S Umar

Summary

Affiliation: Baylor College of Medicine
Country: USA

Publications

  1. ncbi Dietary pectin and calcium inhibit colonic proliferation in vivo by differing mechanisms
    S Umar
    Division of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, The University of Texas Medical School, Houston, Texas, USA
    Cell Prolif 36:361-75. 2003
  2. ncbi Increased beta-catenin expression and nuclear translocation accompany cellular hyperproliferation in vivo
    J H Sellin
    Department of Internal Medicine, The University of Texas Medical School-Houston, 77030, USA
    Cancer Res 61:2899-906. 2001
  3. ncbi Activation of NF-kappaB is required for mediating proliferative and antiapoptotic effects of progastrin on proximal colonic crypts of mice, in vivo
    S Umar
    Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX 77555 1043, USA
    Oncogene 27:5599-611. 2008
  4. ncbi Increased nuclear translocation of catalytically active PKC-zeta during mouse colonocyte hyperproliferation
    S Umar
    Department of Integrative Biology, Pharmacology, and Physiology, University of Texas Health Science Center at Houston, Medical School, 77030, USA
    Am J Physiol Gastrointest Liver Physiol 279:G223-37. 2000

Collaborators

Detail Information

Publications4

  1. ncbi Dietary pectin and calcium inhibit colonic proliferation in vivo by differing mechanisms
    S Umar
    Division of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, The University of Texas Medical School, Houston, Texas, USA
    Cell Prolif 36:361-75. 2003
    ..TMCH is thus a diet-sensitive model for examining the effect of specific nutrients on molecular characteristics of the pre-neoplastic colonic epithelium...
  2. ncbi Increased beta-catenin expression and nuclear translocation accompany cellular hyperproliferation in vivo
    J H Sellin
    Department of Internal Medicine, The University of Texas Medical School-Houston, 77030, USA
    Cancer Res 61:2899-906. 2001
    ..These findings predict that an oncogenic signaling mechanism related to non-E-cadherin-bound beta-catenin is active in hyperproliferating native colonocytes and is similar to that recorded during the early stages of colon carcinogenesis...
  3. ncbi Activation of NF-kappaB is required for mediating proliferative and antiapoptotic effects of progastrin on proximal colonic crypts of mice, in vivo
    S Umar
    Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX 77555 1043, USA
    Oncogene 27:5599-611. 2008
    ..Thus, downregulation of NF-kappaB may significantly reduce the increased risk of colon carcinogenesis in response to PG...
  4. ncbi Increased nuclear translocation of catalytically active PKC-zeta during mouse colonocyte hyperproliferation
    S Umar
    Department of Integrative Biology, Pharmacology, and Physiology, University of Texas Health Science Center at Houston, Medical School, 77030, USA
    Am J Physiol Gastrointest Liver Physiol 279:G223-37. 2000
    ..These results suggest separate cellular and nuclear roles, respectively, for PKC-zeta in quiescent and mitotically active colonocytes. PKM-zeta may specifically act as a modulator of proliferation during TMCH...