John Reveille

Summary

Affiliation: Baylor College of Medicine
Country: USA

Publications

  1. ncbi The genetic basis of autoantibody production
    John D Reveille
    Division of Rheumatology and Clinical Immunogenetics, The University of Texas at Houston Health Science Center, 6431 Fannin, MSB 5 270, Houston, TX, 77030, USA
    Autoimmun Rev 5:389-98. 2006
  2. ncbi Economic considerations of the treatment of ankylosing spondylitis
    John D Reveille
    Division of Rheumatology, University of Texas Houston Health Science Center, 77030, USA
    Am J Med Sci 343:371-4. 2012
  3. ncbi Genetics of spondyloarthritis--beyond the MHC
    John D Reveille
    The University of Texas Health Science Center at Houston, MSB 5 270, 6431 Fannin, Houston, TX 77030, USA
    Nat Rev Rheumatol 8:296-304. 2012
  4. ncbi The prevalence of HLA-B27 in the US: data from the US National Health and Nutrition Examination Survey, 2009
    John D Reveille
    Division of Rheumatology, University of Texas Health Science Center at Houston, 6431 Fannin Street, MSB 5 270, Houston, TX 77030, USA
    Arthritis Rheum 64:1407-11. 2012
  5. ncbi Novel multiplex technology for diagnostic characterization of rheumatoid arthritis
    Piyanka E Chandra
    Division of Immunology and Rheumatology, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
    Arthritis Res Ther 13:R102. 2011
  6. ncbi Psychological correlates of self-reported functional limitation in patients with ankylosing spondylitis
    Tamar F Brionez
    Department of Medicine, Division of Rheumatology, University of Texas Houston, 6431 Fannin, Houston, Texas 77030, USA
    Arthritis Res Ther 11:R182. 2009
  7. ncbi Plasma cytokine profiles in systemic sclerosis: associations with autoantibody subsets and clinical manifestations
    Pravitt Gourh
    Division of Rheumatology and Clinical Immunogenetics, Department of Internal Medicine, University of Texas Health Science Center at Houston, 6431 Fannin M S B 5 278, Houston, TX 77030, USA
    Arthritis Res Ther 11:R147. 2009
  8. ncbi ANKH variants associated with ankylosing spondylitis: gender differences
    Hing Wo Tsui
    Toronto Western Research Institute, Toronto, Ontario, Canada
    Arthritis Res Ther 7:R513-25. 2005
  9. ncbi Inflammatory bowel disease serologies in ankylosing spondylitis patients: a pilot study
    Matthew L Mundwiler
    Rockford Orthopedic Associates, 324 Roxbury Rd, Rockford, IL 61107, USA
    Arthritis Res Ther 11:R177. 2009
  10. ncbi Predictors of interstitial lung disease in early systemic sclerosis: a prospective longitudinal study of the GENISOS cohort
    Shervin Assassi
    Division of Rheumatology and Clinical Immunogenetics, University of Texas Houston, 6431 Fannin, Houston, TX 77030, USA
    Arthritis Res Ther 12:R166. 2010

Research Grants

  1. Genetics and Ankylosing Spondylitis (AS) Pathogenesis
    John Reveille; Fiscal Year: 2007
  2. Pre-and Postdoctoral Training in the Rheumatic Diseases
    John Reveille; Fiscal Year: 2007
  3. Spondyloarthritis 2006; The Unmet Needs
    John Reveille; Fiscal Year: 2006
  4. FAMILY STUDIES OF THE GENETICS OF ANKYLOSING SPONDYLITIS
    John Reveille; Fiscal Year: 2003

Detail Information

Publications99

  1. ncbi The genetic basis of autoantibody production
    John D Reveille
    Division of Rheumatology and Clinical Immunogenetics, The University of Texas at Houston Health Science Center, 6431 Fannin, MSB 5 270, Houston, TX, 77030, USA
    Autoimmun Rev 5:389-98. 2006
    ..These novel associations offer new clues not only to pathogenesis but also to potential therapeutic targets...
  2. ncbi Economic considerations of the treatment of ankylosing spondylitis
    John D Reveille
    Division of Rheumatology, University of Texas Houston Health Science Center, 77030, USA
    Am J Med Sci 343:371-4. 2012
    ..No studies have examined differences in patient outcomes based on subspecialty care. Establishing an evidence base for these questions would help inform policy decisions to design the most cost-effective measures to treat AS...
  3. ncbi Genetics of spondyloarthritis--beyond the MHC
    John D Reveille
    The University of Texas Health Science Center at Houston, MSB 5 270, 6431 Fannin, Houston, TX 77030, USA
    Nat Rev Rheumatol 8:296-304. 2012
    ..Thus, AS, psoriasis and IBD seem to share similar pathogenic mechanisms of aberrant intracellular antigen processing or elimination of intracellular bacteria and cytokine production, especially in the IL-17-IL-23 pathway...
  4. ncbi The prevalence of HLA-B27 in the US: data from the US National Health and Nutrition Examination Survey, 2009
    John D Reveille
    Division of Rheumatology, University of Texas Health Science Center at Houston, 6431 Fannin Street, MSB 5 270, Houston, TX 77030, USA
    Arthritis Rheum 64:1407-11. 2012
    ....
  5. ncbi Novel multiplex technology for diagnostic characterization of rheumatoid arthritis
    Piyanka E Chandra
    Division of Immunology and Rheumatology, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
    Arthritis Res Ther 13:R102. 2011
    ..The aim of this study was to develop a clinical-grade, automated, multiplex system for the differential diagnosis and molecular stratification of rheumatoid arthritis (RA)...
  6. ncbi Psychological correlates of self-reported functional limitation in patients with ankylosing spondylitis
    Tamar F Brionez
    Department of Medicine, Division of Rheumatology, University of Texas Houston, 6431 Fannin, Houston, Texas 77030, USA
    Arthritis Res Ther 11:R182. 2009
    ..The purpose of this study was to investigate the role of psychological variables in self-reported functional limitation in patients with AS, while controlling for demographic and medical variables...
  7. ncbi Plasma cytokine profiles in systemic sclerosis: associations with autoantibody subsets and clinical manifestations
    Pravitt Gourh
    Division of Rheumatology and Clinical Immunogenetics, Department of Internal Medicine, University of Texas Health Science Center at Houston, 6431 Fannin M S B 5 278, Houston, TX 77030, USA
    Arthritis Res Ther 11:R147. 2009
    ..The current report sought to determine whether plasma cytokine profiles differ in SSc patients grouped according to these SSc-associated autoantibody subsets...
  8. ncbi ANKH variants associated with ankylosing spondylitis: gender differences
    Hing Wo Tsui
    Toronto Western Research Institute, Toronto, Ontario, Canada
    Arthritis Res Ther 7:R513-25. 2005
    ..These findings support the concept that ANKH plays a role in genetic susceptibility to AS and reveals a gender-genotype specificity in this interaction...
  9. ncbi Inflammatory bowel disease serologies in ankylosing spondylitis patients: a pilot study
    Matthew L Mundwiler
    Rockford Orthopedic Associates, 324 Roxbury Rd, Rockford, IL 61107, USA
    Arthritis Res Ther 11:R177. 2009
    ..Because of the overlap between the two conditions, a pilot study was designed to compare the frequency of these antibodies in AS patients compared to normal controls...
  10. ncbi Predictors of interstitial lung disease in early systemic sclerosis: a prospective longitudinal study of the GENISOS cohort
    Shervin Assassi
    Division of Rheumatology and Clinical Immunogenetics, University of Texas Houston, 6431 Fannin, Houston, TX 77030, USA
    Arthritis Res Ther 12:R166. 2010
    ....
  11. ncbi Update on the treatment of systemic lupus erythematosus
    Ana M Arango
    Division of Rheumatology, The University of Texas Health Science Center at Houston, Houston, TX, USA
    Womens Health (Lond Engl) 2:605-16. 2006
    ....
  12. ncbi Spondyloarthritis: update on pathogenesis and management
    John D Reveille
    Division of Rheumatology, Department of Internal Medicine, The University of Texas Houston Health Science Center, USA
    Am J Med 118:592-603. 2005
    ..Their high cost and considerable side effect profile, however, have necessitated the establishment of guidelines for their use in these diseases in order to target the patient in whom they are likely to have the most benefit...
  13. ncbi Infection and musculoskeletal conditions: Rheumatologic complications of HIV infection
    John D Reveille
    The University of Texas Houston Health Science Center, MSB 5 270, 6431 Fannin, Houston, TX77030, USA
    Best Pract Res Clin Rheumatol 20:1159-79. 2006
    ....
  14. ncbi Recent studies on the genetic basis of ankylosing spondylitis
    John D Reveille
    Division of Rheumatology and Clinical Immunogenetics, The University of Texas Health Science Center at Houston, 6431 Fannin, MSB 5 270, Houston, TX 77030, USA
    Curr Rheumatol Rep 11:340-8. 2009
    ..Tremendous progress has been made with respect to understanding the genetic basis of AS. The identification of new genes-ARTS1, IL23R, and IL1A-substantiate that susceptibility to AS is also determined by genes outside the MHC...
  15. ncbi Subtypes of HLA-B27: history and implications in the pathogenesis of ankylosing spondylitis
    John D Reveille
    Division of Rheumatology and Clinical Immunogenetics, University of Texas Health Science Center, Houston, TX 77026, USA
    Adv Exp Med Biol 649:159-76. 2009
    ..Studies from different parts of the world reveal differences in the population distribution...
  16. ncbi The genetic basis of ankylosing spondylitis
    John D Reveille
    Division of Rheumatology and Clinical Immunogenetics, University of Texas Health Science Center at Houston, Houston, Texas 77030, USA
    Curr Opin Rheumatol 18:332-41. 2006
    ..This review is aimed at summarizing the status of major histocompatibility complex and non-major histocompatibility complex genes in ankylosing spondylitis susceptibility, and suggests areas for future studies...
  17. ncbi Major histocompatibility genes and ankylosing spondylitis
    John D Reveille
    Division of Rheumatology, The University of Texas Health Science Center at Houston, 6431, Fannin, TX 77030, USA
    Best Pract Res Clin Rheumatol 20:601-9. 2006
    ....
  18. ncbi Predictive value of autoantibodies for activity of systemic lupus erythematosus
    J D Reveille
    Division of Rheumatology, The University of Texas, Houston Health Science Center at Houston, Houston, TX 77030, USA
    Lupus 13:290-7. 2004
    ..New technologies using proteomic determinations show promise as aids in the search for more reliable and feasible autoantibody determinations of disease activity in SLE...
  19. ncbi The clinical relevance of autoantibodies in scleroderma
    Khanh T Ho
    Division of Rheumatology and Clinical Immunogenetics and General Medicine, The University of Texas Houston Health Science Center UTH HSC, Houston, Texas, USA
    Arthritis Res Ther 5:80-93. 2003
    ..Limited reports of other autoantibodies (anti-Ku, antiphospholipid) have not established them as being clinically useful in following patients with SSc...
  20. ncbi The changing spectrum of rheumatic disease in human immunodeficiency virus infection
    J D Reveille
    Department of Medicine Division of Rheumatology and Clinical Immunogenetics, The University of Texas Houston Health Science Center UTH HSC, Houston, TX 77030, USA
    Semin Arthritis Rheum 30:147-66. 2000
    ....
  21. ncbi Epidemiology of spondyloarthritis in North America
    John D Reveille
    Division of Rheumatology, The University of Texas Health Science Center at Houston, Houston, Texas 77030, USA
    Am J Med Sci 341:284-6. 2011
    ....
  22. ncbi Evidence-based guidelines for the use of immunologic tests: anticentromere, Scl-70, and nucleolar antibodies
    John D Reveille
    University of Texas Health Science Center, Houston 77030, USA
    Arthritis Rheum 49:399-412. 2003
  23. ncbi Ethnicity and race and systemic sclerosis: how it affects susceptibility, severity, antibody genetics, and clinical manifestations
    John D Reveille
    Division of Rheumatology and Clinical Immunogenetics, The University of Texas Health Sciences Center at Houston, 77030, USA
    Curr Rheumatol Rep 5:160-7. 2003
    ..Although these facts do not entirely rule out socioeconomic factors associated with ethnicity, nevertheless ethnicity has an important impact on the pathogenesis of systemic sclerosis, perhaps because of genetic factors...
  24. ncbi The genetic basis of spondyloarthritis
    John D Reveille
    The University of Texas Houston Health Science Center, MSB 5 270, 6431 Fannin, Houston, TX 77030, USA
    Ann Rheum Dis 70:i44-50. 2011
    ..In IBD, genes important in the innate immune response (NOD2), autophagy (ATG6L1) and regulation of the IL-23 pathway (IL-23R) play a role in disease susceptibility...
  25. ncbi Epidemiology of ankylosing spondylitis: IGAS 2009
    John D Reveille
    Division of Rheumatology and Clinical Immunogenetics, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA
    J Rheumatol 37:2624-5. 2010
    ..This chip will type 200,000 SNP selected from the most strongly associated variants identified in genome-wide association studies of inflammatory diseases, including inflammatory bowel disease, psoriasis, and ankylosing spondylitis...
  26. ncbi The genetic basis of spondyloarthritis
    John D Reveille
    Division of Rheumatology, Department of Internal Medicine, The University of Texas Houston Health Science Center at Houston, MSB 5 270, 6431 Fannin, Houston, TX 77030, USA
    Curr Rheumatol Rep 6:117-25. 2004
    ....
  27. ncbi Association of the C8orf13-BLK region with systemic sclerosis in North-American and European populations
    Pravitt Gourh
    Division of Rheumatology and Clinical Immunogenetics, Department of Internal Medicine, University of Texas Health Science Center at Houston UTHSC H, Houston, TX 77030, USA
    J Autoimmun 34:155-62. 2010
    ..The current report sought to determine if polymorphisms in the C8orf13-BLK region (chromosome 8p23.1-B lymphoid tyrosine kinase), which is associated with SLE, are associated also with SSc...
  28. ncbi HLA-DPB1 and DPB2 are genetic loci for systemic sclerosis: a genome-wide association study in Koreans with replication in North Americans
    Xiaodong Zhou
    University of Texas Health Science Center at Houston, Houston, TX, USA
    Arthritis Rheum 60:3807-14. 2009
    ..To identify systemic sclerosis (SSc) susceptibility loci via a genome-wide association study...
  29. ncbi The contribution of genes outside the major histocompatibility complex to susceptibility to ankylosing spondylitis
    Tamar F Brionez
    Division of Rheumatology and Clinical Immunogenetics, The University of Texas Health Science Center at Houston, Houston, Texas 77030, USA
    Curr Opin Rheumatol 20:384-91. 2008
    ..Recent data have presented several new nonmajor histocompatibility complex genes in predisposition to ankylosing spondylitis, which will be summarized here...
  30. ncbi Pulmonary involvement in systemic sclerosis: associations with genetic, serologic, sociodemographic, and behavioral factors
    Terry A McNearney
    Division of Rheumatology, University of Texas Medical Branch at Galveston, Galveston, Texas 77555 1165, USA
    Arthritis Rheum 57:318-26. 2007
    ..To determine the relative contributions of genetic, clinical, serologic, sociodemographic, and behavioral/psychological variables to early pulmonary involvement in the Genetics versus Environment in Scleroderma Outcome Study cohort...
  31. ncbi Systemic lupus erythematosus in a multiethnic US cohort, XXXVII: association of lymphopenia with clinical manifestations, serologic abnormalities, disease activity, and damage accrual
    Luis M Vila
    Division of Rheumatology, Department of Internal Medicine, University of Puerto Rico, Medical Sciences Campus, San Juan, Puerto Rico
    Arthritis Rheum 55:799-806. 2006
    ..To determine if lymphopenia is associated with clinical/immunologic manifestations, disease activity, and disease damage in systemic lupus erythematosus (SLE)...
  32. ncbi Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci
    John D Reveille
    University of Texas Health Science Center at Houston, USA
    Nat Genet 42:123-7. 2010
    ..3 x 10(-12)). This study reports four genetic loci associated with ankylosing spondylitis risk and identifies a major role for the interleukin (IL)-23 and IL-1 cytokine pathways in disease susceptibility...
  33. ncbi Trust in physicians and elements of the medical interaction in patients with rheumatoid arthritis and systemic lupus erythematosus
    Javier P Berrios-Rivera
    Baylor College of Medicine and Michael E. DeBakey Veterans Affairs Medical Center, 2002 Holcombe Boulevard, Houston, TX 77030, USA
    Arthritis Rheum 55:385-93. 2006
    ..Furthermore, patients appear to be more willing to disclose concerns when physicians use a patient-centered communication style...
  34. ncbi Treatment adherence in patients with rheumatoid arthritis and systemic lupus erythematosus
    Araceli Garcia-Gonzalez
    University of Texas M D Anderson Cancer Center, Anderson 1400 Holcombe Boulevard Unit 437, Houston, TX 77030, USA
    Clin Rheumatol 27:883-9. 2008
    ..These appear to be more prevalent in African Americans and Hispanics than Whites; the impact of decreased adherence on outcomes could be significant and should be considered when treating patients with RA and SLE...
  35. ncbi Clinical, immunologic, and genetic features of familial systemic sclerosis
    Shervin Assassi
    University of Texas Health Science Center, Houston, TX 77030, USA
    Arthritis Rheum 56:2031-7. 2007
    ....
  36. ncbi Rheumatic manifestations associated with HIV in the highly active antiretroviral therapy era
    Binh Y Nguyen
    Division of Rheumatology and Clinical Immunogenetics, The University of Texas Health Science Center at Houston, Houston, Texas, USA
    Curr Opin Rheumatol 21:404-10. 2009
    ..To evaluate the rheumatic manifestations associated with HIV infection in the highly active antiretroviral therapy (HAART) era...
  37. ncbi Presence of the human leukocyte antigen class II gene DRB1*1101 predicts interferon gamma levels and disease recurrence in melanoma patients
    Jeffrey E Lee
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Ann Surg Oncol 9:587-93. 2002
    ..Human leukocyte antigen (HLA) class II genes can regulate cytokine production; we investigated whether these genes would predict IFN-gamma levels and recurrence in melanoma patients...
  38. ncbi Association of novel polymorphisms with the expression of SPARC in normal fibroblasts and with susceptibility to scleroderma
    Xiaodong Zhou
    Division of Rheumatology and Clinical Immunogenetics, University of Texas Houston Medical School, 6431 Fannin, MSB 5 270, Houston, TX 77030, USA
    Arthritis Rheum 46:2990-9. 2002
    ..SPARC (secreted protein, acidic and rich in cysteine) regulates the deposition or assembly of ECM components. The aim of this study was to investigate the role of SPARC in SSc susceptibility by functional and genetic association studies...
  39. ncbi Major histocompatibility complex (MHC) class II alleles, haplotypes and epitopes which confer susceptibility or protection in systemic sclerosis: analyses in 1300 Caucasian, African-American and Hispanic cases and 1000 controls
    Frank C Arnett
    Division of Rheumatology, Department of Internal Medicine, The University of Texas Health Science Center at Houston UTHSC H, 6431 Fannin Street, MSB 5 270, Houston, TX 77030, USA
    Ann Rheum Dis 69:822-7. 2010
    ....
  40. ncbi Clinical and genetic factors predictive of mortality in early systemic sclerosis
    Shervin Assassi
    University of Texas Health Science Center at Houston, Houston, TX 77030, USA
    Arthritis Rheum 61:1403-11. 2009
    ..To investigate the clinical and genetic variables at initial presentation that predict survival in the Genetics versus Environment in Scleroderma Outcome Study (GENISOS) cohort...
  41. ncbi Association of TNFSF4 (OX40L) polymorphisms with susceptibility to systemic sclerosis
    Pravitt Gourh
    Division of Rheumatology and Clinical Immunogenetics, MSB 5 278, Houston, Texas 77030, USA
    Ann Rheum Dis 69:550-5. 2010
    ..Accordingly, the aim of the current study was to investigate the possible association of the TNFSF4 gene region with systemic sclerosis (SSc), an autoimmune disease that leads to the development of cutaneous and visceral fibrosis...
  42. ncbi Systemic sclerosis and lupus: points in an interferon-mediated continuum
    Shervin Assassi
    University of Texas Health Science Center, Houston, TX, USA
    Arthritis Rheum 62:589-98. 2010
    ..To investigate peripheral blood (PB) cell transcript profiles of systemic sclerosis (SSc) and its subtypes in direct comparison with systemic lupus erythematosus (SLE)...
  43. ncbi Whole-blood gene expression profiling in ankylosing spondylitis shows upregulation of toll-like receptor 4 and 5
    Shervin Assassi
    Department of Medicine, Division of Rheumatology, University of Texas Health Science Center, Houston, TX 77030, USA
    J Rheumatol 38:87-98. 2011
    ..to identify differentially expressed genes in peripheral blood cells (PBC) of patients with ankylosing spondylitis (AS) relative to healthy controls and controls with systemic inflammation...
  44. ncbi Polymorphisms in TBX21 and STAT4 increase the risk of systemic sclerosis: evidence of possible gene-gene interaction and alterations in Th1/Th2 cytokines
    Pravitt Gourh
    University of Texas Health Science Center at Houston, Houston, TX 77030, USA
    Arthritis Rheum 60:3794-806. 2009
    ....
  45. ncbi Genetic studies in the rheumatic diseases: present status and implications for the future
    John D Reveille
    Division of Rheumatology and Clinical Immunogenetics, University of Texas Houston Health Science Ctr, Houston, Texas 77030, USA
    J Rheumatol Suppl 72:10-3. 2005
    ....
  46. ncbi Classification analysis of the transcriptosome of nonlesional cultured dermal fibroblasts from systemic sclerosis patients with early disease
    Filemon K Tan
    Department of Internal Medicine, University of Texas at Houston Medical School, 77030, USA
    Arthritis Rheum 52:865-76. 2005
    ....
  47. ncbi Association of interleukin 23 receptor polymorphisms with anti-topoisomerase-I positivity and pulmonary hypertension in systemic sclerosis
    Sandeep K Agarwal
    Division of Rheumatology and Clinical Immunogenetics, Department of Internal Medicine, University of Texas Health Science Center at Houston, Texas 77030, USA
    J Rheumatol 36:2715-23. 2009
    ..We investigated the possible association of IL23R with systemic sclerosis (SSc), an autoimmune disease that leads to the development of cutaneous and visceral fibrosis...
  48. ncbi The genetics of scleroderma (systemic sclerosis)
    Sandeep K Agarwal
    Division of Rheumatology and Clinical Immunogenetics, Department of Internal Medicine, The University of Texas Health Science Center at Houston, Houston, Texas 77030, USA
    Curr Opin Rheumatol 22:133-8. 2010
    ..To determine the advances made in the genetics of scleroderma in candidate gene association studies...
  49. ncbi Polymorphisms of endothelial nitric oxide synthase and angiotensin-converting enzyme in systemic sclerosis
    Shervin Assassi
    Division of Rheumatology and Clinical Immunogenetics, University of Texas Health Science Center at Houston, TX 77030, USA
    Am J Med 118:907-11. 2005
  50. ncbi Changing spectrum of the diffuse infiltrative lymphocytosis syndrome
    Dhiman Basu
    The University of Texas Health Science Center at Houston, 77030, USA
    Arthritis Rheum 55:466-72. 2006
    ....
  51. ncbi Therapy insight: the changing spectrum of rheumatic disease in HIV infection
    Rashmi M Maganti
    University of Texas Health Science Center at Houston, TX 77030, USA
    Nat Clin Pract Rheumatol 4:428-38. 2008
    ..Complications such as metabolic abnormalities, osteoporosis, and immune restoration inflammatory syndrome have emerged...
  52. ncbi Perceived functioning has ethnic-specific associations in systemic sclerosis: another dimension of personalized medicine
    Terry A McNearney
    Department of Internal Medicine, University of Texas Medical Branch at Galveston, Galveston, Texas 77555 1165, USA
    J Rheumatol 36:2724-32. 2009
    ..To measure self-reported physical and mental functioning and associated clinical features at study entry in 3 ethnic groups with systemic sclerosis (SSc)...
  53. ncbi Nonmyeloablative stem cell transplant in a patient with advanced systemic sclerosis and systemic lupus erythematosus
    Ola Khorshid
    Division of Blood and Marrow Transplantation, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    J Rheumatol 31:2513-6. 2004
    ..We describe a patient with both diffuse cutaneous SSc and systemic lupus erythematosus who showed mixed chimerism 29 months after undergoing nonmyeloablative stem cell transplant. She experienced remission of both diseases...
  54. ncbi Novel sequence feature variant type analysis of the HLA genetic association in systemic sclerosis
    David R Karp
    Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX 75390 8884, USA
    Hum Mol Genet 19:707-19. 2010
    ....
  55. ncbi Psychological correlates of self-reported disease activity in ankylosing spondylitis
    Tamar F Brionez
    Department of Medicine, Division of Rheumatology, University of Texas Health Science Center at Houston, Houston, Texas 77030, USA
    J Rheumatol 37:829-34. 2010
    ..To investigate the role of psychological variables in self-reported disease activity in patients with ankylosing spondylitis (AS), while controlling for demographic and medical variables...
  56. ncbi Anti-tumor necrosis factor agents for rheumatoid arthritis in the setting of chronic hepatitis C infection
    Frank A Parke
    The University of Texas-Houston Health Science Center, Houston, TX 77030, USA
    Arthritis Rheum 51:800-4. 2004
    ..Therefore, this approach should be further evaluated prospectively for longterm safety...
  57. ncbi Anti-scl-70
    Dhiman Basu
    Division of Rheumatology and Clinical Immunogenetics, The University of Texas-Houston Health Science Center, 77030, USA
    Autoimmunity 38:65-72. 2005
    ....
  58. ncbi Are there gender differences in severity of ankylosing spondylitis? Results from the PSOAS cohort
    Wonuk Lee
    Division of Rheumatology, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Ann Rheum Dis 66:633-8. 2007
    ....
  59. ncbi Autoantibodies in systemic sclerosis and fibrosing syndromes: clinical indications and relevance
    Eduardo J Cepeda
    Division of Rheumatology, The University of Texas-Houston Health Science Center at Houston, 6431 Fannin, Houston, TX 77030, USA
    Curr Opin Rheumatol 16:723-32. 2004
    ..When used appropriately, they can be a useful instrument in the management of scleroderma...
  60. ncbi The genetic basis of spondyloarthritis: SPARTAN/IGAS 2009
    David M Evans
    University of Bristol, Bristol, UK
    J Rheumatol 37:2626-31. 2010
    ..Summaries of those discussions are presented...
  61. ncbi Human immunodeficiency virus-associated polymyositis: a longitudinal study of outcome
    Randall W Johnson
    University of Texas-Houston Health Science Center, Houston 77030, USA
    Arthritis Rheum 49:172-8. 2003
    ..CONCLUSION: HIV-associated myositis occurs at any stage of HIV infection, has a relatively good prognosis, responds well to immunosuppressive therapy, and has little evidence of adverse outcome on the HIV infection...
  62. ncbi Spondyloarthritis: clinical suspicion, diagnosis, and sports
    Brock E Harper
    The University of Texas Health Science Center at Houston, Division of Rheumatology, Houston, TX 77030, USA
    Curr Sports Med Rep 8:29-34. 2009
    ..Sports also pose a risk to patients with SpA as these patients are at high risk of spinal fracture and spinal cord injury...
  63. ncbi Systemic lupus erythematosus in three ethnic groups. XIX. Natural history of the accrual of the American College of Rheumatology criteria prior to the occurrence of criteria diagnosis
    Graciela S Alarcon
    Schools of Medicine and Public Health, The University of Alabama at Birmingham, AL 35294, USA
    Arthritis Rheum 51:609-15. 2004
    ..To determine how the American College of Rheumatology (ACR) criteria for the classification of systemic lupus erythematosus (SLE) accrue in a multiethnic cohort of SLE patients...
  64. ncbi Lack of linkage of IL1RN genotypes with ankylosing spondylitis susceptibility
    Li Jin
    University of Cincinnati Cincinnati, OH, USA
    Arthritis Rheum 50:3047-8. 2004
  65. ncbi Genome-wide association study for regions of systemic sclerosis susceptibility in a Choctaw Indian population with high disease prevalence
    Xiaodong Zhou
    University of Texas-Houston Medical School
    Arthritis Rheum 48:2585-92. 2003
    ....
  66. ncbi A locus on chromosome 9p predisposes to a specific disease manifestation, acute anterior uveitis, in ankylosing spondylitis, a genetically complex, multisystem, inflammatory disease
    Tammy M Martin
    Casey Eye Institute, CE RES, Oregon Health and Science University, 3375 SW Terwilliger Boulevard, Portland, OR 97239, USA
    Arthritis Rheum 52:269-74. 2005
    ..We sought to determine whether a unique genetic region could be implicated in a specific manifestation-AAU-of a multisystem, inflammatory, genetically complex disease, AS...
  67. ncbi Systemic lupus erythematosus in three ethnic groups. XI. Sources of discrepancy in perception of disease activity: a comparison of physician and patient visual analog scale scores
    Graciela S Alarcon
    Schools of Medicine and Public Health, University of Alabama at Birmingham, 35294, USA
    Arthritis Rheum 47:408-13. 2002
    ..To compare patient's and physician's assessment of disease activity in a multiethnic (Hispanic, African American, and Caucasian) cohort of systemic lupus erythematosus (SLE) patients...
  68. ncbi Genetic studies in familial ankylosing spondylitis susceptibility
    Ge Zhang
    Center for Genome Information, University of Cincinnati, Cincinnati, Ohio 45267-0056, USA
    Arthritis Rheum 50:2246-54. 2004
    ..33 cM (P = 0.014); this was confirmed by subsequent fine mapping studies. CONCLUSION: Thus, this genome-wide scan implicates, in addition to the MHC, regions outside the MHC in AS susceptibility, especially on chromosomes 6q and 11q...
  69. ncbi Time to renal disease and end-stage renal disease in PROFILE: a multiethnic lupus cohort
    Graciela S Alarcon
    Division of Clinical Immunology and Rheumatology, Department of Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
    PLoS Med 3:e396. 2006
    ..The purpose of this study was to determine the factors predicting the development of renal involvement and its progression to ESRD in a multi-ethnic SLE cohort (PROFILE)...
  70. ncbi The molecular basis of complete complement C4A and C4B deficiencies in a systemic lupus erythematosus patient with homozygous C4A and C4B mutant genes
    Kristi L Rupert
    Children s Research Institute, Department of Pediatrics and Ohio State Biochemistry Program, Ohio State University, Columbus, OH 43205, USA
    J Immunol 169:1570-8. 2002
    ..Hence, complete C4 deficiency is one of the most penetrant genetic risk factors for human systemic lupus erythematosus...
  71. ncbi Editorial comment: HIV-1 infection and the rheumatic diseases--new issues, new challenges, same old disparities
    John D Reveille
    AIDS Read 14:178-9. 2004
  72. ncbi Systemic lupus erythematosus in three ethnic groups. XIV. Poverty, wealth, and their influence on disease activity
    Graciela S Alarcon
    The University of Alabama at Birmingham, AL 35249, USA
    Arthritis Rheum 51:73-7. 2004
    ....
  73. ncbi Novel genetic markers in the 5'-flanking region of ANKH are associated with ankylosing spondylitis
    Florence W L Tsui
    Toronto Western Research Institute and University of Toronto, Toronto, Ontario, Canada
    Arthritis Rheum 48:791-7. 2003
    ..To use a candidate gene approach for the identification of genetic markers that are significantly linked to and associated with ankylosing spondylitis (AS)...
  74. ncbi High-throughput single-nucleotide polymorphism analysis of the IL1RN locus in patients with ankylosing spondylitis by matrix-assisted laser desorption ionization-time-of-flight mass spectrometry
    Walter P Maksymowych
    University of Alberta, Edmonton, Alberta, Canada
    Arthritis Rheum 48:2011-8. 2003
    ....
  75. ncbi Systemic lupus erythematosus in a multiethnic cohort (LUMINA): XXIX. Elevation of erythrocyte sedimentation rate is associated with disease activity and damage accrual
    Luis M Vila
    Division of Rheumatology, University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico
    J Rheumatol 32:2150-5. 2005
    ..To determine if different categories of erythrocyte sedimentation rate (ESR) elevation are associated with disease activity and/or damage in systemic lupus erythematosus (SLE)...
  76. ncbi Immunogenetic risk and protective factors for the idiopathic inflammatory myopathies: distinct HLA-A, -B, -Cw, -DRB1 and -DQA1 allelic profiles and motifs define clinicopathologic groups in caucasians
    Terrance P O'Hanlon
    National Institute of Environmental Health Sciences, Rockville, MD 20892 0958, USA
    Medicine (Baltimore) 84:338-49. 2005
    ..These variations in associated HLA polymorphisms may reflect responses to unique environmental triggers resulting in the tissue pathospecificity and distinct clinicopathologic syndromes of the IIM...
  77. ncbi Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part I
    Charles G Helmick
    CDC, Atlanta, Georgia 30341 3717, USA
    Arthritis Rheum 58:15-25. 2008
    ..A companion article (part II) addresses additional conditions...
  78. ncbi Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants
    Paul R Burton
    Genetic Epidemiology Group, Department of Health Sciences, University of Leicester, Adrian Building, University Road, Leicester LE1 7RH, UK
    Nat Genet 39:1329-37. 2007
    ....
  79. ncbi Using the Short Form 6D, as an overall measure of health, to predict damage accrual and mortality in patients with systemic lupus erythematosus: XLVII, results from a multiethnic US cohort
    Mónica Fernández
    University of Alabama at Birmingham, Alabama, USA
    Arthritis Rheum 57:986-92. 2007
    ....
  80. ncbi The impact of increased body mass index on systemic lupus erythematosus: data from LUMINA, a multiethnic cohort (LUMINA XLVI) [corrected]
    Sumapa Chaiamnuay
    Department of Medicine, Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, Alabama, USA
    J Clin Rheumatol 13:128-33. 2007
    ....
  81. ncbi Association of a TNAP haplotype with ankylosing spondylitis
    Hing Wo Tsui
    Toronto Western Research Institute, Toronto, Ontario, Canada
    Arthritis Rheum 56:234-43. 2007
    ..To use a candidate gene approach to the identification of genetic markers that are significantly associated with ankylosing spondylitis (AS)...
  82. ncbi A multiethnic, multicenter cohort of patients with systemic lupus erythematosus (SLE) as a model for the study of ethnic disparities in SLE
    Mónica Fernández
    The University of Alabama at Birmingham, AL, USA
    Arthritis Rheum 57:576-84. 2007
    ....
  83. ncbi Effect of hydroxychloroquine on the survival of patients with systemic lupus erythematosus: data from LUMINA, a multiethnic US cohort (LUMINA L)
    Graciela S Alarcon
    Department of Medicine Division of Clinical Immunology and Rheumatology, School of Medicine, The University of Alabama at Birmingham, Alabama 35294 3408, USA
    Ann Rheum Dis 66:1168-72. 2007
    ..A study was undertaken to determine whether hydroxychloroquine also exerts a protective effect on survival...
  84. ncbi African-American and Hispanic ethnicities, renal involvement and obesity predispose to hypertension in systemic lupus erythematosus: results from LUMINA, a multiethnic cohort (LUMINAXLV)
    Sumapa Chaiamnuay
    University of Alabama at Birmingham, Birmingham, Alabama, USA
    Ann Rheum Dis 66:618-22. 2007
    ..To examine the predictors of the occurrence of hypertension in a large multiethnic US cohort...
  85. ncbi Genetic variation in the CRP promoter: association with systemic lupus erythematosus
    Jeffrey C Edberg
    Division of Clinical Immunology and Rheumatology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294 2182, USA
    Hum Mol Genet 17:1147-55. 2008
    ..These data demonstrate that rs3093061 at the -707 site within the CRP gene is an SLE susceptibility locus...
  86. ncbi Klinefelter's syndrome (47,XXY) in male systemic lupus erythematosus patients: support for the notion of a gene-dose effect from the X chromosome
    R Hal Scofield
    Oklahoma Medical Research Foundation, University of Oklahoma Health Sciences Center, and Oklahoma City VAMC, Oklahoma City, OK 73104, USA
    Arthritis Rheum 58:2511-7. 2008
    ..The present study was undertaken to investigate the prevalence of Klinefelter's syndrome in a large population of patients with SLE...
  87. ncbi HLA polymorphisms in African Americans with idiopathic inflammatory myopathy: allelic profiles distinguish patients with different clinical phenotypes and myositis autoantibodies
    Terrance P O'Hanlon
    National Institute of Environmental Health Sciences, Bethesda, Maryland 20892, USA
    Arthritis Rheum 54:3670-81. 2006
    ..To investigate possible associations of HLA polymorphisms with idiopathic inflammatory myopathy (IIM) in African Americans, and to compare this with HLA associations in European American IIM patients with IIM...
  88. ncbi Immunogenetic risk and protective factors for the idiopathic inflammatory myopathies: distinct HLA-A, -B, -Cw, -DRB1, and -DQA1 allelic profiles distinguish European American patients with different myositis autoantibodies
    Terrance P O'Hanlon
    National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    Medicine (Baltimore) 85:111-27. 2006
    ....
  89. ncbi Systemic lupus erythematosus in a multiethnic US cohort: XXXIV. Deficient mannose-binding lectin exon 1 polymorphisms are associated with cerebrovascular but not with other arterial thrombotic events
    Jaime Calvo-Alen
    University of Alabama at Birmingham, USA
    Arthritis Rheum 54:1940-5. 2006
    ..To study the association between deficient mannose-binding lectin (MBL) genotypes and arterial thrombotic events in systemic lupus erythematosus (SLE)...
  90. ncbi Systemic lupus erythematosus in a multiethnic US cohort. XXXIII. Clinical [corrected] features, course, and outcome in patients with late-onset disease
    Ana M Bertoli
    University of Alabama at Birmingham School of Medicine, USA
    Arthritis Rheum 54:1580-7. 2006
    ..These findings probably reflect the contribution exerted by other comorbid conditions in the overall impact of lupus in these patients...
  91. ncbi Identification of HLA-DQalpha and -DRbeta residues associated with susceptibility and protection to epithelial ovarian cancer
    Dimitri S Monos
    Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Hum Immunol 66:554-62. 2005
    ....
  92. ncbi Systemic lupus erythematosus in a multiethnic US cohort: XLIII. The significance of thrombocytopenia as a prognostic factor
    Mónica Fernández
    University of Alabama at Birmingham, Birmingham, AL 35294 3408, USA
    Arthritis Rheum 56:614-21. 2007
    ..To examine the clinical correlates of thrombocytopenia and the value of thrombocytopenia as a predictor of disease activity, damage accrual, and mortality in patients with systemic lupus erythematosus (SLE)...
  93. ncbi Articular manifestations of human immunodeficiency virus infection
    Girish M Mody
    Rheumatology Unit, Nelson R Mandela School of Medicine, Private Bag 7, Congella, Durban 4013, South Africa
    Best Pract Res Clin Rheumatol 17:265-87. 2003
    ..The use of HAART can modify the prevalence or expression of the articular syndromes...
  94. ncbi Systemic lupus erythematosus in a multiethnic US cohort: XXXVI. Influence of mannose-binding lectin exon 1 polymorphisms in disease manifestations, course, and outcome
    Ana M Bertoli
    The University of Alabama at Birmingham, USA
    Arthritis Rheum 54:1703-4. 2006
  95. ncbi Systemic lupus erythematosus in a multiethnic US cohort (LUMINA): XXII. Predictors of time to the occurrence of initial damage
    Sergio M A Toloza
    Schools of Medicine and Public Health, The University of Alabama at Birmingham, 35294-3408, USA
    Arthritis Rheum 50:3177-86. 2004
    ..These results need to be considered when evaluating therapies for SLE...

Research Grants14

  1. Genetics and Ankylosing Spondylitis (AS) Pathogenesis
    John Reveille; Fiscal Year: 2007
    ..To investigate interaction of candidate regions/genes identified in Specific Aim 3 with other MHC and non MHC genes implicated in the risk for AS. ..
  2. Pre-and Postdoctoral Training in the Rheumatic Diseases
    John Reveille; Fiscal Year: 2007
    ..Thus this Program will contribute to a new generation of academic rheumatologists equipped to address challenging problems in rheumatology, genetics and health services research. ..
  3. Spondyloarthritis 2006; The Unmet Needs
    John Reveille; Fiscal Year: 2006
    ....
  4. FAMILY STUDIES OF THE GENETICS OF ANKYLOSING SPONDYLITIS
    John Reveille; Fiscal Year: 2003
    ..abstract_text> ..