W N Suki
Affiliation: Baylor College of Medicine
- Effects of sevelamer and calcium-based phosphate binders on mortality in hemodialysis patientsW N Suki
Renal Section, Department of Medicine, The Kidney Institute, Baylor College of Medicine, Houston, Texas 77054, USA
Kidney Int 72:1130-7. 2007..There was a suggestion that sevelamer was associated with lower overall, but not cardiovascular-linked, mortality in older patients. We suggest that further research is needed to confirm these findings...
- Effects of sevelamer and calcium-based phosphate binders on mortality in hemodialysis patients: results of a randomized clinical trialWadi N Suki
Kidney Institute and Department of Medicine, Baylor College of Medicine, Houston, Texas 77054, USA
J Ren Nutr 18:91-8. 2008..Sevelamer, a phosphate-binding polymer, attenuates the progression of arterial calcification; it is unknown whether this improves outcomes...
- Diuretic resistanceW N Suki
Renal Section, Department of Medicine, Baylor College of Medicine, Houston, Tex, USA
Miner Electrolyte Metab 25:28-31. 1999..Using diuretic combinations to systematically inhibit absorption in the proximal tubule, Henle's loop, distal convoluted tubule, and connecting/collecting tubule will usually effect diuresis in all but the most refractory of cases...
- p38 kinase activity is essential for osmotic induction of mRNAs for HSP70 and transporter for organic solute betaine in Madin-Darby canine kidney cellsD Sheikh-Hamad
Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA
J Biol Chem 273:1832-7. 1998..In addition, the transduction pathways mediating HSP70 mRNA induction by different stresses appear to be divergent; osmotic induction of HSP70 is p38 kinase-dependent, while thermal induction is not...
- Renal cell apoptosis in chronic obstructive uropathy: the roles of caspasesL D Truong
Renal Pathology Laboratory, Department of Pathology, The Methodist Hospital and Baylor College of Medicine, Houston, Texas 77030, USA
Kidney Int 60:924-34. 2001..Caspases are cytosolic enzymes that belong to a 12-member family and serve as effector molecules for apoptosis. The role of individual caspases in mediating renal cell apoptosis in kidneys with COU is studied...
- The remission of post-transplant nephrotic syndrome clinicopathologic characterizationLuan D Truong
Department of Pathology, Renal Section, Baylor College of Medicine and The Methodist Hospital, Houston, Texas, USA
Am J Transplant 2:975-82. 2002..It is often associated with minimal-change diseases and less frequently with other glomerular lesions, including acute glomerulitis. Reversible post-transplant NS does not have an adverse effect on the renal allografts...
- Chronic allograft nephropathy and nephrotic range proteinuriaVenkataraman Ramanathan
Renal Section, MED Veterans Affairs Medical Center and O Brien Kidney Research Center, Baylor College of Medicine, Houston, TX 77030, USA
Clin Transplant 19:413-7. 2005..13%). PTx-NP related to CAN was associated with poor allograft survival, irrespective of the time of onset of presentation, especially when renal function was reduced at the time of biopsy...
- Calcium oxalate deposition in renal allografts: morphologic spectrum and clinical implicationsLuan D Truong
Department of Pathology, Renal Section, Baylor College of Medicine, The Methodist Hospital, Houston, TX, USA
Am J Transplant 4:1338-44. 2004..CaOx deposition in renal allografts can be classified in different categories with distinctive morphologic features and clinical implications...
- De novo minimal change disease associated with reversible post-transplant nephrotic syndrome. A report of five cases and review of literatureAlireza A Zafarmand
Department of Pathology, Renal Section, Baylor College of Medicine and The Methodist Hospital, Houston, TX 77030, USA
Clin Transplant 16:350-61. 2002..De novo MCD has characteristic clinical and pathologic features. It represents an important but hitherto underemphasized cause of post-transplant NS, which is potentially reversible and does not adversely affect the renal transplants...
- Post-transplant nephrotic syndrome: A comprehensive clinicopathologic studyUlkem Yakupoglu
Department of Pathology, Renal Section, Baylor College of Medicine, and The Methodist Hospital, The kidney Institute of Houston, Texas 77030, USA
Kidney Int 65:2360-70. 2004..1 vs. 2.5 g/day). Graft survival improved with NS remission (88% vs. 18%). CONCLUSION: Post-Tx NS displays distinctive clinicopathologic features with pathogenetic and therapeutic implications...
- Immunoglobulin therapy for plasma cell-rich rejection in the renal allograftHoracio E Adrogue
Nephrology Section, Baylor College of Medicine, The Methodist Hospital, Houston, TX, USA
Transplantation 82:567-9. 2006..We report four episodes of PCAR in two patients who responded well to IVIG with improvement in renal function...
- Lymphoid cell proliferation in renal transplants: biologic and diagnostic implicationsHulya Akgun
Department of Pathology, The Methodist Hospital, Houston, TX, USA
Clin Transplant 21:472-80. 2007..Proliferation of IIC involves predominantly T lymphocytes. These observations provide support for the concept of in situ alloimmunization, and facilitate the diagnosis of ACR...
- A truncated-dose regimen of daclizumab for prevention of acute rejection in kidney transplant recipients: a single-center experienceLiliana Soltero
The Kidney Institute, 1415 La Concha Lane, Houston, TX 77054, USA
Transplantation 78:1560-3. 2004..09). The incidence of CAN was 6.6% in group 1 and 13% in group 2 (P = 0.63). These data suggest that the truncated dose of daclizumab is as effective as the standard regimen for AR prophylaxis...
- Are gadolinium-based contrast media nephrotoxic? A renal biopsy studyHulya Akgun
Departments of Pathology, Nephropathology Service, The Methodist Hospital, Houston, TX 77030, USA
Arch Pathol Lab Med 130:1354-7. 2006..This case emphasizes the potential nephrotoxicity of gadolinium-based contrast media and suggests that the nephrotoxicity is related to potentially reversible acute tubular cell injury...
- Sirolimus may promote thrombotic microangiopathyJocelyne A Saikali
Depajtments of Pathology and Medicine, The Methodist Hospital and Baylor College of Medicine, Houston, Texas, USA
Am J Transplant 3:229-30. 2003