Research Topics
Species | Melissa B RamockiSummaryAffiliation: Baylor College of Medicine Country: USA Publications
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Publications
The MECP2 duplication syndromeMelissa B Ramocki
Department of Pediatrics, Baylor College of Medicine, Texas Children s Hospital, Houston, TX 77030, USA
Am J Med Genet A 152:1079-88. 2010..We discuss recommendations for clinical management and surveillance as well as the need for further clinical, genotype-phenotype, and molecular studies to assist the patients and their families who are affected by this syndrome...
Recurrent partial rhombencephalosynapsis and holoprosencephaly in siblings with a mutation of ZIC2Melissa B Ramocki
Division of Pediatric Neurology and Developmental Neuroscience, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA
Am J Med Genet A 155:1574-80. 2011..In addition, an individual with a complex rearrangement of chromosome 22q13.3 and RES was identified, suggesting the presence of a dosage-sensitive gene that may contribute to RES in this region...
A partial MECP2 duplication in a mildly affected adult male: a putative role for the 3' untranslated region in the MECP2 duplication phenotypeNeil A Hanchard
Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
BMC Med Genet 13:71. 2012..Most carrier females show complete skewing of X-inactivation in peripheral blood and an apparent susceptibility to specific personality traits or neuropsychiatric symptoms...
Autism and other neuropsychiatric symptoms are prevalent in individuals with MeCP2 duplication syndromeMelissa B Ramocki
Section of Child Neurology and Developmental Neuroscience, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA
Ann Neurol 66:771-82. 2009..This study characterizes the clinical and neuropsychiatric phenotypes of affected boys and carrier females...
Inverted genomic segments and complex triplication rearrangements are mediated by inverted repeats in the human genomeClaudia M B Carvalho
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA
Nat Genet 43:1074-81. 2011..We propose a mechanism that involves both homology-driven events, via inverted repeats, and microhomologous or nonhomologous events...
Whole-exome sequencing identifies compound heterozygous mutations in WDR62 in siblings with recurrent polymicrogyriaDavid R Murdock
Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, USA
Am J Med Genet A 155:2071-7. 2011..Further studies to identify mutation frequency in the population are needed...
MECP2 duplications in six patients with complex sex chromosome rearrangementsAmy M Breman
Medical Genetics Laboratories, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA
Eur J Hum Genet 19:409-15. 2011....
TGFBR2 deletion in a 20-month-old female with developmental delay and microcephalyIan M Campbell
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA
Am J Med Genet A 155:1442-7. 2011..Moreover, we propose that somatic mosaicism below the detection threshold of FISH analysis in asymptomatic parents of children with genomic disorders may be more common than previously recognized...
Complex rearrangements in patients with duplications of MECP2 can occur by fork stalling and template switchingClaudia M B Carvalho
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA
Hum Mol Genet 18:2188-203. 2009....
Bilateral in utero cerebellar infarctionSafdar A Ansari
Department of Neurology, Baylor College of Medicine and Texas Children s Hospital, Houston, Texas, USA
J Child Neurol 26:895-9. 2011..Such posterior fossa ischemic insults diagnosed in utero are rare with scarce clinical reports. The serial imaging characteristics, clinical, and developmental implications of this case are reviewed...
