Affiliation: Baylor College of Medicine
Chiu H, Somvanshi S, Patel E, Chen T, Singh V, Zorman B, et al
. Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context. Cell Rep. 2018;23:297-312.e12 pubmed publisher
..Our analysis indicates that, although most lncRNAs are dysregulated in a tumor-specific manner, some, including OIP5-AS1, TUG1, NEAT1, MEG3, and TSIX, synergistically dysregulate cancer pathways in multiple tumor contexts. ..
Ustianenko D, Chiu H, Treiber T, Weyn Vanhentenryck S, Treiber N, Meister G, et al
. LIN28 Selectively Modulates a Subclass of Let-7 MicroRNAs. Mol Cell. 2018;71:271-283.e5 pubmed publisher
..Thus, CSD binding sites amplify the regulatory effects of LIN28. ..
Chiu H, MartÃnez M, Bansal M, Subramanian A, Golub T, Yang X, et al
. High-throughput validation of ceRNA regulatory networks. BMC Genomics. 2017;18:418 pubmed publisher
..Our results suggest that the expression of a significant fraction of cancer genes may be regulated by ceRNA interactions in each of the two tumor contexts. ..
Bansal M, Mendiratta G, Anand S, Kushwaha R, Kim R, Kustagi M, et al
. Direct ChIP-Seq significance analysis improves target prediction. BMC Genomics. 2015;16 Suppl 5:S4 pubmed publisher