Yong Xu

Summary

Affiliation: Baylor College of Medicine
Country: USA

Publications

  1. pmc Cross-Talk between Metabolism and Reproduction: The Role of POMC and SF1 Neurons
    Yong Xu
    Department of Pediatrics, Children s Nutrition Research Center, Baylor College of Medicine Houston, TX, USA
    Front Endocrinol (Lausanne) 2:98. 2011
  2. pmc Steroid receptor coactivator-1 mediates estrogenic actions to prevent body weight gain in female mice
    Liangru Zhu
    Children s Nutrition Research Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77479, USA
    Endocrinology 154:150-8. 2013
  3. pmc Central nervous control of energy and glucose balance: focus on the central melanocortin system
    Yong Xu
    Children s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA
    Ann N Y Acad Sci 1243:1-14. 2011
  4. pmc PI3K in the ventromedial hypothalamic nucleus mediates estrogenic actions on energy expenditure in female mice
    Kenji Saito
    Children s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA
    Sci Rep 6:23459. 2016
  5. pmc Visualizing estrogen receptor-α-expressing neurons using a new ERα-ZsGreen reporter mouse line
    Kenji Saito
    Children s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030
    Metabolism 65:522-32. 2016
  6. pmc The ERα-PI3K Cascade in Proopiomelanocortin Progenitor Neurons Regulates Feeding and Glucose Balance in Female Mice
    Liangru Zhu
    Children s Nutrition Research Center L Z, P X, X C, Y Y, A O H, Y Xi, K S, X Y, F Z, H D, C W, C Y, M F, Y Xu, Department of Pediatrics Diabetes Research Center P S, L C, Department of Medicine and Department of Molecular and Cellular Biology L C, Y Xu, Baylor College of Medicine, and Brown Foundation Institute of Molecular Medicine Q T, University of Texas Health Science Center at Houston, Houston, Texas 77030 Department of Gastroenterology L Z, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, People s Republic of China Medical College of Qingdao University C Y, Qingdao 266020, People s Republic of China Department of Cancer Biology S A K, Vontz Center for Molecular Studies, University of Cincinnati, College of Medicine, Cincinnati, Ohio 45267 Department of Pathology J Z, Harvard Medical School, Col. Vicentina. Iztapalapa
    Endocrinology 156:4474-91. 2015
  7. pmc Glutamate mediates the function of melanocortin receptor 4 on Sim1 neurons in body weight regulation
    Yuanzhong Xu
    Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX 77030, USA
    Cell Metab 18:860-70. 2013
  8. pmc Distinct hypothalamic neurons mediate estrogenic effects on energy homeostasis and reproduction
    Yong Xu
    Children s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA
    Cell Metab 14:453-65. 2011
  9. pmc Meta-chlorophenylpiperazine enhances leptin sensitivity in diet-induced obese mice
    Chunling Yan
    Children s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA
    Br J Pharmacol 172:3510-21. 2015
  10. pmc New inducible genetic method reveals critical roles of GABA in the control of feeding and metabolism
    Fantao Meng
    Children s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030
    Proc Natl Acad Sci U S A 113:3645-50. 2016

Collaborators

  • Makoto Fukuda
  • Lawrence Chan
  • Qi Wu
  • Deborah J Clegg
  • Joel K Elmquist
  • Xinfu Guan
  • Douglas G Burrin
  • Kenji Saito
  • Pingwen Xu
  • Qingchun Tong
  • Xiaofeng Yan
  • Yongjie Yang
  • Liangru Zhu
  • Antentor Othrell Hinton
  • Chunmei Wang
  • Chunling Yan
  • Fantao Meng
  • Yanlin He
  • Jean Zhao
  • Fang Zou
  • Xuemei Shi
  • Dollada Srisai
  • Richard D Palmiter
  • Valery Belakhov
  • Likai Yu
  • Monica Farias
  • Gang Shu
  • Timor Baasov
  • Yong Han
  • Hongfang Ding
  • Yan Xia
  • Pradip Saha
  • Xuehong Cao
  • Sohaib A Khan
  • Benny Chang
  • Lan Liao
  • Xiaojie Li
  • BERT W O'MALLEY
  • Jianming Xu
  • Yi Wang
  • Depei Li
  • Defa Li
  • Jean J Zhao
  • Fuguo Zhou

Detail Information

Publications11

  1. pmc Cross-Talk between Metabolism and Reproduction: The Role of POMC and SF1 Neurons
    Yong Xu
    Department of Pediatrics, Children s Nutrition Research Center, Baylor College of Medicine Houston, TX, USA
    Front Endocrinol (Lausanne) 2:98. 2011
    ..In this review, we will examine the potential mechanisms of neuronal communication between POMC, SF1, and gonadotropin-releasing hormone neurons in the regulation of metabolism and reproduction...
  2. pmc Steroid receptor coactivator-1 mediates estrogenic actions to prevent body weight gain in female mice
    Liangru Zhu
    Children s Nutrition Research Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77479, USA
    Endocrinology 154:150-8. 2013
    ..Collectively our results indicate that SRC1 is functionally required to mediate the antiobesity effects of estrogen-ERα signals...
  3. pmc Central nervous control of energy and glucose balance: focus on the central melanocortin system
    Yong Xu
    Children s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA
    Ann N Y Acad Sci 1243:1-14. 2011
    ..These findings suggest that targeting the specific branches of melanocortin circuits may be potential avenues to combat the current obesity and diabetes epidemics...
  4. pmc PI3K in the ventromedial hypothalamic nucleus mediates estrogenic actions on energy expenditure in female mice
    Kenji Saito
    Children s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA
    Sci Rep 6:23459. 2016
    ..Collectively, our results indicate that PI3K activity in VMH neurons plays a physiologically relevant role in mediating estrogenic actions on energy expenditure in females. ..
  5. pmc Visualizing estrogen receptor-α-expressing neurons using a new ERα-ZsGreen reporter mouse line
    Kenji Saito
    Children s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030
    Metabolism 65:522-32. 2016
    ..However, complex intracellular processes in these ERα-expressing neurons are difficult to unravel, due to the lack of strategy to visualize ERα-expressing neurons, especially in unfixed brain tissues...
  6. pmc The ERα-PI3K Cascade in Proopiomelanocortin Progenitor Neurons Regulates Feeding and Glucose Balance in Female Mice
    Liangru Zhu
    Children s Nutrition Research Center L Z, P X, X C, Y Y, A O H, Y Xi, K S, X Y, F Z, H D, C W, C Y, M F, Y Xu, Department of Pediatrics Diabetes Research Center P S, L C, Department of Medicine and Department of Molecular and Cellular Biology L C, Y Xu, Baylor College of Medicine, and Brown Foundation Institute of Molecular Medicine Q T, University of Texas Health Science Center at Houston, Houston, Texas 77030 Department of Gastroenterology L Z, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, People s Republic of China Medical College of Qingdao University C Y, Qingdao 266020, People s Republic of China Department of Cancer Biology S A K, Vontz Center for Molecular Studies, University of Cincinnati, College of Medicine, Cincinnati, Ohio 45267 Department of Pathology J Z, Harvard Medical School, Col. Vicentina. Iztapalapa
    Endocrinology 156:4474-91. 2015
    ..Together, our results indicate that an ERα-PI3K cascade in POMC progenitor neurons mediates estrogenic actions to suppress food intake and improve insulin sensitivity. ..
  7. pmc Glutamate mediates the function of melanocortin receptor 4 on Sim1 neurons in body weight regulation
    Yuanzhong Xu
    Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX 77030, USA
    Cell Metab 18:860-70. 2013
    ..Thus, this study establishes glutamate as the primary neurotransmitter that mediates MC4Rs on Sim1 neurons in body weight regulation...
  8. pmc Distinct hypothalamic neurons mediate estrogenic effects on energy homeostasis and reproduction
    Yong Xu
    Children s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA
    Cell Metab 14:453-65. 2011
    ..These results indicate that estrogens act on distinct hypothalamic ERα neurons to regulate different aspects of energy homeostasis and reproduction...
  9. pmc Meta-chlorophenylpiperazine enhances leptin sensitivity in diet-induced obese mice
    Chunling Yan
    Children s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA
    Br J Pharmacol 172:3510-21. 2015
    ..Hence, the development of strategies to increase leptin sensitivity is of high priority in the field of obesity research...
  10. pmc New inducible genetic method reveals critical roles of GABA in the control of feeding and metabolism
    Fantao Meng
    Children s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030
    Proc Natl Acad Sci U S A 113:3645-50. 2016
    ..This new genetic technique will augment current tools used to elucidate mechanisms underlying many physiological and neurological processes. ..
  11. pmc Central GLP-2 enhances hepatic insulin sensitivity via activating PI3K signaling in POMC neurons
    Xuemei Shi
    USDA ARS Children s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA
    Cell Metab 18:86-98. 2013
    ..Thus, CNS GLP-2 plays a key physiological role in the control of HGP through activating PI3K-dependent modulation of membrane excitability and nuclear transcription of POMC neurons in the brain. ..