Genomes and Genes


R A Waterland


Affiliation: Baylor College of Medicine
Country: USA


  1. Waterland R, Travisano M, Tahiliani K, Rached M, Mirza S. Methyl donor supplementation prevents transgenerational amplification of obesity. Int J Obes (Lond). 2008;32:1373-9 pubmed publisher
  2. Yu D, Gadkari M, Zhou Q, Yu S, Gao N, Guan Y, et al. Postnatal epigenetic regulation of intestinal stem cells requires DNA methylation and is guided by the microbiome. Genome Biol. 2015;16:211 pubmed publisher
  3. Kessler N, Van Baak T, Baker M, Laritsky E, Coarfa C, Waterland R. CpG methylation differences between neurons and glia are highly conserved from mouse to human. Hum Mol Genet. 2016;25:223-32 pubmed publisher
  4. Eclarinal J, Zhu S, Baker M, Piyarathna D, Coarfa C, Fiorotto M, et al. Maternal exercise during pregnancy promotes physical activity in adult offspring. FASEB J. 2016;30:2541-8 pubmed publisher
    ..Eclarinal, J. D., Zhu, S., Baker, M. S., Piyarathna, D. B., Coarfa, C., Fiorotto, M. L., Waterland, R. A. Maternal exercise during pregnancy promotes physical activity in adult offspring. ..
  5. Van Baak T, Coarfa C, Dugué P, Fiorito G, Laritsky E, Baker M, et al. Epigenetic supersimilarity of monozygotic twin pairs. Genome Biol. 2018;19:2 pubmed publisher
    ..More broadly, epigenetic supersimilarity is a previously unrecognized phenomenon that may contribute to the phenotypic similarity of monozygotic twins. ..
  6. request reprint
    Waterland R, Dolinoy D, Lin J, Smith C, Shi X, Tahiliani K. Maternal methyl supplements increase offspring DNA methylation at Axin Fused. Genesis. 2006;44:401-6 pubmed
    ..Our results indicate that stochastic establishment of epigenotype at metastable epialleles is, in general, labile to methyl donor nutrition, and such influences are not limited to early embryonic development. ..
  7. Silver M, Kessler N, Hennig B, Dominguez Salas P, Laritsky E, Baker M, et al. Independent genomewide screens identify the tumor suppressor VTRNA2-1 as a human epiallele responsive to periconceptional environment. Genome Biol. 2015;16:118 pubmed publisher
    ..More broadly, the list of candidate metastable epialleles provides a resource for future studies of epigenetic variation and human disease. ..