Regis A Vilchez

Summary

Affiliation: Baylor College of Medicine
Country: USA

Publications

  1. ncbi Detection of polyomavirus simian virus 40 tumor antigen DNA in AIDS-related systemic non-Hodgkin lymphoma
    Regis A Vilchez
    Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA
    J Acquir Immune Defic Syndr 29:109-16. 2002
  2. ncbi Conventional epidemiology and the link between SV40 and human cancers
    Regis A Vilchez
    Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA
    Lancet Oncol 4:188-91. 2003
  3. ncbi Simian virus 40 in human cancers
    Regis A Vilchez
    Department of Medicine, Section of Infectious Diseases, Baylor College of Medicine, BCM 286, Room N1319, One Baylor Plaza, Houston, TX 77030, USA
    Am J Med 114:675-84. 2003
  4. ncbi Standardized detection of SV40 by real time quantitative polymerase chain reaction
    Regis A Vilchez
    Department of Medicine, Baylor Center for AIDS Research, Baylor College of Medicine, USA
    Haematologica 90:6. 2005
  5. ncbi Association between simian virus 40 and non-Hodgkin lymphoma
    Regis A Vilchez
    Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA
    Lancet 359:817-23. 2002
  6. ncbi AIDS-related systemic non-Hodgkin's lymphoma at a large community program
    Regis A Vilchez
    Department of Medicine, Baylor Center for AIDS Research, Baylor College of Medicine, Houston, Texas 77030, USA
    AIDS Res Hum Retroviruses 18:237-42. 2002
  7. ncbi The clinical epidemiology of Hodgkin lymphoma in HIV-infected patients in the highly active antiretroviral therapy (HAART) era
    Regis A Vilchez
    Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA
    Medicine (Baltimore) 82:77-81. 2003
  8. ncbi Viral regulatory region effects on vertical transmission of polyomavirus SV40 in hamsters
    Niraj C Patel
    Department of Molecular Virology and Microbiology, Baylor College of Medicine, One Baylor Plaza, MS BCM385, Houston, TX 77030 3411, USA
    Virology 386:94-101. 2009
  9. ncbi Simian virus 40 tumor antigen expression and immunophenotypic profile of AIDS-related non-Hodgkin's lymphoma
    Regis A Vilchez
    Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA
    Virology 342:38-46. 2005
  10. ncbi Detection of polyomavirus SV40 in tonsils from immunocompetent children
    Niraj C Patel
    Department of Pediatrics, Section of Infectious Diseases, Baylor College of Medicine, Houston, TX 77030, United States
    J Clin Virol 43:66-72. 2008

Collaborators

Detail Information

Publications44

  1. ncbi Detection of polyomavirus simian virus 40 tumor antigen DNA in AIDS-related systemic non-Hodgkin lymphoma
    Regis A Vilchez
    Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA
    J Acquir Immune Defic Syndr 29:109-16. 2002
    ..None of the S-NHL samples were positive for both Epstein-Barr virus DNA and SV40 DNA. Further studies of the possible role of SV40 in the pathogenesis of S-NHL are warranted...
  2. ncbi Conventional epidemiology and the link between SV40 and human cancers
    Regis A Vilchez
    Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA
    Lancet Oncol 4:188-91. 2003
    ..In this essay, we consider the unique features of SV40 infection in humans and examine the limitations of conventional studies that seek to disprove the aetiological link with human cancer...
  3. ncbi Simian virus 40 in human cancers
    Regis A Vilchez
    Department of Medicine, Section of Infectious Diseases, Baylor College of Medicine, BCM 286, Room N1319, One Baylor Plaza, Houston, TX 77030, USA
    Am J Med 114:675-84. 2003
    ..However, the small samples and lack of control groups in some reports have made it difficult to assess their reliability...
  4. ncbi Standardized detection of SV40 by real time quantitative polymerase chain reaction
    Regis A Vilchez
    Department of Medicine, Baylor Center for AIDS Research, Baylor College of Medicine, USA
    Haematologica 90:6. 2005
  5. ncbi Association between simian virus 40 and non-Hodgkin lymphoma
    Regis A Vilchez
    Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA
    Lancet 359:817-23. 2002
    ..We aimed to identify which one of the three polyomaviruses able to infect human beings (simian virus 40 [SV40], JC virus, and BK virus) was associated with non-Hodgkin lymphoma...
  6. ncbi AIDS-related systemic non-Hodgkin's lymphoma at a large community program
    Regis A Vilchez
    Department of Medicine, Baylor Center for AIDS Research, Baylor College of Medicine, Houston, Texas 77030, USA
    AIDS Res Hum Retroviruses 18:237-42. 2002
    ..In addition, this opportunistic malignancy is associated with significant mortality. Therefore, it is necessary to develop a better understanding of the pathogenesis of this disease...
  7. ncbi The clinical epidemiology of Hodgkin lymphoma in HIV-infected patients in the highly active antiretroviral therapy (HAART) era
    Regis A Vilchez
    Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA
    Medicine (Baltimore) 82:77-81. 2003
    ..These results suggest that Hodgkin lymphoma has a low incidence in HIV-infected patients receiving HAART, but the malignancy is an aggressive disease with unfavorable clinical outcome in these patients...
  8. ncbi Viral regulatory region effects on vertical transmission of polyomavirus SV40 in hamsters
    Niraj C Patel
    Department of Molecular Virology and Microbiology, Baylor College of Medicine, One Baylor Plaza, MS BCM385, Houston, TX 77030 3411, USA
    Virology 386:94-101. 2009
    ..These results indicate that SV40 replicates in hamsters, vertical transmission of SV40 can occur, and the viral regulatory region influences transmission...
  9. ncbi Simian virus 40 tumor antigen expression and immunophenotypic profile of AIDS-related non-Hodgkin's lymphoma
    Regis A Vilchez
    Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA
    Virology 342:38-46. 2005
    ..2/12, 17%; P = 0.05). This study shows that SV40 gene expression occurs in a fraction of cells in some B-cell lymphomas among patients with HIV/AIDS...
  10. ncbi Detection of polyomavirus SV40 in tonsils from immunocompetent children
    Niraj C Patel
    Department of Pediatrics, Section of Infectious Diseases, Baylor College of Medicine, Houston, TX 77030, United States
    J Clin Virol 43:66-72. 2008
    ..BK and JC viruses establish persistent infections in humans, and evidence suggests that SV40 can infect humans, as well. Whether persistence occurs in the lymphoid system is unknown...
  11. ncbi Polyomavirus infection and its impact on renal function and long-term outcomes after lung transplantation
    Lora D Thomas
    Department of Medicine, Vanderbilt University School of Medicine, 1161 21st Avenue South, Nashville, TN 37232, USA
    Transplantation 88:360-6. 2009
    ..Polyomavirus infection causes nephropathy after kidney transplantation but has not been thoroughly investigated in nonrenal organ transplantation...
  12. ncbi SV40 lymphomagenesis in Syrian golden hamsters
    Adrienne L McNees
    Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA
    Virology 384:114-24. 2009
    ....
  13. ncbi Association between SV40 and non-Hodgkin's lymphoma
    Janet S Butel
    Department of Molecular Virology and Microbiology, Baylor College of Medicine, Mail Stop BCM385, One Baylor Plaza, Houston, TX 77030, USA
    Leuk Lymphoma 44:S33-9. 2003
    ..We conclude that SV40 is significantly associated with some types of NHL and that lymphomas should be added to the types of human cancers associated with SV40...
  14. ncbi A prospective longitudinal study of polyomavirus shedding in lung-transplant recipients
    Lora D Thomas
    Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    J Infect Dis 195:442-9. 2007
    ..Polyomavirus infection causes renal dysfunction after kidney transplantation, but it has not been thoroughly investigated in nonrenal solid-organ transplantation...
  15. ncbi Polyomavirus SV40 infections in Kazakhstan
    Zhannat Z Nurgalieva
    Department of Medicine, Baylor College of Medicine, Houston, TX, USA
    J Infect 50:142-8. 2005
    ..As increasing evidence indicates an association of SV40 with selected types of human malignancies, prospective studies are needed to examine the risk of SV40 infection with the development of neoplasias...
  16. ncbi Specific and quantitative detection of human polyomaviruses BKV, JCV, and SV40 by real time PCR
    Adrienne L McNees
    Department of Molecular Virology and Microbiology, Baylor College of Medicine, One Baylor Plaza, MS BCM-385, Houston, TX 77030, USA
    J Clin Virol 34:52-62. 2005
    ..CONCLUSION: These assays provide a technique for rapid and specific quantification of polyomavirus genomes per cell in human samples...
  17. ncbi Molecular and clinical perspectives of polyomaviruses: emerging evidence of importance in non-kidney transplant populations
    Regis A Vilchez
    Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA
    Liver Transpl 12:1457-63. 2006
    ....
  18. ncbi Influence of the viral regulatory region on tumor induction by simian virus 40 in hamsters
    Vojtech Sroller
    Department of Molecular Virology and Microbiology, Baylor College of Medicine, Mail Stop BCM385, One Baylor Plaza, Houston, TX 77030, USA
    J Virol 82:871-9. 2008
    ..This study shows that SV40 strains differ in their biological properties, suggests that SV40 replicates to some level in hamsters, and indicates that the outcome of an SV40 infection may depend on the viral strain present...
  19. ncbi Polyomavirus simian virus 40 infection associated with nephropathy in a lung-transplant recipient
    Aaron Milstone
    Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Transplantation 77:1019-24. 2004
    ..No serum or tissue samples were available from his 27-year-old donor. DISCUSSION: This report shows that SV40 is circulating in the community and can cause nephropathy in transplant patients...
  20. ncbi Simian virus 40 in posttransplant lymphoproliferative disorders
    Regis A Vilchez
    Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA
    Hum Pathol 37:1130-6. 2006
    ..These results suggest that SV40 may be associated with a small subset of PTLD cases. Additional studies are needed to determine the role of SV40 in EBV-negative PTLD...
  21. ncbi Emergent human pathogen simian virus 40 and its role in cancer
    Regis A Vilchez
    Department of Molecular Virology and Microbiology, Baylor College of Medicine, Mail Stop BCM-385, One Baylor Plaza, Houston, TX 77030, USA
    Clin Microbiol Rev 17:495-508, table of contents. 2004
    ..quot; This review analyzes the accumulating data that indicate that SV40 is a pathogen which has a possible etiologic role in human malignancies. Future research directions are considered...
  22. ncbi SV40 in human brain cancers and non-Hodgkin's lymphoma
    Regis A Vilchez
    Department of Molecular Virology and Microbiology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    Oncogene 22:5164-72. 2003
    ....
  23. ncbi Polyomavirus SV40 and AIDS-related systemic non-Hodgkin's lymphoma
    Regis A Vilchez
    Department of Molecular Virology and Microbiology and Baylor-UTHouston Center for AIDS Research, Baylor College of Medicine, Houston, TX, USA
    Cancer Treat Res 133:215-40. 2007
  24. ncbi Polyomavirus JC urinary shedding in kidney and liver transplant recipients associated with reduced creatinine clearance
    Shimon Kusne
    Department of Medicine, Mayo Clinic Arizona, Scottsdale, Arizona, USA
    J Infect Dis 206:875-80. 2012
    ..Less is known about dynamics of John Cunningham virus (JCV) in nonkidney organ transplant patients...
  25. ncbi Differential ability of two simian virus 40 strains to induce malignancies in weanling hamsters
    Regis A Vilchez
    Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA
    Virology 330:168-77. 2004
    ....
  26. ncbi Parainfluenza virus infection in adult lung transplant recipients: an emergent clinical syndrome with implications on allograft function
    Regis A Vilchez
    Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Am J Transplant 3:116-20. 2003
    ..In addition, controlled studies are needed to evaluate the efficacy of aerosolized ribavarin in the treatment of parainfluenza virus infection and to determine whether vaccines may be effective in these high-risk patients...
  27. ncbi Simian virus 40 and its association with human lymphomas
    Regis A Vilchez
    Department of Medicine, Baylor College of Medicine, Mail Stop BCM-385, One Baylor Plaza, Houston, TX 77030, USA
    Curr Oncol Rep 5:372-9. 2003
    ..This review examines the data implicating SV40 in the pathogenesis of human lymphomas and discusses future directions to define the causative role for SV40 in these malignancies...
  28. ncbi Pathogenesis and management of polyomavirus infection in transplant recipients
    Eun Jeong Kwak
    Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Clin Infect Dis 35:1081-7. 2002
    ..Clinical syndromes related to polyomavirus infection are summarized in the present review, and strategies for the management of patients who receive transplants are discussed...
  29. ncbi Viruses from nonhuman primates
    Regis A Vilchez
    Emerg Infect Dis 12:1802-3; author reply 1803. 2006
  30. ncbi Limitations of epidemiological and serologic studies addressing simian virus 40 and non-Hodgkin's lymphoma
    Regis A Vilchez
    Cancer Invest 24:333-6. 2006
  31. ncbi Polyomaviruses in solid-organ transplant recipients
    Regis A Vilchez
    Transplantation 74:579-80; author reply 580-1. 2002
  32. ncbi Lymphoproliferative disorders in Costa Rica and simian virus 40
    Armando Meneses
    Department of Pathology, Hospital San Juan de Dios, San Jose, Costa Rica
    Haematologica 90:1635-42. 2005
    ..Of note, 20% of patients with SV40-related lymphomas were born in the 1970s and 1980s. INTERPRETATION AND CONCLUSIONS. These results indicate that SV40 is significantly associated with some B-cell neoplasms in Costa Rica today...
  33. ncbi Re: Cancer incidence in Denmark following exposure to poliovirus vaccine contaminated with simian virus 40
    Regis A Vilchez
    J Natl Cancer Inst 95:1249; author reply 1250. 2003
  34. ncbi Polyomavirus JCV excretion and genotype analysis in HIV-infected patients receiving highly active antiretroviral therapy
    John A Lednicky
    Baylor Coll Med, Houston, TX
    AIDS 17:801-7. 2003
    ..As the common types of JCV excreted varied among ethnic groups, JCV genotypes associated with progressive multifocal leukoencephalopathy may reflect demographics of those infected patient populations...
  35. ncbi The dynamics of herpesvirus and polyomavirus reactivation and shedding in healthy adults: a 14-month longitudinal study
    Paul D Ling
    Baylor Coll Med, Houston, TX
    J Infect Dis 187:1571-80. 2003
    ..50). Thus, adults independently control persistent viruses, which display discordant, sporadic reactivations...
  36. ncbi Re: Trends in U.S. pleural mesothelioma incidence rates following simian virus 40 contamination of early poliovirus vaccines
    Regis A Vilchez
    J Natl Cancer Inst 95:687; author reply 689. 2003
  37. ncbi Systemic non-Hodgkin lymphoma in HIV-infected patients in the era of highly active antiretroviral therapy
    Regis A Vilchez
    Blood 99:4250-1. 2002
  38. ncbi Epstein-Barr virus DNA loads in adult human immunodeficiency virus type 1-infected patients receiving highly active antiretroviral therapy
    Paul D Ling
    Baylor Coll Med, Houston, TX
    Clin Infect Dis 37:1244-9. 2003
    ..Additional studies are needed to determine whether EBV-specific CD4+ and CD8+ cells play a role in the pathogenesis of EBV in HIV-1-infected patients receiving HAART...
  39. ncbi Re: Lack of serologic evidence for prevalent simian virus 40 infection in humans
    Regis A Vilchez
    J Natl Cancer Inst 96:633; author reply 633-4. 2004
  40. ncbi Plasmablastic lymphomas and plasmablastic plasma cell myelomas have nearly identical immunophenotypic profiles
    Francisco Vega
    Department of Pathology, Baylor College of Medicine [corrected] Houston, TX [corrected] USA
    Mod Pathol 18:806-15. 2005
    ..These results do not support the suggestion in the WHO classification that plasmablastic lymphoma is a variant of diffuse large B-cell lymphoma...
  41. ncbi Polyomavirus SV40 infection and lymphomas in Spain
    Regis A Vilchez
    Int J Cancer 107:505-6; author reply 507-8. 2003
  42. ncbi An overview of the biology and viral pathogenesis of lymphoproliferative disorders in HIV-infected patients
    Regis A Vilchez
    Res Initiat Treat Action 9:14-8. 2003
  43. ncbi Polyomaviruses in kidney transplant recipients
    Regis A Vilchez
    Am J Transplant 2:481. 2002
  44. ncbi Simian virus 40 infection in lymphoproliferative disorders
    Regis A Vilchez
    Lancet 361:1565; author reply 1565-6. 2003