James Versalovic

Summary

Affiliation: Baylor College of Medicine
Country: USA

Publications

  1. pmc The Genboree Microbiome Toolset and the analysis of 16S rRNA microbial sequences
    Kevin Riehle
    Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA
    BMC Bioinformatics 13:S11. 2012
  2. pmc Probiotics stimulate enterocyte migration and microbial diversity in the neonatal mouse intestine
    Geoffrey A Preidis
    Texas Children s Hospital, Feigin Center, Ste 830, 1102 Bates Ave, Houston, Texas 77030, USA
    FASEB J 26:1960-9. 2012
  3. pmc Probiotic Lactobacillus reuteri biofilms produce antimicrobial and anti-inflammatory factors
    Sara E Jones
    Department of Pathology, Baylor College of Medicine, Houston, Texas 77030, USA
    BMC Microbiol 9:35. 2009
  4. pmc Relationships among ciprofloxacin, gatifloxacin, levofloxacin, and norfloxacin MICs for fluoroquinolone-resistant Escherichia coli clinical isolates
    Lauren Becnel Boyd
    Antimicrob Agents Chemother 53:229-34. 2009
  5. pmc Mechanisms of probiosis and prebiosis: considerations for enhanced functional foods
    Delphine M A Saulnier
    Department of Pathology, Baylor College of Medicine, Houston, TX, USA
    Curr Opin Biotechnol 20:135-41. 2009
  6. pmc Vancomycin MICs for Staphylococcus aureus vary by detection method and have subtly increased in a pediatric population since 2005
    Edward O Mason
    Section of Infectious Diseases, Department of Pediatrics, Baylor College of Medicine, and Infectious Disease Research Laboratory, Texas Children s Hospital, Houston, Texas 77030, USA
    J Clin Microbiol 47:1628-30. 2009
  7. doi request reprint Novel synergistic antibiofilm combinations for salvage of infected catheters
    Mohan Venkatesh
    Section of Neonatology, Department of Pediatrics, Texas Children s Hospital and Baylor College of Medicine, Houston, TX 77030, USA
    J Med Microbiol 58:936-44. 2009
  8. pmc Molecular microbiological methods in the diagnosis of neonatal sepsis
    Mohan Venkatesh
    Section of Neonatology, Department of Pediatrics, Texas Children s Hospital and Baylor College of Medicine, 6621 Fannin St, Houston, TX 77030, USA
    Expert Rev Anti Infect Ther 8:1037-48. 2010
  9. pmc Colonic mucosal DNA methylation, immune response, and microbiome patterns in Toll-like receptor 2-knockout mice
    Richard Kellermayer
    Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030 2399, USA
    FASEB J 25:1449-60. 2011

Collaborators

  • Mohan Venkatesh
  • Sheldon L Kaplan
  • Jennifer K Spinler
  • Lynn Zechiedrich
  • Edward O Mason
  • Scot E Dowd
  • Delphine M A Saulnier
  • G R Gibson
  • I Raad
  • Kevin Riehle
  • Geoffrey A Preidis
  • Toni Ann Mistretta
  • Richard Kellermayer
  • Sara E Jones
  • Lauren Becnel Boyd
  • Angela M Major
  • Andrew Jackson
  • María Alejandra Díaz
  • Kjersti Aagaard
  • Joseph F Petrosino
  • Cristian Coarfa
  • Sarah E Blutt
  • Sabeen Raza
  • Jun Ma
  • Robert Shulman
  • Arpit Tandon
  • Sameer Paithankar
  • Margaret E Conner
  • Milton J Finegold
  • Sriram Raghuraman
  • Aleksandar Milosavljevic
  • Susan F Venable
  • Kevin P Riehle
  • Tiffany D Schaible
  • R Alan Harris
  • Randy D Wolcott
  • Reka Szigeti
  • C Wayne Smith
  • Alfred Balasa
  • Zhijie Li
  • Nina Tatevian
  • Richard Sucgang
  • Sonia K Morgan-Linnell
  • Javier Rojo Jimenez
  • Richard J Hamill
  • Lori Banks Horton
  • David Steffen
  • Merry J Maynard

Detail Information

Publications9

  1. pmc The Genboree Microbiome Toolset and the analysis of 16S rRNA microbial sequences
    Kevin Riehle
    Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA
    BMC Bioinformatics 13:S11. 2012
    ..Installation, integration, and maintenance of the tools poses significant burden on many researchers and creates a barrier to adoption of microbiome analysis, particularly in translational settings...
  2. pmc Probiotics stimulate enterocyte migration and microbial diversity in the neonatal mouse intestine
    Geoffrey A Preidis
    Texas Children s Hospital, Feigin Center, Ste 830, 1102 Bates Ave, Houston, Texas 77030, USA
    FASEB J 26:1960-9. 2012
    ..These experiments identify two targets of probiosis in early development, the intestinal epithelium and the gut microbiome, and suggest novel mechanisms for probiotic strain-specific effects...
  3. pmc Probiotic Lactobacillus reuteri biofilms produce antimicrobial and anti-inflammatory factors
    Sara E Jones
    Department of Pathology, Baylor College of Medicine, Houston, Texas 77030, USA
    BMC Microbiol 9:35. 2009
    ....
  4. pmc Relationships among ciprofloxacin, gatifloxacin, levofloxacin, and norfloxacin MICs for fluoroquinolone-resistant Escherichia coli clinical isolates
    Lauren Becnel Boyd
    Antimicrob Agents Chemother 53:229-34. 2009
    ....
  5. pmc Mechanisms of probiosis and prebiosis: considerations for enhanced functional foods
    Delphine M A Saulnier
    Department of Pathology, Baylor College of Medicine, Houston, TX, USA
    Curr Opin Biotechnol 20:135-41. 2009
    ..A special focus will be given to the addition of prebiotics and probiotics in functional foods for infants and seniors...
  6. pmc Vancomycin MICs for Staphylococcus aureus vary by detection method and have subtly increased in a pediatric population since 2005
    Edward O Mason
    Section of Infectious Diseases, Department of Pediatrics, Baylor College of Medicine, and Infectious Disease Research Laboratory, Texas Children s Hospital, Houston, Texas 77030, USA
    J Clin Microbiol 47:1628-30. 2009
    ..3) was not different. We conclude that MICs for pediatric isolates have increased slightly since 2005 and therapeutic decisions based on vancomycin MICs need to be made by considering the methodology used...
  7. doi request reprint Novel synergistic antibiofilm combinations for salvage of infected catheters
    Mohan Venkatesh
    Section of Neonatology, Department of Pediatrics, Texas Children s Hospital and Baylor College of Medicine, Houston, TX 77030, USA
    J Med Microbiol 58:936-44. 2009
    ..Catheter-lock solutions of EDTA, NAC and ethanol alone or in combination with antibiotics may be used to salvage infected catheters, which will directly impact on patient morbidity and health-care costs...
  8. pmc Molecular microbiological methods in the diagnosis of neonatal sepsis
    Mohan Venkatesh
    Section of Neonatology, Department of Pediatrics, Texas Children s Hospital and Baylor College of Medicine, 6621 Fannin St, Houston, TX 77030, USA
    Expert Rev Anti Infect Ther 8:1037-48. 2010
    ..Molecular methods offer distinct advantages over blood cultures, including increased sensitivity and rapid diagnosis. However, diagnostic accuracy and cost-effectiveness should be established before implementation in clinical practice...
  9. pmc Colonic mucosal DNA methylation, immune response, and microbiome patterns in Toll-like receptor 2-knockout mice
    Richard Kellermayer
    Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030 2399, USA
    FASEB J 25:1449-60. 2011
    ..This manuscript highlights the intimate interrelationships between expression of immune-related genes and immunity pathways in the host with compositional and functional differences of the mammalian microbiome...

Research Grants12

  1. CATALASE IMMUNITY IN PRIMARY SCLEROSING CHOLANGITIS
    James Versalovic; Fiscal Year: 2005
    ..The proposed animal model will facilitate the evaluation of diagnostic and therapeutic strategies for PSC in vivo. ..
  2. Intestinal Lactobacillus and Mucosal Immunomodulation
    James Versalovic; Fiscal Year: 2010
    ..We seek to understand the mechanisms of action of beneficial intestinal bacteria so that new strains can be identified naturally or engineered for human medicine. ..
  3. Intestinal Lactobacillus and Mucosal Immunomodulation
    James Versalovic; Fiscal Year: 2009
    ..We seek to understand the mechanisms of action of beneficial intestinal bacteria so that new strains can be identified naturally or engineered for human medicine. ..
  4. Probiotic Lactobacillus-Mediated Suppression of TNF in Pediatric Crohn's Disease
    James Versalovic; Fiscal Year: 2007
    ..The identification of human signaling pathways regulated by probiotics will facilitate specification of targets for new anti-inflammatory compounds and may move probiotics from "alternative" to "mainstream" medicine. ..
  5. Intestinal Lactobacillus and Mucosal Immunomodulation
    James Versalovic; Fiscal Year: 2007
    ..We seek to understand the mechanisms of action of beneficial intestinal bacteria so that new strains can be identified naturally or engineered for human medicine. ..
  6. Reuteri LuxS in Probiosis for Early Childhood Caries
    James Versalovic; Fiscal Year: 2006
    ..2. Investigate the role of Lactobacillus reuteri (Reuteri) LuxS in regulation of biofilm-related gene expression and biofilm formation by early childhood caries-associated Streptococcus mutans (Mutans). ..
  7. Modulation of NF-kB Signaling by Immunoprobiotics
    James Versalovic; Fiscal Year: 2010
    ..Finally, a mouse model of intestinal inflammation will be used to explore which genes of beneficial bacteria are important for regulating intestinal immune responses in mammals. ..