Jessica A Shafer
Affiliation: Baylor College of Medicine
- Antigen-specific cytotoxic T lymphocytes can target chemoresistant side-population tumor cells in Hodgkin lymphomaJessica A Shafer
Center for Cell and Gene Therapy, Department of Pediatrics, Baylor College of Medicine, The Methodist Hospital and Texas Children s Cancer Center, Houston, TX 77030, USA
Leuk Lymphoma 51:870-80. 2010..This study suggests that chemoresistant HL SP cells can be targeted by the immune system, providing a rationale for combined chemotherapy and immunotherapy for the treatment of HL...
- Improving T-cell therapy for relapsed EBV-negative Hodgkin lymphoma by targeting upregulated MAGE-A4Conrad R Cruz
Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, Texas
Clin Cancer Res 17:7058-66. 2011..Furthermore, epigenetic modification by clinically available demethylating agents can enhance MAGE-A4 expression in previously MAGE-negative tumors...
- The histone deacetylase inhibitor entinostat (SNDX-275) induces apoptosis in Hodgkin lymphoma cells and synergizes with Bcl-2 family inhibitorsAdam Jona
Department of Lymphoma and Myeloma, The University of Texas M D Anderson Cancer Center, Houston, USA
Exp Hematol 39:1007-1017.e1. 2011..Based on promising in vitro and in vivo activity of several histone deacetylase inhibitors in Hodgkin lymphoma (HL), we investigated SNDX-275, an oral class 1 isoform-selective histone deacetylase inhibitors in HL-derived cell lines...
- Novel compound enables high-level adenovirus transduction in the absence of an adenovirus-specific receptorChristine M Fouletier-Dilling
Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX 77030, USA
Hum Gene Ther 16:1287-97. 2005..The results suggest a novel and versatile method for achieving high-level transduction using adenovirus...