Sharon Plon

Summary

Affiliation: Baylor College of Medicine
Country: USA

Publications

  1. pmc Sequence variant classification and reporting: recommendations for improving the interpretation of cancer susceptibility genetic test results
    Sharon E Plon
    Department of Pediatrics, Baylor Cancer Genetics Clinic, Baylor College of Medicine, Houston, Texas, USA
    Hum Mutat 29:1282-91. 2008
  2. pmc Genetic testing and cancer risk management recommendations by physicians for at-risk relatives
    Sharon E Plon
    Department of Pediatrics, Dan L Duncan Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA
    Genet Med 13:148-54. 2011
  3. pmc Identification of genetic susceptibility to childhood cancer through analysis of genes in parallel
    Sharon E Plon
    Texas Children s Cancer Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA
    Cancer Genet 204:19-25. 2011
  4. doi request reprint Outcomes of integrating genetics in management of patients with retinoblastoma
    Shweta U Dhar
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA
    Arch Ophthalmol 129:1428-34. 2011

Collaborators

Detail Information

Publications4

  1. pmc Sequence variant classification and reporting: recommendations for improving the interpretation of cancer susceptibility genetic test results
    Sharon E Plon
    Department of Pediatrics, Baylor Cancer Genetics Clinic, Baylor College of Medicine, Houston, Texas, USA
    Hum Mutat 29:1282-91. 2008
    ..The international adoption of a standardized reporting system should improve the clinical utility of sequence-based genetic tests to predict cancer risk...
  2. pmc Genetic testing and cancer risk management recommendations by physicians for at-risk relatives
    Sharon E Plon
    Department of Pediatrics, Dan L Duncan Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA
    Genet Med 13:148-54. 2011
    ..Sequence-based cancer susceptibility testing results are described as negative, deleterious mutation or variant of uncertain significance. We studied the impact of different types of test results on clinical decision making...
  3. pmc Identification of genetic susceptibility to childhood cancer through analysis of genes in parallel
    Sharon E Plon
    Texas Children s Cancer Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA
    Cancer Genet 204:19-25. 2011
    ..The failure to detect mutations in 87% of families highlights that a number of childhood cancer susceptibility genes remain to be discovered...
  4. doi request reprint Outcomes of integrating genetics in management of patients with retinoblastoma
    Shweta U Dhar
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA
    Arch Ophthalmol 129:1428-34. 2011
    ..To present the outcome of a comprehensive team approach to provide genetic evaluation and testing for a large cohort of children diagnosed with retinoblastoma...

Research Grants15

  1. Do Physicians Understand Uncertain Variants and Other Genetic Test Results?
    Sharon Plon; Fiscal Year: 2009
    ..With the increasing availability of complex testing modalities, e.g. DNA and RNA gene chips, for a variety of both rare and common diseases, appropriate reporting and physician education must accompany the development of these tests. ..
  2. Do Physicians Understand Uncertain Variants and Other Genetic Test Results?
    Sharon Plon; Fiscal Year: 2007
    ..With the increasing availability of complex testing modalities, e.g. DNA and RNA gene chips, for a variety of both rare and common diseases, appropriate reporting and physician education must accompany the development of these tests. ..
  3. MEDICAL SCIENTIST TRAINING PROGRAM
    Sharon Plon; Fiscal Year: 2007
    ..He is supported by three Co-Directors: Jeffrey M. Rosen, PhD, Martin M. Matzuk, MD, PhD, and Sharon Plon, MD, PhD. Three of the four program directors received their training through NIH MSTPs (Dr. Lupski at NYU, Dr...
  4. MOLECULAR ANALYSIS OF FANCONI'S ANEMIA C PROTEIN
    Sharon Plon; Fiscal Year: 2003
    ....
  5. ALTERNATIVE DNA DAMAGE CHECKPOINT PATHWAYS IN EUKARYOTES
    Sharon Plon; Fiscal Year: 2002
    ..These latter results will demonstrate whether activation of an alternative checkpoint pathway might be used therapeutically for patients with AT or to alter the resistance of tumors to radiation and other DNA-damaging agents. ..
  6. Genomic Approaches to Defining Inherited Basis of Childhood Cancer
    SHARON EMMA PLON; Fiscal Year: 2010
    ....