Eroboghene E Ubogu

Summary

Affiliation: Baylor College of Medicine
Country: USA

Publications

  1. doi request reprint The molecular and biophysical characterization of the human blood-nerve barrier: current concepts
    Eroboghene E Ubogu
    Neuromuscular Immunopathology Research Laboratory, Department of Neurology, Baylor College of Medicine, Houston, TX 77030 3411, USA
    J Vasc Res 50:289-303. 2013
  2. doi request reprint Behavioral, electrophysiological, and histopathological characterization of a severe murine chronic demyelinating polyneuritis model
    Eroboghene E Ubogu
    Neuromuscular Immunopathology Research Laboratory, Department of Neurology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    J Peripher Nerv Syst 17:53-61. 2012
  3. ncbi request reprint Chemokine receptors as specific anti-inflammatory targets in peripheral nerves
    Eroboghene E Ubogu
    Neuromuscular Immunopathology Research Laboratory, Department of Neurology, Baylor College of Medicine, Houston, TX 77030 3411, USA
    Endocr Metab Immune Disord Drug Targets 11:141-53. 2011
  4. doi request reprint Development and characterization of a novel human in vitro blood-nerve barrier model using primary endoneurial endothelial cells
    Nejla Yosef
    Neuromuscular Immunopathology Research Laboratory, Department of Neurology, Baylor College of Medicine, Houston, Texas 77030 3411, USA
    J Neuropathol Exp Neurol 69:82-97. 2010
  5. pmc An immortalized human blood-nerve barrier endothelial cell line for in vitro permeability studies
    Nejla Yosef
    Department of Neurology, Baylor College of Medicine, Houston, TX 77030 3411, USA
    Cell Mol Neurobiol 33:175-86. 2013
  6. doi request reprint Dorsal caudal tail and sciatic motor nerve conduction studies in adult mice: technical aspects and normative data
    Robin H Xia
    Neuromuscular Immunopathology Research Laboratory, Department of Neurology, Baylor College of Medicine, One Baylor Plaza, Mailstop NB 302, Houston, Texas 77030 3411, USA
    Muscle Nerve 41:850-6. 2010
  7. doi request reprint Chemokine-dependent signaling pathways in the peripheral nervous system
    Eroboghene E Ubogu
    Neuromuscular Immunopathology Research Laboratory, Department of Neurology, Baylor College of Medicine, Houston, TX, USA
    Methods Mol Biol 1013:17-30. 2013
  8. pmc Transient brown adipocyte-like cells derive from peripheral nerve progenitors in response to bone morphogenetic protein 2
    Elizabeth A Salisbury
    Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX, USA
    Stem Cells Transl Med 1:874-85. 2012
  9. pmc α(M)β(2)-integrin-intercellular adhesion molecule-1 interactions drive the flow-dependent trafficking of Guillain-Barré syndrome patient derived mononuclear leukocytes at the blood-nerve barrier in vitro
    Nejla Yosef
    Neuromuscular Immunopathology Research Laboratory, Department of Neurology, Baylor College of Medicine, Houston, Texas 77030 3411, USA
    J Cell Physiol 227:3857-75. 2012
  10. doi request reprint GDNF restores human blood-nerve barrier function via RET tyrosine kinase-mediated cytoskeletal reorganization
    Nejla Yosef
    Neuromuscular Immunopathology Research Laboratory, Department of Neurology, Baylor College of Medicine, Houston, TX 77030 3411, USA
    Microvasc Res 83:298-310. 2012

Collaborators

Detail Information

Publications15

  1. doi request reprint The molecular and biophysical characterization of the human blood-nerve barrier: current concepts
    Eroboghene E Ubogu
    Neuromuscular Immunopathology Research Laboratory, Department of Neurology, Baylor College of Medicine, Houston, TX 77030 3411, USA
    J Vasc Res 50:289-303. 2013
    ..This review discusses current knowledge in this nascent and exciting field of microvascular biology. ..
  2. doi request reprint Behavioral, electrophysiological, and histopathological characterization of a severe murine chronic demyelinating polyneuritis model
    Eroboghene E Ubogu
    Neuromuscular Immunopathology Research Laboratory, Department of Neurology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    J Peripher Nerv Syst 17:53-61. 2012
    ..Immunohistochemistry confirmed macrophage-predominant inflammation. This study verifies SAPP as a progressive, unremitting chronic inflammatory demyelinating polyneuropathy with axonal loss...
  3. ncbi request reprint Chemokine receptors as specific anti-inflammatory targets in peripheral nerves
    Eroboghene E Ubogu
    Neuromuscular Immunopathology Research Laboratory, Department of Neurology, Baylor College of Medicine, Houston, TX 77030 3411, USA
    Endocr Metab Immune Disord Drug Targets 11:141-53. 2011
    ....
  4. doi request reprint Development and characterization of a novel human in vitro blood-nerve barrier model using primary endoneurial endothelial cells
    Nejla Yosef
    Neuromuscular Immunopathology Research Laboratory, Department of Neurology, Baylor College of Medicine, Houston, Texas 77030 3411, USA
    J Neuropathol Exp Neurol 69:82-97. 2010
    ....
  5. pmc An immortalized human blood-nerve barrier endothelial cell line for in vitro permeability studies
    Nejla Yosef
    Department of Neurology, Baylor College of Medicine, Houston, TX 77030 3411, USA
    Cell Mol Neurobiol 33:175-86. 2013
    ..39 vs. 0.52 %) by the BNB cell line. This cell line retained essential molecular and biophysical properties suitable for in vitro peripheral nerve permeability studies...
  6. doi request reprint Dorsal caudal tail and sciatic motor nerve conduction studies in adult mice: technical aspects and normative data
    Robin H Xia
    Neuromuscular Immunopathology Research Laboratory, Department of Neurology, Baylor College of Medicine, One Baylor Plaza, Mailstop NB 302, Houston, Texas 77030 3411, USA
    Muscle Nerve 41:850-6. 2010
    ..This would assist in the process of translational therapeutic drug design in neuromuscular disorders...
  7. doi request reprint Chemokine-dependent signaling pathways in the peripheral nervous system
    Eroboghene E Ubogu
    Neuromuscular Immunopathology Research Laboratory, Department of Neurology, Baylor College of Medicine, Houston, TX, USA
    Methods Mol Biol 1013:17-30. 2013
    ..This chapter describes a flow-dependent human leukocyte-BNB trafficking assay and the reliable induction of EAN in female SJL/J mice as tools to study pro-inflammatory chemokine-dependent signaling in peripheral nerves...
  8. pmc Transient brown adipocyte-like cells derive from peripheral nerve progenitors in response to bone morphogenetic protein 2
    Elizabeth A Salisbury
    Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX, USA
    Stem Cells Transl Med 1:874-85. 2012
    ....
  9. pmc α(M)β(2)-integrin-intercellular adhesion molecule-1 interactions drive the flow-dependent trafficking of Guillain-Barré syndrome patient derived mononuclear leukocytes at the blood-nerve barrier in vitro
    Nejla Yosef
    Neuromuscular Immunopathology Research Laboratory, Department of Neurology, Baylor College of Medicine, Houston, Texas 77030 3411, USA
    J Cell Physiol 227:3857-75. 2012
    ....
  10. doi request reprint GDNF restores human blood-nerve barrier function via RET tyrosine kinase-mediated cytoskeletal reorganization
    Nejla Yosef
    Neuromuscular Immunopathology Research Laboratory, Department of Neurology, Baylor College of Medicine, Houston, TX 77030 3411, USA
    Microvasc Res 83:298-310. 2012
    ..These observations provide insights into the regulation of human BNB function during recovery from peripheral nerve injury...
  11. doi request reprint Clinical, electrophysiological and pathologic correlations in a severe murine experimental autoimmune neuritis model of Guillain-Barré syndrome
    Robin H Xia
    Neuromuscular Immunopathology Research Laboratory, Department of Neurology, Baylor College of Medicine, Houston, Texas, United States
    J Neuroimmunol 219:54-63. 2010
    ..The high induction rates, as well as pathologic similarities with AIDP make sm-EAN a robust model to study the pathogenesis of human peripheral nerve inflammation using objective outcome measures...
  12. doi request reprint A case of severe chronic progressive axonal polyradiculoneuropathy temporally associated with anti-CV2/CRMP5 antibodies
    Yousef Hannawi
    Department of Neurology, Baylor College of Medicine, Houston, TX, USA
    J Clin Neuromuscul Dis 15:13-8. 2013
    ..We report a fatal case of severe chronic progressive axonal polyradiculoneuropathy in association with this antibody...
  13. doi request reprint CCR2 Gene Deletion and Pharmacologic Blockade Ameliorate a Severe Murine Experimental Autoimmune Neuritis Model of Guillain-Barré Syndrome
    Furong Yuan
    Neuromuscular Immunopathology Research Laboratory, Department of Neurology, Baylor College of Medicine, Houston, Texas, United States of America
    PLoS ONE 9:e90463. 2014
    ..CCR2 mediates pathogenic hematogenous monocyte trafficking into peripheral nerves, with consequential demyelination in sm-EAN. CCR2 is amenable to pharmacologic blockade, making it a plausible drug target for GBS. ..
  14. doi request reprint The role of chemokines in Guillain-Barré syndrome
    Sharon Chiang
    Department of Statistics, Rice University, Houston, Texas, USA
    Muscle Nerve 48:320-30. 2013
    ..Despite current treatments, outcomes are suboptimal. Specific chemokine receptor antagonists have the potential to be efficacious against pathogenic leukocyte trafficking in GBS...
  15. pmc VEGF-A165 potently induces human blood-nerve barrier endothelial cell proliferation, angiogenesis, and wound healing in vitro
    Chetan Lakshmana Reddy
    Neuromuscular Immunopathology Research Laboratory, Department of Neurology, Baylor College of Medicine, One Baylor Plaza, Mailstop NB302, Houston, TX 77030 3411, USA
    Cell Mol Neurobiol 33:789-801. 2013
    ..VEGF-A165 may be an important mitogen necessary for human BNB development and recovery in response to peripheral nerve injury...