Peter Saggau

Summary

Affiliation: Baylor College of Medicine
Country: USA

Publications

  1. ncbi request reprint New methods and uses for fast optical scanning
    Peter Saggau
    Department of Neuroscience, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    Curr Opin Neurobiol 16:543-50. 2006
  2. ncbi request reprint Acousto-optic laser scanning for multi-site photo-stimulation of single neurons in vitro
    Bradley E Losavio
    Baylor College of Medicine, Houston, TX, USA
    J Neural Eng 7:045002. 2010
  3. doi request reprint Live neuron morphology automatically reconstructed from multiphoton and confocal imaging data
    Bradley E Losavio
    Department of Neuroscience, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    J Neurophysiol 100:2422-9. 2008
  4. ncbi request reprint High-speed addressable confocal microscopy for functional imaging of cellular activity
    Vivek Bansal
    Baylor College of Medicine, Department of Neuroscience, Houston, Texas 77030, USA
    J Biomed Opt 11:34003. 2006
  5. ncbi request reprint Standing wave total internal reflection fluorescence microscopy to measure the size of nanostructures in living cells
    Olga Gliko
    Department of Otolaryngology Head and Neck Surgery, Baylor College of Medicine, Houston, Texas 77030, USA
    J Biomed Opt 11:064013. 2006
  6. pmc Two-photon microscope for multisite microphotolysis of caged neurotransmitters in acute brain slices
    Bradley E Losavio
    Baylor College of Medicine, Department of Neuroscience, One Baylor Plaza, Houston, Texas 77030, USA
    J Biomed Opt 14:064033. 2009
  7. ncbi request reprint Fast two-dimensional standing-wave total-internal-reflection fluorescence microscopy using acousto-optic deflectors
    Olga Gliko
    Department of Otorhinolaryngology Head and Neck Surgery, Baylor College of Medicine, Houston, TX 77030, USA
    Opt Lett 34:836-8. 2009
  8. pmc Three-dimensional random access multiphoton microscopy for functional imaging of neuronal activity
    Gaddum Duemani Reddy
    Department of Bioengineering, Rice University, 6100 Main Street, Suite 116 Keck Hall, Houston, Texas 77005, USA
    Nat Neurosci 11:713-20. 2008
  9. ncbi request reprint Population code in mouse V1 facilitates readout of natural scenes through increased sparseness
    Emmanouil Froudarakis
    Department of Neuroscience, Baylor College of Medicine, Houston, Texas, USA
    Nat Neurosci 17:851-7. 2014
  10. ncbi request reprint Combining optical imaging and computational modeling to analyze structure and function of living neurons
    Bradley E Losavio
    Dept of Neuroscience, Baylor College of Medicine, Houston, TX 77030, USA
    Conf Proc IEEE Eng Med Biol Soc 1:668-70. 2006

Collaborators

Detail Information

Publications19

  1. ncbi request reprint New methods and uses for fast optical scanning
    Peter Saggau
    Department of Neuroscience, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    Curr Opin Neurobiol 16:543-50. 2006
    ..The number of recent advances in scanning methods indicates their increasing importance in imaging techniques...
  2. ncbi request reprint Acousto-optic laser scanning for multi-site photo-stimulation of single neurons in vitro
    Bradley E Losavio
    Baylor College of Medicine, Houston, TX, USA
    J Neural Eng 7:045002. 2010
    ..Our laser scanning systems can produce the sophisticated spatio-temporal patterns of synaptic input that are necessary to investigate single-neuron dendritic physiology...
  3. doi request reprint Live neuron morphology automatically reconstructed from multiphoton and confocal imaging data
    Bradley E Losavio
    Department of Neuroscience, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    J Neurophysiol 100:2422-9. 2008
    ..In this report, we validate the utility of this procedure by comparing its performance on live neurons and test specimens with other fully and semiautomated reconstruction tools...
  4. ncbi request reprint High-speed addressable confocal microscopy for functional imaging of cellular activity
    Vivek Bansal
    Baylor College of Medicine, Department of Neuroscience, Houston, Texas 77030, USA
    J Biomed Opt 11:34003. 2006
    ..Additionally, we use the system to record intracellular calcium transients at several sites in hippocampal neurons using the fluorescent calcium indicator Oregon Green BAPTA-1...
  5. ncbi request reprint Standing wave total internal reflection fluorescence microscopy to measure the size of nanostructures in living cells
    Olga Gliko
    Department of Otolaryngology Head and Neck Surgery, Baylor College of Medicine, Houston, Texas 77030, USA
    J Biomed Opt 11:064013. 2006
    ..The combination of SWFM with total internal reflection (TIR), referred to as SW-TIRFM, allows additional improvement of axial resolution by selective excitation of fluorescence in a layer of about 100 nm...
  6. pmc Two-photon microscope for multisite microphotolysis of caged neurotransmitters in acute brain slices
    Bradley E Losavio
    Baylor College of Medicine, Department of Neuroscience, One Baylor Plaza, Houston, Texas 77030, USA
    J Biomed Opt 14:064033. 2009
    ..This system enables the study of multisynaptic integration and will assist our understanding of single neuron function and dendritic computation...
  7. ncbi request reprint Fast two-dimensional standing-wave total-internal-reflection fluorescence microscopy using acousto-optic deflectors
    Olga Gliko
    Department of Otorhinolaryngology Head and Neck Surgery, Baylor College of Medicine, Houston, TX 77030, USA
    Opt Lett 34:836-8. 2009
    ..This technique can provide real-time imaging of subresolution structures in live biological specimens near a glass-water interface...
  8. pmc Three-dimensional random access multiphoton microscopy for functional imaging of neuronal activity
    Gaddum Duemani Reddy
    Department of Bioengineering, Rice University, 6100 Main Street, Suite 116 Keck Hall, Houston, Texas 77005, USA
    Nat Neurosci 11:713-20. 2008
    ....
  9. ncbi request reprint Population code in mouse V1 facilitates readout of natural scenes through increased sparseness
    Emmanouil Froudarakis
    Department of Neuroscience, Baylor College of Medicine, Houston, Texas, USA
    Nat Neurosci 17:851-7. 2014
    ..Our results argue for a functional benefit of sparsification that could be a general principle governing the structure of the population activity throughout cortical microcircuits. ..
  10. ncbi request reprint Combining optical imaging and computational modeling to analyze structure and function of living neurons
    Bradley E Losavio
    Dept of Neuroscience, Baylor College of Medicine, Houston, TX 77030, USA
    Conf Proc IEEE Eng Med Biol Soc 1:668-70. 2006
    ....
  11. pmc Multiphoton adaptation of a commercial low-cost confocal microscope for live tissue imaging
    James J Mancuso
    Baylor College of Medicine, Verna and Marrs McLean Department of Biochemistry, One Baylor Plaza, Houston, Texas 77030, USA
    J Biomed Opt 14:034048. 2009
    ..The entire system, including scan mirrors and detector box, remain under the control of the user-friendly Nikon EZ-C1 software without modification...
  12. pmc Compartmentalization of the outer hair cell demonstrated by slow diffusion in the extracisternal space
    Olga Gliko
    Department of Otorhinolaryngology Head and Neck Surgery, Baylor College of Medicine, Houston, Texas, USA
    Biophys J 97:1215-24. 2009
    ..Compared with free solution, the diffusion of 10 kDa dextran was slowed down in both the ECiS and the axial core by a factor of 4.6 and 1.6, respectively...
  13. pmc Three-dimensional mapping of microcircuit correlation structure
    R James Cotton
    Department of Neuroscience, Baylor College of Medicine Houston, TX, USA
    Front Neural Circuits 7:151. 2013
    ..Three-dimensional random access multiphoton imaging with concurrent motion tracking provides a novel, powerful method to characterize the microcircuit activity in vivo. ..
  14. pmc Photometric recording of transmembrane potential in outer hair cells
    Takashi Nakagawa
    Bobby R Alford Department of Otolaryngology Head and Neck Surgery, Baylor College of Medicine, Houston, TX 77030, USA
    J Neural Eng 3:79-86. 2006
    ..Results are consistent with the hypothesis that OHCs exhibit inhomogeneous membrane potentials that vary with position in analogy with the voltage in nerve axons...
  15. pmc Calcium imaging of inner ear hair cells within the cochlear epithelium of mice using two-photon microscopy
    Tao Yuan
    Baylor College of Medicine, The Bobby R Alford Department of Otolaryngology, Head and Neck Surgery, Houston, Texas 77030, USA
    J Biomed Opt 15:016002. 2010
    ..Because the epithelium is left within the cochlea, dissection trauma is minimized and artifactual changes in hair cell physiology are expected to be reduced...
  16. ncbi request reprint Fast functional imaging of single neurons using random-access multiphoton (RAMP) microscopy
    Vijay Iyer
    Department of Neuroscience, One Baylor Plaza, S603, Houston, TX 77030, USA
    J Neurophysiol 95:535-45. 2006
    ..RAMP microscopy thus comprises a versatile tool for investigating correlations of dendritic structure and function with significantly enhanced experimental throughput...
  17. ncbi request reprint Fast three-dimensional laser scanning scheme using acousto-optic deflectors
    Gaddum Duemani Reddy
    Rice University, Department of Bioengineering, Houston, Texas 77005, USA
    J Biomed Opt 10:064038. 2005
    ..When used for this purpose, we demonstrate how this scheme would also inherently compensate for spatial dispersion when ultrafast laser pulses are used in acousto-optic multiphoton microscopy...
  18. ncbi request reprint Facilitation of L-type Ca2+ channels in dendritic spines by activation of beta2 adrenergic receptors
    Tycho M Hoogland
    Department of Neuroscience, Baylor College of Medicine, Houston, Texas 77030, USA
    J Neurosci 24:8416-27. 2004
    ....
  19. ncbi request reprint Compensation of spatial and temporal dispersion for acousto-optic multiphoton laser-scanning microscopy
    Vijay Iyer
    Rice University, Department of Electrical and Computer Engineering, Houston, Texas 77005, USA
    J Biomed Opt 8:460-71. 2003
    ..These developments enable the construction of a 2-D acousto-optic multiphoton laser-scanning microscope system...