 2 cell apoptosisJuyong Wang
Tumor Research Institute, Shanghai Academy of Traditional Chinese Medicine, Shanghai 200032, PR China
Oncol Rep 18:383-7. 2007..These results suggest that pitavastatin at 10 microM induces apoptosis of HepG 2 cells, which is associated with the decreased expression of survivin mRNA and increased caspase-3 activity of HepG 2 cells... - Hypoxia effects: implications for maspin regulation of the uPA/uPAR complexJeremy S Schaefer
Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA
Cancer Biol Ther 4:1033-5. 2005.... - Hormonal defect in maspin heterozygous mice reveals a role of progesterone in pubertal ductal developmentHeidi Y Shi
Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA
Mol Endocrinol 18:2196-207. 2004..In PRKO mice, a compensatory mechanism occurs that rescues the ductal defect at a late stage of mammary development... - Tamoxifen induces the expression of maspin through estrogen receptor-alphaZesheng Liu
Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, ALKEK Bldg, N630 Houston, TX 77030, USA
Cancer Lett 209:55-65. 2004..This finding indicates that one of the pathways for cancer prevention and tumor inhibition by TAM is mediated through the activation of tumor suppressor gene maspin in breast cancer... - Maspin functions as tumor suppressor by increasing cell adhesion to extracellular matrix in prostate tumor cellsShaji Abraham
Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, USA
J Urol 169:1157-61. 2003.... - Toward re-expressing tumor suppresor gene maspin in breast cancerMing Zhang
Clin Breast Cancer 3:353-4. 2002 - Maspin expression in invasive breast cancer: association with other prognostic factorsSyed K Mohsin
Breast Center, Baylor College of Medicine, Houston, Texas 77030, USA
J Pathol 199:432-5. 2003..Additional studies are needed to evaluate further this expression profile of maspin in breast cancer... - Hypermethylation and histone deacetylation lead to silencing of the maspin gene in human breast cancerNicolai Maass
Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of Kiel, Michaelisstrasse 16, 24105 Kiel, Germany
Biochem Biophys Res Commun 297:125-8. 2002..The re-expression of maspin by pharmacological intervention potentially offers a promising new target as a therapeutic option in breast cancer... - Inhibition of breast tumor progression by systemic delivery of the maspin gene in a syngeneic tumor modelHeidi Y Shi
Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA
Mol Ther 5:755-61. 2002..Such inhibition is mediated by SERPINB5 transgene through increased apoptosis in SERPINB5-treated tumors. Thus, SERPINB5 can be used in gene therapy against breast tumor growth and metastasis... - Clinicopathological significance and molecular regulation of maspin expression in ductal adenocarcinoma of the pancreasNobuyuki Ohike
Department of Pathology, University of Kiel, Kiel, Germany
Cancer Lett 199:193-200. 2003.... - Tissue microarray analysis of maspin expression and its reverse correlation with mutant p53 in various tumorsWeiguo Zhang
Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA
Int J Oncol 20:1145-50. 2002..Our data indicate that maspin expression inversely correlates with mutant p53 level in majority of cancer, suggesting maspin is likely a p53 target gene in vivo... - Role of maspin in tumor metastasis and angiogenesisJeremy S Schaefer
Baylor College of Medicine, Department of Molecular and Cellular Biology, Houston, TX 77030, USA
Curr Mol Med 3:653-8. 2003..Efforts underway to understand the molecular mechanisms involved in the diverse functions influenced by maspin have yielded promising results and shed light on the cancer pathways... - Expression and regulation of tumor suppressor gene maspin in human bladder cancerShuji Sugimoto
Department of Urology, University of Kiel, Arnold Heller Strasse 7, Kiel 24105, Germany
Cancer Lett 203:209-15. 2004..Our results indicate that maspin may contribute to bladder cancer development and that DNA methylation and histone deacetylation may be important for regulating maspin gene activation in bladder cancer cells... - Maspin plays an essential role in early embryonic developmentFei Gao
Baylor College of Medicine, Department of Molecular and Cellular Biology, One Baylor Plaza, Houston, TX 77030, USA
Development 131:1479-89. 2004..We conclude that deletion of maspin affects VE function by reducing cell proliferation and adhesion, thereby controlling early embryonic development... - Valproic acid induces p21 and topoisomerase-II (alpha/beta) expression and synergistically enhances etoposide cytotoxicity in human glioblastoma cell linesChandra M Das
Department of Pediatrics, Unit 853, University of Texas, M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
J Neurooncol 85:159-70. 2007..In this study, we have examined the ability of the histone deacetylase inhibitor, valproic acid (VPA) to modulate gene expression and sensitize glioblastoma cell lines to the cytotoxic effects of etoposide in vitro... - Epigenetic regulation of bone morphogenetic protein-6 gene expression in breast cancer cellsMing Zhang
Laboratory of Molecular Medicines, Medical College, Nankai University, Tianjin 300071, China
J Steroid Biochem Mol Biol 105:91-7. 2007.... - The complementary neighborhood patterns and methylation-to-mutation likelihood structures of 15,110 single-nucleotide polymorphisms in the bovine genomeZhihua Jiang
Department of Animal Sciences, Washington State University, Pullman, Washington 99164 6351, USA
Genetics 180:639-47. 2008..In addition, conversion can occur at both CpG sites and non-CpG sites. Our study provides new insights into understanding molecular mechanisms of mutations and genome evolution... - Proteomics demonstration that normal breast epithelial cells can induce apoptosis of breast cancer cells through insulin-like growth factor-binding protein-3 and maspinRobert Alain Toillon
INSERM ERI 8 JE 2488 Signalisation des facteurs de croissance dans le cancer du sein Protéomique fonctionnelle, Universite des Sciences et Technologies de Lille, 59655 Villeneuve d Ascq, France
Mol Cell Proteomics 6:1239-47. 2007..These findings provide a molecular hypothesis for the long observed inhibitory effect of normal surrounding cells on breast cancer development... - Commutability of NIST SRM 1955 Homocysteine and Folate in Frozen Human Serum with selected total homocysteine immunoassays and enzymatic assaysBryant C Nelson
National Institute of Standards and Technology, Biochemical Science Division, Gaithersburg, MD 20899 0001, USA
Clin Chim Acta 395:99-105. 2008..NIST has performed an international, interlaboratory assessment of SRM 1955 commutability; results are reported for tHcy only... - Inhibition of the tumor necrosis factor-alpha pathway is radioprotective for the lungMing Zhang
Department of Radiation Oncology, University of Michigan School of Medicine, Ann Arbor, Michigan 48109 5582, USA
Clin Cancer Res 14:1868-76. 2008..Radiation-induced lung toxicity limits the delivery of high-dose radiation to thoracic tumors. Here, we investigated the potential of inhibiting the tumor necrosis factor-alpha (TNF-alpha) pathway as a novel radioprotection strategy... - Extended operation for thoracic malignancies invading superior vena cava and/or innominate veinChun-Bo Zhai
Department of Cardiothoracic Surgery, Second Xiangya Hospital, Central South University, Changsha 410011, China
Chin Med J (Engl) 120:1277-80. 2007 - Ca-stimulated type 8 adenylyl cyclase is required for rapid acquisition of novel spatial information and for working/episodic-like memoryMing Zhang
Department of Physiology, Michigan State University, East Lansing, Michigan 48824, USA
J Neurosci 28:4736-44. 2008.... - Atorvastatin downregulates BMP-2 expression induced by oxidized low-density lipoprotein in human umbilical vein endothelial cellsMing Zhang
Department of Cardiology, Second Xiangya Hospital, Central South University, Changsha Hunan, China
Circ J 72:807-12. 2008..The present study investigates the effects of ox-LDL on BMP-2 expression. Furthermore, the influence of atorvastatin on ox-LDL-induced BMP-2 expression is also examined... - Rho signaling inhibitor, Y-27632, inhibits invasiveness of metastastic hepatocellular carcinoma in a mouse modelFeng Xue
Organ Transplantation Center, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China
Chin Med J (Engl) 120:2304-7. 2007 - V(D)J recombinase binding and cleavage of cryptic recombination signal sequences identified from lymphoid malignanciesMing Zhang
Department of Medical Microbiology and Immunology, Creighton University Medical Center, Omaha, Nebraska 68178, USA
J Biol Chem 283:6717-27. 2008..In contrast, Hox11 and SCL are nicked but not cleaved efficiently in vitro, and cleavage at other adventitious sites in plasmid substrates may also limit the ability to detect recombination activity at these cRSSs in cell culture... - Nestin expression defines both glial and neuronal progenitors in postnatal sympathetic gangliaHuilin Shi
Department of Biochemistry and Cancer Biology, University of Toledo Health Science Campus, Toledo, Ohio 43614, USA
J Comp Neurol 508:867-78. 2008..Together, these results establish nestin as a common marker for sympathetic neuronal and glial progenitor cells and delineate the cellular basis for the generation and maturation of sympathetic satellite cells... - Peroxisome proliferator-activated receptor gamma agonists inhibit the proliferation and invasion of human colon cancer cellsDan Shen
Department 1 of Internal Medicine and Geriatrics, Zhongnan Hospital, Wuhan University, Wuhan, PR China
Postgrad Med J 83:414-9. 2007..This study was designed to examine the effects of PPAR-gamma agonists on the proliferation and invasion of two colon cancer cells to identify the role of PPAR-gamma in colon cancer growth and metastasis... - BTNL2, a butyrophilin/B7-like molecule, is a negative costimulatory molecule modulated in intestinal inflammationHeather A Arnett
Inflammation, Amgen, Seattle, WA 98119, USA
J Immunol 178:1523-33. 2007..These data suggest a role for BTNL2 as a negative costimulatory molecule with implications for inflammatory disease... - Reduction of intracellular pH inhibits the expression of VEGF in K562 cells after targeted inhibition of the Na+/H+ exchangerBingyan He
Pediatrics Department of Zhongnan Hospital, Wuhan University, East Lake Road, Wuhan, Hubei Province 430071, PR China
Leuk Res 31:507-14. 2007..These data strongly suggested that the expression of VEGF mRNA and protein in K562 cells was inhibited accompanying its reduction in pHi value after targeted inhibition of NHE1... - Functional activity of natural antibody is altered in Cr2-deficient miceRussell R Reid
Department of Pathology, Harvard Medical School, Boston, MA 02115, USA
J Immunol 169:5433-40. 2002..These results suggest that complement receptors CD21/CD35 are important in maintenance of the B-1 cell repertoire to some, but not all, specificities... - Potent activity of soluble B7RP-1-Fc in therapy of murine tumors in syngeneic hostsGulshan Ara
Department of Pharmacology, Amgen Inc, One Amgen Center Drive, Thousand Oaks, CA 91320, USA
Int J Cancer 103:501-7. 2003..As expected, T cells appeared to be targeted by B7RP-1-Fc treatment. Thus, the administration of soluble B7RP-1-Fc may have therapeutic value in generating or enhancing anti-tumor activity in a clinical setting... - Census of genes expressed in porcine embryos and reproductive tissues by mining an expressed sequence tag database based on human genesZhihua Jiang
Department of Animal Sciences, Washington State University, Pullman 99164, USA
Biol Reprod 69:1177-82. 2003..The census provides a panel of transcripts in a broad sense that can be used as targets to study the mechanisms involved in embryo development and reproduction in pigs and other mammals, including humans... - Ionizing radiation increases adenovirus uptake and improves transgene expression in intrahepatic colon cancer xenograftsMing Zhang
Department of Radiation Oncology, Ann Arbor, Michigan 48109 0582, USA
Mol Ther 8:21-8. 2003..4-fold after a 25-Gy treatment. These data suggest that a combination of regional radiation treatment with adenovirus gene therapy is a rational strategy for improving adenoviral targeting and transgene expression in tumors... - Changes in the proportion and number of Pax(7+ve) and MF20(+ve) myoblasts during chick myogenesis in the head and limbAntonio S J Lee
Department of Anatomy and Structural Biology, University of Otago, Dunedin, New Zealand
Int J Dev Biol 48:31-8. 2004..Moreover, we have found that the proportion of terminally differentiated myoblasts is maintained at a low level (less than 3%) during primary and secondary myogenesis... - Quantitative comparison of plantar foot shapes under different weight-bearing conditionsBonnie Yuk San Tsung
Jockey Club Rehabilitation Engineering Centre, The Hong Kong Polytechnic University, Hong Kong, China
J Rehabil Res Dev 40:517-26. 2003..7% +/- 4.9%, and decreases in the arch height of 20.0% +/- 9.2% and arch angle of 41.2% +/- 16.2%. The findings may be useful for considering the change of foot shape in the selection of shoe size and shoe or insole design... - Role of stem cell homing in myocardial regenerationMarc S Penn
Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
Int J Cardiol 95:S23-5. 2004.... - Effects of fluoride on lipid peroxidation, DNA damage and apoptosis in human embryo hepatocytesAi Guo Wang
Department of Environmental Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei, China
Biomed Environ Sci 17:217-22. 2004..To investigate the effects of fluoride on lipid peroxidation, DNA damage and apoptosis in human embryo hepatocyte L-02 cells... - Improving conformational searches by geometric screeningMing Zhang
Department of Biostatistics and Applied Mathematics, The University of Texas M D Anderson Cancer Center Houston, TX 77030, USA
Bioinformatics 21:624-30. 2005..We propose adding a geometric screening phase before an energy minimization procedure so that only conformations that geometrically fit in the binding site will be prompted for energy calculation... - 5-fluorouracil and hydroxyurea enhance adenovirus-mediated transgene expression in colon and hepatocellular carcinoma cellsXiao W Huang
Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109-0582, USA
J Cancer Res Clin Oncol 131:184-90. 2005..CONCLUSIONS: Our findings suggest that it may be possible to improve tumor cell transduction by adenovirus using chemotherapy... - Murine hindlimb reperfusion injury can be initiated by a self-reactive monoclonal IgMWilliam G Austen
Department of Surgery, Harvard Medical School, The Brigham and Women's Hospital, Boston, MA 02115, USA
Surgery 136:401-6. 2004..IgM and C3 deposition was found only on injured muscle of WT mice or Cr2-/- mice reconstituted with CM22 or WT serum. CONCLUSION: A single clone of self-reactive IgM, CM22, can initiate complement-dependent I/R injury... - Ionizing radiation-induced adenovirus infection is mediated by Dynamin 2Jun Qian
Department of Radiation Oncology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA
Cancer Res 65:5493-7. 2005.... - Activation of bone morphogenetic protein-6 gene transcription in MCF-7 cells by estrogenMing Zhang
Laboratory of Molecular Medicines, Medical College, Nankai University, Tianjin 300071, China
Chin Med J (Engl) 118:1629-36. 2005..CONCLUSION: Estrogen induces BMP-6 expression in human ER+ breast cancer cell line MCF-7 through its receptor ERalpha binding on 1/2 ERE element in the BMP-6 promoter... - Identification of the target self-antigens in reperfusion injuryMing Zhang
CBR Institute for Biomedical Research, Inc, Harvard Medical School, Boston, MA 02115, USA
J Exp Med 203:141-52. 2006..These results identify a novel pathway in which the innate response to a highly conserved self-antigen expressed as a result of hypoxic stress results in tissue destruction... - Attenuation of skeletal muscle reperfusion injury with intravenous 12 amino acid peptides that bind to pathogenic IgMRodney K Chan
From the Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston
Surgery 139:236-43. 2006..This indicates that the antibodies that initiate reperfusion injury have specificity only for P8-related antigens. This could also indicate that the variety of relevant ischemic antigens is quite restricted... - [Alteration of expression of survivin in HL-60 cells treated with chemotherapeutic drugs]Yao-hui Wu
Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
Zhongguo Shi Yan Xue Ye Xue Za Zhi 14:347-50. 2006..This phenomenon may be associated with the resistance in chemotherapy for leukemia. On the other hand, As2O3 shows a different mechanism that may play a significant role to reverse resistance... - Targeting maspin in endothelial cells to induce cell apoptosisJeremy S Schaefer
Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA
Expert Opin Ther Targets 10:401-8. 2006..A separate study showed the ability of maspin to induce apoptosis in tumour-specific endothelial cells. Taken together, these studies demonstrate the potential use of maspin as a viable anticancer therapeutic agent... - High and selective expression of yeast cytosine deaminase under a carcinoembryonic antigen promoter-enhancerMukesh K Nyati
Department of Radiation Oncology, University of Michigan, 1500 East Medical Center Drive, Ann Arbor, MI 48109-0010, USA
Cancer Res 62:2337-42. 2002..These findings suggest that the CEA promoter-enhancer strategy confers specificity while preserving activity and is worth exploring in additional animal and, potentially, clinical trials...