Affiliation: Baylor College of Medicine
- Sequence variant classification and reporting: recommendations for improving the interpretation of cancer susceptibility genetic test resultsSharon E Plon
Department of Pediatrics, Baylor Cancer Genetics Clinic, Baylor College of Medicine, Houston, Texas, USA
Hum Mutat 29:1282-91. 2008..The international adoption of a standardized reporting system should improve the clinical utility of sequence-based genetic tests to predict cancer risk...
- Genetic testing and cancer risk management recommendations by physicians for at-risk relativesSharon E Plon
Department of Pediatrics, Dan L Duncan Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA
Genet Med 13:148-54. 2011..Sequence-based cancer susceptibility testing results are described as negative, deleterious mutation or variant of uncertain significance. We studied the impact of different types of test results on clinical decision making...
- Identification of genetic susceptibility to childhood cancer through analysis of genes in parallelSharon E Plon
Texas Children s Cancer Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA
Cancer Genet 204:19-25. 2011..The failure to detect mutations in 87% of families highlights that a number of childhood cancer susceptibility genes remain to be discovered...
- Outcomes of integrating genetics in management of patients with retinoblastomaShweta U Dhar
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA
Arch Ophthalmol 129:1428-34. 2011..To present the outcome of a comprehensive team approach to provide genetic evaluation and testing for a large cohort of children diagnosed with retinoblastoma...