Stephen Richards

Summary

Affiliation: Baylor College of Medicine
Country: USA

Publications

  1. ncbi How is the Drosophila research community making use of the genome sequence?
    Stephen Richards
    Human Genome Sequencing Center, Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, TX 77006, USA
    Genome Biol 4:319. 2003
  2. ncbi Comparative genome sequencing of Drosophila pseudoobscura: chromosomal, gene, and cis-element evolution
    Stephen Richards
    Human Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine, Houston Texas 77030, USA
    Genome Res 15:1-18. 2005
  3. ncbi A sequence-level map of chromosomal breakpoints in the MCF-7 breast cancer cell line yields insights into the evolution of a cancer genome
    Oliver A Hampton
    Bioinformatics Research Laboratory, Baylor College of Medicine, Houston, Texas 77030, USA
    Genome Res 19:167-77. 2009
  4. ncbi The genome of the model beetle and pest Tribolium castaneum
    Stephen Richards
    Human Genome Sequencing Center, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA
    Nature 452:949-55. 2008
  5. ncbi The maternal-effect, selfish genetic element Medea is associated with a composite Tc1 transposon
    Marcé D Lorenzen
    United States Department of Agriculture, Grain Marketing and Production Research Center, Agricultural Research Service, Manhattan, KS 66502, USA
    Proc Natl Acad Sci U S A 105:10085-9. 2008
  6. ncbi Widespread lateral gene transfer from intracellular bacteria to multicellular eukaryotes
    Julie C Dunning Hotopp
    Institute for Genomic Research, J Craig Venter Institute, 9712 Medical Center Drive, Rockville, MD 20850, USA
    Science 317:1753-6. 2007
  7. ncbi Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes
    Adam Siepel
    Center for Biomolecular Science and Engineering, University of California, Santa Cruz, Santa Cruz, California 95064, USA
    Genome Res 15:1034-50. 2005
  8. ncbi The DNA sequence of the human X chromosome
    Mark T Ross
    The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK
    Nature 434:325-37. 2005
  9. ncbi Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence
    Susan E Celniker
    Berkeley Drosophila Genome Project, Department of Genome Sciences, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    Genome Biol 3:RESEARCH0079. 2002
  10. ncbi Systematic determination of patterns of gene expression during Drosophila embryogenesis
    Pavel Tomancak
    Howard Hughes Medical Institute, Department of Molecular and Cell Biology, University of California at Berkeley, 539 Life Sciences Addition, Berkeley, CA 94720-3200, USA
    Genome Biol 3:RESEARCH0088. 2002

Detail Information

Publications12

  1. ncbi How is the Drosophila research community making use of the genome sequence?
    Stephen Richards
    Human Genome Sequencing Center, Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, TX 77006, USA
    Genome Biol 4:319. 2003
    ..A report on the 44th Annual Drosophila Research Conference, Chicago, USA, 5-9 March, 2003...
  2. ncbi Comparative genome sequencing of Drosophila pseudoobscura: chromosomal, gene, and cis-element evolution
    Stephen Richards
    Human Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine, Houston Texas 77030, USA
    Genome Res 15:1-18. 2005
    ..Overall, a pattern of repeat-mediated chromosomal rearrangement, and high coadaptation of both male genes and cis-regulatory sequences emerges as important themes of genome divergence between these species of Drosophila...
  3. ncbi A sequence-level map of chromosomal breakpoints in the MCF-7 breast cancer cell line yields insights into the evolution of a cancer genome
    Oliver A Hampton
    Bioinformatics Research Laboratory, Baylor College of Medicine, Houston, Texas 77030, USA
    Genome Res 19:167-77. 2009
    ..We show that knock-down of SULF2 in cell lines causes tumorigenic phenotypes, including increased proliferation, enhanced survival, and increased anchorage-independent growth...
  4. ncbi The genome of the model beetle and pest Tribolium castaneum
    Stephen Richards
    Human Genome Sequencing Center, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA
    Nature 452:949-55. 2008
    ..Systemic RNA interference in T. castaneum functions differently from that in Caenorhabditis elegans, but nevertheless offers similar power for the elucidation of gene function and identification of targets for selective insect control...
  5. ncbi The maternal-effect, selfish genetic element Medea is associated with a composite Tc1 transposon
    Marcé D Lorenzen
    United States Department of Agriculture, Grain Marketing and Production Research Center, Agricultural Research Service, Manhattan, KS 66502, USA
    Proc Natl Acad Sci U S A 105:10085-9. 2008
    ..The Medea system in Tribolium represents an unusual type of intragenomic conflict and could provide a useful vehicle for driving desirable genes into populations...
  6. ncbi Widespread lateral gene transfer from intracellular bacteria to multicellular eukaryotes
    Julie C Dunning Hotopp
    Institute for Genomic Research, J Craig Venter Institute, 9712 Medical Center Drive, Rockville, MD 20850, USA
    Science 317:1753-6. 2007
    ..Therefore, heritable lateral gene transfer occurs into eukaryotic hosts from their prokaryote symbionts, potentially providing a mechanism for acquisition of new genes and functions...
  7. ncbi Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes
    Adam Siepel
    Center for Biomolecular Science and Engineering, University of California, Santa Cruz, Santa Cruz, California 95064, USA
    Genome Res 15:1034-50. 2005
    ..Noncoding HCEs also show strong statistical evidence of an enrichment for RNA secondary structure...
  8. ncbi The DNA sequence of the human X chromosome
    Mark T Ross
    The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK
    Nature 434:325-37. 2005
    ..Of this number, 168 have been explained by mutations in 113 X-linked genes, which in many cases were characterized with the aid of the DNA sequence...
  9. ncbi Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence
    Susan E Celniker
    Berkeley Drosophila Genome Project, Department of Genome Sciences, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    Genome Biol 3:RESEARCH0079. 2002
    ....
  10. ncbi Systematic determination of patterns of gene expression during Drosophila embryogenesis
    Pavel Tomancak
    Howard Hughes Medical Institute, Department of Molecular and Cell Biology, University of California at Berkeley, 539 Life Sciences Addition, Berkeley, CA 94720-3200, USA
    Genome Biol 3:RESEARCH0088. 2002
    ..Systematic analysis of rigorously annotated patterns of gene expression will complement and extend the types of analyses carried out using expression microarrays...
  11. ncbi Polytene chromosomal maps of 11 Drosophila species: the order of genomic scaffolds inferred from genetic and physical maps
    Stephen W Schaeffer
    Department of Biology and Institute of Molecular Evolutionary Genetics, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Genetics 179:1601-55. 2008
    ..Despite the conservation of genes within homologous chromosome arms across species, the karyotypes of these species have changed through the fusion of chromosomal arms followed by subsequent rearrangement events...
  12. ncbi Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences
    Robert L Strausberg
    National Cancer Institute, Bethessda, MD 20892 2580, USA
    Proc Natl Acad Sci U S A 99:16899-903. 2002
    ..All MGC sequences and clones are available without restriction through public databases and clone distribution networks (see http:mgc.nci.nih.gov)...