Lavanya Rajagopalan

Summary

Affiliation: Baylor College of Medicine
Country: USA

Publications

  1. pmc Glycosylation regulates prestin cellular activity
    Lavanya Rajagopalan
    Bobby R Alford Department of Otolaryngology Head and Neck Surgery, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    J Assoc Res Otolaryngol 11:39-51. 2010
  2. pmc Tuning of the outer hair cell motor by membrane cholesterol
    Lavanya Rajagopalan
    Bobby R Alford Department of Otolaryngology Head and Neck Surgery, Huffington Center on Aging and Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA
    J Biol Chem 282:36659-70. 2007
  3. pmc Functional expression and microdomain localization of prestin in cultured cells
    Angela K Sturm
    Bobby R Alford Department of Otolaryngology Head and Neck Surgery, Baylor College of Medicine, Houston, TX 77030, USA
    Otolaryngol Head Neck Surg 136:434-9. 2007
  4. pmc Membrane composition modulates prestin-associated charge movement
    John Sfondouris
    Bobby R Alford Department of Otolaryngology Head and Neck Surgery, Baylor College of Medicine, Houston, Texas 77030, USA
    J Biol Chem 283:22473-81. 2008
  5. pmc Prestin modulates mechanics and electromechanical force of the plasma membrane
    Rui Zhang
    Applied Physics Graduate Program, Rice University, Houston, Texas, USA
    Biophys J 93:L07-9. 2007
  6. pmc Identification of functionally important residues/domains in membrane proteins using an evolutionary approach coupled with systematic mutational analysis
    Lavanya Rajagopalan
    Bobby R Alford Department of Otolaryngology HNS, Baylor College of Medicine, Houston, TX, USA
    Methods Mol Biol 493:287-97. 2009
  7. pmc Essential helix interactions in the anion transporter domain of prestin revealed by evolutionary trace analysis
    Lavanya Rajagopalan
    Department of Molecular Virology, Baylor College of Medicine, Houston, Texas 77030, USA
    J Neurosci 26:12727-34. 2006

Collaborators

Detail Information

Publications7

  1. pmc Glycosylation regulates prestin cellular activity
    Lavanya Rajagopalan
    Bobby R Alford Department of Otolaryngology Head and Neck Surgery, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    J Assoc Res Otolaryngol 11:39-51. 2010
    ..We speculate that the cholesterol regulation of prestin occurs through localization to and internalization from membrane microdomains by clathrin- and caveolin-dependent mechanisms...
  2. pmc Tuning of the outer hair cell motor by membrane cholesterol
    Lavanya Rajagopalan
    Bobby R Alford Department of Otolaryngology Head and Neck Surgery, Huffington Center on Aging and Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA
    J Biol Chem 282:36659-70. 2007
    ..These findings indicate that alterations in membrane cholesterol affect prestin function and functionally tune the outer hair cell...
  3. pmc Functional expression and microdomain localization of prestin in cultured cells
    Angela K Sturm
    Bobby R Alford Department of Otolaryngology Head and Neck Surgery, Baylor College of Medicine, Houston, TX 77030, USA
    Otolaryngol Head Neck Surg 136:434-9. 2007
    ..A model system to study prestin employs its transfection into cultured HEK 293 cells. Our goal was to characterize prestin's trafficking pathway and localization in the plasma membrane...
  4. pmc Membrane composition modulates prestin-associated charge movement
    John Sfondouris
    Bobby R Alford Department of Otolaryngology Head and Neck Surgery, Baylor College of Medicine, Houston, Texas 77030, USA
    J Biol Chem 283:22473-81. 2008
    ..Our results quantify the relation between membrane cholesterol concentration and prestin-associated charge movement and enhance our understanding of how membrane composition modulates prestin function...
  5. pmc Prestin modulates mechanics and electromechanical force of the plasma membrane
    Rui Zhang
    Applied Physics Graduate Program, Rice University, Houston, Texas, USA
    Biophys J 93:L07-9. 2007
    ..These results suggest that prestin-associated charge transfer is necessary for maximal EMF generation by the membrane...
  6. pmc Identification of functionally important residues/domains in membrane proteins using an evolutionary approach coupled with systematic mutational analysis
    Lavanya Rajagopalan
    Bobby R Alford Department of Otolaryngology HNS, Baylor College of Medicine, Houston, TX, USA
    Methods Mol Biol 493:287-97. 2009
    ....
  7. pmc Essential helix interactions in the anion transporter domain of prestin revealed by evolutionary trace analysis
    Lavanya Rajagopalan
    Department of Molecular Virology, Baylor College of Medicine, Houston, Texas 77030, USA
    J Neurosci 26:12727-34. 2006
    ..These data suggest that packing of helices and interactions between residues surrounding the "sulfate transporter motif" is essential for normal prestin activity...