Li Yang

Summary

Affiliation: Baylor College of Medicine
Country: USA

Publications

  1. pmc Amyloid precursor protein regulates Cav1.2 L-type calcium channel levels and function to influence GABAergic short-term plasticity
    Li Yang
    Huffington Center on Aging, Baylor College of Medicine, Houston, Texas 77030, USA
    J Neurosci 29:15660-8. 2009
  2. pmc Presynaptic and postsynaptic interaction of the amyloid precursor protein promotes peripheral and central synaptogenesis
    Zilai Wang
    Huffington Center on Aging, Baylor College of Medicine, Houston, Texas 77030, USA
    J Neurosci 29:10788-801. 2009
  3. pmc Convergence of presenilin- and tau-mediated pathways on axonal trafficking and neuronal function
    Erica Peethumnongsin
    Huffington Center on Aging, Baylor College of Medicine, Houston, Texas 77030, USA
    J Neurosci 30:13409-18. 2010
  4. ncbi request reprint Role of APP and Aβ in synaptic physiology
    Zilai Wang
    Huffington Center on Aging, Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    Curr Alzheimer Res 9:217-26. 2012
  5. pmc Amyolid precursor protein mediates presynaptic localization and activity of the high-affinity choline transporter
    Baiping Wang
    Huffington Center on Aging and Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA
    Proc Natl Acad Sci U S A 104:14140-5. 2007
  6. pmc Selective clearance of aberrant tau proteins and rescue of neurotoxicity by transcription factor EB
    Vinicia A Polito
    Huffington Center on Aging, Baylor College of Medicine, Houston, TX, USA
    EMBO Mol Med 6:1142-60. 2014
  7. pmc NFκB-activated astroglial release of complement C3 compromises neuronal morphology and function associated with Alzheimer's disease
    Hong Lian
    Huffington Center on Aging, Houston, TX 77030, USA Department of Molecular and Human Genetics, Houston, TX 77030, USA
    Neuron 85:101-15. 2015
  8. doi request reprint A chymotrypsin-like serine protease cDNA involved in food protein digestion in the common cutworm, Spodoptera litura: Cloning, characterization, developmental and induced expression patterns, and localization
    Chun Zhang
    Guangdong Provincial Key Laboratory of Biotechnology for Plant Development, School of Life Sciences, South China Normal University, Guangzhou 510631, China
    J Insect Physiol 56:788-99. 2010
  9. pmc Disruption of the NF-κB/IκBα Autoinhibitory Loop Improves Cognitive Performance and Promotes Hyperexcitability of Hippocampal Neurons
    David J Shim
    Huffington Center on Aging, Baylor College of Medicine, Houston, TX 77030, USA
    Mol Neurodegener 6:42. 2011

Collaborators

  • Hui Zheng
  • Hui Chen Lu
  • Virginia M Y Lee
  • Joanna L Jankowsky
  • Andrea Ballabio
  • Robia G Pautler
  • Lin Liu
  • Akihiko Takashima
  • Zilai Wang
  • Baiping Wang
  • David J Shim
  • Hong Lian
  • Vinicia A Polito
  • Chun Zhang
  • Erica Peethumnongsin
  • Lu Sun
  • Angie C A Chiang
  • Giulio Taglialatela
  • Allysa Cole
  • Stephanie W Fowler
  • JENNIFER RODRIGUEZ-RIVERA
  • Yin Xu
  • Heidi Martini-Stoica
  • Marco Sardiello
  • Michela Palmieri
  • Alberto di Ronza
  • Daniel B Swartzlander
  • Hongmei Li
  • Paul J Chiao
  • Jeffrey L Noebels
  • J Graham Reed
  • Songnian Hu
  • Sichun Zheng
  • Qili Feng
  • Shu Tao
  • Verena Kallhoff-Munoz
  • Daohua Zhou
  • Lingyun Hu
  • Zhou Songyang
  • Qinxi Guo
  • Nadia Aithmitti

Detail Information

Publications9

  1. pmc Amyloid precursor protein regulates Cav1.2 L-type calcium channel levels and function to influence GABAergic short-term plasticity
    Li Yang
    Huffington Center on Aging, Baylor College of Medicine, Houston, Texas 77030, USA
    J Neurosci 29:15660-8. 2009
    ..2. These results provide a direct link between APP and calcium signaling and might help explain how altered APP regulation leads to changes in synaptic function that occur with AD...
  2. pmc Presynaptic and postsynaptic interaction of the amyloid precursor protein promotes peripheral and central synaptogenesis
    Zilai Wang
    Huffington Center on Aging, Baylor College of Medicine, Houston, Texas 77030, USA
    J Neurosci 29:10788-801. 2009
    ..We postulate that transsynaptic APP interaction modulates its synaptic function and that perturbed APP synaptic adhesion activity may contribute to synaptic dysfunction and AD pathogenesis...
  3. pmc Convergence of presenilin- and tau-mediated pathways on axonal trafficking and neuronal function
    Erica Peethumnongsin
    Huffington Center on Aging, Baylor College of Medicine, Houston, Texas 77030, USA
    J Neurosci 30:13409-18. 2010
    ..Our results strongly support a convergent role for PS and tau in axonal transport and neuronal survival and function and implicate their misregulation as a contributor to AD pathogenesis...
  4. ncbi request reprint Role of APP and Aβ in synaptic physiology
    Zilai Wang
    Huffington Center on Aging, Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    Curr Alzheimer Res 9:217-26. 2012
    ..Here, we review the roles that APP and Aβ play at the synapses, with particular focus on recent findings for the importance of APP in synaptogenesis and synaptic function...
  5. pmc Amyolid precursor protein mediates presynaptic localization and activity of the high-affinity choline transporter
    Baiping Wang
    Huffington Center on Aging and Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA
    Proc Natl Acad Sci U S A 104:14140-5. 2007
    ..These results identify a physiological activity of APP in cholinergic neurons, and our data indicate that deregulation of APP function may contribute to cholinergic impairment and AD pathogenesis...
  6. pmc Selective clearance of aberrant tau proteins and rescue of neurotoxicity by transcription factor EB
    Vinicia A Polito
    Huffington Center on Aging, Baylor College of Medicine, Houston, TX, USA
    EMBO Mol Med 6:1142-60. 2014
    ..The specificity and efficacy of TFEB in mediating the clearance of toxic Tau species makes it an attractive therapeutic target for treating diseases of tauopathy including AD. ..
  7. pmc NFκB-activated astroglial release of complement C3 compromises neuronal morphology and function associated with Alzheimer's disease
    Hong Lian
    Huffington Center on Aging, Houston, TX 77030, USA Department of Molecular and Human Genetics, Houston, TX 77030, USA
    Neuron 85:101-15. 2015
    ..Therefore, dysregulation of neuron-glia interaction through NFκB/C3/C3aR signaling may contribute to synaptic dysfunction in AD, and C3aR antagonists may be therapeutically beneficial. ..
  8. doi request reprint A chymotrypsin-like serine protease cDNA involved in food protein digestion in the common cutworm, Spodoptera litura: Cloning, characterization, developmental and induced expression patterns, and localization
    Chun Zhang
    Guangdong Provincial Key Laboratory of Biotechnology for Plant Development, School of Life Sciences, South China Normal University, Guangzhou 510631, China
    J Insect Physiol 56:788-99. 2010
    ..The results suggest that this Slctlp2 gene may be involved in digestive process of food proteins during the feeding stages of the larval development...
  9. pmc Disruption of the NF-κB/IκBα Autoinhibitory Loop Improves Cognitive Performance and Promotes Hyperexcitability of Hippocampal Neurons
    David J Shim
    Huffington Center on Aging, Baylor College of Medicine, Houston, TX 77030, USA
    Mol Neurodegener 6:42. 2011
    ..abstract:..