Research Topics
| J M SorofSummaryAffiliation: Baylor College of Medicine Country: USA Publications
Research Grants
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Detail Information
Publications
Ambulatory blood pressure and left ventricular mass index in hypertensive childrenJonathan M Sorof
Department of Pediatrics, University of Texas Houston Medical School, Houston, TX 77030, USA
Hypertension 39:903-8. 2002..015). These data suggest ambulatory blood pressure monitoring may be useful for the clinical assessment of hypertensive children by identifying those at high risk for the presence of end organ injury...
Carotid ultrasonography for detection of vascular abnormalities in hypertensive childrenJonathan M Sorof
Department of Pediatrics, University of Texas Health Science Center at Houston, Houston, Texas 77030, USA
Pediatr Nephrol 18:1020-4. 2003..53, P<0.001). These results provide further evidence that vasculopathy occurs in association with known cardiovascular risk factors such as hypertension and obesity during childhood...
Beta-blocker/thiazide combination for treatment of hypertensive children: a randomized double-blind, placebo-controlled trialJonathan M Sorof
Division of Pediatric Nephrology and Hypertension, Medical School, University of Texas Houston, 6431 Fannin Street, Room 3 124, Houston, TX 77030, USA
Pediatr Nephrol 17:345-50. 2002....
Cardiovascular risk factors and sequelae in hypertensive children identified by referral versus school-based screeningJonathan M Sorof
Department of Pediatrics, University of Texas Houston Medical School, Houston, Tex 77030, USA
Hypertension 43:214-8. 2004....
Prevalence and consequence of systolic hypertension in childrenJonathan M Sorof
Department of Pediatrics, University of Texas Houston School of Medicine, 77030, USA
Am J Hypertens 15:57S-60S. 2002..In addition, trials of antihypertensive medications in children should incorporate SBP hypertension into study inclusion criteria...
Evaluation of white coat hypertension in children: importance of the definitions of normal ambulatory blood pressure and the severity of casual hypertensionJ M Sorof
Department of Pediatrics, University of Texas Houston, Memorial Hermann Hospital, USA
Am J Hypertens 14:855-60. 2001..In addition, these data confirm in children the finding in adults that WCH is highly prevalent when casual hypertension is borderline or mild, but uncommon when moderate or severe...
Overweight, ethnicity, and the prevalence of hypertension in school-aged childrenJonathan M Sorof
Department of Pediatrics, Division of Pediatric Nephrology and Hypertension, University of Texas Health Science Center, Houston, Texas, USA
Pediatrics 113:475-82. 2004..To describe the current prevalence of pediatric hypertension and the relationships between gender, ethnicity, overweight, and blood pressure...
Characteristics of hypertensive children identified by primary care referral compared with school-based screeningJonathan M Sorof
Department of Pediatrics, Division of Pediatric Nephrology and Hypertension, University of Texas Houston Medical School, 6431 Fannin Street, Room 3 124, Houston, TX 77030, USA
J Pediatr 144:485-9. 2004..All subjects underwent 24-hour ambulatory blood pressure (BP) monitoring. White coat hypertension was defined as 24-hour mean BP <95th percentile and BP load <25%...
Systolic hypertension in children: benign or beware?J M Sorof
Division of Pediatric Nephrology and Hypertension, University of Texas Houston, Medical School, Room 3 124, 6431 Fannin Street, Houston, TX 77030, USA
Pediatr Nephrol 16:517-25. 2001..In addition, trials of anti-hypertensive medications in children should incorporate SBP hypertension into study inclusion criteria...
Ambulatory blood pressure measurementsJ M Sorof
Section of Nephrology and Hypertension, Department of Pediatrics, University of Texas Houston, Medical School, Houston, Texas 77030, USA
Curr Opin Pediatr 13:133-7. 2001..These studies will assist in the practice of evidence-based medicine regarding pediatric hypertension that will improve the long-term care that pediatricians provide to their patients...
White coat hypertension in childrenJ M Sorof
Section of Nephrology and Hypertension, Department of Pediatrics, University of Texas Houston School of Medicine, Houston 77030, USA
Blood Press Monit 5:197-202. 2000..If hypertension is confirmed by ABPM, further evaluation should be tailored to the individual patient depending on the age, severity of hypertension, associated risk factors, and presence of end-organ injury...
Obesity hypertension in children: a problem of epidemic proportionsJonathan Sorof
Division of Pediatric Nephrology and Hypertension, Department of Pediatrics, University of Texas Houston Medical School, Houston, Tex 77030, USA
Hypertension 40:441-7. 2002..Obesity in childhood should be considered a chronic medical condition that is likely to require long-term management. Ultimately, prevention of obesity and its complications, including hypertension, is the goal...
Abnormal 24-hour blood pressure patterns in children after renal transplantationJ M Sorof
Department of Pediatrics, University of Texas Houston, School of Medicine, USA
Am J Kidney Dis 35:681-6. 2000..These BP disturbances may shorten renal allograft survival and predispose children to long-term hypertensive end-organ damage...
Serial estimation of glomerular filtration rate in children after renal transplantJ M Sorof
Texas Children s Hospital, Baylor College of Medicine, Houston, Texas, USA
Pediatr Nephrol 13:737-41. 1999..These results are similar to those reported in multi-center studies using the outcome variable of graft failure and suggest that serial eGFR may be valid as an outcome variable to study chronic renal allograft dysfunction in children...
Antihypertensive medication and renal allograft failure: a North American Pediatric Renal Transplant Cooperative Study reportJ M Sorof
Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA
J Am Soc Nephrol 10:1324-30. 1999..These data suggest that hypertension after renal transplantation in children, as evidenced by use of anti-HTN medications, is associated with increased rates of subsequent graft failure...
Efficacy and safety of extended release metoprolol succinate in hypertensive children 6 to 16 years of age: a clinical trial experienceDonald L Batisky
Department of Pediatrics, Section of Nephrology, Columbus Children s Hospital, The Ohio State University College of Medicine, Columbus, Ohio 43205, USA
J Pediatr 150:134-9, 139.e1. 2007..To evaluate the efficacy, tolerability, and blood pressure (BP) lowering effect of extended release metoprolol succinate (ER metoprolol) in children 6 to 16 years of age with established hypertension...
Ambulatory blood pressure monitoring and interdialytic weight gain in children receiving chronic hemodialysisJ M Sorof
Texas Children s Hospital, Baylor College of Medicine, Houston, TX, USA
Am J Kidney Dis 33:667-74. 1999..We conclude that in children receiving chronic hemodialysis: (1) sleep BP decreases are attenuated and sleep BP loads are elevated, (2) casual BP correlates poorly with ABPM, and (3) interdialytic weight and BP are related...
Prevalence of hypertension and pre-hypertension among adolescentsKaren L McNiece
Department of Pediatrics, Division of Pediatric Nephrology and Hypertension, University of Texas Houston, School of Medicine, Houston, Texas 77057, USA
J Pediatr 150:640-4, 644.e1. 2007..To determine the prevalence of hypertension and pre-hypertension on the basis of the 2004 National High Blood Pressure Education Program Working Group guidelines in an adolescent school-screening population...
Carotid artery intimal-medial thickness and left ventricular hypertrophy in children with elevated blood pressureJonathan M Sorof
Department of Pediatrics, University of Texas Medical School at Houston, Houston, Texas 77030, USA
Pediatrics 111:61-6. 2003..To determine the association between carotid artery intimal-medial thickness (cIMT) and left ventricular mass index (LVMI) in children with elevated blood pressure...
Left ventricular hypertrophy in hypertensive adolescents: analysis of risk by 2004 National High Blood Pressure Education Program Working Group staging criteriaKaren L McNiece
Department of Pediatrics, Division of Pediatric Nephrology and Hypertension, School of Medicine, University of Texas, Houston, TX 77057, USA
Hypertension 50:392-5. 2007....
Ambulatory blood pressure monitoring in pediatric end-stage renal disease: chronic dialysis and transplantationJ M Sorof
Department of Pediatrics, Renal Section, Baylor College of Medicine, Houston, Texas, USA
Blood Press Monit 4:171-4. 1999..Further studies are therefore needed to establish the utility of ABPM for the management of hypertension and prevention of end-organ injury in children with ESRD...
Natural logarithmic estimates of Kt/V in the pediatric hemodialysis populationS L Goldstein
Baylor College of Medicine, Texas Children s Hospital, Houston 77030, USA
Am J Kidney Dis 33:518-22. 1999..The simplicity of this formula should allow for the use of Kt/V as the best measure to study the relationship between delivered dialysis dose and outcomes in children...
Isolated systolic hypertension, obesity, and hyperkinetic hemodynamic states in childrenJonathan M Sorof
Department of Pediatrics, University of Texas-Houston Medical School, Houston, Texas 77030, USA
J Pediatr 140:660-6. 2002..05). CONCLUSIONS: The findings of increased heart rate and BP variability in obese children with isolated systolic hypertension suggest that sympathetic nervous system hyperactivity may contribute to its pathogenesis...
Screening for eligibility in the study of antihypertensive medication in children: experience from the Ziac Pediatric Hypertension StudyJ M Sorof
University of Texas Houston, Medical School, 77030, USA
Am J Hypertens 14:783-7. 2001..As experience is limited in children to guide the planning of these studies, we reviewed data from the Ziac Pediatric Hypertension Study to determine patterns of early study termination to help future studies...
Evaluation and prediction of urea rebound and equilibrated Kt/V in the pediatric hemodialysis populationS L Goldstein
Renal Section, Baylor College of Medicine, Houston, TX, USA
Am J Kidney Dis 34:49-54. 1999..We have devised an easy and accurate method to predict equilibrated BUN and calculate double-pool Kt/V in children, which requires only an additional 15-minute posttreatment BUN sample...
Long-term treatment of focal segmental glomerulosclerosis in children with cyclosporine given as a single daily doseA S Chishti
Department of Pediatrics, Renal Section, Baylor College of Medicine and Texas Children's Hospital, Houston, TX 77030, USA
Am J Kidney Dis 38:754-60. 2001..Single daily low-dose CsA appears to be effective for long-term treatment of children with FSGS and NS, with fewer side effects than twice-daily dosing...
Overweight as a risk factor in children: a focus on ethnicityShawna D Nesbitt
University of Texas Southwestern Medical Center at Dallas, Dallas 75390 8899, USA
Ethn Dis 14:94-110. 2004..This summary article reviews the data on cardiovascular risk factors and overweight in ethnic children and adolescents, and culminates in a practical algorithm for evaluating overweight children for cardiovascular risk...
Effect of stimulants on 24-h ambulatory blood pressure in children with ADHD: a double-blind, randomized, cross-over trialJoshua A Samuels
Pediatric Nephrology and Hypertension, The University of Texas Health Science Center at Houston, USA
Pediatr Nephrol 21:92-5. 2006..This potential cardiovascular risk should be balanced against the beneficial behavioral effects of this class of medication...
Research Grants
- Blood Pressure and Stimulant Medications in ChildrenJonathan Sorof; Fiscal Year: 2003..If so, physicians who prescribe these medications must increased awareness of the need to monitor blood pressure carefully in these children. ..
- End-Organ Injury in Hypertensive ChildrenJonathan Sorof; Fiscal Year: 2003..The proposed studies will add significantly to our ability to practice evidence-based medicine regarding the evaluation and management of hypertensive children. ..
