RYAN ROCHATSummaryAffiliation: Baylor College of Medicine Location: Houston, USA Publications
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Detail Information
Publications
A novel method combining linkage disequilibrium information and imputed functional knowledge for tagSNP selectionR H Rochat
Division of Biostatistics, Washington University School of Medicine, St Louis, MO 63110, USA
Hum Hered 64:243-9. 2007..Furthermore, WFA consistently included SNPs not selected by function or by LD alone. A literature review of a subset of genes revealed that SNPs selected by WFA were more likely represented in published reports...
A matching algorithm to address imbalances in study populations: application to the National Institute of Neurological Diseases and Stroke Recombinant Tissue Plasminogen Activator acute stroke trialPitchaiah Mandava
Michael E DeBakey VA Medical Center Stroke Program and the Department of Neurology, Baylor College of Medicine, Houston, Texas, USA
Stroke 41:765-70. 2010..To illustrate the approach, we rebalanced the National Institute of Neurological Diseases and Stroke Recombinant Tissue Plasminogen Activator trial, in which the contribution of baseline imbalances continues to be debated...
Seeing the portal in herpes simplex virus type 1 B capsidsR H Rochat
Structural Computational Biology and Molecular Biophysics Program, Baylor College of Medicine, Houston, Texas 77030, USA
J Virol 85:1871-4. 2011..Our map unequivocally resolves the 12-subunit portal situated beneath one of the pentameric vertices, thus removing uncertainty over the location and stoichiometry of the herpesvirus portal...
Practical performance evaluation of a 10k × 10k CCD for electron cryo-microscopyBenjamin E Bammes
Graduate Program in Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, TX 77030, USA
J Struct Biol 175:384-93. 2011..emdatabank.org/)...
Direct electron detection yields cryo-EM reconstructions at resolutions beyond 3/4 Nyquist frequencyBenjamin E Bammes
Graduate Program in Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, TX 77030, USA
J Struct Biol 177:589-601. 2012..We anticipate the unparalleled performance of this digital recording device will dramatically benefit cryo-EM for routine tomographic and single-particle structural determination of biological specimens...
Reconstructing virus structures from nanometer to near-atomic resolutions with cryo-electron microscopy and tomographyJuan Chang
Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA
Adv Exp Med Biol 726:49-90. 2012..Here we present the common techniques used to acquire and process cryo-EM and cryo-ET data and discuss their implications for structural virology both now and in the future...
